By Dr Steven Thomas Leach

Books

Leach ST; Collins AM, 2010, The hepatic mast cell. In intestinal hypersensitivity and intestinal nematode infection, Lambert Academic Publishing, Koln, Germany

Book Chapters

Leach ST; Day AS, 2019, 'Enzyme-linked immunosorbent assay to measure S100A12 in fecal samples of children and adults', in Methods in Molecular Biology, Humana Press, New York, pp. 755 - 761, http://dx.doi.org/10.1007/978-1-4939-9030-6_47

Journal articles

Chatterjee S; Leach ST; Lui K; Mishra A, 2024, 'Symbiotic symphony: Understanding host-microbiota dialogues in a spatial context', Seminars in Cell and Developmental Biology, 161-162, pp. 22 - 30, http://dx.doi.org/10.1016/j.semcdb.2024.03.001

Katsoudas N; Tavakoli P; Wu N; Shapiro A; Leach ST; Williams AJ; Paramsothy R; Ghaly S; Connor SJ; Samocha-Bonet D; Lambert K; Hold GL, 2024, 'Dietary Emulsifier Exposure in People with Inflammatory Bowel Disease Compared with Healthy Controls: Is There a Cause for Concern?', Inflammatory Bowel Diseases, 30, pp. 1241 - 1250, http://dx.doi.org/10.1093/ibd/izad318

Tang TC; Leach ST; Krishnan U, 2024, 'Proton pump inhibitors, antibiotics, and atopy increase the risk of eosinophilic esophagitis in children with esophageal atresia', Journal of Pediatric Gastroenterology and Nutrition, 78, pp. 1317 - 1328, http://dx.doi.org/10.1002/jpn3.12129

Traini I; Chan SY; Menzies J; Hughes J; Coffey MJ; McKay IR; Ooi CY; Leach ST; Krishnan U, 2024, 'Intestinal dysbiosis and inflammation in children with repaired esophageal atresia', Journal of Pediatric Gastroenterology and Nutrition, 78, pp. 43 - 51, http://dx.doi.org/10.1002/jpn3.12053

Krishnan U; Tang TC; Coffey MJ; Leach ST, 2024, 'Reply to “Proton pump inhibitors and esophageal atresia: Too early to change clinical practice”', Journal of Pediatric Gastroenterology and Nutrition, http://dx.doi.org/10.1002/jpn3.12374

Leach ST, 2024, 'Role of Probiotics and Prebiotics in Gut Symbiosis', Nutrients, 16, http://dx.doi.org/10.3390/nu16020238

Dissanayake RY; Yuan H; Coffey MJ; Traini I; Chan SY; Menzies J; Hughes J; McKay I; van Dorst JM; Leach ST; Chee OY; Krishnan U, 2024, '343 ARE AIRWAY MICROBIOTA AND INFLAMMATION IN CHILDREN WITH ESOPHAGEAL ATRESIA RELATED TO REFLUX ASPIRATION?', Gastroenterology, 166, pp. S - 80, http://dx.doi.org/10.1016/s0016-5085(24)00681-4

Wong PY; Yip C; Lemberg DA; Day AS; Leach ST, 2023, 'Evolution of a Pathogenic Microbiome', Journal of Clinical Medicine, 12, http://dx.doi.org/10.3390/jcm12227184

Menzies J; Sundararaj A; Cardamone M; McHarg A; Leach S; Krishnan U, 2023, 'Ketogenic Diets in Children With Intractable Epilepsy and its Effects on Gastrointestinal Function, Gut Microbiome, Inflammation, and Quality of Life', Journal of Pediatric Gastroenterology and Nutrition, 77, pp. 679 - 685, http://dx.doi.org/10.1097/MPG.0000000000003928

Lopez RN; Leach ST; Bowcock N; Coker E; Shapiro AJ; Day AS; Lemberg DA, 2023, 'Differences in Gut Microbiome Profile between Healthy Children and Children with Inflammatory Bowel Disease and/or Autoimmune Liver Disease: A Case-Control Study', Pathogens, 12, http://dx.doi.org/10.3390/pathogens12040585

Mah C; Jayawardana T; Leong G; Koentgen S; Lemberg D; Connor SJ; Rokkas T; Grimm MC; Leach ST; Hold GL, 2023, 'Assessing the Relationship between the Gut Microbiota and Inflammatory Bowel Disease Therapeutics: A Systematic Review', Pathogens, 12, http://dx.doi.org/10.3390/pathogens12020262

Makeyeva Y; Leach ST; Ryugo DK, 2023, 'Mast cells in the Milieu: A comparative study in the tongue and liver', Proceedings of the Shevchenko Scientific Society. Medical Sciences, 72, http://dx.doi.org/10.25040/NTSH2023.02.10

Tang T; Leach ST; Krishnan U, 2022, '283. DOES PROTON PUMP INHIBITOR EXPOSURE INCREASE THE RISK OF DEVELOPING EOSINOPHILIC ESOPHAGITIS IN CHILDREN WITH ESOPHAGEAL ATRESIA?', Diseases of the Esophagus, 35, http://dx.doi.org/10.1093/dote/doac051.283

Volkers AG; Appleton L; Gearry RB; Frampton CM; de Voogd FAE; Peters van Ton AM; Leach ST; Lemberg DA; Day AS, 2022, 'Fecal Calprotectin, Chitinase 3-Like-1, S100A12 and Osteoprotegerin as Markers of Disease Activity in Children with Crohn’s Disease', Gastrointestinal Disorders, 4, pp. 180 - 189, http://dx.doi.org/10.3390/gidisord4030017

Chandrasekar N; Dehlsen K; Leach ST; Krishnan U, 2022, 'Blenderised Tube Feeds vs. Commercial Formula: Which Is Better for Gastrostomy-Fed Children?', Nutrients, 14, http://dx.doi.org/10.3390/nu14153139

Traini I; Chan SY; Menzies J; Hughes J; Coffey MJ; Katz T; McKay IR; Ooi CY; Leach ST; Krishnan U, 2022, 'Evaluating the Dietary Intake of Children with Esophageal Atresia: A Prospective, Controlled, Observational Study', Journal of Pediatric Gastroenterology and Nutrition, 75, pp. 221 - 226, http://dx.doi.org/10.1097/MPG.0000000000003498

Wong E; Lui K; Day AS; Leach ST, 2022, 'Manipulating the neonatal gut microbiome: current understanding and future perspectives', Archives of Disease in Childhood: Fetal and Neonatal Edition, 107, pp. F346 - F350, http://dx.doi.org/10.1136/archdischild-2021-321922

Lu LDW; Singh H; Castaño-Rodríguez N; Leach ST; Riordan SM; Tedla N; Krishnan U; Kaakoush NO, 2022, 'Changes to the upper gastrointestinal microbiotas of children with reflux oesophagitis and oesophageal metaplasia', Microbial Genomics, 8, http://dx.doi.org/10.1099/mgen.0.000870

McHarg AS; Leach S, 2022, 'The role of the gut microbiome in paediatric irritable bowel syndrome', AIMS Microbiology, 8, pp. 454 - 469, http://dx.doi.org/10.3934/microbiol.2022030

MAKEYEVA Y; NICOL C; LEACH ST; De GRAAF SP; LEDGER WL; RYUGO DK, 2022, 'Immunolocalisation of Olfactory Signalling Molecules in Spermatozoa', Fertility & Reproduction, 04, pp. 196 - 196, http://dx.doi.org/10.1142/s2661318222741078

Chandrasekar N; Dehlsen K; Leach ST; Krishnan U, 2021, 'Exploring Clinical Outcomes and Feasibility of Blended Tube Feeds in Children', Journal of Parenteral and Enteral Nutrition, 45, pp. 685 - 698, http://dx.doi.org/10.1002/jpen.2062

Williams AJ; Paramsothy R; Wu N; Ghaly S; Leach S; Paramsothy S; Corte C; O'Brien C; Burke C; Wark G; Samocha-Bonet D; Lambert K; Ahlenstiel G; Wasinger V; Dutt S; Pavli P; Grimm M; Lemberg D; Connor S; Leong R; Hold G, 2021, 'Australia IBD Microbiome (AIM) Study: Protocol for a multicentre longitudinal prospective cohort study', BMJ Open, 11, http://dx.doi.org/10.1136/bmjopen-2020-042493

Krishnan U; Singh H; Tedla N; Leach ST; Kaakoush NO, 2020, 'Presence of gastric pepsinogen in the trachea is associated with altered inflammation and microbial composition', Infection and Immunity, 88, http://dx.doi.org/10.1128/IAI.00455-20

Ali F; Lui K; Wang A; Day AS; Leach ST, 2020, 'The perinatal period, the developing intestinal microbiome and inflammatory bowel diseases: What links early life events with later life disease?', Journal of the Royal Society of New Zealand, 50, pp. 371 - 383, http://dx.doi.org/10.1080/03036758.2019.1706586

Leach ST; Day AS; Messenger R; Walters TD; Navas-López VM; Sladek M; Brückner A; Yerushalmi B; Saeed S; Otley A; Mack D; Gavish M; Turner D; Griffiths AM; Lemberg DA, 2020, 'Fecal Markers of Inflammation and Disease Activity in Pediatric Crohn Disease: Results from the ImageKids Study', Journal of Pediatric Gastroenterology and Nutrition, 70, pp. 580 - 585, http://dx.doi.org/10.1097/MPG.0000000000002615

Traini I; Menzies J; Hughes J; Leach ST; Krishnan U, 2020, 'Oesophageal atresia: The growth gap', World Journal of Gastroenterology, 26, pp. 1262 - 1272, http://dx.doi.org/10.3748/WJG.V26.I12.1262

Upendran Y; Leach ST; Singh H; McBride J; Thomas PS; Belessis Y; Krishnan U, 2020, 'Pepsin as a Marker of Reflux Aspiration in Children With Esophageal Atresia: A Pilot Study', Frontiers in Pediatrics, 8, pp. 94, http://dx.doi.org/10.3389/fped.2020.00094

Traini I; Menzies J; Hughes J; Katz T; Coffey MJ; Ooi CY; Leach ST; Krishnan U; the EARTHRGOBO, 2020, '307 LOOKING BEYOND THE ESOPHAGUS: INVESTIGATING THE INTESTINAL MICROBIOTA AND INFLAMMATION IN CHILDREN WITH REPAIRED ESOPHAGEAL ATRESIA', Gastroenterology, 158, http://dx.doi.org/10.1016/s0016-5085(20)34438-3

Traini I; Menzies J; Hughes J; Katz T; Coffey MJ; Ooi CY; Leach ST; Krishnan U; Group EARTHR, 2020, 'Mo2000 FOOD FOR THOUGHT: DIET, DYSPHAGIA AND GROWTH IN CHILDREN WITH REPAIRED ESOPHAGEAL ATRESIA', Gastroenterology, 158, pp. S - 1575, http://dx.doi.org/10.1016/s0016-5085(20)34618-7

Lum A; Wakefield CE; Donnan B; Burns MA; Fardell JE; Jaffe A; Kasparian NA; Kennedy SE; Leach ST; Lemberg DA; Marshall GM, 2019, 'Facilitating engagement with school in students with chronic illness through positive education: A mixed-methods comparison study', School Psychology, 34, pp. 677 - 686, http://dx.doi.org/10.1037/spq0000315

Lum A; Wakefield CE; Donnan B; Burns MA; Fardell JE; Jaffe A; Kasparian NA; Kennedy SE; Leach ST; Lemberg DA; Marshall GM, 2019, 'School students with chronic illness have unmet academic, social, and emotional school needs', School Psychology, 34, pp. 627 - 636, http://dx.doi.org/10.1037/spq0000311

Thurgate LE; Lemberg DA; Day AS; Leach ST, 2019, 'An overview of inflammatory bowel disease unclassified in children', Inflammatory Intestinal Diseases, 4, pp. 97 - 103, http://dx.doi.org/10.1159/000501519

Krishnan U; Singh H; Kaakoush N; Leach S, 2019, 'DOZ047.18: Diagnosing reflux aspiration in esophageal atresia: role of microbiome and pepsin', Diseases of the Esophagus, 32, http://dx.doi.org/10.1093/dote/doz047.18

Day AS; Ho SSC; Leach ST, 2019, 'Letter to the Editor Re: Serum Calprotectin in Adolescents with Inflammatory Bowel Disease', Journal of Pediatric Gastroenterology and Nutrition, 68, pp. e109, http://dx.doi.org/10.1097/MPG.0000000000002345

Volkers A; Appleton L; Leach ST; Lemberg D; Day AS, 2019, 'Sa1761 – Chitinase 3-Like-1 Protein: A Novel Biomarker of Disease Activity and Risk of Relapse in Children with Inflammatory Bowel Disease', Gastroenterology, 156, pp. S - 391, http://dx.doi.org/10.1016/s0016-5085(19)37828-x

Weinstein-Nakar I; Focht G; Church P; Walters TD; Abitbol G; Anupindi S; Berteloot L; Hulst JM; Ruemmele F; Lemberg DA; Leach ST; Cytter R; Greer ML; Griffiths AM; Turner D, 2018, 'Associations Among Mucosal and Transmural Healing and Fecal Level of Calprotectin in Children With Crohn's Disease', Clinical Gastroenterology and Hepatology, 16, pp. 1089 - 1097.e4, http://dx.doi.org/10.1016/j.cgh.2018.01.024

Gan LL; Lum A; Wakefield CE; Donnan BM; Marshall GM; Burns MA; Jaffe A; Leach S; Lemberg DA; Fardell JE, 2018, 'The School Experiences of Siblings of Children with Chronic Illness: Australian Parents' Perceptions', Educational and Developmental Psychologist, 35, pp. 36 - 50, http://dx.doi.org/10.1017/edp.2018.3

Galgut BJ; Lemberg DA; Day AS; Leach ST, 2018, 'The value of fecal markers in predicting relapse in inflammatory bowel diseases', Frontiers in Pediatrics, 5, pp. 292, http://dx.doi.org/10.3389/fped.2017.00292

Garg M; Leach ST; Pang T; Needham B; Coffey MJ; Katz T; Strachan R; Widger J; Field P; Belessis Y; Chuang S; Day AS; Jaffe A; Ooi CY, 2018, 'Age-related levels of fecal M2-pyruvate kinase in children with cystic fibrosis and healthy children 0 to 10 years old', Journal of Cystic Fibrosis, 17, pp. 109 - 113, http://dx.doi.org/10.1016/j.jcf.2017.07.011

Garg M; Leach ST; Day AS; Ooi CY, 2018, 'Fecal calprotectin concentrations in young children with cystic fibrosis: Authors response', Journal of Cystic Fibrosis, 17, pp. e10 - e11, http://dx.doi.org/10.1016/j.jcf.2017.10.012

Cone S; Ooi CY; Coffey M; Larkin G; Leach ST; Poulton C, 2018, 'Mo2024 - Functional Dysbiosis in Children with Irritable Bowel Syndrome', Gastroenterology, 154, pp. S - 883, http://dx.doi.org/10.1016/s0016-5085(18)32985-8

Aggarwal V; Day AS; Connor S; Leach ST; Brown G; Singh R; Friedman A; Zekry A; Craig PI, 2017, 'Role of capsule endoscopy and fecal biomarkers in small-bowel Crohn's disease to assess remission and predict relapse', Gastrointestinal Endoscopy, 86, pp. 1070 - 1078, http://dx.doi.org/10.1016/j.gie.2017.09.011

Holtman GA; Lisman-van Leeuwen Y; Day AS; Fagerberg UL; Henderson P; Leach ST; Perminow G; Mack D; Van Rheenen PF; Van De Vijver E; Wilson DC; Reitsma JB; Berger MY, 2017, 'Use of laboratory markers in addition to symptoms for diagnosis of inflammatory bowel disease in children: A meta-analysis of individual patient data', JAMA Pediatrics, 171, pp. 984 - 991, http://dx.doi.org/10.1001/jamapediatrics.2017.1736

Day AS; Leach ST; Lemberg DA, 2017, 'An update on diagnostic and prognostic biomarkers in inflammatory bowel disease', Expert Review of Molecular Diagnostics, 17, pp. 835 - 843, http://dx.doi.org/10.1080/14737159.2017.1364160

Garg M; Leach ST; Coffey MJ; Katz T; Strachan R; Pang T; Needham B; Lui K; Ali F; Day AS; Appleton L; Moeeni V; Jaffe A; Ooi CY, 2017, 'Age-dependent variation of fecal calprotectin in cystic fibrosis and healthy children', Journal of Cystic Fibrosis, 16, pp. 631 - 636, http://dx.doi.org/10.1016/j.jcf.2017.03.010

Day AS; Mylvaganam G; Shalloo N; Clarkson C; Leach ST; Lemberg DA, 2017, 'Assessment of disease-specific knowledge in Australian children with inflammatory bowel disease and their parents', Journal of Paediatrics and Child Health, 53, pp. 778 - 781, http://dx.doi.org/10.1111/jpc.13544

Luo A; Leach ST; Barres R; Hesson LB; Grimm MC; Simar D, 2017, 'The microbiota and epigenetic regulation of t helper 17/regulatory T cells: In search of a balanced immune system', Frontiers in Immunology, 8, pp. 417, http://dx.doi.org/10.3389/fimmu.2017.00417

Alhagamhmad MH; Lemberg DA; Day AS; Tan LZ; Ooi CY; Krishnan U; Gupta N; Munday JS; Leach ST, 2017, 'Advancing nutritional therapy: A novel polymeric formulation attenuates intestinal inflammation in a murine colitis model and suppresses pro-inflammatory cytokine production in ex-vivo cultured inflamed colonic biopsies', Clinical Nutrition, 36, pp. 497 - 505, http://dx.doi.org/10.1016/j.clnu.2016.01.010

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