By Dr Michael John Carnell

Journal articles

Wang D; Wang Y; Di X; Wang F; Wanninayaka A; Carnell M; Hardeman EC; Jin D; Gunning PW, 2023, 'Cortical tension drug screen links mitotic spindle integrity to Rho pathway', Current Biology, 33, pp. 4458 - 4469.e4, http://dx.doi.org/10.1016/j.cub.2023.09.022

Machet J; Park M; Richardson A; Carnell M; Mouat MA; Smith NJ; Turner N; Cochran BJ; Rye KA; Di Girolamo N, 2023, 'Type 2 diabetes influences intraepithelial corneal nerve parameters and corneal stromal-epithelial nerve penetration sites', Journal of Diabetes Investigation, 14, pp. 591 - 601, http://dx.doi.org/10.1111/jdi.13974

Wong SL; Awatade NT; Astore MA; Allan KM; Carnell MJ; Slapetova I; Chen PC; Setiadi J; Pandzic E; Fawcett LK; Widger JR; Whan RM; Griffith R; Ooi CY; Kuyucak S; Jaffe A; Waters SA, 2022, 'Molecular Dynamics and Theratyping in Airway and Gut Organoids Reveal R352Q-CFTR Conductance Defect', American Journal of Respiratory Cell and Molecular Biology, 67, pp. 99 - 111, http://dx.doi.org/10.1165/rcmb.2021-0337OC

Wong SL; Awatade NT; Astore MA; Allan KM; Carnell MJ; Slapetova I; Chen PC; Capraro A; Fawcett LK; Whan RM; Griffith R; Ooi CY; Kuyucak S; Jaffe A; Waters SA, 2022, 'Molecular dynamics and functional characterization of I37R-CFTR lasso mutation provide insights into channel gating activity', iScience, 25, pp. 103710, http://dx.doi.org/10.1016/j.isci.2021.103710

Tuck H; Park M; Carnell M; Machet J; Richardson A; Jukic M; Di Girolamo N, 2021, 'Neuronal-epithelial cell alignment: A determinant of health and disease status of the cornea', Ocular Surface, 21, pp. 257 - 270, http://dx.doi.org/10.1016/j.jtos.2021.03.007

Tavassoli H; Rorimpandey P; Kang YC; Carnell M; Brownlee C; Pimanda JE; Chan PPY; Chandrakanthan V, 2021, 'Label-Free Isolation and Single Cell Biophysical Phenotyping Analysis of Primary Cardiomyocytes Using Inertial Microfluidics', Small, 17, http://dx.doi.org/10.1002/smll.202006176

La T; Chen S; Guo T; Zhao XH; Teng L; Li D; Carnell M; Zhang YY; Feng YC; Cole N; Brown AC; Zhang D; Dong Q; Wang JY; Cao H; Liu T; Thorne RF; Shao FM; Zhang XD; Jin L, 2021, 'Visualization of endogenous p27 and Ki67 reveals the importance of a c-Myc-driven metabolic switch in promoting survival of quiescent cancer cells', Theranostics, 11, pp. 9605 - 9622, http://dx.doi.org/10.7150/THNO.63763

Tavassoli H; Rorimpandey P; Kang YC; Carnell M; Brownlee C; Pimanda JE; Chan PPY; Chandrakanthan V, 2021, 'Heart on A Chip: Label‐Free Isolation and Single Cell Biophysical Phenotyping Analysis of Primary Cardiomyocytes Using Inertial Microfluidics (Small 8/2021)', Small, 17, http://dx.doi.org/10.1002/smll.202170034

Wang Y; Stear JH; Swain A; Xu X; Bryce NS; Carnell M; Alieva IB; Dugina VB; Cripe TP; Stehn J; Hardeman EC; Gunning PW, 2020, 'Drug targeting the actin cytoskeleton potentiates the cytotoxicity of low dose vincristine by abrogating actin-mediated repair of spindle defects', Molecular Cancer Research, 18, pp. 1074 - 1087, http://dx.doi.org/10.1158/1541-7786.MCR-19-1122

Tavassoli H; Rorimpandey P; Kang YC; Carnell M; Brownlee C; Pimanda J; Chan PPY; Chandrakanthan V, 2020, 'Label-free Isolation and Single Cell Biophysical Phenotyping Analysis of Primary Cardiomyocytes Using Inertial Microfluidics', , http://dx.doi.org/10.1101/2020.08.31.243592

Redpath GMI; Ecker M; Kapoor-Kaushik N; Vartoukian H; Carnell M; Kempe D; Biro M; Ariotti N; Rossy J; Kaushik N, 2019, 'Flotillins promote T cell receptor sorting through a fast Rab5–Rab11 endocytic recycling axis', Nature Communications, 10, pp. 4392, http://dx.doi.org/10.1038/s41467-019-12352-w

Compeer EB; Kraus F; Ecker M; Redpath G; Amiezer M; Rother N; Nicovich PR; Kapoor-Kaushik N; Deng Q; Samson GPB; Yang Z; Lou J; Carnell M; Vartoukian H; Gaus K; Rossy J, 2018, 'A mobile endocytic network connects clathrin-independent receptor endocytosis to recycling and promotes T cell activation', Nature Communications, 9, http://dx.doi.org/10.1038/s41467-018-04088-w

Chandrakanthan V; Yeola A; Kwan JC; Oliver RA; Qiao Q; Kang YC; Zarzour P; Beck D; Boelen L; Unnikrishnan A; Villanueva JE; Nunez AC; Knezevic K; Palu C; Nasrallah R; Carnell M; Macmillan A; Whan R; Yu Y; Hardy P; Grey ST; Gladbach A; Delerue F; Ittner L; Mobbs R; Walkley CR; Purton LE; Ward RL; Wong JWH; Hesson LB; Walsh W; Pimanda JE, 2016, 'Pdgf-ab and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cells', Proceedings of the National Academy of Sciences of the United States of America, 113, pp. E2306 - E2315, http://dx.doi.org/10.1073/pnas.1518244113

Colley B; Dederer V; Carnell M; Kjelleberg S; Rice SA; Klebensberger J, 2016, 'SiaA/D interconnects c-di-GMP and RsmA signaling to coordinate cellular aggregation of Pseudomonas aeruginosa in response to environmental conditions', Frontiers in Microbiology, 7, http://dx.doi.org/10.3389/fmicb.2016.00179

Carnell M; Macmillan A; Whan R, 2015, 'Fluorescence recovery after photobleaching (FRAP): Acquisition, analysis, and applications', Methods in Molecular Biology, 1232, pp. 255 - 271, http://dx.doi.org/10.1007/978-1-4939-1752-5_18

Pasquier E; Tuset MP; Sinnappan S; Carnell M; Macmillan A; Kavallaris M, 2015, 'γ-Actin plays a key role in endothelial cell motility and neovessel maintenance', Vascular Cell, 7, http://dx.doi.org/10.1186/s13221-014-0027-2

Park L; Thomason PA; Zech T; King JS; Veltman DM; Carnell M; Ura S; Machesky LM; Insall RH, 2013, 'Cyclical Action of the WASH Complex: FAM21 and Capping Protein Drive WASH Recycling, Not Initial Recruitment', DEVELOPMENTAL CELL, 24, pp. 169 - 181, http://dx.doi.org/10.1016/j.devcel.2012.12.014

Zech T; Calaminus SDJ; Caswell P; Spence HJ; Carnell M; Insall RH; Norman J; Machesky LM, 2011, 'The Arp2/3 activator WASH regulates α5β1-integrin-mediated invasive migration', Journal of Cell Science, 124, pp. 3753 - 3759, http://dx.doi.org/10.1242/jcs.080986

Carnell M; Zech T; Calaminus SD; Ura S; Hagedorn M; Johnston SA; May RC; Soldati T; Machesky LM; Insall RH, 2011, 'Actin polymerization driven by WASH causes V-ATPase retrieval and vesicle neutralization before exocytosis', Journal of Cell Biology, 193, pp. 831 - 839, http://dx.doi.org/10.1083/jcb.201009119

Carnell MJ; Insall RH, 2011, 'Actin on disease - Studying the pathobiology of cell motility using Dictyostelium discoideum', Seminars in Cell and Developmental Biology, 22, pp. 82 - 88, http://dx.doi.org/10.1016/j.semcdb.2010.12.003

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