Select Publications
Book Chapters
2017, 'Molecular Mechanisms Regulating Tooth Number', in Interface Oral Health Science 2016, Springer Singapore, pp. 147 - 162, http://dx.doi.org/10.1007/978-981-10-1560-1_13
,Journal articles
2023, 'Gene expression of male pathway genes sox9 and amh during early sex differentiation in a reptile departs from the classical amniote model', BMC Genomics, 24, http://dx.doi.org/10.1186/s12864-023-09334-0
,2023, 'Improving sarcoma classification by using RNA hybridisation capture sequencing in sarcomas of uncertain histogenesis of young individuals', Pathology, 55, pp. 478 - 485, http://dx.doi.org/10.1016/j.pathol.2022.11.012
,2023, 'Synonymous alterations of cancer-associated Trp53 CpG mutational hotspots cause fatal developmental jaw malocclusions but no tumors in knock-in mice', PLoS ONE, 18, http://dx.doi.org/10.1371/journal.pone.0284327
,2022, 'The retroelement Lx9 puts a brake on the immune response to virus infection', Nature, 608, pp. 757 - 765, http://dx.doi.org/10.1038/s41586-022-05054-9
,2022, 'Standardized practices for RNA diagnostics using clinically accessible specimens reclassifies 75% of putative splicing variants', Genetics in Medicine, 24, pp. 130 - 145, http://dx.doi.org/10.1016/j.gim.2021.09.001
,2021, 'Cross-oncopanel study reveals high sensitivity and accuracy with overall analytical performance depending on genomic regions', Genome Biology, 22, pp. 109, http://dx.doi.org/10.1186/s13059-021-02315-0
,2021, 'Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology', Nature Biotechnology, 39, pp. 1115 - 1128, http://dx.doi.org/10.1038/s41587-021-00857-z
,2021, 'Two transcriptionally distinct pathways drive female development in a reptile with both genetic and temperature dependent sex determination', PLoS Genetics, 17, http://dx.doi.org/10.1371/journal.pgen.1009465
,2021, 'Two transcriptionally distinct pathways drive female development in a reptile with both genetic and temperature dependent sex determination', , http://dx.doi.org/10.1101/2021.02.03.429474
,2020, 'A universal and independent synthetic DNA ladder for the quantitative measurement of genomic features', Nature Communications, 11, http://dx.doi.org/10.1038/s41467-020-17445-5
,2020, 'Author Correction: Diagnosis of fusion genes using targeted RNA sequencing (Nature Communications, (2019), 10, 1, (1388), 10.1038/s41467-019-09374-9)', Nature Communications, 11, pp. 1810, http://dx.doi.org/10.1038/s41467-020-15697-9
,2020, 'Molecular patterns in salivary duct carcinoma identify prognostic subgroups', Modern Pathology, 33, pp. 1896 - 1909, http://dx.doi.org/10.1038/s41379-020-0576-2
,2020, 'Overactivation of the NF-κB pathway impairs molar enamel formation', Oral Diseases, 26, pp. 1513 - 1522, http://dx.doi.org/10.1111/odi.13384
,2020, 'Sequencing Strategies for Fusion Gene Detection', BioEssays, 42, http://dx.doi.org/10.1002/bies.202000016
,2020, 'Lymphoma Driver Mutations in the Pathogenic Evolution of an Iconic Human Autoantibody', Cell, 180, pp. 878 - 894.e19, http://dx.doi.org/10.1016/j.cell.2020.01.029
,2019, 'Chiral DNA sequences as commutable controls for clinical genomics', Nature Communications, 10, http://dx.doi.org/10.1038/s41467-019-09272-0
,2019, 'Diagnosis of fusion genes using targeted RNA sequencing', Nature Communications, 10, pp. 1388, http://dx.doi.org/10.1038/s41467-019-09374-9
,2019, 'High-throughput targeted long-read single cell sequencing reveals the clonal and transcriptional landscape of lymphocytes', Nature Communications, 10, http://dx.doi.org/10.1038/s41467-019-11049-4
,2019, 'TMPRSS2-ERG fusions linked to prostate cancer racial health disparities: A focus on Africa', Prostate, 79, pp. 1191 - 1196, http://dx.doi.org/10.1002/pros.23823
,2019, 'Use of synthetic DNA spike-in controls (sequins) for human genome sequencing', Nature Protocols, 14, pp. 2119 - 2151, http://dx.doi.org/10.1038/s41596-019-0175-1
,2019, 'MicroRNAs control eyelid development through regulating Wnt signaling', Developmental Dynamics, 248, pp. 201 - 210, http://dx.doi.org/10.1002/dvdy.10
,2019, 'Crizotinib and surgery for long-term disease control in children and adolescents with ALK-positive inflammatory myofibroblastic tumors', JCO Precision Oncology, 3, pp. 1 - 11, http://dx.doi.org/10.1200/PO.18.00297
,2019, 'Targeted, high-resolution RNA sequencing of non-coding genomic regions associated with neuropsychiatric functions', Frontiers in Genetics, 10, pp. 309, http://dx.doi.org/10.3389/fgene.2019.00309
,2019, 'The targetable genomic landscape of salivary duct carcinoma', Pathology, 51, pp. S83 - S83, http://dx.doi.org/10.1016/j.pathol.2018.12.210
,2018, 'Lrp4/Wise regulates palatal rugae development through turing-type reaction-diffusion mechanisms', PLoS ONE, 13, http://dx.doi.org/10.1371/journal.pone.0204126
,2018, 'Chiral DNA sequences as commutable reference standards for clinical genomics', BIORXIV, http://dx.doi.org/10.1101/404285
,2018, 'Universal Alternative Splicing of Noncoding Exons', Cell Systems, 6, pp. 245 - 255.e5, http://dx.doi.org/10.1016/j.cels.2017.12.005
,2018, 'High-throughput targeted long-read single cell sequencing reveals the clonal and transcriptional landscape of lymphocytes', , http://dx.doi.org/10.1101/424945
,2017, 'Phosphoproteomic profiling reveals ALK and MET as novel actionable targets across synovial sarcoma subtypes', Cancer Research, 77, pp. 4279 - 4292, http://dx.doi.org/10.1158/0008-5472.CAN-16-2550
,2017, 'Differential intron retention in Jumonji chromatin modifier genes is implicated in reptile temperature-dependent sex determination', Science Advances, 3, pp. e1700731, http://dx.doi.org/10.1126/sciadv.1700731
,2016, 'Damage-inducible intragenic demethylation of the human TP53 tumor suppressor gene is associated with transcription from an alternative intronic promoter', Molecular Carcinogenesis, 55, pp. 1940 - 1951, http://dx.doi.org/10.1002/mc.22441
,2016, 'Regional regulation of Filiform tongue papillae development by Ikkα/Irf6', Developmental Dynamics, 245, pp. 937 - 946, http://dx.doi.org/10.1002/dvdy.24427
,2016, 'Spliced synthetic genes as internal controls in RNA sequencing experiments', Nature Methods, 13, pp. 792 - 798, http://dx.doi.org/10.1038/nmeth.3958
,2016, 'Spatio-temporal expression of Sox genes in murine palatogenesis', Gene Expression Patterns, 21, pp. 111 - 118, http://dx.doi.org/10.1016/j.gep.2016.05.002
,2015, 'Excess NF-κB induces ectopic odontogenesis in embryonic incisor epithelium', Journal of Dental Research, 94, pp. 121 - 128, http://dx.doi.org/10.1177/0022034514556707
,2012, 'Bmp signalling in filiform tongue papillae development', Archives of Oral Biology, 57, pp. 805 - 813, http://dx.doi.org/10.1016/j.archoralbio.2011.11.014
,2012, 'The role of Irf6 in tooth epithelial invagination', Developmental Biology, 365, pp. 61 - 70, http://dx.doi.org/10.1016/j.ydbio.2012.02.009
,2010, 'A role for suppressed incisor cuspal morphogenesis in the evolution of mammalian heterodont dentition', Proceedings of the National Academy of Sciences of the United States of America, 107, pp. 92 - 97, http://dx.doi.org/10.1073/pnas.0907236107
,2009, 'Primary cilia regulate Shh activity in the control of molar tooth number', Development, 136, pp. 897 - 903, http://dx.doi.org/10.1242/dev.027979
,2006, 'CD 95 mediated apoptosis in embryogenesis: Implication in tooth development', Orthodontics and Craniofacial Research, 9, pp. 123 - 128, http://dx.doi.org/10.1111/j.1601-6343.2006.00365.x
,2005, 'The Ectodysplasin and NFκB signalling pathways in odontogenesis', Archives of Oral Biology, 50, pp. 159 - 163, http://dx.doi.org/10.1016/j.archoralbio.2004.11.019
,2003, 'Transcriptional Regulation and Expression of the Dominant Drusen Gene FBLN3 (EFEMP1) in Mammalian Retina', Investigative Ophthalmology and Visual Science, 44, pp. 4613 - 4621, http://dx.doi.org/10.1167/iovs.03-0112
,2001, 'Molecular genetic heterogeneity in autosomal dominant drusen', Journal of Medical Genetics, 38, pp. 381 - 384, http://dx.doi.org/10.1136/jmg.38.6.381
,Conference Presentations
2014, 'Damage-inducible intragenic demethylation activates transcription of an alternative intronic promoter in TP53-wildtype but not mutant human cells and tumors', presented at 105th Annual Meeting of the American-Association-for-Cancer-Research (AACR), CA, San Diego, 05 April 2014 - 09 April 2014, http://dx.doi.org/10.1158/1538-7445.AM2014-LB-85
,Conference Abstracts
2022, 'Molecular therapy selection in treatment-refractory advanced cancers: A retrospective cohort study determining the utility of TOPOGRAPH knowledge base.', in JOURNAL OF CLINICAL ONCOLOGY, LIPPINCOTT WILLIAMS & WILKINS, ELECTR NETWORK, Vol. 40, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), ELECTR NETWORK, 03 June 2022 - 07 June 2022, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000863680300966&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2022, 'Molecular therapy selection in treatment-refractory advanced cancers: A retrospective cohort study determining the utility of TOPOGRAPH knowledge base.', in Journal of Clinical Oncology, American Society of Clinical Oncology (ASCO), Vol. 40, pp. 3073 - 3073, http://dx.doi.org/10.1200/jco.2022.40.16_suppl.3073
,2021, 'Molecular patterns in salivary duct carcinoma identify prognostic subgroups', in ORAL ONCOLOGY, ELSEVIER, Vol. 118, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000669389300007&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2019, 'Abstract 4824: Targeting CD30 as a novel treatment strategy inRANBP2-ALK-rearranged inflammatory myofibroblastic tumor', in Experimental and Molecular Therapeutics, American Association for Cancer Research, presented at Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA, http://dx.doi.org/10.1158/1538-7445.sabcs18-4824
,2019, 'Targeting CD30 as a novel treatment strategy in RANBP2-ALK-rearranged inflammatory myofibroblastic tumor', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, GA, Atlanta, Vol. 79, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), GA, Atlanta, 29 March 2019 - 03 April 2019, http://dx.doi.org/10.1158/1538-7445.AM2019-4824
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