By Dr Sara Litwak

Journal articles

So M; Waibel M; Couper JJ; Cameron FJ; MacIsaac RJ; Atlas G; Gorelik A; Vogrin S; Litwak S; Sanz-Villanueva L; Trivedi P; Harbison JE; Hall C; Krishnamurthy B; Colman PG; Harrison LC; Thomas HE; Kay TWH; Wentworth JM; Kay T; Thomas H; So M; Krishnamurthy B; Waibel M; Doyle M; Mannering S; Litwak S; Sanz-Villanueva L; Catterall T; Trivedi P; Brodnicki T; Woods K; Kuspira L; Kruger N; Gorelik A; Wentworth J; Hall C; Gonzalez V; Kludas R; Healy F; Redl L; Harrison L; Colman P; MacIsaac R; Masterton M; Mulrooney E; Keenan J; Cameron F; Atlas G; Gebert R; Nip WF; Lee S; Couper J; Harbison J; Herewane K; Anh Huynh DH; Hall M; Anderson M; Craig M; Sasadeusz J; Mynhardt S; Koopman-Daemen A; Murphy K; Mwangi M, 2026, 'β-Cell Function and Diabetes Outcomes 1 Year After Stopping Oral Baricitinib Immunotherapy for Type 1 Diabetes.', Diabetes Care, http://dx.doi.org/10.2337/dc26-1072

Waibel M; Wentworth JM; So M; Couper JJ; Cameron FJ; Macisaac RJ; Atlas G; Gorelik A; Litwak S; Sanz-Villanueva L; Trivedi P; Ahmed S; Martin FJ; Doyle ME; Harbison JE; Hall C; Krishnamurthy B; Colman PG; Harrison LC; Thomas HE; Kay TWH, 2023, 'Baricitinib and β-Cell Function in Patients with New-Onset Type 1 Diabetes', New England Journal of Medicine, 389, pp. 2140 - 2150, http://dx.doi.org/10.1056/NEJMoa2306691

Ge T; Phung AL; Jhala G; Trivedi P; Principe N; De George DJ; Pappas EG; Litwak S; Sanz-Villanueva L; Catterall T; Fynch S; Boon L; Kay TW; Chee J; Krishnamurthy B; Thomas HE, 2022, 'Diabetes induced by checkpoint inhibition in nonobese diabetic mice can be prevented or reversed by a JAK1/JAK2 inhibitor', Clinical and Translational Immunology, 11, http://dx.doi.org/10.1002/cti2.1425

Eriksson M; Litwak SA; Yun Y; Stanley WJ; Thorn P; Ahlgren U; Gurzov EN, 2021, 'Insulin-Binding Peptide Probes Provide a Novel Strategy for Pancreatic β-Cell Imaging', Molecular Pharmaceutics, 18, pp. 4428 - 4436, http://dx.doi.org/10.1021/acs.molpharmaceut.1c00616

Schaschkow A; Pang L; Vandenbempt V; Elvira B; Litwak SA; Vekeriotaite B; Maillard E; Vermeersch M; Paula FMM; Pinget M; Perez-Morga D; Gough DJ; Gurzov EN, 2021, 'STAT3 Regulates Mitochondrial Gene Expression in Pancreatic β-Cells and Its Deficiency Induces Glucose Intolerance in Obesity', Diabetes, 70, pp. 2026 - 2041, http://dx.doi.org/10.2337/DB20-1222

Ge T; Jhala G; Fynch S; Akazawa S; Litwak S; Pappas EG; Catterall T; Vakil I; Long AJ; Olson LM; Krishnamurthy B; Kay TW; Thomas HE, 2020, 'The JAK1 Selective Inhibitor ABT 317 Blocks Signaling Through Interferon-γ and Common γ Chain Cytokine Receptors to Reverse Autoimmune Diabetes in NOD Mice', Frontiers in Immunology, 11, http://dx.doi.org/10.3389/fimmu.2020.588543

Litwak SA; Pang L; Galic S; Igoillo-Esteve M; Stanley WJ; Turatsinze JV; Loh K; Thomas HE; Sharma A; Trepo E; Moreno C; Gough DJ; Eizirik DL; De Haan JB; Gurzov EN, 2017, 'JNK activation of BIM promotes hepatic oxidative stress, steatosis, and insulin resistance in obesity', Diabetes, 66, pp. 2973 - 2986, http://dx.doi.org/10.2337/db17-0348

Enriori PJ; Chen W; Garcia-Rudaz MC; Grayson BE; Evans AE; Comstock SM; Gebhardt U; Müller HL; Reinehr T; Henry BA; Brown RD; Bruce CR; Simonds SE; Litwak SA; McGee SL; Luquet S; Martinez S; Jastroch M; Tschöp MH; Watt MJ; Clarke IJ; Roth CL; Grove KL; Cowley MA, 2016, 'α-Melanocyte stimulating hormone promotes muscle glucose uptake via melanocortin 5 receptors', Molecular Metabolism, 5, pp. 807 - 822, http://dx.doi.org/10.1016/j.molmet.2016.07.009

Møller CL; Kjøbsted R; Enriori PJ; Jensen TE; Garcia-Rudaz C; Litwak SA, 2016, 'Correction: Α-MSH stimulates glucose uptake in mouse muscle and phosphorylates RabGTPase-activating protein TBC1D1 independently of AMPK (PLoS ONE(2016)11:7 (e0157027)Doi: 10.1371/journal.pone.0157027)', Plos One, 11, http://dx.doi.org/10.1371/journal.pone.0161047

Møller CL; Kjøbsted R; Enriori PJ; Jensen TE; Garcia-Rudaz C; Litwak SA; Raun K; Wojtaszewski J; Wulff BS; Cowley MA, 2016, 'α-MSH stimulates glucose uptake in mouse muscle and phosphorylates Rab-GTPase-activating protein TBC1D1 independently of AMPK', Plos One, 11, http://dx.doi.org/10.1371/journal.pone.0157027

Litwak SA; Loh K; Stanley WJ; Pappas EG; Wali JA; Selck C; Strasser A; Thomas HE; Gurzov EN, 2016, 'P53-upregulated-modulator-of-apoptosis (PUMA) deficiency affects food intake but does not impact on body weight or glucose homeostasis in diet-induced obesity.', Scientific Reports, 6, http://dx.doi.org/10.1038/srep23802

Gurzov EN; Wang B; Pilkington EH; Chen P; Kakinen A; Stanley WJ; Litwak SA; Hanssen EG; Davis TP; Ding F; Ke PC, 2016, 'Inhibition of hIAPP Amyloid Aggregation and Pancreatic β-Cell Toxicity by OH-Terminated PAMAM Dendrimer', Small, 12, pp. 1615 - 1626, http://dx.doi.org/10.1002/smll.201502317

Pilkington EH; Gurzov EN; Kakinen A; Litwak SA; Stanley WJ; Davis TP; Ke PC, 2016, 'Pancreatic β-Cell Membrane Fluidity and Toxicity Induced by Human Islet Amyloid Polypeptide Species', Scientific Reports, 6, http://dx.doi.org/10.1038/srep21274

Nedumpully-Govindan P; Gurzov EN; Chen P; Pilkington EH; Stanley WJ; Litwak SA; Davis TP; Ke PC; Ding F, 2016, 'Graphene oxide inhibits hIAPP amyloid fibrillation and toxicity in insulin-producing NIT-1 cells', Physical Chemistry Chemical Physics, 18, pp. 94 - 100, http://dx.doi.org/10.1039/c5cp05924k

Stanley WJ; Litwak SA; Quah HS; Tan SM; Kay TWH; Tiganis T; De Haan JB; Thomas HE; Gurzov EN, 2015, 'Inactivation of protein tyrosine phosphatases enhances interferon signaling in pancreatic islets', Diabetes, 64, pp. 2489 - 2496, http://dx.doi.org/10.2337/db14-1575

Litwak SA; Wali JA; Pappas EG; Saadi H; Stanley WJ; Varanasi LC; Kay TWH; Thomas HE; Gurzov EN, 2015, 'Lipotoxic Stress Induces Pancreatic β-Cell Apoptosis through Modulation of Bcl-2 Proteins by the Ubiquitin-Proteasome System', Journal of Diabetes Research, 2015, http://dx.doi.org/10.1155/2015/280615

Litwak SA; Wilson JL; Chen W; Garcia-Rudaz C; Khaksari M; Cowley MA; Enriori PJ, 2014, 'Estradiol prevents fat accumulation and overcomes leptin resistance in female high-fat diet mice', Endocrinology United States, 155, pp. 4447 - 4460, http://dx.doi.org/10.1210/en.2014-1342

Litwak SA; Payne NL; Campanale N; Ozturk E; Lee JY; Petratos S; Siatskas C; Bakhuraysah M; Bernard CCA, 2013, 'Nogo-receptor 1 deficiency has no influence on immune cell repertoire or function during experimental autoimmune encephalomyelitis', Plos One, 8, http://dx.doi.org/10.1371/journal.pone.0082101

Beutner C; Lepperhof V; Dann A; Linnartz-Gerlach B; Litwak S; Napoli I; Prinz M; Neumann H, 2013, 'Engineered stem cell-derived microglia as therapeutic vehicle for experimental autoimmune encephalomyelitis', Gene Therapy, 20, pp. 797 - 806, http://dx.doi.org/10.1038/gt.2012.100

Petratos S; Ozturk E; Azari MF; Kenny R; Young Lee J; Magee KA; Harvey AR; McDonald C; Taghian K; Moussa L; Mun Aui P; Siatskas C; Litwak S; Fehlings MG; Strittmatter SM; Bernard CCA, 2012, 'Limiting multiple sclerosis related axonopathy by blocking Nogo receptor and CRMP-2 phosphorylation', Brain, 135, pp. 1794 - 1818, http://dx.doi.org/10.1093/brain/aws100

Short MA; Campanale N; Litwak S; Bernard CCA, 2011, 'Quantitative and phenotypic analysis of bone marrow-derived cells in the intact and inflamed central nervous system', Cell Adhesion and Migration, 5, pp. 373 - 381, http://dx.doi.org/10.4161/cam.5.5.17948

Schwarting S; Litwak S; Hao W; Bähr M; Weise J; Neumann H, 2008, 'Hematopoietic stem cells reduce postischemic inflammation and ameliorate ischemic brain injury', Stroke, 39, pp. 2867 - 2875, http://dx.doi.org/10.1161/STROKEAHA.108.513978

Fischer YH; Miletic H; Giroglu T; Litwak S; Stenzel W; Neumann H; von Laer D, 2007, 'A retroviral packaging cell line for pseudotype vectors based on glioma-infiltrating progenitor cells', Journal of Gene Medicine, 9, pp. 335 - 344, http://dx.doi.org/10.1002/jgm.1032

Miletic H; Fischer Y; Litwak S; Giroglou T; Waerzeggers Y; Winkeler A; Li H; Himmelreich U; Lange C; Stenzel W; Deckert M; Neumann H; Jacobs AH; von Laer D, 2007, 'Bystander killing of malignant glioma by bone marrow-derived tumor-infiltrating progenitor cells expressing a suicide gene', Molecular Therapy, 15, pp. 1373 - 1381, http://dx.doi.org/10.1038/sj.mt.6300155

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