By Dr David Samuel Khoury

Journal articles

Ashley CL; Bloul M; Alca S; Smith L; Jin W; Khoury D; Counoupas C; Davenport M; Triccas JA; Steain M, 2025, 'Optimisation of a multiplexed, high throughput assay to measure neutralising antibodies against SARS-CoV-2 variants', Journal of Virological Methods, 332, http://dx.doi.org/10.1016/j.jviromet.2024.115073

Cromer D; Reynaldi A; Mitchell A; Schlub TE; Juno JA; Wheatley AK; Kent SJ; Khoury DS; Davenport MP, 2024, 'Predicting COVID-19 booster immunogenicity against future SARS-CoV-2 variants and the benefits of vaccine updates', Nature Communications, 15, http://dx.doi.org/10.1038/s41467-024-52194-9

Berry MT; Khan SR; Schlub TE; Notaras A; Kunasekaran M; Grulich AE; MacIntyre CR; Davenport MP; Khoury DS, 2024, 'Predicting vaccine effectiveness for mpox', Nature Communications, 15, pp. 3856, http://dx.doi.org/10.1038/s41467-024-48180-w

Williams CG; Moreira ML; Asatsuma T; Lee HJ; Li S; Burn TN; Barrera I; Murray E; Soon MSF; Engel JA; Khoury DS; Le S; Wanrooy BJ; Schienstock D; Alexandre YO; Skinner OP; Joseph R; Beattie L; Mueller SN; Chen F; Haque A, 2024, 'Erratum: Plasmodium infection induces phenotypic, clonal, and spatial diversity among differentiating CD4⁺ T cells (Cell Reports (2024) 43(6), (S2211124724006454), (10.1016/j.celrep.2024.114317))', Cell Reports, 43, http://dx.doi.org/10.1016/j.celrep.2024.114754

Williams CG; Moreira ML; Asatsuma T; Lee HJ; Li S; Barrera I; Murray E; Soon MSF; Engel JA; Khoury DS; Le S; Wanrooy BJ; Schienstock D; Alexandre YO; Skinner OP; Joseph R; Beattie L; Mueller SN; Chen F; Haque A, 2024, 'Plasmodium infection induces phenotypic, clonal, and spatial diversity among differentiating CD4⁺ T cells', Cell Reports, 43, http://dx.doi.org/10.1016/j.celrep.2024.114317

Elias KM; Khan SR; Stadler E; Schlub TE; Cromer D; Polizzotto MN; Kent SJ; Turner T; Davenport MP; Khoury DS, 2024, 'Viral clearance as a surrogate of clinical efficacy for COVID-19 therapies in outpatients: a systematic review and meta-analysis', The Lancet Microbe, 5, pp. e459 - e467, http://dx.doi.org/10.1016/S2666-5247(23)00398-1

Stadler E; Maiga M; Friedrich L; Thathy V; Demarta-Gatsi C; Dara A; Sogore F; Striepen J; Oeuvray C; Djimdé AA; Lee MCS; Dembélé L; Fidock DA; Khoury DS; Spangenberg T, 2023, 'Author Correction: Propensity of selecting mutant parasites for the antimalarial drug cabamiquine (Nature Communications, (2023), 14, 1, (5205), 10.1038/s41467-023-40974-8)', Nature Communications, 14, http://dx.doi.org/10.1038/s41467-023-41287-6

Hogan AB; Doohan P; Wu SL; Mesa DO; Toor J; Watson OJ; Winskill P; Charles G; Barnsley G; Riley EM; Khoury DS; Ferguson NM; Ghani AC, 2023, 'Estimating long-term vaccine effectiveness against SARS-CoV-2 variants: a model-based approach', Nature Communications, 14, pp. 4325, http://dx.doi.org/10.1038/s41467-023-39736-3

Stadler E; Cromer D; Ogunlade S; Ongoiba A; Doumbo S; Kayentao K; Traore B; Crompton PD; Portugal S; Davenport MP; Khoury DS, 2023, 'Evidence for exposure dependent carriage of malaria parasites across the dry season: modelling analysis of longitudinal data', Malaria Journal, 22, http://dx.doi.org/10.1186/s12936-023-04461-1

Stadler E; Burgess MT; Schlub TE; Khan SR; Chai KL; McQuilten ZK; Wood EM; Polizzotto MN; Kent SJ; Cromer D; Davenport MP; Khoury DS, 2023, 'Monoclonal antibody levels and protection from COVID-19', Nature Communications, 14, pp. 4545, http://dx.doi.org/10.1038/s41467-023-40204-1

Cromer D; Steain M; Reynaldi A; Schlub TE; Khan SR; Sasson SC; Kent SJ; Khoury DS; Davenport MP, 2023, 'Predicting vaccine effectiveness against severe COVID-19 over time and against variants: a meta-analysis', Nature Communications, 14, pp. 1633, http://dx.doi.org/10.1038/s41467-023-37176-7

Stadler E; Maiga M; Friedrich L; Thathy V; Demarta-Gatsi C; Dara A; Sogore F; Striepen J; Oeuvray C; Djimdé AA; Lee MCS; Dembélé L; Fidock DA; Khoury DS; Spangenberg T, 2023, 'Propensity of selecting mutant parasites for the antimalarial drug cabamiquine', Nature Communications, 14, http://dx.doi.org/10.1038/s41467-023-40974-8

Stadler E; Chai KL; Schlub TE; Cromer D; Khan SR; Polizzotto MN; Kent SJ; Beecher C; White H; Turner T; Skoetz N; Estcourt L; McQuilten ZK; Wood EM; Khoury DS; Davenport MP, 2023, 'Determinants of passive antibody efficacy in SARS-CoV-2 infection: a systematic review and meta-analysis', The Lancet Microbe, 4, pp. e883 - e892, http://dx.doi.org/10.1016/S2666-5247(23)00194-5

Hogan AB; Wu SL; Toor J; Mesa DO; Doohan P; Watson OJ; Winskill P; Charles G; Barnsley G; Riley EM; Khoury DS; Ferguson NM; Ghani AC, 2023, 'Long-term vaccination strategies to mitigate the impact of SARS-CoV-2 transmission: A modelling study', PLoS Medicine, 20, pp. e1004195, http://dx.doi.org/10.1371/journal.pmed.1004195

Lansink LIM; Skinner OP; Engel JA; Lee HJ; Soon MSF; Williams CG; SheelaNair A; Pernold CPS; Laohamonthonkul P; Akter J; Stoll T; Hill MM; Talman AM; Russell A; Lawniczak M; Jia X; Chua B; Anderson D; Creek DJ; Davenport MP; Khoury DS; Haque A, 2023, 'Systemic host inflammation induces stage-specific transcriptomic modification and slower maturation in malaria parasites', mBio, 14, pp. e0112923, http://dx.doi.org/10.1128/mbio.01129-23

Lee WS; Tan HX; Reynaldi A; Esterbauer R; Koutsakos M; Nguyen J; Amarasena T; Kent HE; Aggarwal A; Turville SG; Taiaroa G; Kinsella P; Liew KC; Tran T; Williamson DA; Cromer D; Davenport MP; Kent SJ; Juno JA; Khoury DS; Wheatley AK, 2023, 'Durable reprogramming of neutralizing antibody responses following Omicron breakthrough infection', Science Advances, 9, http://dx.doi.org/10.1126/sciadv.adg5301

Zhang W; Kedzierski L; Chua BY; Mayo M; Lonzi C; Rigas V; Middleton BF; McQuilten HA; Rowntree LC; Allen LF; Purcell RA; Tan HX; Petersen J; Chaurasia P; Mordant F; Pogorelyy MV; Minervina AA; Crawford JC; Perkins GB; Zhang E; Gras S; Clemens EB; Juno JA; Audsley J; Khoury DS; Holmes NE; Thevarajan I; Subbarao K; Krammer F; Cheng AC; Davenport MP; Grubor-Bauk B; Coates PT; Christensen B; Thomas PG; Wheatley AK; Kent SJ; Rossjohn J; Chung AW; Boffa J; Miller A; Lynar S; Nelson J; Nguyen THO; Davies J; Kedzierska K, 2023, 'Robust and prototypical immune responses toward COVID-19 vaccine in First Nations peoples are impacted by comorbidities', Nature Immunology, 24, pp. 966 - 978, http://dx.doi.org/10.1038/s41590-023-01508-y

Koutsakos M; Reynaldi A; Lee WS; Nguyen J; Amarasena T; Taiaroa G; Kinsella P; Liew KC; Tran T; Kent HE; Tan HX; Rowntree LC; Nguyen THO; Thomas PG; Kedzierska K; Petersen J; Rossjohn J; Williamson DA; Khoury D; Davenport MP; Kent SJ; Wheatley AK; Juno JA, 2023, 'SARS-CoV-2 breakthrough infection induces rapid memory and de novo T cell responses', Immunity, 56, pp. 879 - 892.e4, http://dx.doi.org/10.1016/j.immuni.2023.02.017

Khoury DS; Docken SS; Subbarao K; Kent SJ; Davenport MP; Cromer D, 2023, 'Predicting the efficacy of variant-modified COVID-19 vaccine boosters', Nature Medicine, 29, pp. 574 - 578, http://dx.doi.org/10.1038/s41591-023-02228-4

Khoury DS; Schlub TE; Cromer D; Steain M; Fong Y; Gilbert PB; Subbarao K; Triccas JA; Kent SJ; Davenport MP, 2023, 'Correlates of Protection, Thresholds of Protection, and Immunobridging among Persons with SARS-CoV-2 Infection', Emerging Infectious Diseases, 29, pp. 381 - 388, http://dx.doi.org/10.3201/eid2902.221422

Parkyn Schneider M; Looker O; Rebelo M; Khoury DS; Dixon MWA; Oeuvray C; Crabb BS; McCarthy J; Gilson PR, 2023, 'The delayed bloodstream clearance of Plasmodium falciparum parasites after M5717 treatment is attributable to the inability to modify their red blood cell hosts', Frontiers in Cellular and Infection Microbiology, 13, http://dx.doi.org/10.3389/fcimb.2023.1211613

Stadler E; Cromer D; Mehra S; Adekunle AI; Flegg JA; Anstey NM; Watson JA; Chu CS; Mueller I; Robinson LJ; Schlub TE; Davenport MP; Khoury DS, 2022, 'Population heterogeneity in Plasmodium vivax relapse risk', PLoS Neglected Tropical Diseases, 16, http://dx.doi.org/10.1371/journal.pntd.0010990

SheelaNair A; Romanczuk AS; Aogo RA; Haldar RN; Lansink LIM; Cromer D; Salinas YG; Guy RK; McCarthy JS; Davenport MP; Haque A; Khoury DS, 2022, 'Similarly efficacious anti-malarial drugs SJ733 and pyronaridine differ in their ability to remove circulating parasites in mice', Malaria Journal, 21, http://dx.doi.org/10.1186/s12936-022-04075-z

Koutsakos M; Lee WS; Reynaldi A; Tan HX; Gare G; Kinsella P; Liew KC; Taiaroa G; Williamson DA; Kent HE; Stadler E; Cromer D; Khoury DS; Wheatley AK; Juno JA; Davenport MP; Kent SJ, 2022, 'The magnitude and timing of recalled immunity after breakthrough infection is shaped by SARS-CoV-2 variants', Immunity, 55, pp. 1316 - 1326.e4, http://dx.doi.org/10.1016/j.immuni.2022.05.018

Radohery GFR; Walz A; Gumpp C; Cherkaoui-Rbati MH; Gobeau N; Gower J; Davenport MP; Rottmann M; McCarthy JS; Möhrle JJ; Rebelo M; Demarta-Gatsi C; Khoury DS, 2022, 'Parasite Viability as a Measure of in Vivo Drug Activity in Preclinical and Early Clinical Antimalarial Drug Assessment', Antimicrobial Agents and Chemotherapy, 66, http://dx.doi.org/10.1128/aac.00114-22

Cromer D; Reynaldi A; Steain M; Triccas JA; Davenport MP; Khoury DS, 2022, 'Relating in Vitro Neutralization Level and Protection in the CVnCoV (CUREVAC) Trial', Clinical Infectious Diseases, 75, pp. E878 - E879, http://dx.doi.org/10.1093/cid/ciac075

Kent SJ; Khoury DS; Reynaldi A; Juno JA; Wheatley AK; Stadler E; John Wherry E; Triccas J; Sasson SC; Cromer D; Davenport MP, 2022, 'Disentangling the relative importance of T cell responses in COVID-19: leading actors or supporting cast?', Nature Reviews Immunology, 22, pp. 387 - 397, http://dx.doi.org/10.1038/s41577-022-00716-1

Radohery GFR; Gower J; Barber BE; Kansagra K; Möhrle JJ; Davenport MP; McCarthy JS; Khoury DS; Rebelo M, 2022, 'Effect of novel antimalarial ZY-19489 on Plasmodium falciparum viability in a volunteer infection study', The Lancet Infectious Diseases, 22, pp. 760 - 761, http://dx.doi.org/10.1016/S1473-3099(22)00294-8

Aggarwal A; Stella AO; Walker G; Akerman A; Esneau C; Milogiannakis V; Burnett DL; McAllery S; Silva MR; Lu Y; Foster CSP; Brilot F; Pillay A; Van Hal S; Mathivanan V; Fichter C; Kindinger A; Hoppe AC; Munier ML; Amatayakul-Chantler S; Roth N; Coppola G; Symonds GP; Schofield P; Jackson J; Lenthall H; Henry JY; Mazigi O; Jäck HM; Davenport MP; Darley DR; Matthews GV; Khoury DS; Cromer D; Goodnow CC; Christ D; Robosa R; Starck DJ; Bartlett NW; Rawlinson WD; Kelleher AD; Turville SG, 2022, 'Platform for isolation and characterization of SARS-CoV-2 variants enables rapid characterization of Omicron in Australia', Nature Microbiology, 7, pp. 896 - 908, http://dx.doi.org/10.1038/s41564-022-01135-7

Goel RR; Painter MM; Lundgreen KA; Apostolidis SA; Baxter AE; Giles JR; Mathew D; Pattekar A; Reynaldi A; Khoury DS; Gouma S; Hicks P; Dysinger S; Hicks A; Sharma H; Herring S; Korte S; KC W; Oldridge DA; Erickson RI; Weirick ME; McAllister CM; Awofolaju M; Tanenbaum N; Dougherty J; Long S; D'Andrea K; Hamilton JT; McLaughlin M; Williams JC; Adamski S; Kuthuru O; Drapeau EM; Davenport MP; Hensley SE; Bates P; Greenplate AR; Wherry EJ, 2022, 'Efficient recall of Omicron-reactive B cell memory after a third dose of SARS-CoV-2 mRNA vaccine', Cell, 185, pp. 1875 - 1887.e8, http://dx.doi.org/10.1016/j.cell.2022.04.009

Mehra S; Stadler E; Khoury D; McCaw JM; Flegg JA, 2022, 'Hypnozoite dynamics for Plasmodium vivax malaria: The epidemiological effects of radical cure', Journal of Theoretical Biology, 537, http://dx.doi.org/10.1016/j.jtbi.2022.111014

Cele S; Jackson L; Khoury DS; Khan K; Moyo-Gwete T; Tegally H; San JE; Cromer D; Scheepers C; Amoako DG; Karim F; Bernstein M; Lustig G; Archary D; Smith M; Ganga Y; Jule Z; Reedoy K; Hwa SH; Giandhari J; Blackburn JM; Gosnell BI; Abdool Karim SS; Hanekom W; Davies MA; Hsiao M; Martin D; Mlisana K; Wibmer CK; Williamson C; York D; Harrichandparsad R; Herbst K; Jeena P; Khoza T; Kløverpris H; Leslie A; Madansein R; Magula N; Manickchund N; Marakalala M; Mazibuko M; Moshabela M; Mthabela N; Naidoo K; Ndhlovu Z; Ndung’u T; Ngcobo N; Nyamande K; Patel V; Smit T; Steyn A; Wong E; von Gottberg A; Bhiman JN; Lessells RJ; Moosa MYS; Davenport MP; de Oliveira T; Moore PL; Sigal A, 2022, 'Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization', Nature, 602, pp. 654 - 656, http://dx.doi.org/10.1038/s41586-021-04387-1

Cromer D; Steain M; Reynaldi A; Schlub TE; Wheatley AK; Juno JA; Kent SJ; Triccas JA; Khoury DS; Davenport MP, 2022, 'Neutralising antibody titres as predictors of protection against SARS-CoV-2 variants and the impact of boosting: a meta-analysis', The Lancet Microbe, 3, pp. e52 - e61, http://dx.doi.org/10.1016/S2666-5247(21)00267-6

Goel RR; Painter MM; Apostolidis SA; Mathew D; Meng W; Rosenfeld AM; Lundgreen KA; Reynaldi A; Khoury DS; Pattekar A; Gouma S; Kuri-Cervantes L; Hicks P; Dysinger S; Hicks A; Sharma H; Herring S; Korte S; Baxter AE; Oldridge DA; Giles JR; Weirick ME; McAllister CM; Awofolaju M; Tanenbaum N; Drapeau EM; Dougherty J; Long S; D’Andrea K; Hamilton JT; McLaughlin M; Williams JC; Adamski S; Kuthuru O; Frank I; Betts MR; Vella LA; Grifoni A; Weiskopf D; Sette A; Hensley SE; Davenport MP; Bates P; Luning Prak ET; Greenplate AR; John Wherry E, 2021, 'mRNA vaccines induce durable immune memory to SARS-CoV-2 and variants of concern', Science, 374, http://dx.doi.org/10.1126/science.abm0829

Wheatley AK; Juno JA; Wang JJ; Selva KJ; Reynaldi A; Tan HX; Lee WS; Wragg KM; Kelly HG; Esterbauer R; Davis SK; Kent HE; Mordant FL; Schlub TE; Gordon DL; Khoury DS; Subbarao K; Cromer D; Gordon TP; Chung AW; Davenport MP; Kent SJ, 2021, 'Evolution of immune responses to SARS-CoV-2 in mild-moderate COVID-19', Nature Communications, 12, http://dx.doi.org/10.1038/s41467-021-21444-5

Rebelo M; McCarthy JS; Khoury DS, 2021, 'Reply to White and Watson.', J Infect Dis, 224, pp. 739 - 740, http://dx.doi.org/10.1093/infdis/jiaa791

Rebelo M; McCarthy JS; Khoury DS, 2021, 'Reply to White and Watson', Journal of Infectious Diseases, 224, pp. 739 - 740, http://dx.doi.org/10.1093/infdis/jiaa791

Khoury DS; Cromer D; Reynaldi A; Schlub TE; Wheatley AK; Juno JA; Subbarao K; Kent SJ; Triccas JA; Davenport MP, 2021, 'Neutralizing antibody levels are highly predictive of immune protection from symptomatic SARS-CoV-2 infection', Nature Medicine, 27, pp. 1205 - 1211, http://dx.doi.org/10.1038/s41591-021-01377-8

Rebelo M; Pawliw R; Gower J; Webb L; Mitchell H; Pava Z; Watts RE; Davenport MP; McCarthy JS; Khoury DS, 2021, 'Parasite Viability as a Superior Measure of Antimalarial Drug Activity in Humans', Journal of Infectious Diseases, 223, pp. 2154 - 2163, http://dx.doi.org/10.1093/infdis/jiaa678

Cromer D; Juno JA; Khoury D; Reynaldi A; Wheatley AK; Kent SJ; Davenport MP, 2021, 'Prospects for durable immune control of SARS-CoV-2 and prevention of reinfection', Nature Reviews Immunology, 21, pp. 395 - 404, http://dx.doi.org/10.1038/s41577-021-00550-x

Cromer D; Reynaldi A; Steain M; Triccas J; Davenport M; Khoury D, 2021, 'Relating in vitro neutralisation level and protection in the CVnCoV (CUREVAC) trial', , http://dx.doi.org/10.1101/2021.06.29.21259504

Cromer D; Steain M; Reynaldi A; Schlub T; Wheatley A; Juno J; Kent S; Triccas J; Khoury D; Davenport M, 2021, 'SARS-CoV-2 variants: levels of neutralisation required for protective immunity', , http://dx.doi.org/10.1101/2021.08.11.21261876

Khoury D; Cromer D; Reynaldi A; Schlub T; Wheatley A; Juno J; Subbarao K; Kent S; Triccas J; Davenport M, 2021, 'What level of neutralising antibody protects from COVID-19?', , http://dx.doi.org/10.1101/2021.03.09.21252641

Khoury DS; Wheatley AK; Ramuta MD; Reynaldi A; Cromer D; Subbarao K; O’Connor DH; Kent SJ; Davenport MP, 2020, 'Measuring immunity to SARS-CoV-2 infection: comparing assays and animal models', Nature Reviews Immunology, 20, pp. 727 - 738, http://dx.doi.org/10.1038/s41577-020-00471-1

Soon MSF; Lee HJ; Engel JA; Straube J; Thomas BS; Pernold CPS; Clarke LS; Laohamonthonkul P; Haldar RN; Williams CG; Lansink LIM; Moreira ML; Bramhall M; Koufariotis LT; Wood S; Chen X; James KR; Lönnberg T; Lane SW; Belz GT; Engwerda CR; Khoury DS; Davenport MP; Svensson V; Teichmann SA; Haque A, 2020, 'Transcriptome dynamics of CD4⁺ T cells during malaria maps gradual transit from effector to memory', Nature Immunology, 21, pp. 1597 - 1610, http://dx.doi.org/10.1038/s41590-020-0800-8

Khoury DS; Cao P; Zaloumis SG; Davenport MP, 2020, 'Artemisinin Resistance and the Unique Selection Pressure of a Short-acting Antimalarial', Trends in Parasitology, 36, pp. 884 - 887, http://dx.doi.org/10.1016/j.pt.2020.07.004

Corder RM; de Lima ACP; Khoury DS; Docken SS; Davenport MP; Ferreira MU, 2020, 'Quantifying and preventing plasmodium vivax recurrences in primaquine-untreated pregnant women: An observational and modeling study in Brazil', PLoS Neglected Tropical Diseases, 14, pp. 1 - 16, http://dx.doi.org/10.1371/journal.pntd.0008526

Collins KA; Wang CYT; Adams M; Mitchell H; Robinson GJ; Rampton M; Elliott S; Odedra A; Khoury D; Ballard E; Shelper TB; Lucantoni L; Avery VM; Chalon S; Moehrle JJ; McCarthy JS, 2020, 'A Plasmodium vivax experimental human infection model for evaluating efficacy of interventions', Journal of Clinical Investigation, 130, pp. 2920 - 2927, http://dx.doi.org/10.1172/JCI134923

Khoury DS; Zaloumis SG; Grigg MJ; Haque A; Davenport MP; Cromer D; Rebelo M; Cao P; McCaw JM; Simpson JA; Flegg JA; Wilson DW; Anstey NM; McCarthy JS, 2020, 'Malaria Parasite Clearance: What Are We Really Measuring?', Trends in Parasitology, 36, pp. 413 - 426, http://dx.doi.org/10.1016/j.pt.2020.02.005

Khoury DS; Cromer D; Möhrle JJ; McCarthy JS; Davenport MP, 2019, 'Corrigendum: Defining the effectiveness of antimalarial chemotherapy: Investigation of the lag in parasite clearance following drug administration (Journal of Infectious Diseases (2016) 214 (753-761) DOI: 10.1093/infdis/jiw234)', Journal of Infectious Diseases, 219, pp. 1852 - 1853, http://dx.doi.org/10.1093/infdis/jiy729

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