Select Publications
Journal articles
2023, 'A Survey of Industry Perceptions of Facilitated Regulatory Pathways in Drug Development in Australia', Pharmaceutical Medicine, 37, pp. 385 - 394, http://dx.doi.org/10.1007/s40290-023-00483-x
,2023, 'Investigational Agents Targeting SGLT1 and SGLT2 in the Treatment of Type 2 Diabetes Mellitus', Current Drug Targets, 24, pp. 648 - 661, http://dx.doi.org/10.2174/1389450124666230503120930
,2023, 'Regulatory Reform Outcomes and Accelerated Regulatory Pathways for New Prescription Medicines in Australia', Therapeutic Innovation and Regulatory Science, 57, pp. 271 - 286, http://dx.doi.org/10.1007/s43441-022-00465-2
,2020, 'Downregulation of circEPSTI1 represses the proliferation and invasion of non-small cell lung cancer by inhibiting TRIM24 via miR-1248 upregulation', Biochemical and Biophysical Research Communications, 530, pp. 348 - 354, http://dx.doi.org/10.1016/j.bbrc.2020.06.106
,2020, 'Fecal microbiota transplantation improves metabolism and gut microbiome composition in db/db mice', Acta Pharmacologica Sinica, 41, pp. 678 - 685, http://dx.doi.org/10.1038/s41401-019-0330-9
,2019, 'Identification of MRP2 as a targetable factor limiting oxaliplatin accumulation and response in gastrointestinal cancer', Scientific Reports, 9, http://dx.doi.org/10.1038/s41598-019-38667-8
,2019, 'Dissection of binding of trypsin to its natural inhibitor Gensenoside-Rg1 using spectroscopic methods and molecular modeling', Journal of Biomolecular Structure and Dynamics, 37, pp. 4070 - 4079, http://dx.doi.org/10.1080/07391102.2018.1539411
,2019, 'Transport-mediated oxaliplatin resistance associated with endogenous overexpression of MRP2 in Caco-2 and PANC-1 Cells', Cancers, 11, http://dx.doi.org/10.3390/cancers11091330
,2018, 'Multi-spectroscopic studies on the interaction between traditional Chinese herb, helicid with pepsin', Molecular Biology Reports, 45, pp. 1637 - 1646, http://dx.doi.org/10.1007/s11033-018-4306-5
,2017, 'Copper transporter 1 in human colorectal cancer cell lines: Effects of endogenous and modified expression on oxaliplatin cytotoxicity', Journal of Inorganic Biochemistry, 177, pp. 249 - 258, http://dx.doi.org/10.1016/j.jinorgbio.2017.04.022
,2016, 'miRNA-204 suppresses human non-small cell lung cancer by targeting ATF2', Tumor Biology, 37, pp. 11177 - 11186, http://dx.doi.org/10.1007/s13277-016-4906-4
,2016, 'Blockade efficacy of MEK/ERK-dependent autophagy enhances PI3K/Akt inhibitor NVP-BKM120's therapeutic effectiveness in lung cancer cells', Oncotarget, 7, pp. 67277 - 67287, http://dx.doi.org/10.18632/oncotarget.11645
,2015, 'Role of platinum DNA damage-induced transcriptional inhibition in chemotherapy-induced neuronal atrophy and peripheral neurotoxicity', Journal of Neurochemistry, 135, pp. 1099 - 1112, http://dx.doi.org/10.1111/jnc.13355
,2015, 'Mulberry fruit prevents LPS-induced NF-κB/pERK/MAPK signals in macrophages and suppresses acute colitis and colorectal tumorigenesis in mice', Scientific Reports, 5, http://dx.doi.org/10.1038/srep17348
,2015, 'ABC transporter inhibitors in reversing multidrug resistance to chemotherapy', Current Drug Targets, 16, pp. 1356 - 1371, http://dx.doi.org/10.2174/1389450116666150330113506
,2015, 'Association of PSMA4 polymorphisms with lung cancer susceptibility and response to cisplatin-based chemotherapy in a Chinese Han population', Clinical and Translational Oncology, 17, pp. 564 - 569, http://dx.doi.org/10.1007/s12094-015-1279-x
,2015, 'Polymorphisms in C-reactive protein and glypican-5 are associated with lung cancer risk and gartrokine-1 influences cisplatin-based chemotherapy response in a Chinese Han population', Disease Markers, 2015, http://dx.doi.org/10.1155/2015/824304
,2015, 'Role of platinum DNA damage-induced transcriptional inhibition in chemotherapy-induced neuronal atrophy and peripheral neurotoxicity', Journal of Neurochemistry, http://dx.doi.org/10.1111/jnc.13355
,2015, 'Acid sphingomyelinase, a novel negative biomarker of ovarian cancer.', Eur Rev Med Pharmacol Sci, 19, pp. 2076 - 2083, https://www.ncbi.nlm.nih.gov/pubmed/26125272
,2015, 'Systems Pharmacology for the Study of Anticancer Drugs: Promises and Challenges', Clinical Pharmacology & Biopharmaceutics, 04, http://dx.doi.org/10.4172/2167-065x.1000140
,2014, 'Polymorphisms in the TERT gene are associated with lung cancer risk in the Chinese Han population', European Journal of Cancer Prevention, 23, pp. 497 - 501, http://dx.doi.org/10.1097/CEJ.0000000000000086
,2013, 'Evaluation of effects of copper histidine on copper transporter 1-mediated accumulation of platinum and oxaliplatin-induced neurotoxicity in vitro and in vivo', Clinical and Experimental Pharmacology and Physiology, 40, pp. 371 - 378, http://dx.doi.org/10.1111/1440-1681.12088
,2013, 'Contributions of rat Ctr1 to the uptake and toxicity of copper and platinum anticancer drugs in dorsal root ganglion neurons', Biochemical Pharmacology, 85, pp. 207 - 215, http://dx.doi.org/10.1016/j.bcp.2012.10.023
,2012, 'Membrane transporters as determinants of the pharmacology of platinum anticancer drugs', Current Cancer Drug Targets, 12, pp. 962 - 986, http://dx.doi.org/10.2174/156800912803251199
,2011, 'Oxaliplatin transport mediated by organic cation/carnitine transporters OCTN1 and OCTN2 in overexpressing human embryonic kidney 293 cells and rat dorsal root ganglion neurons', Journal of Pharmacology and Experimental Therapeutics, 338, pp. 537 - 547, http://dx.doi.org/10.1124/jpet.111.181297
,2011, 'Copper and platinum uptake in cultured rat dorsal root ganglion neurons', CANCER RESEARCH, 71, http://dx.doi.org/10.1158/1538-7445.AM2011-4389
,2011, 'OCTN1-and OCTN2-mediated uptake of oxaliplatin in rat dorsal root ganglion neurons and HEK293 cells over-expressing OCTN1 or OCTN2', CANCER RESEARCH, 71, http://dx.doi.org/10.1158/1538-7445.AM2011-4391
,2010, 'Abstract PD02-09: Effects of an mTOR Inhibitor RAD001 on Human Breast Cancer Stem Cells In Vitro', Cancer Research, 70, http://dx.doi.org/10.1158/0008-5472.sabcs10-pd02-09
,2010, 'DIFFERENTIAL EXPRESSION OF COPPER EFFLUX AND INFLUX TRANSPORTERS IN RAT DRG TISSUE MAY INFLUENCE OXALIPLATIN NEUROTOXICITY', , pp. 167 - 167, http://dx.doi.org/10.14896/jssxmeeting.25.0.167.0
,2010, 'DIFFERENTIAL EXPRESSION OF ORGANIC CATION TRANSPORTERS IN RAT DORSAL ROOT GANGLIA', , pp. 50 - 50, http://dx.doi.org/10.14896/jssxmeeting.25.0.50.0
,2010, 'Differential expression of ATP7A, ATP7B and CTR1 in adult rat dorsal root ganglion tissue', Molecular Pain, 6, http://dx.doi.org/10.1186/1744-8069-6-53
,2009, 'Oxaliplatin-induced loss of phosphorylated heavy neurofilament subunit neuronal immunoreactivity in rat DRG tissue', Molecular Pain, 5, http://dx.doi.org/10.1186/1744-8069-5-66
,2009, 'Neuronal expression of copper transporter 1 in rat dorsal root ganglia: Association with platinum neurotoxicity', Cancer Chemotherapy and Pharmacology, 64, pp. 847 - 856, http://dx.doi.org/10.1007/s00280-009-1017-6
,2008, 'Comparative protein binding, stability and degradation of satraplatin, JM118 and cisplatin in human plasma in vitro', Clinical and Experimental Pharmacology and Physiology, 35, pp. 1440 - 1446, http://dx.doi.org/10.1111/j.1440-1681.2008.05017.x
,2008, 'Platinum-specific detection and quantification of oxaliplatin and Pt(R,R-diaminocyclohexane)Cl
2008, 'In vitro antitumour and hepatotoxicity profiles of Au(I) and Ag(I) bidentate pyridyl phosphine complexes and relationships to cellular uptake', Journal of Inorganic Biochemistry, 102, pp. 303 - 310, http://dx.doi.org/10.1016/j.jinorgbio.2007.09.003
,2008, 'Consequences of increased vascular permeability induced by treatment of mice with 5,6-dimethylxanthenone-4-acetic acid (DMXAA) and thalidomide.', Cancer Chemother Pharmacol, 61, pp. 497 - 502, http://dx.doi.org/10.1007/s00280-007-0495-7
,2007, 'Nucleolar enlargement, nuclear eccentricity and altered cell body immunostaining characteristics of large-sized sensory neurons following treatment of rats with paclitaxel', NeuroToxicology, 28, pp. 1092 - 1098, http://dx.doi.org/10.1016/j.neuro.2007.04.009
,2007, 'Antitumour action of 5,6-dimethylxanthenone-4-acetic acid in rats bearing chemically induced primary mammary tumours', Cancer Chemotherapy and Pharmacology, 59, pp. 661 - 669, http://dx.doi.org/10.1007/s00280-006-0321-7
,2006, 'Antitumour action of 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in rats bearing chemically-induced primary mammary tumours', ACTA PHARMACOLOGICA SINICA, 27, pp. 70 - 70, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000239590000413&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2006, 'Specific determination of intact cisplatin and monohydrated cisplatin in human plasma and culture medium ultrafiltrates using HPLC on-line with inductively coupled plasma mass spectrometry', Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 837, pp. 29 - 34, http://dx.doi.org/10.1016/j.jchromb.2006.03.063
,2006, 'Pharmacokinetics of florfenicol in pigs following intravenous, intramuscular or oral administration and the effects of feed intake on oral dosing', Journal of Veterinary Pharmacology and Therapeutics, 29, pp. 153 - 156, http://dx.doi.org/10.1111/j.1365-2885.2006.00727.x
,2005, 'Oxaliplatin causes selective atrophy of a subpopulation of dorsal root ganglion neurons without inducing cell loss', Cancer Chemotherapy and Pharmacology, 56, pp. 391 - 399, http://dx.doi.org/10.1007/s00280-004-0953-4
,2003, 'Paclitaxel induces nucleolar enlargement in dorsal root ganglion neurons in vivo reducing oxaliplatin toxicity', British Journal of Cancer, 88, pp. 1942 - 1947, http://dx.doi.org/10.1038/sj.bjc.6601012
,2003, 'Pharmacokinetics of florfenicol in healthy pigs and in pigs experimentally infected with Actinobacillus pleuropneumoniae', Antimicrobial Agents and Chemotherapy, 47, pp. 820 - 823, http://dx.doi.org/10.1128/AAC.47.2.820-823.2003
,2002, 'Tissue pharmacokinetics of florfenicol in pigs experimentally infected with Actinobacillus pleuropneumoniae', European Journal of Drug Metabolism and Pharmacokinetics, 27, pp. 265 - 271, http://dx.doi.org/10.1007/BF03192337
,Conference Papers
2004, 'Application of liquid chromatography-mass spectrometry to monitoring plasma cyclophosphamide levels in phase I trial cancer patients', in Clinical and Experimental Pharmacology and Physiology, pp. 677 - 682, http://dx.doi.org/10.1111/j.1440-1681.2004.03065.x
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