By Dr David Samuel Khoury

Journal articles

Rebelo M; Pawliw R; Gower J; Webb L; Mitchell H; Pava Z; Watts RE; Davenport MP; McCarthy JS; Khoury DS, 2021, 'Parasite Viability as a Superior Measure of Antimalarial Drug Activity in Humans', Journal of Infectious Diseases, 223, pp. 2154 - 2163, http://dx.doi.org/10.1093/infdis/jiaa678

Cromer D; Juno JA; Khoury D; Reynaldi A; Wheatley AK; Kent SJ; Davenport MP, 2021, 'Prospects for durable immune control of SARS-CoV-2 and prevention of reinfection', Nature Reviews Immunology, 21, pp. 395 - 404, http://dx.doi.org/10.1038/s41577-021-00550-x

Khoury DS; Wheatley AK; Ramuta MD; Reynaldi A; Cromer D; Subbarao K; O’Connor DH; Kent SJ; Davenport MP, 2020, 'Measuring immunity to SARS-CoV-2 infection: comparing assays and animal models', Nature Reviews Immunology, 20, pp. 727 - 738, http://dx.doi.org/10.1038/s41577-020-00471-1

Soon MSF; Lee HJ; Engel JA; Straube J; Thomas BS; Pernold CPS; Clarke LS; Laohamonthonkul P; Haldar RN; Williams CG; Lansink LIM; Moreira ML; Bramhall M; Koufariotis LT; Wood S; Chen X; James KR; Lönnberg T; Lane SW; Belz GT; Engwerda CR; Khoury DS; Davenport MP; Svensson V; Teichmann SA; Haque A, 2020, 'Transcriptome dynamics of CD4+ T cells during malaria maps gradual transit from effector to memory.', Nature Immunology, 21, pp. 1597 - 1610, http://dx.doi.org/10.1038/s41590-020-0800-8

Khoury DS; Cao P; Zaloumis SG; Davenport MP, 2020, 'Artemisinin Resistance and the Unique Selection Pressure of a Short-acting Antimalarial', Trends in Parasitology, 36, pp. 884 - 887, http://dx.doi.org/10.1016/j.pt.2020.07.004

Corder RM; de Lima ACP; Khoury DS; Docken SS; Davenport MP; Ferreira MU, 2020, 'Quantifying and preventing plasmodium vivax recurrences in primaquine-untreated pregnant women: An observational and modeling study in Brazil', Plos Neglected Tropical Diseases, 14, pp. 1 - 16, http://dx.doi.org/10.1371/journal.pntd.0008526

Collins KA; Wang CYT; Adams M; Mitchell H; Robinson GJ; Rampton M; Elliott S; Odedra A; Khoury D; Ballard E; Shelper TB; Lucantoni L; Avery VM; Chalon S; Moehrle JJ; McCarthy JS, 2020, 'A Plasmodium vivax experimental human infection model for evaluating efficacy of interventions', Journal of Clinical Investigation, 130, pp. 2920 - 2927, http://dx.doi.org/10.1172/JCI134923

Khoury DS; Zaloumis SG; Grigg MJ; Haque A; Davenport MP; Cromer D; Rebelo M; Cao P; McCaw JM; Simpson JA; Flegg JA; Wilson DW; Anstey NM; McCarthy JS, 2020, 'Malaria Parasite Clearance: What Are We Really Measuring?', Trends in Parasitology, 36, pp. 413 - 426, http://dx.doi.org/10.1016/j.pt.2020.02.005

Khoury DS; Cromer D; Möhrle JJ; McCarthy JS; Davenport MP, 2019, 'Corrigendum: Defining the effectiveness of antimalarial chemotherapy: Investigation of the lag in parasite clearance following drug administration (Journal of Infectious Diseases (2016) 214 (753-761) DOI: 10.1093/infdis/jiw234)', Journal of Infectious Diseases, 219, pp. 1852 - 1853, http://dx.doi.org/10.1093/infdis/jiy729

Akter J; Khoury DS; Aogo R; Lansink LIM; SheelaNair A; Thomas BS; Laohamonthonkul P; Pernold CPS; Dixon MWA; Soon MSF; Fogg LG; Engel JA; Elliott T; Sebina I; James KR; Cromer D; Davenport MP; Haque A, 2019, 'Plasmodium-specific antibodies block in vivo parasite growth without clearing infected red blood cells', Plos Pathogens, 15, pp. e1007599, http://dx.doi.org/10.1371/journal.ppat.1007599

Davenport MP; Khoury DS; Cromer D; Lewin SR; Kelleher AD; Kent SJ, 2019, 'Functional cure of HIV: the scale of the challenge', Nature Reviews Immunology, 19, pp. 45 - 54, http://dx.doi.org/10.1038/s41577-018-0085-4

Betts M; Kuri Cervantes L; Pampena MB; Samer S; Khoury D; Frank I; Paiardini M; Davenport M; Bar K; Veazey R, 2019, 'Peripheral blood SIV/HIV originates from infected cells in tissues', Journal of Virus Eradication, 5, pp. 27 - 27, http://dx.doi.org/10.1016/s2055-6640(20)30142-4

Zaloumis SG; Cao P; Dini S; Davenport MP; Cromer D; Khoury DS; Fowkes FJI; McCaw JM; Simpson JA, 2018, 'In silico investigation of the decline in clinical efficacy of artemisinin combination therapies due to increasing artemisinin and partner drug resistance', Antimicrobial Agents and Chemotherapy, 62, pp. 10.1128/aac.01292 - 10.1128/aac.01218, http://dx.doi.org/10.1128/AAC.01292-18

Aogo RA; Khoury DS; Cromer D; Elliott T; Akter J; Fogg LG; Nair AS; Liligeto UN; Soon MSF; Thomas BS; Pernold CPS; Romanczuk AS; Laohamonthonkul P; Haque A; Davenport MP, 2018, 'Quantification of host-mediated parasite clearance during blood-stage Plasmodium infection and anti-malarial drug treatment in mice', International Journal for Parasitology, 48, pp. 903 - 913, http://dx.doi.org/10.1016/j.ijpara.2018.05.010

Khoury DS; Aogo R; Randriafanomezantsoa-Radohery G; McCaw JM; Simpson JA; McCarthy JS; Haque A; Cromer D; Davenport MP, 2018, 'Within-host modeling of blood-stage malaria', Immunological Reviews, 285, pp. 168 - 193, http://dx.doi.org/10.1111/imr.12697

Khoury DS; Cromer D; Elliott T; Soon MSF; Thomas BS; James KR; Best SE; Aogo RA; Engel JA; Gartlan KH; Akter J; Sebina I; Haque A; Davenport MP, 2017, 'Characterising the effect of antimalarial drugs on the maturation and clearance of murine blood-stage Plasmodium parasites in vivo', International Journal for Parasitology, 47, pp. 913 - 922, http://dx.doi.org/10.1016/j.ijpara.2017.05.009

Cao P; Klonis N; Zaloumis S; Khoury DS; Cromer D; Davenport MP; Tilley L; Simpson JA; McCaw JM, 2017, 'A mechanistic model quantifies artemisinin-induced parasite growth retardation in blood-stage Plasmodium falciparum infection', Journal of Theoretical Biology, 430, pp. 117 - 127, http://dx.doi.org/10.1016/j.jtbi.2017.07.017

Khoury DS; Cromer D; Akter J; Sebina I; Elliott T; Thomas BS; Soon MSF; James KR; Best SE; Haque A; Davenport MP, 2017, 'Host-mediated impairment of parasite maturation during blood-stage Plasmodium infection', Proceedings of the National Academy of Sciences of the United States of America, 114, pp. 7701 - 7706, http://dx.doi.org/10.1073/pnas.1618939114

Griffin P; Pasay C; Elliott S; Sekuloski S; Sikulu M; Hugo L; Khoury D; Cromer D; Davenport M; Sattabongkot J; Ivinson K; Ockenhouse C; McCarthy J, 2016, 'Safety and Reproducibility of a Clinical Trial System Using Induced Blood Stage Plasmodium vivax Infection and Its Potential as a Model to Evaluate Malaria Transmission', Plos Neglected Tropical Diseases, 10, pp. e0005139, http://dx.doi.org/10.1371/journal.pntd.0005139

Khoury DS; Cromer D; Möhrle JJ; McCarthy JS; Davenport MP, 2016, 'Defining the effectiveness of antimalarial chemotherapy: Investigation of the lag in parasite clearance following drug administration', Journal of Infectious Diseases, 214, pp. 753 - 761, http://dx.doi.org/10.1093/infdis/jiw234

Khoury DS; Cromer D; Best SE; James KR; Sebina I; Haque A; Davenport MP, 2015, 'Reduced erythrocyte susceptibility and increased host clearance of young parasites slows Plasmodium growth in a murine model of severe malaria', Scientific Reports, 5, pp. 9412, http://dx.doi.org/10.1038/srep09412

Khoury DS; Cromer D; Best SE; James KR; Kim PS; Engwerda CR; Haque A; Davenport MP, 2014, 'Effect of mature blood-stage Plasmodium parasite sequestration on pathogen biomass in mathematical and in vivo models of malaria.', Infect Immun, 82, pp. 212 - 220, http://dx.doi.org/10.1128/IAI.00705-13

Delaney GW; Khoury D, 2013, 'Onset of rigidity in 3D stretched string networks', European Physical Journal B, 86, http://dx.doi.org/10.1140/epjb/e2012-30445-y

Khoury DS; Barron AB; Myerscough MR, 2013, 'Modelling food and population dynamics in honey bee colonies.', PLoS One, 8, pp. e59084, http://dx.doi.org/10.1371/journal.pone.0059084

Khoury DS; Myerscough MR; Barron AB, 2011, 'A quantitative model of honey bee colony population dynamics', Plos One, 6, http://dx.doi.org/10.1371/journal.pone.0018491

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