Researcher

Dr Jackie Tan-Showyin

Keywords

SEO tags

Biography

Dr Jackie Tan-Showyin is Director of the Eye Research Group at the School of Optometry and Vision Science, UNSW Sydney, leading a passionate team conducting industry sponsored clinical trial research and investigator-initiated trials. Consistently delivering quality research and investing in building long term relationships with industry partners has resulted in collaboration with over 20 multinational industry partners. Her research focuses...view more

Dr Jackie Tan-Showyin is Director of the Eye Research Group at the School of Optometry and Vision Science, UNSW Sydney, leading a passionate team conducting industry sponsored clinical trial research and investigator-initiated trials. Consistently delivering quality research and investing in building long term relationships with industry partners has resulted in collaboration with over 20 multinational industry partners. Her research focuses on dry eye, amongst the general population and in contact lens wearers, and contact lens design and performance. Her research has contributed to the development and subsequent approval of several new dry eye therapies and contacts lens designs over the course of her career. She also supervises PhD students and Masters of Optometry research projects, is a Fellow of the British Contact Lens Association, and a member of the Editorial Board for the journal Eye and Contact Lens.

Click here for more information on the Eye Research Group and Research Topics & Potential Supervisors


My Grants

  • Changes in corneal epithelial irregularity following treatment with artificial tears in a symptomatic dry eye population: $261,067
  • Comparison of the DNEye® Scanner 2 and the IOLMaster 700 for axial length measurement in children: $125,998
  • A randomised, placebo-controlled, double-masked, multicenter, dose-ranging study to evaluate the safety, and efficacy of UNR844 in subjects with presbyopia: ~$249,010
  • A 52 week randomised, single-masked, multicenter proof of concept study of binocular videogames versus patching for amblyopia in children 4-7 years of age with an open-label substudy of binocular videogames in children 8-12 years of age: ~$14,000
  • A Randomised, Double-Masked Vehicle-Controlled, Multiple Dose, Dose Escalation Study to Evaluate the Safety and Tolerability of EXN407 in subjects with Centre Involved Diabetic Macular Oedema secondary to Diabetes Mellitus: ~$6,050
  • Measurement of eye drop retention time using a fluorophotometer: $207,655
  • A randomised, double masked, cross-over clinical trial to compare the vision performance of spectacles prescribed to 0.05D versus 0.25D steps: $142,075
  • A Multicenter, Vehicle-controlled, Randomised Study to Evaluate the Safety, Tolerability and Pharmacodynamics of AZR-MD-001 in Patients with Meibomian Gland Dysfunction (MGD): $74,842
  • A single-centre, vehicle-controlled study to evaluate methods to enhance the safety and tolerability of AZR-MD-001 for meibomian gland dysfunction (MGD): $317,292
  • A double-masked, randomised study of topical pilocarpine administered by the AcuStream delivery system in subjects with age-related presbyopia: $72,355
  • Developing evidence-based guidance for the treatment of dry eye disease (DED) with Systane artificial tear supplements: $123,546
  • A single-center, vehicle-controlled study to evaluate the safety, tolerability and pharmacodynamics of AZR-MD-001 as adjunctive therapy to conventional therapeutic treatment for meibomian gland dysfunction (MGD) : $309,390
  • A phase 2, multicenter, randomised, double-masked, placebo-controlled study to evaluate the clinical safety and efficacy of OKG-0301 in the treatment of acute adenoviral conjunctivitis (RUBY): $9,185
  • The effect of Systane Complete versus saline on tear film properties in a symptomatic dry eye population: $156,753
  • The effect of Systane Complete and Systane Hydration on subjective comfort, vision and satisfaction with mini-scleral contact lens wear: $189,495
  • A Multicenter, Vehicle-controlled, Randomised Study to Evaluate the Safety, Tolerability, Systemic Pharmacokinetics, and Pharmacodynamics in MGD: $403,933
  • Microbial contamination rates on the back surface of soft contact lenses in short-term, randomised, contralateral non-dispensing studies: $164,502
  • Clinical evaluation following use of SYSTANE BALANCE in subjects with lipid-deficient dry eye: $79,780
  • A two comparator, controlled phase 3 study of OM3 Tear formulation versus OPTIVE ADVANCED Unit Dose: $465,040
  • The effects of dietary supplementation with a combination of flaxseed oil, borage oil and fish oil omega-3 fatty acids on ocular comfort including symptoms of dry eye: $127,980
  • Pilot study on the effect of daily disposable silicone hydrogel contact lenses on tear film: $189,822
  • The role of tear lipids in differentiating symptomatic and asymptomatic contact lens wearers – clinical study: $112,352
  • Clinical evaluation following use of SYSTANE ULTRA in the management of dry eye: $54,700
  • A multicentre, double-masked, randomised study to compare the safety and efficacy of 2 OM3 formulations with REFRESH OPTIVE ADVANCED unit dose for 3 months in patients with dry eye disease: $173,953
  • A 3 month dispensing study of First Care cleaning and disinfecting solution in daily wear frequent replacement soft contact lens wearers: $89,284
  • A multicentre, double-masked, randomised study to compare the safety and efficacy of an investigational eye drop formulation with OPTIVE unit-dose for 3 months in subjects with dry eye disease: $169,371

My Qualifications

  • PhD in Optometry (University of New South Wales, 2006)
  • BOptom (Hons) (University of New South Wales, 1994)
  • Graduate Certificate in Ocular Therapeutics (University of New South Wales, 2015)

My Research Activities

Research:

Director, Eye Research Group at the School of Optometry and Vision Science, UNSW Sydney.

Current research trials include:

  • Changes in corneal epithelial irregularity following treatment with artificial tears in a symptomatic dry eye population
  • Comparison of the DNEye Scanner 2 and the IOLMaster 700 for axial length measurement in children
  • A randomised, placebo-controlled, double-masked, multicenter, dose-ranging study to evaluate the safety and efficacy of UNR844 in subjects with presbyopia
  • A randomised, double-masked vehicle-controlled, multiple dose, dose escalation study to evaluate the safety and tolerability of EXN407 in subjects with centre involved diabetic macular oedema secondary to diabetes mellitus
  • Measurement of eye drop retention time using a fluorophotometer
  • A multicenter, vehicle-controlled, randomised study to evaluate the safety, tolerability, systemic pharmacokinetcis, and pharmacodynamics in meibomian gland dysfunction

Teaching:

Supervision of Post-graduate and Honours Optometry students at UNSW.

Current projects include:

  • Longitudinal changes in meibomian gland morphology
  • Effect of eyelid wipes with Manuka honey on ocular signs and symptoms
  • Effect of Optimel Manuka+ Dry Eye Drops with adjunctive treatment on signs and symptoms of dry eye
  • Automatic diagnosis of dry eye disease
  • Predict contact lens discomfort with meibomian gland images

My Research Supervision


Supervision keywords


Areas of supervision

  • Ocular surface including dry eye disease and meibomian gland dysfunction
  • Contact lenses including lens design and risk factors for lens-related complications

Currently supervising

  • Longitudinal changes in meibomian gland morphology
  • Effect of eyelid wipes with Manuka honey on ocular signs and symptoms
  • Effect of Optimel Manuka+ Dry Eye Drops with adjunctive treatment on signs and symptoms of dry eye
  • Automatic diagnosis of dry eye disease
  • Predict contact lens discomfort with meibomian gland images

My Teaching

OPTM8514 Research Project

  • Effect of eyelid wipes with Manuka honey on ocular signs and symptoms
  • Effect of Optimel Manuka+ Dry Eye Drops with adjunctive treatment on signs and symptoms of dry eye
  • Automatic diagnosis of dry eye disease
  • Predict contact lens discomfort with meibomian gland images
View less

Location

School of Optometry & Vision Science
University of New South Wales
Level 3, North Wing, Rupert Myers Building
Gate 14, Barker St
UNSW Sydney NSW 2052
Australia


Contact

+61 2 9385 6551