Select Publications

Journal articles

Yoffe A; Liu J; Smith G; Chisholm O, 2023, 'A Survey of Industry Perceptions of Facilitated Regulatory Pathways in Drug Development in Australia', Pharmaceutical Medicine, 37, pp. 385 - 394, http://dx.doi.org/10.1007/s40290-023-00483-x

Cui H; Luo X; Chen M; Lu J; Liu JJ, 2023, 'Investigational Agents Targeting SGLT1 and SGLT2 in the Treatment of Type 2 Diabetes Mellitus', Current Drug Targets, 24, pp. 648 - 661, http://dx.doi.org/10.2174/1389450124666230503120930

Yoffe A; Liu J; Smith G; Chisholm O, 2023, 'Regulatory Reform Outcomes and Accelerated Regulatory Pathways for New Prescription Medicines in Australia', Therapeutic Innovation and Regulatory Science, 57, pp. 271 - 286, http://dx.doi.org/10.1007/s43441-022-00465-2

Yang T; Li M; Li H; Shi P; Liu J; Chen M, 2020, 'Downregulation of circEPSTI1 represses the proliferation and invasion of non-small cell lung cancer by inhibiting TRIM24 via miR-1248 upregulation', Biochemical and Biophysical Research Communications, 530, pp. 348 - 354, http://dx.doi.org/10.1016/j.bbrc.2020.06.106

Zhang PP; Li LL; Han X; Li QW; Zhang XH; Liu JJ; Wang Y, 2020, 'Fecal microbiota transplantation improves metabolism and gut microbiome composition in db/db mice', Acta Pharmacologica Sinica, 41, pp. 678 - 685, http://dx.doi.org/10.1038/s41401-019-0330-9

Myint K; Biswas R; Li Y; Jong N; Jamieson S; Liu J; Han C; Squire C; Merien F; Lu J; Nakanishi T; Tamai I; McKeage M, 2019, 'Identification of MRP2 as a targetable factor limiting oxaliplatin accumulation and response in gastrointestinal cancer', Scientific Reports, 9, http://dx.doi.org/10.1038/s41598-019-38667-8

Lin J; Xu Y; Wang Y; Huang S; Li J; Meti MD; Xu X; Hu Z; Liu J; He Z; Xu H, 2019, 'Dissection of binding of trypsin to its natural inhibitor Gensenoside-Rg1 using spectroscopic methods and molecular modeling', Journal of Biomolecular Structure and Dynamics, 37, pp. 4070 - 4079, http://dx.doi.org/10.1080/07391102.2018.1539411

Biswas R; Bugde P; He J; Merien F; Lu J; Liu DX; Myint K; Liu J; McKeage M; Li Y, 2019, 'Transport-mediated oxaliplatin resistance associated with endogenous overexpression of MRP2 in Caco-2 and PANC-1 Cells', Cancers, 11, http://dx.doi.org/10.3390/cancers11091330

Meti MD; Xu Y; Xie J; Chen Y; Wu Z; Liu J; Han Q; He Z; Hu Z; Xu H, 2018, 'Multi-spectroscopic studies on the interaction between traditional Chinese herb, helicid with pepsin', Molecular Biology Reports, 45, pp. 1637 - 1646, http://dx.doi.org/10.1007/s11033-018-4306-5

Cui H; Zhang AJ; McKeage MJ; Nott LM; Geraghty D; Guven N; Liu JJ, 2017, 'Copper transporter 1 in human colorectal cancer cell lines: Effects of endogenous and modified expression on oxaliplatin cytotoxicity', Journal of Inorganic Biochemistry, 177, pp. 249 - 258, http://dx.doi.org/10.1016/j.jinorgbio.2017.04.022

Zhang S; Gao L; Thakur A; Shi P; Liu F; Feng J; Wang T; Liang Y; Liu JJ; Chen M; Ren H, 2016, 'miRNA-204 suppresses human non-small cell lung cancer by targeting ATF2', Tumor Biology, 37, pp. 11177 - 11186, http://dx.doi.org/10.1007/s13277-016-4906-4

Ren H; Guo H; Thakur A; Zhang S; Wang T; Liang Y; Shi P; Gao L; Liu F; Feng J; Chen T; Yang T; Shang D; Liu JJ; Xu F; Chen M, 2016, 'Blockade efficacy of MEK/ERK-dependent autophagy enhances PI3K/Akt inhibitor NVP-BKM120's therapeutic effectiveness in lung cancer cells', Oncotarget, 7, pp. 67277 - 67287, http://dx.doi.org/10.18632/oncotarget.11645

Yan F; Liu JJ; Ip V; Jamieson SMF; McKeage MJ, 2015, 'Role of platinum DNA damage-induced transcriptional inhibition in chemotherapy-induced neuronal atrophy and peripheral neurotoxicity', Journal of Neurochemistry, 135, pp. 1099 - 1112, http://dx.doi.org/10.1111/jnc.13355

Qian Z; Wu Z; Huang L; Qiu H; Wang L; Li L; Yao L; Kang K; Qu J; Wu Y; Luo J; Liu JJ; Yang Y; Yang W; Gou D, 2015, 'Mulberry fruit prevents LPS-induced NF-κB/pERK/MAPK signals in macrophages and suppresses acute colitis and colorectal tumorigenesis in mice', Scientific Reports, 5, http://dx.doi.org/10.1038/srep17348

Cui H; Zhang AJ; Chen M; Liu JJ, 2015, 'ABC transporter inhibitors in reversing multidrug resistance to chemotherapy', Current Drug Targets, 16, pp. 1356 - 1371, http://dx.doi.org/10.2174/1389450116666150330113506

Wang T; Chen T; Thakur A; Liang Y; Gao L; Zhang S; Tian Y; Jin T; Liu JJ; Chen M, 2015, 'Association of PSMA4 polymorphisms with lung cancer susceptibility and response to cisplatin-based chemotherapy in a Chinese Han population', Clinical and Translational Oncology, 17, pp. 564 - 569, http://dx.doi.org/10.1007/s12094-015-1279-x

Zhang S; Thakur A; Liang Y; Wang T; Gao L; Yang T; Li Y; Geng T; Jin T; Chen T; Liu JJ; Chen M, 2015, 'Polymorphisms in C-reactive protein and glypican-5 are associated with lung cancer risk and gartrokine-1 influences cisplatin-based chemotherapy response in a Chinese Han population', Disease Markers, 2015, http://dx.doi.org/10.1155/2015/824304

Yan F; Liu JJ; Ip V; Jamieson SMF; Mckeage MJ, 2015, 'Role of platinum DNA damage-induced transcriptional inhibition in chemotherapy-induced neuronal atrophy and peripheral neurotoxicity', Journal of Neurochemistry, http://dx.doi.org/10.1111/jnc.13355

Dai SY; Liu JJ; Sun XF; Wang N, 2015, 'Acid sphingomyelinase, a novel negative biomarker of ovarian cancer.', Eur Rev Med Pharmacol Sci, 19, pp. 2076 - 2083, https://www.ncbi.nlm.nih.gov/pubmed/26125272

Chen M LJJ, 2015, 'Systems Pharmacology for the Study of Anticancer Drugs: Promises and Challenges', Clinical Pharmacology & Biopharmaceutics, 04, http://dx.doi.org/10.4172/2167-065x.1000140

Gao L; Thakur A; Liang Y; Zhang S; Wang T; Chen T; Meng J; Wang L; Wu F; Jin T; Li X; Liu JJ; Chen C; Chen M, 2014, 'Polymorphisms in the TERT gene are associated with lung cancer risk in the Chinese Han population', European Journal of Cancer Prevention, 23, pp. 497 - 501, http://dx.doi.org/10.1097/CEJ.0000000000000086

Ip V; Liu JJ; Mckeage MJ, 2013, 'Evaluation of effects of copper histidine on copper transporter 1-mediated accumulation of platinum and oxaliplatin-induced neurotoxicity in vitro and in vivo', Clinical and Experimental Pharmacology and Physiology, 40, pp. 371 - 378, http://dx.doi.org/10.1111/1440-1681.12088

Liu JJ; Kim Y; Yan F; Ding Q; Ip V; Jong NN; Mercer JFB; McKeage MJ, 2013, 'Contributions of rat Ctr1 to the uptake and toxicity of copper and platinum anticancer drugs in dorsal root ganglion neurons', Biochemical Pharmacology, 85, pp. 207 - 215, http://dx.doi.org/10.1016/j.bcp.2012.10.023

Liu JJ; Lu J; McKeage MJ, 2012, 'Membrane transporters as determinants of the pharmacology of platinum anticancer drugs', Current Cancer Drug Targets, 12, pp. 962 - 986, http://dx.doi.org/10.2174/156800912803251199

Jong NN; Nakanishi T; Liu JJ; Tamai I; McKeage MJ, 2011, 'Oxaliplatin transport mediated by organic cation/carnitine transporters OCTN1 and OCTN2 in overexpressing human embryonic kidney 293 cells and rat dorsal root ganglion neurons', Journal of Pharmacology and Experimental Therapeutics, 338, pp. 537 - 547, http://dx.doi.org/10.1124/jpet.111.181297

Liu JJ; Kim Y; Mercer JFB; McKeage MJ, 2011, 'Copper and platinum uptake in cultured rat dorsal root ganglion neurons', CANCER RESEARCH, 71, http://dx.doi.org/10.1158/1538-7445.AM2011-4389

Jong NN; Nakanishi T; Liu JJ; Tamai I; McKeage MJ, 2011, 'OCTN1-and OCTN2-mediated uptake of oxaliplatin in rat dorsal root ganglion neurons and HEK293 cells over-expressing OCTN1 or OCTN2', CANCER RESEARCH, 71, http://dx.doi.org/10.1158/1538-7445.AM2011-4391

Zhang J; Zhang XB; Liu JJ; Mao QX; Ma Y; Zhang S, 2010, 'Abstract PD02-09: Effects of an mTOR Inhibitor RAD001 on Human Breast Cancer Stem Cells In Vitro', Cancer Research, 70, http://dx.doi.org/10.1158/0008-5472.sabcs10-pd02-09

Ip V; Liu J; Mercer J; McKeage M, 2010, 'DIFFERENTIAL EXPRESSION OF COPPER EFFLUX AND INFLUX TRANSPORTERS IN RAT DRG TISSUE MAY INFLUENCE OXALIPLATIN NEUROTOXICITY', , pp. 167 - 167, http://dx.doi.org/10.14896/jssxmeeting.25.0.167.0

Jong NN; Liu JJ; McKeage MJ; Nakanishi T; Tamai I, 2010, 'DIFFERENTIAL EXPRESSION OF ORGANIC CATION TRANSPORTERS IN RAT DORSAL ROOT GANGLIA', , pp. 50 - 50, http://dx.doi.org/10.14896/jssxmeeting.25.0.50.0

Ip V; Liu JJ; Mercer JFB; McKeage MJ, 2010, 'Differential expression of ATP7A, ATP7B and CTR1 in adult rat dorsal root ganglion tissue', Molecular Pain, 6, http://dx.doi.org/10.1186/1744-8069-6-53

Jamieson SMF; Subramaniam J; Liu JJ; Jong NN; Ip V; Connor B; McKeage MJ, 2009, 'Oxaliplatin-induced loss of phosphorylated heavy neurofilament subunit neuronal immunoreactivity in rat DRG tissue', Molecular Pain, 5, http://dx.doi.org/10.1186/1744-8069-5-66

Liu JJ; Jamieson SMF; Subramaniam J; Ip V; Jong NN; Mercer JFB; McKeage MJ, 2009, 'Neuronal expression of copper transporter 1 in rat dorsal root ganglia: Association with platinum neurotoxicity', Cancer Chemotherapy and Pharmacology, 64, pp. 847 - 856, http://dx.doi.org/10.1007/s00280-009-1017-6

Bell DN; Liu JJ; Tingle MD; Rattel B; Meyer TU; McKeage MJ, 2008, 'Comparative protein binding, stability and degradation of satraplatin, JM118 and cisplatin in human plasma in vitro', Clinical and Experimental Pharmacology and Physiology, 35, pp. 1440 - 1446, http://dx.doi.org/10.1111/j.1440-1681.2008.05017.x

Ip V; McKeage MJ; Thompson P; Damianovich D; Findlay M; Liu JJ, 2008, 'Platinum-specific detection and quantification of oxaliplatin and Pt(R,R-diaminocyclohexane)Cl2 in the blood plasma of colorectal cancer patients', Journal of Analytical Atomic Spectrometry, 23, pp. 881 - 884, http://dx.doi.org/10.1039/b716925f

Liu JJ; Galettis P; Farr A; Maharaj L; Samarasinha H; McGechan AC; Baguley BC; Bowen RJ; Berners-Price SJ; McKeage MJ, 2008, 'In vitro antitumour and hepatotoxicity profiles of Au(I) and Ag(I) bidentate pyridyl phosphine complexes and relationships to cellular uptake', Journal of Inorganic Biochemistry, 102, pp. 303 - 310, http://dx.doi.org/10.1016/j.jinorgbio.2007.09.003

Chung F; Liu J; Ching L-M; Baguley BC, 2008, 'Consequences of increased vascular permeability induced by treatment of mice with 5,6-dimethylxanthenone-4-acetic acid (DMXAA) and thalidomide.', Cancer Chemother Pharmacol, 61, pp. 497 - 502, http://dx.doi.org/10.1007/s00280-007-0495-7

Jamieson SMF; Liu JJ; Connor B; Dragunow M; McKeage MJ, 2007, 'Nucleolar enlargement, nuclear eccentricity and altered cell body immunostaining characteristics of large-sized sensory neurons following treatment of rats with paclitaxel', NeuroToxicology, 28, pp. 1092 - 1098, http://dx.doi.org/10.1016/j.neuro.2007.04.009

Liu JJ; Ching LM; Goldthorpe M; Sutherland R; Baguley BC; Kirker JA; McKeage MJ, 2007, 'Antitumour action of 5,6-dimethylxanthenone-4-acetic acid in rats bearing chemically induced primary mammary tumours', Cancer Chemotherapy and Pharmacology, 59, pp. 661 - 669, http://dx.doi.org/10.1007/s00280-006-0321-7

Liu JJ; Ching L-M; Goldthorpe M; Sutherland R; Baguley BC; Kirker JA; McKeage MJ, 2006, 'Antitumour action of 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in rats bearing chemically-induced primary mammary tumours', ACTA PHARMACOLOGICA SINICA, 27, pp. 70 - 70, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000239590000413&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Bell DN; Liu JJ; Tingle MD; McKeage MJ, 2006, 'Specific determination of intact cisplatin and monohydrated cisplatin in human plasma and culture medium ultrafiltrates using HPLC on-line with inductively coupled plasma mass spectrometry', Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 837, pp. 29 - 34, http://dx.doi.org/10.1016/j.jchromb.2006.03.063

Jiang HX; Zeng ZL; Chen ZL; Liu JJ; Fung KF, 2006, 'Pharmacokinetics of florfenicol in pigs following intravenous, intramuscular or oral administration and the effects of feed intake on oral dosing', Journal of Veterinary Pharmacology and Therapeutics, 29, pp. 153 - 156, http://dx.doi.org/10.1111/j.1365-2885.2006.00727.x

Jamieson SMF; Liu J; Connor B; McKeage MJ, 2005, 'Oxaliplatin causes selective atrophy of a subpopulation of dorsal root ganglion neurons without inducing cell loss', Cancer Chemotherapy and Pharmacology, 56, pp. 391 - 399, http://dx.doi.org/10.1007/s00280-004-0953-4

Jamieson SMF; Liu J; Hsu T; Baguley BC; McKeage MJ, 2003, 'Paclitaxel induces nucleolar enlargement in dorsal root ganglion neurons in vivo reducing oxaliplatin toxicity', British Journal of Cancer, 88, pp. 1942 - 1947, http://dx.doi.org/10.1038/sj.bjc.6601012

Liu J; Fung KF; Chen Z; Zeng Z; Zhang J, 2003, 'Pharmacokinetics of florfenicol in healthy pigs and in pigs experimentally infected with Actinobacillus pleuropneumoniae', Antimicrobial Agents and Chemotherapy, 47, pp. 820 - 823, http://dx.doi.org/10.1128/AAC.47.2.820-823.2003

Liu JZ; Fung KF; Chen ZL; Zeng ZL; Zhang J, 2002, 'Tissue pharmacokinetics of florfenicol in pigs experimentally infected with Actinobacillus pleuropneumoniae', European Journal of Drug Metabolism and Pharmacokinetics, 27, pp. 265 - 271, http://dx.doi.org/10.1007/BF03192337

Conference Papers

Liu JJ; Kestell P; Findlay M; Riley G; Ackland S; Simpson A; Isaacs R; McKeage MJ, 2004, 'Application of liquid chromatography-mass spectrometry to monitoring plasma cyclophosphamide levels in phase I trial cancer patients', in Clinical and Experimental Pharmacology and Physiology, pp. 677 - 682, http://dx.doi.org/10.1111/j.1440-1681.2004.03065.x


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