By Dr Leon Stephen Edwards

Journal articles

Edwards LS; Cappelen-Smith C; Cordato D; Bivard A; Churilov L; Lin L; Chen C; Garcia-Esperon C; Parsons MW, 2025, 'Optimizing CTP in Posterior Circulation Infarction (POCI): A Comprehensive Analysis of CTP Postprocessing Algorithms for POCI', American Journal of Neuroradiology, 46, pp. 2243 - 2252, http://dx.doi.org/10.3174/ajnr.A8833

Wong JJC; Tran J; Bakshi M; Hwang YT; Lee R; Edwards L, 2025, 'Loeys-Dietz syndrome 3 causing vertebral artery dissections with posterior circulation strokes', Practical Neurology, http://dx.doi.org/10.1136/pn-2025-004566

Ouyang M; You S; Moullaali TJ; Delcourt C; Sandset EC; Woodhouse L; Law ZK; Arima H; Butcher K; Edwards LS; Gupta S; Jiang W; Koch S; Potter J; Qureshi AI; Robinson TG; Al-Shahi Salman R; Saver JL; Sprigg N; Wardlaw J; Anderson CS; Bath PM; Chalmers JP; Wang X, 2025, 'Trajectory of Hematoma Growth and Functional Recovery after Intracerebral Hemorrhage: A Latent Class Analysis of Blood Pressure in Acute Stroke Collaboration Data', Cerebrovascular Diseases, http://dx.doi.org/10.1159/000547678

Parsons MW; Yogendrakumar V; Churilov L; Garcia-Esperon C; Campbell BCV; Russell ML; Sharma G; Chen C; Lin L; Chew BL; Ng FC; Deepak A; Choi PMC; Kleinig TJ; Cordato DJ; Wu TY; Fink JN; Ma H; Phan TG; Markus HS; Molina CA; Tsai CH; Lee JT; Jeng JS; Strbian D; Meretoja A; Arenillas JF; Buck BH; Devlin MJ; Brown H; Butcher KS; O'Brien B; Sabet A; Wijeratne T; Bivard A; Grimley RS; Agarwal S; Munshi SK; Donnan GA; Davis SM; Miteff F; Spratt NJ; Levi CR; Phan T; Selmes C; Lees K; Kaste M; MacIsaac R; Wellings T; Loiselle A; Pepper E; Krishnamurthy V; Ang T; Alanati K; Gangadharan S; Zareie H; Starling R; Dunkerton S; He J; Datta R; Royan A; Kerr E; Kaauwai L; Belevski L; Ormond S; Johnson A; Evans M; Lachapelle N; Ombelet F; Bladin C; Dewey H; Wong J; Park P; Cody R; Tan P; Callaly E; Senanayake C; Thomas G; Liu J; Busch T; Stuart N; Chung M; Yassi N; Valente M; Sharobeam A; Cooley R; Zhao H; Alemseged F; Williams C; Ng JL; Balabanski A; dos Santos A; Williamson J; Pavlin-Premrl D; Beharry J; Ma M; Park A; Yan B; Hand P; Jackson D, 2024, 'Tenecteplase versus alteplase for thrombolysis in patients selected by use of perfusion imaging within 4·5 h of onset of ischaemic stroke (TASTE): a multicentre, randomised, controlled, phase 3 non-inferiority trial', Lancet Neurology, 23, pp. 775 - 786, http://dx.doi.org/10.1016/S1474-4422(24)00206-0

Alysha D; Blair C; Thomas P; Pham T; Nguyen T; Cordato TR; Badge H; Chappelow N; Lin L; Edwards L; Thomas J; Hodgkinson S; Cappelen-Smith C; McDougall A; Cordato DJ; Parsons M, 2024, 'Comparative Prevalence of Cerebrovascular Disease in Vietnamese Communities in South-Western Sydney', Journal of Cardiovascular Development and Disease, 11, http://dx.doi.org/10.3390/jcdd11060164

Wang X; Yang J; Moullaali TJ; Sandset EC; Woodhouse LJ; Law ZK; Arima H; Butcher KS; Delcourt C; Edwards L; Gupta S; Jiang W; Koch S; Potter J; Qureshi AI; Robinson TG; Al-Shahi Salman R; Saver JL; Sprigg N; Wardlaw J; Anderson CS; Sakamoto Y; Bath PM; Chalmers J, 2024, 'Influence of Time to Achieve Target Systolic Blood Pressure on Outcome after Intracerebral Hemorrhage: The Blood Pressure in Acute Stroke Collaboration', Stroke, 55, pp. 849 - 855, http://dx.doi.org/10.1161/STROKEAHA.123.044358

Garcia-Esperon C; Maltby S; Butcher K; Hasnain MG; Chew BLA; O'Brien W; Evans JW; Ang T; Edwards L; Blair C; Delcourt C; Parsons MW; Miteff F; Dizon J; Lambkin D; Barker D; Kluge MG; Wiggers JH; Levi CR; Spratt NJ; Walker FR, 2024, 'Rollout of a statewide Australian telestroke network including virtual reality training is associated with improved hyperacute stroke workflow metrics and thrombolysis rate', Frontiers in Stroke, 3, http://dx.doi.org/10.3389/fstro.2024.1382608

Zhao YC; Zhang Y; Nasser A; Hong T; Wang Z; Sun A; Moldovan L; Edwards LS; Passam F; Butcher KS; Ang T; Ju LA, 2023, 'Movable typing of full-lumen personalized Vein-Chips to model cerebral venous sinus thrombosis', Aggregate, 4, http://dx.doi.org/10.1002/agt2.386

Nagaratnam SA; Edwards L; Blair C; Evans J; O'Brien W, 2023, 'Functional outcomes of patients with ischaemic stroke with known atrial fibrillation not on therapeutic anticoagulation', Internal Medicine Journal, 53, pp. 1987 - 1993, http://dx.doi.org/10.1111/imj.16044

Edwards LS; Cappelen-Smith C; Cordato D; Bivard A; Churilov L; Lin L; Chen C; Garcia-Esperon C; Butcher K; Kleinig T; Choi PMC; Cheng X; Dong Q; Aviv RI; Parsons MW, 2023, 'Optimal CT perfusion thresholds for core and penumbra in acute posterior circulation infarction', Frontiers in Neurology, 14, http://dx.doi.org/10.3389/fneur.2023.1092505

Roaldsen MB; Eltoft A; Wilsgaard T; Christensen H; Engelter ST; Indredavik B; Jatužis D; Karelis G; Kõrv J; Lundström E; Petersson J; Putaala J; Søyland MH; Tveiten A; Bivard A; Johnsen SH; Mazya MV; Werring DJ; Wu TY; De Marchis GM; Robinson TG; Mathiesen EB; Parson M; Valente M; Chen A; Sharobeam A; Edwards L; Blair C; Christensen L; Ægidius K; Pihl T; Fassel-Larsen C; Wassvik L; Folke M; Rosenbaum S; Gharehbagh SS; Hansen A; Preisler N; Antsov K; Mallene S; Lill M; Herodes M; Vibo R; Rakitin A; Saarinen J; Tiainen M; Tumpula O; Noppari T; Raty S; Sibolt G; Nieminen J; Niederhauser J; Haritoncenko I; Puustinen J; Haula TM; Sipilä J; Viesulaite B; Taroza S; Rastenyte D; Matijosaitis V; Vilionskis A; Masiliunas R; Ekkert A; Chmeliauskas P; Lukosaitis V; Reichenbach A; Moss TT; Nilsen HY; Hammer-Berntzen R; Nordby LM; Weiby TA; Nordengen K; Ihle-Hansen H; Stankiewiecz M; Grotle O; Nes M; Thiemann K; Særvold IM; Fraas M; Størdahl S; Horn JW; Hildrum H; Myrstad C; Tobro H; Tunvold JA; Jacobsen O; Aamodt N; Baisa H; Malmberg VN; Rohweder G; Ellekjær H; Ildstad F; Egstad E; Helleberg BH; Berg HH; Jørgensen J; Tronvik E; Shirzadi M; Solhoff R; Van Lessen R, 2023, 'Safety and efficacy of tenecteplase in patients with wake-up stroke assessed by non-contrast CT (TWIST): a multicentre, open-label, randomised controlled trial', Lancet Neurology, 22, pp. 117 - 126, http://dx.doi.org/10.1016/S1474-4422(22)00484-7

Cordato D; Blair C; Thomas P; Firtko A; Miller M; Edwards LS; Thomas J; Balabanski AH; Dos Santos A; Lin L; Hodgkinson S; Cappelen-Smith C; Beran RG; McDougall A; Parsons M, 2022, 'Cerebrovascular Disease Profiles of Culturally and Linguistically Diverse Communities in South Western Sydney and New South Wales', Cerebrovascular Diseases, 51, pp. 744 - 754, http://dx.doi.org/10.1159/000524242

Arora K; Gaekwad A; Evans J; O'Brien W; Ang T; Garcia-Esperon C; Blair C; Edwards LS; Chew BLA; Delcourt C; Spratt NJ; Parsons MW; Butcher KS, 2022, 'Diagnostic Utility of Computed Tomography Perfusion in the Telestroke Setting', Stroke, 53, pp. 2917 - 2925, http://dx.doi.org/10.1161/STROKEAHA.122.038798

Mitchell PJ; Yan B; Churilov L; Dowling RJ; Bush SJ; Bivard A; Huo XC; Wang G; Zhang SY; Ton MD; Cordato DJ; Kleinig TJ; Ma H; Chandra RV; Brown H; Campbell BCV; Cheung AK; Steinfort B; Scroop R; Redmond K; Miteff F; Liu Y; Duc DP; Rice H; Parsons MW; Wu TY; Nguyen HT; Donnan GA; Miao ZR; Davis SM; Desmond P; Yassi N; Zhao H; Williams C; Alemseged F; Ng FC; Yogendrakumar V; Bailey P; De Villiers L; Phan T; Thirugnanachandran T; Chong W; Asadi H; Slater LA; Manning N; Wenderoth J; McDougall A; Cappelen-Smith C; Whitley J; Edwards L; Esperon CG; Spratt N; Pepper E; Levi C; Faulder K; Harrington T; Krause M; Waters M; Fink J; Ma G; Shen X; Song X; Gao Y; Guangxian N; Guo Z; Zhang H; Han H; Wang H; Liao G; Zhang Z; Li C; Yang Z; Cai C; Huang C; Hong Y, 2022, 'Endovascular thrombectomy versus standard bridging thrombolytic with endovascular thrombectomy within 4·5 h of stroke onset: an open-label, blinded-endpoint, randomised non-inferiority trial', Lancet, 400, pp. 116 - 125, http://dx.doi.org/10.1016/S0140-6736(22)00564-5

Blair C; Firtko A; Thomas P; Lin L; Miller M; Tran L; Edwards L; Bhaskar S; Parsons M; Cordato DJ, 2022, 'A Multicentre Study Comparing Cerebrovascular Disease Profiles in Pacific Islander and Caucasian Populations Presenting with Stroke and Transient Ischaemic Attack', Neuroepidemiology, 56, pp. 25 - 31, http://dx.doi.org/10.1159/000520058

Goire N; Edwards L; Thomas P; Bhaskar SMM; Cordato D; Buckland ME; Beran RG, 2022, 'Creutzfeldt-Jakob Disease in South West Sydney 2014–2020: An Unusually High Incidence of a Rare Disease', Neuroepidemiology, 56, pp. 59 - 65, http://dx.doi.org/10.1159/000520736

Moullaali TJ; Wang X; Sandset EC; Woodhouse LJ; Law ZK; Arima H; Butcher KS; Chalmers J; Delcourt C; Edwards L; Gupta S; Jiang W; Koch S; Potter J; Qureshi AI; Robinson TG; Al-Shahi Salman R; Saver JL; Sprigg N; Wardlaw JM; Anderson CS; Bath PM, 2022, 'Early lowering of blood pressure after acute intracerebral haemorrhage: a systematic review and meta-analysis of individual patient data', Journal of neurology, neurosurgery, and psychiatry, 93, pp. 6 - 13, http://dx.doi.org/10.1136/jnnp-2021-327195

Arora K; Gaekwad A; Evans J; O'Brien W; Ang T; Garcia-Esperon C; Blair C; Edwards LS; Chew BLA; Delcourt C; Spratt NJ; Parsons MW; Butcher KS, 2022, 'Diagnostic Utility of Computed Tomography Perfusion in the Telestroke Setting (vol 53, pg 2917, 2022)', STROKE, 53, pp. E439 - E439, http://dx.doi.org/10.1161/STR.0000000000000412

Fibbins H; Edwards L; Morell R; Lederman O; Ward P; Curtis J, 2021, 'Implementing an Exercise Physiology Clinic for Consumers Within a Community Mental Health Service: A Real-World Evaluation', Frontiers in Psychiatry, 12, http://dx.doi.org/10.3389/fpsyt.2021.791125

Blair C; Edwards L; Cappelen-Smith C; Cordato D; Cheung A; Wenderoth J; McQuinn A; Manning NW, 2021, 'Intravenous Thrombolysis Is Associated with Less Disabling Stroke and Lower Mortality in Multiple-Pass Endovascular Thrombectomy', Cerebrovascular Diseases, 50, pp. 156 - 161, http://dx.doi.org/10.1159/000512105

Fu J; Cappelen-Smith C; Edwards L; Cheung A; Manning N; Wenderoth J; Parsons M; Cordato D, 2021, 'Comparison of functional outcomes after endovascular thrombectomy in patients with and without atrial fibrillation', Vessel Plus, 5, http://dx.doi.org/10.20517/2574-1209.2021.36

Edwards LS; Cappelen-Smith C; Cordato D; Bivard A; Churilov L; Parsons MW, 2021, 'Review of CT perfusion and current applications in posterior circulation stroke', Vessel Plus, 5, http://dx.doi.org/10.20517/2574-1209.2021.18

Kim LN; Edwards L; Goonetilleke N; Kane A; McDougall A; Calic Z, 2020, 'Bortezomib for the treatment of refractory anti-N-methyl-d-aspartate receptor encephalitis', Internal Medicine Journal, 50, pp. 1591 - 1592, http://dx.doi.org/10.1111/imj.15118

Edwards LS; Beran RG, 2020, 'Lamotrigine — Interactions matter!', Epilepsy and Behavior, 111, http://dx.doi.org/10.1016/j.yebeh.2020.107333

Edwards LS; Cuganesan R; Cappelen-Smith C, 2020, 'Cerebral venous thrombosis as a complication of intracranial hypotension after lumbar puncture', BMJ Neurology Open, 2, pp. 1 - 2, http://dx.doi.org/10.1136/bmjno-2020-000046

Edwards LS; Halmagyi GM; Mallawaarachchi A; Thompson EO; Kiernan MC, 2020, 'Fatal cerebellar oedema in adult Leigh syndrome', Practical Neurology, 20, pp. 338 - 339, http://dx.doi.org/10.1136/practneurol-2019-002409

Blair C; Cappelen-Smith C; Cordato D; Edwards L; Mitchelle A; Cheung A; Wenderoth J; Manning N, 2020, 'Abstract TP28: Intravenous Thrombolysis is Associated With Better Functional Outcomes in Endovascular Thrombectomy Patients Requiring Multiple-Passes to Achieve Reperfusion', Stroke, 51, http://dx.doi.org/10.1161/str.51.suppl_1.tp28

Edwards LS; Blair C; Cordato D; McDougall A; Manning N; Cheung A; Wenderoth J; Cappelen-Smith C, 2020, 'Impact of interhospital transfer on patients undergoing endovascular thrombectomy for acute ischaemic stroke in an Australian setting', BMJ Neurology Open, 2, pp. e000030 - e000030, http://dx.doi.org/10.1136/bmjno-2019-000030

Blair C; Tremonti C; Edwards L; Haber PS; Halmagyi GM, 2019, 'Vitamin B12 supplementation futile for preventing demyelination in ongoing nitrous oxide misuse', Medical Journal of Australia, 211, pp. 428 - 428.e1, http://dx.doi.org/10.5694/mja2.50371

Blair C; Tremonti C; Edwards L; Haber P; Halmagyi M, 2019, 'CASE SERIES: SUBACUTE COMBINED DEGENERATION OF THE SPINAL CORD IN VITAMIN B12-REPLETE RECREATIONAL NITROUS OXIDE ABUSERS', JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 90, http://dx.doi.org/10.1136/jnnp-2019-anzan.105

Edwards LS; Halmagyi GM; Barnett MH; Blair CA; Kiernan MC, 2019, 'Cerebellar oedema in fulminant adult leigh syndrome', JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 90, http://dx.doi.org/10.1136/jnnp-2019-anzan.79

Edwards LS; Tchan M; Crossley KM; Yee B; Spies JM, 2019, 'LATE-ONSET POMPE DISEASE (LOPD) PRESENTING WITH FULMINANT HYPERCAPNIC RESPIRATORY FAILURE', JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 90, http://dx.doi.org/10.1136/jnnp-2019-anzan.113

Edwards LS; Barnett MH; Kieman MC, 2018, 'RITUXIMAB AND MAINTENANCE MYCOPHENOLATE MOFETIL FOR TREATMENT OF REFRACTORY ANTI-N-METHYL-D-ASPARTATE-RECEPTOR (NMDAR) ENCEPHALITIS', JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 89, pp. E44 - E45, http://dx.doi.org/10.1136/jnnp-2018-ANZAN.112

Edwards L; Ranasinghe I; Brieger D, 2012, 'Evaluating the Performance of the Can Rapid Risk Stratification of Unstable Angina Patients Suppress Adverse Outcomes with Early Implementation of the ACC/AHA Guidelines (CRUSADE) and the Reduction of Atherothrombosis for Continued Health (REACH) Bleeding Scores in the Australian and New Zealand (ANZ) Acute Coronary Syndrome (ACS) Population', Heart, Lung and Circulation, 21, pp. S250 - S250, http://dx.doi.org/10.1016/j.hlc.2012.05.614

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