Dr Ulises Alejandro Aregueta Robles

Keywords

deep brain stimulation

Fields of Research (FoR)

Biomedical Engineering

Biography

Dr. Ulises A. Aregueta Robles is an early-mid career researcher working at the School of Biomedical Engineering. Majored in Biomedical Engineering, with a Masters in Biotechnology and a Ph.D. in Biomedical Engineering, Ulises leads the Tissue Engineering and Neuroprosthetics (TEN) Lab, which develops advanced in vitro human tissue models to support the testing, validation, and optimisation of medical devices and emerging biomedical technologies. Integrating hydrogel biomaterials, 3D bioprinting, microfluidics, and advanced biofabrication approaches, the lab engineers physiologically relevant tissue systems that replicate the complexity of native human tissues while reducing reliance on animal experimentation. A major research focus is the development of human cochlear and neural tissue models for evaluating neural prosthetic technologies, including cochlear implants and deep brain stimulation devices. The group’s interdisciplinary research spans tissue engineering, regenerative medicine, fibrosis modelling, cardiovascular and musculoskeletal tissue engineering, intelligent implant systems, and biomaterial-based wound healing therapies. Through collaborations with clinicians, engineers, academic institutions, and industry partners, including Cochlear Ltd., the TEN Lab aims to accelerate the translation of biomedical innovations into safer, more effective implantable technologies and regenerative therapies that improve patient outcomes.

My Research Activities

Development of advanced in vitro human tissue models for medical device testing and validation
Engineering physiologically relevant cochlear tissue models for cochlear implant research
Tissue engineering of fibrotic tissue models to study implant host responses
Design and fabrication of 3D bioprinted hydrogel tissue constructs
Development of temporal bone models for surgical training and cochlear electrode implantation studies
Engineering neural tissue structures using hydrogel biomaterials and stem cell-derived cells
Fabrication of tubular scaffolds for nerve and vascular tissue engineering applications
Development of cardiovascular tissue models for evaluating stent technologies
Engineering hydrogel-based tendon tissue scaffolds with physiologically relevant mechanical properties
Development of bioinks for advanced 3D bioprinting and tissue manufacturing applications
Creation of hydrogel-based microfluidic platforms for studying neuropathic pain mechanisms
Investigation of electrode degradation mechanisms in neural prosthetic devices
Development of electroactive and smart polymer coatings for implantable electrodes
Design of intelligent systems for monitoring and controlling electrode impedance in implantable devices
Development of biomaterial-based wound healing therapies for veterinary and agricultural applications