By Dr Clara Catherine Young

Journal articles

Young C; Singh M; Jackson KJL; Field MA; Peters TJ; Angioletti-Uberti S; Frenkel D; Ravishankar S; Gupta M; Wang JJ; Agapiou D; Faulks ML; Al-Eryani G; Luciani F; Gordon TP; Reed JH; Danta M; Carr A; Kelleher AD; Dore GJ; Matthews G; Brink R; Bull RA; Suan D; Goodnow CC, 2025, 'A triad of somatic mutagenesis converges in self-reactive B cells to cause a virus-induced autoimmune disease', Immunity, 58, pp. 412 - 430.e10, http://dx.doi.org/10.1016/j.immuni.2024.12.011

Young C; Lau AWY; Burnett DL, 2022, 'B cells in the balance: Offsetting self-reactivity avoidance with protection against foreign', Frontiers in Immunology, 13, http://dx.doi.org/10.3389/fimmu.2022.951385

Young C; Brink R, 2021, 'The unique biology of germinal center B cells', Immunity, 54, pp. 1652 - 1664, http://dx.doi.org/10.1016/j.immuni.2021.07.015

Sundling C; Lau AWY; Bourne K; Young C; Laurianto C; Hermes JR; Menzies RJ; Butt D; Kräutler NJ; Zahra D; Suan D; Brink R, 2021, 'Positive selection of IgG+ over IgM+ B cells in the germinal center reaction', Immunity, 54, pp. 988 - 1001.e5, http://dx.doi.org/10.1016/j.immuni.2021.03.013

Young C; Brink R, 2020, 'Germinal centers and autoantibodies', Immunology and Cell Biology, 98, pp. 480 - 489, http://dx.doi.org/10.1111/imcb.12321

Moran I; Nguyen A; Khoo WH; Butt D; Bourne K; Young C; Hermes JR; Biro M; Gracie G; Ma CS; Munier CML; Luciani F; Zaunders J; Parker A; Kelleher AD; Tangye SG; Croucher PI; Brink R; Read MN; Phan TG, 2018, 'Memory B cells are reactivated in subcapsular proliferative foci of lymph nodes', Nature Communications, 9, pp. 3372, http://dx.doi.org/10.1038/s41467-018-05772-7

Suan D; Kräutler NJ; Maag JLV; Butt D; Bourne K; Hermes JR; Avery DT; Young C; Statham A; Elliott M; Dinger ME; Basten A; Tangye SG; Brink R, 2017, 'CCR6 Defines Memory B Cell Precursors in Mouse and Human Germinal Centers, Revealing Light-Zone Location and Predominant Low Antigen Affinity', Immunity, 47, pp. 1142 - 1153.e4, http://dx.doi.org/10.1016/j.immuni.2017.11.022

Sabouri Z; Perotti S; Spierings E; Humburg P; Yabas M; Bergmann H; Horikawa K; Roots C; Lambe S; Young C; Andrews TD; Field M; Enders A; Reed JH; Goodnow CC, 2016, 'IgD attenuates the IgM-induced anergy response in transitional and mature B cells', Nature Communications, 7, http://dx.doi.org/10.1038/ncomms13381

Preprints

Young C; Singh M; Jackson KJL; Field MA; Peters TJ; Angioletti-Uberti S; Frenkel D; Ravishankar S; Gupta M; Wang JJ; Agapiou D; Faulks ML; Al-Eryani G; Luciani F; Gordon TP; Reed JH; Danta M; Carr A; Kelleher AD; Dore GJ; Matthews G; Brink R; Bull RA; Suan D; Goodnow CC, 2024, Self-reactive B cells traverse a perfect storm of somatic mutagenesis to cause a virus-induced autoimmune disease, http://dx.doi.org/10.1101/2024.01.07.574561

Boast B; Helian K; Andrews D; Li X; Cho V; Closa A; Sutton H; Reed J; Bergmann H; Roots C; Yabas M; Barthel N; Omari S; Young C; Miosge L; Eyras E; Nutt S; Hein N; Hannan K; Cockburn I; Goodnow C; Enders A, 2021, Dysregulation of PAX5 causes uncommitted B cell development and tumorigenesis in mice, http://dx.doi.org/10.1101/2021.01.29.428877

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