By Dr Julian Singer

Journal articles

Perkins GB; Tunbridge MJ; Chai CS; Hope CM; Yeow AEL; Salehi T; Singer J; Shi B; Masavuli MG; Mekonnen ZA; Garcia-Valtanen P; Kireta S; Johnston JK; Drogemuller CJ; Sim BZ; Spencer SM; Sallustio BC; Comerford I; Bouras G; Weiskopf D; Sette A; Aggarwal A; Milogiannakis V; Akerman A; Turville S; Hurtado PR; Ying T; Hissaria P; Barry SC; Chadban SJ; Grubor-Bauk B; Coates PT, 2025, 'Mechanistic Target of Rapamycin Inhibitors and Vaccine Response in Kidney Transplant Recipients', Journal of the American Society of Nephrology, 36, pp. 2213 - 2227, http://dx.doi.org/10.1681/ASN.0000000716

Schegerer AA; Stamm G; Aberle C; Ammon J; Bazrafshan B; Borowski M; Eßeling R; Madsack B; Menz R; Müller C; Oberhofer N; Renger B; Singer J; Verius M; Walz M; Jungnickel K, 2025, 'International survey on diagnostic reference levels based on clinical indications in plain radiography', European Radiology, 35, pp. 3336 - 3346, http://dx.doi.org/10.1007/s00330-024-11224-2

Singer J; Tunbridge MJ; Shi B; Perkins GB; Chai CS; Salehi T; Sim BZ; Kireta S; Johnston JK; Akerman A; Milogiannakis V; Aggarwal A; Turville S; Hissaria P; Ying T; Wu H; Grubor-Bauk B; Coates PT; Chadban SJ, 2024, 'Dietary Inulin to Improve SARS-CoV-2 Vaccine Response in Kidney Transplant Recipients: The RIVASTIM-Inulin Randomised Controlled Trial', Vaccines, 12, http://dx.doi.org/10.3390/vaccines12060608

Chadban SJ; Singer J; Coates PT, 2023, 'That sinking gut feeling: is transplant-induced dysbiosis contributing to allograft outcomes?', Kidney International, 103, pp. 454 - 457, http://dx.doi.org/10.1016/j.kint.2022.11.022

Manava P; Galster M; Ammon J; Singer J; Lell MM; Rieger V, 2023, 'Optimized Camera-Based Patient Positioning in CT', Investigative Radiology, 58, pp. 126 - 130, http://dx.doi.org/10.1097/rli.0000000000000904

Tunbridge M; Perkins GB; Singer J; Salehi T; Ying T; Grubor-Bauk B; Barry S; Sim B; Hissaria P; Chadban SJ; Coates PT, 2022, 'Rapamycin and inulin for booster vaccine response stimulation (RIVASTIM)—rapamycin: study protocol for a randomised, controlled trial of immunosuppression modification with rapamycin to improve SARS-CoV-2 vaccine response in kidney transplant recipients', Trials, 23, http://dx.doi.org/10.1186/s13063-022-06634-w

Singer J; Tunbridge M; Perkins GB; Salehi T; Ying T; Wu H; Coates PT; Chadban SJ, 2022, 'Rapamycin and inulin for third-dose vaccine response stimulation (RIVASTIM): Inulin - Study protocol for a pilot, multicentre, randomised, double-blinded, controlled trial of dietary inulin to improve SARS-CoV-2 vaccine response in kidney transplant recipients', BMJ Open, 12, http://dx.doi.org/10.1136/bmjopen-2022-062747

Lai C; Chadban SJ; Loh YW; Kwan TKT; Wang C; Singer J; Niewold P; Ling Z; Spiteri A; Getts D; King NJC; Wu H, 2022, 'Targeting inflammatory monocytes by immune-modifying nanoparticles prevents acute kidney allograft rejection', Kidney International, 102, pp. 1090 - 1102, http://dx.doi.org/10.1016/j.kint.2022.06.024

Perkins GB; Tunbridge M; Salehi T; Chai CS; Kireta S; Johnston J; Penko D; Nitschke J; Yeow AEL; Al-Delfi Z; Drogemuller CJ; Garcia-Valtanen P; Masavuli MG; Hope CM; Singer J; Aggarwal A; Ospina Stella A; Turville SG; Hurtado PR; Barry SC; Hissaria P; Grubor-Bauk B; Chadban SJ; Coates PT, 2022, 'Concurrent vaccination of kidney transplant recipients and close household cohabitants against COVID-19', Kidney International, 101, pp. 1077 - 1080, http://dx.doi.org/10.1016/j.kint.2022.02.015

Singer J; Aouad LJ; Wyburn K; Gracey DM; Ying T; Chadban SJ, 2022, 'The Utility of Pre- and Post-Transplant Oral Glucose Tolerance Tests: Identifying Kidney Transplant Recipients With or at Risk of New Onset Diabetes After Transplant', Transplant International, 35, http://dx.doi.org/10.3389/ti.2022.10078

Perkins G; Tunbridge M; Salehi T; Sheng Chai C; Hope CM; Garcia-Valtanen P; Singer JJ; Hurtado PR; Turville S; Hissaria P; Grubor-Bauk B; Barry SC; Chadban SJ; Coates AO T, 2022, '314.2: MTOR Inhibitors Promote Highly Functional T Cell Immunity in Kidney Transplant Recipients Vaccinated Against COVID-19', Transplantation, 106, pp. S223 - S223, http://dx.doi.org/10.1097/01.tp.0000886512.07666.7d

Mueller BS; Singer J; Stamm G; Pirl L; Borowski M; Hertlein T; Rerich E; Trinkl S; Wucherer M; Ammon J, 2022, 'Handling of Incidents in the Clinical Application of Ionizing Radiation in Diagnostic and Interventional Radiology - a Multi-center Study', ROFO-FORTSCHRITTE AUF DEM GEBIET DER RONTGENSTRAHLEN UND DER BILDGEBENDEN VERFAHREN, 194, pp. 400 - 408, http://dx.doi.org/10.1055/a-1665-6988

Burgess A; Matar E; Roberts C; Haq I; Wynter L; Singer J; Kalman E; Bleasel J, 2021, 'Scaffolding medical student knowledge and skills: team-based learning (TBL) and case-based learning (CBL)', BMC Medical Education, 21, http://dx.doi.org/10.1186/s12909-021-02638-3

Liu Y; Li YJ; Loh YW; Singer J; Zhu W; Macia L; Mackay CR; Wang W; Chadban SJ; Wu H, 2021, 'Fiber Derived Microbial Metabolites Prevent Acute Kidney Injury Through G-Protein Coupled Receptors and HDAC Inhibition', Frontiers in Cell and Developmental Biology, 9, http://dx.doi.org/10.3389/fcell.2021.648639

Singer J; Li YJ; Ying T; Aouad LJ; Gracey DM; Wyburn K; Macia L; Wu H; Chadban SJ, 2021, 'Protocol for a pilot single-centre, parallel-arm, randomised controlled trial of dietary inulin to improve gut health in solid organ transplantation: The DIGEST study', BMJ Open, 11, http://dx.doi.org/10.1136/bmjopen-2021-049184

Wu H; Singer J; Kwan TK; Loh YW; Wang C; Tan J; Li YJ; Lai SWC; Macia L; Alexander SI; Chadban SJ, 2020, 'Gut microbial metabolites induce donor-specific tolerance of kidney allografts through induction of T regulatory cells by short-chain fatty acids', Journal of the American Society of Nephrology, 31, pp. 1445 - 1461, http://dx.doi.org/10.1681/ASN.2019080852

Li YJ; Chen X; Kwan TK; Loh YW; Singer J; Liu Y; Ma J; Tan J; Macia L; Mackay CR; Chadban SJ; Wu H, 2020, 'Dietary fiber protects against diabetic nephropathy through short-chain fatty acid-mediated activation of G protein-coupled receptors GPR43 and GPR109A', Journal of the American Society of Nephrology, 31, pp. 1267 - 1281, http://dx.doi.org/10.1681/ASN.2019101029

Singer J; Wu H; Loh YW; Li YJ; Wang C; Tan J; Macia L; Kwan TK; Alexander SI; Chadban SJ, 2020, 'HIGH-FIBRE DIET REDUCES TRANSPLANT-ASSOCIATED DYSBIOSIS AND IMPROVES RENAL ALLOGRAFT SURVIVAL IN A MURINE MODEL OF KIDNEY ALLOGRAFT REJECTION', Transplantation, 104, pp. S188 - S189, http://dx.doi.org/10.1097/01.tp.0000699324.20398.8c

Li Y; Chen X; Kwan T; Loh Y; Singer J; Liu Y; Tan J; Macia L; Chadban S; Wu H, 2020, 'SAT-160 DIETARY FIBRE AND BACTERIAL SCFA MODULATE RENAL INFLAMMATION IN DIABETIC NEPHROPATHY THROUGH ACTIVATION OF G-PROTEIN COUPLED RECEPTORS GPR43 AND GPR109A', Kidney International Reports, 5, pp. S68 - S69, http://dx.doi.org/10.1016/j.ekir.2020.02.170

Liu Y; LI Y; Loh YW; Singer J; Macia L; Chadban S; Wu H, 2020, 'SUN-040 MANIPULATING THE GUT MICROBIOME BY DIETARY FIBRE TO PREVENT FOLIC ACID INDUCED KIDNEY DISEASE', Kidney International Reports, 5, pp. S221 - S221, http://dx.doi.org/10.1016/j.ekir.2020.02.563

Lai C; Chadban S; Singer J; Loh YW; Niewold P; Getts D; King N; Wu H, 2020, 'TARGETING INFLAMMATORY MONOCYTES BY IMMUNE-MODIFYING NANOPARTICLES PREVENTS ACUTE KIDNEY ALLOGRAFT REJECTION', Transplantation, 104, pp. S45 - S45, http://dx.doi.org/10.1097/01.tp.0000698480.25386.59

LI Y; Chen X; Kwan T; Loh Y; Singer J; Tan J; Macia L; Chadban S; Wu H, 2019, 'SUN-303 DIETARY MANIPULATION OF THE GUT MICROBIOTA REDUCES DIABETIC KIDNEY INJURY IN MICE', Kidney International Reports, 4, pp. S285 - S286, http://dx.doi.org/10.1016/j.ekir.2019.05.709

Tangirala N; Singer J; Snelling P; Wyburn K; Chadban S; Aouad L; Gracey DM, 2018, 'Emphysematous pyelonpehritis in a dual kidney transplant recipient', Nephrology, 23, pp. 1064 - 1065, http://dx.doi.org/10.1111/nep.13258

Vaidya JS; Bulsara M; Wenz F; Coombs N; Singer J; Ebbs S; Massarut S; Saunders C; Douek M; Williams N; Joseph D; Tobias JS; Baum M, 2016, 'Reduced Mortality With Partial Breast Irradiation for Early Breast Cancer Reply', INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 96, pp. 707 - +, http://dx.doi.org/10.1016/j.ijrobp.2016.06.2461

Coombs NJ; Coombs JM; Vaidya UJ; Singer J; Bulsara M; Tobias JS; Wenz F; Joseph DJ; Brown DA; Rainsbury R; Davidson T; Adamson DJA; Massarut S; Morgan D; Potyka I; Corica T; Falzon M; Williams N; Baum M; Vaidya JS, 2016, 'Environmental and social benefits of the targeted intraoperative radiotherapy for breast cancer: data from UK TARGIT-A trial centres and two UK NHS hospitals offering TARGIT IORT', BMJ Open, 6, pp. e010703, http://dx.doi.org/10.1136/bmjopen-2015-010703

Vaidya JS; Bulsara M; Wenz F; Coombs N; Singer J; Ebbs S; Massarut S; Saunders C; Douek M; Williams NR; Joseph D; Tobias JS; Baum M, 2016, 'Reduced Mortality With Partial-Breast Irradiation for Early Breast Cancer: A Meta-Analysis of Randomized Trials', International Journal of Radiation Oncology • Biology • Physics, 96, pp. 259 - 265, http://dx.doi.org/10.1016/j.ijrobp.2016.05.008

Grossmann M; Kiessling F; Singer J; Schoeman H; Schroeder M-B; von Wallbrunn C, 2011, 'Genetically modified wine yeasts and risk assessment studies covering different steps within the wine making process', ANNALS OF MICROBIOLOGY, 61, pp. 103 - 115, http://dx.doi.org/10.1007/s13213-010-0088-2

Zou H; Lifshitz LM; Tuft RA; Fogarty KE; Singer JJ, 2005, 'Using total fluorescence increase (signal mass) to determine the Ca²⁺ current underlying localized Ca²⁺ events (vol 124, pg 259, 2004)', JOURNAL OF GENERAL PHYSIOLOGY, 126, pp. 539 - 539, http://dx.doi.org/10.1085/jgp.200409066101705c

Zou H; Lifshitz LM; Tuft RA; Fogarty KE; Singer JJ, 2004, 'Using Total Fluorescence Increase (Signal Mass) to Determine the Ca2+ Current Underlying Localized Ca2+ Events', Journal of General Physiology, 124, pp. 259 - 272, http://dx.doi.org/10.1085/jgp.200409066

Zou H; Lifshitz LM; Tuft RA; Fogarty KE; Singer JJ, 2004, 'Imaging calcium entering the cytosol through a single opening of plasma membrane ion channels: SCCaFTs - fundamental calcium events', CELL CALCIUM, 35, pp. 523 - 533, http://dx.doi.org/10.1016/j.ceca.2004.01.019

Clarke AL; Petrou S; Walsh JV; Singer JJ, 2003, 'Site of action of fatty acids and other charged lipids on BKCa channels from arterial smooth muscle cells', American Journal of Physiology - Cell Physiology, 284, pp. c607 - c619, http://dx.doi.org/10.1152/ajpcell.00364.2002

Zou H; Lifshitz LM; Tuft RA; Fogarty KE; Singer JJ, 2002, 'Visualization of Ca2+ entry through single stretch-activated cation channels', Proceedings of the National Academy of Sciences of the United States of America, 99, pp. 6404 - 6409, http://dx.doi.org/10.1073/pnas.092654999

Clarke AL; Petrou S; Walsh JV; Singer JJ, 2002, 'Modulation of BK_Ca channel activity by fatty acids: structural requirements and mechanism of action', AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 283, pp. C1441 - C1453, http://dx.doi.org/10.1152/ajpcell.00035.2002

Dopico AM; Walsh JV; Singer JJ, 2002, 'Natural bile acids and synthetic analogues modulate large conductance Ca²⁺-activated K⁺ (BK_Ca) channel activity in smooth muscle cells', JOURNAL OF GENERAL PHYSIOLOGY, 119, pp. 251 - 273, http://dx.doi.org/10.1085/jgp.119.3.251

Zou H; Ugur M; Drummond RM; Singer JJ, 2001, 'Coupling of a P2Z-like purinoceptor to a fatty acid-activated K⁺ channel in toad gastric smooth muscle cells', JOURNAL OF PHYSIOLOGY-LONDON, 534, pp. 59 - 70, http://dx.doi.org/10.1111/j.1469-7793.2001.00059.x

Kirber MT; Guerrero‐Hernández A; Bowman DS; Fogarty KE; Tuft RA; Singer JJ; Fay FS, 2000, 'Multiple pathways responsible for the stretch‐induced increase in Ca2+ concentration in toad stomach smooth muscle cells', The Journal of Physiology, 524, pp. 3 - 17, http://dx.doi.org/10.1111/j.1469-7793.2000.t01-4-00003.x

Vazan A; Awad J; Elami A; Rudis E; Gilon D; Singer JJ; Aydinalp A; Roguin N, 1999, 'Hydatid cysts of the heart', CIRCULATION, 100, pp. E42 - E44

Zou H; Lifshitz LM; Tuft RA; Fogarty KE; Singer JJ, 1999, 'Imaging Ca²⁺ entering the cytoplasm through a single opening of a plasma membrane cation channel', JOURNAL OF GENERAL PHYSIOLOGY, 114, pp. 575 - 588, http://dx.doi.org/10.1085/jgp.114.4.575

Zou H; Lifshitz LM; Tuft RA; Fogarty KE; Singer JJ, 1999, 'Imaging Ca2+ entering the cytoplasm through a single opening of a plasma membrane cation channel (vol 114, pg 575, 1999)', JOURNAL OF GENERAL PHYSIOLOGY, 114, pp. 839 - 839

Petrou S; Ugur M; Drummond RM; Singer JJ; Walsh JV, 1997, 'P2X7 purinoceptor expression in Xenopus oocytes is not sufficient to produce a pore‐forming P2Z‐like phenotype', FEBS Letters, 411, pp. 339 - 345, http://dx.doi.org/10.1016/s0014-5793(97)00700-x

Ugur M; Drummond RM; Zou H; Sheng P; Singer JJ; Walsh JV, 1997, 'An ATP‐gated cation channel with some P2Z‐like characteristics in gastric smooth muscle cells of toad.', The Journal of Physiology, 498, pp. 427 - 442, http://dx.doi.org/10.1113/jphysiol.1997.sp021869

ORDWAY RW; PETROU S; KIRBER MT; WALSH JV; SINGER JJ, 1995, 'STRETCH ACTIVATION OF A TOAD SMOOTH-MUSCLE K+ CHANNEL MAY BE MEDIATED BY FATTY-ACIDS', JOURNAL OF PHYSIOLOGY-LONDON, 484, pp. 331 - 337, http://dx.doi.org/10.1113/jphysiol.1995.sp020668

Guerrero A; Fay FS; Singer JJ, 1994, 'Caffeine activates a Ca(2+)-permeable, nonselective cation channel in smooth muscle cells.', Journal of General Physiology, 104, pp. 375 - 394, http://dx.doi.org/10.1085/jgp.104.2.375

Dopico AM; Kirber MT; Singer JJ; Walsh JV, 1994, 'Membrane Stretch Directly Activates Large Conductance Ca2+-Activated K+ Channels in Mesenteric Artery Smooth Muscle Cells', American Journal of Hypertension, 7, pp. 82 - 89, http://dx.doi.org/10.1093/ajh/7.1.82

GUERRERO A; SINGER JJ; FAY FS, 1994, 'SIMULTANEOUS MEASUREMENT OF CA2+ RELEASE AND INFLUX INTO SMOOTH-MUSCLE CELLS IN RESPONSE TO CAFFEINE - A NOVEL-APPROACH FOR CALCULATING THE FRACTION OF CURRENT CARRIED BY CALCIUM', JOURNAL OF GENERAL PHYSIOLOGY, 104, pp. 395 - 422, http://dx.doi.org/10.1085/jgp.104.2.395

PETROU S; ORDWAY RW; HAMILTON JA; WALSH JV; SINGER JJ, 1994, 'STRUCTURAL REQUIREMENTS FOR CHARGED LIPID MOLECULES TO DIRECTLY INCREASE OR SUPPRESS K+ CHANNEL ACTIVITY IN SMOOTH-MUSCLE CELLS - EFFECTS OF FATTY-ACIDS, LYSOPHOSPHATIDATE, ACYL COENZYME-A AND SPHINGOSINE', JOURNAL OF GENERAL PHYSIOLOGY, 103, pp. 471 - 486, http://dx.doi.org/10.1085/jgp.103.3.471

PETROU S; ORDWAY RW; SINGER JJ; WALSH JV, 1993, 'A PUTATIVE FATTY ACID-BINDING DOMAIN OF THE NMDA RECEPTOR', TRENDS IN BIOCHEMICAL SCIENCES, 18, pp. 41 - 42, http://dx.doi.org/10.1016/0968-0004(93)90050-W

HISADA T; SINGER JJ; WALSH JV, 1993, 'ALUMINOFLUORIDE ACTIVATES HYPERPOLARIZATION-ACTIVATED AND STRETCH-ACTIVATED CATIONIC CHANNELS IN SINGLE SMOOTH-MUSCLE CELLS', PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 422, pp. 397 - 400, http://dx.doi.org/10.1007/BF00374297

Hisada T; Walsh JV; Singer JJ, 1993, 'Stretch-inactivated cationic channels in single smooth muscle cells', Pflügers Archiv - European Journal of Physiology, 422, pp. 393 - 396, http://dx.doi.org/10.1007/bf00374296

Kirber MT; Ordway RW; Clapp LH; Walsh JV; Singer JJ, 1992, 'Both membrane stretch and fatty acids directly activate large conductance Ca2+‐activated K+ channels in vascular smooth muscle cells', FEBS Letters, 297, pp. 24 - 28, http://dx.doi.org/10.1016/0014-5793(92)80319-c

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