By Dr Yoshiro Okubo

Journal articles

Takahashi H; Matsui H; Camerer C; Takano H; Kodaka F; Ideno T; Okubo S; Takemura K; Arakawa R; Eguchi Y; Murai T; Okubo Y; Kato M; Ito H; Suhara T, 2010, 'Dopamine D1 receptors and nonlinear probability weighting in risky choice', Journal of Neuroscience, 30, pp. 16567 - 16572, http://dx.doi.org/10.1523/JNEUROSCI.3933-10.2010

Matsumoto R; Ito H; Takahashi H; Ando T; Fujimura Y; Nakayama K; Okubo Y; Obata T; Fukui K; Suhara T, 2010, 'Reduced gray matter volume of dorsal cingulate cortex in patients with obsessive-compulsive disorder: A voxel-based morphometric study', Psychiatry and Clinical Neurosciences, 64, pp. 541 - 547, http://dx.doi.org/10.1111/j.1440-1819.2010.02125.x

Karibe H; Arakawa R; Tateno A; Mizumura S; Okada T; Ishii T; Oshima K; Ohtsu M; Hasegawa I; Okubo Y, 2010, 'Regional cerebral blood flow in patients with orally localized somatoform pain disorder: A single photon emission computed tomography study', Psychiatry and Clinical Neurosciences, 64, pp. 476 - 482, http://dx.doi.org/10.1111/j.1440-1819.2010.02119.x

Arakawa R; Okumura M; Ito H; Takano A; Takahashi H; Takano H; Maeda J; Okubo Y; Suhara T, 2010, 'Positron emission tomography measurement of dopamine D2 receptor occupancy in the pituitary and cerebral cortex: Relation to antipsychotic-induced hyperprolactinemia', Journal of Clinical Psychiatry, 71, pp. 1131 - 1137, http://dx.doi.org/10.4088/JCP.08m04307yel

Koeda M; Tateno A; Ishizaka K; Saijo T; Okubo Y, 2010, 'Working memory processing for human voice perception in a patient with mild cognitive impairment: An fMRI study', Journal of Nippon Medical School, 77, pp. 188 - 189, http://dx.doi.org/10.1272/jnms.77.188

Takano A; Arakawa R; Ito H; Tateno A; Takahashi H; Matsumoto R; Okubo Y; Suhara T, 2010, 'Peripheral benzodiazepine receptors in patients with chronic schizophrenia: A PET study with [¹¹C]DAA1106', International Journal of Neuropsychopharmacology, 13, pp. 943 - 950, http://dx.doi.org/10.1017/S1461145710000313

Adachi N; Akanuma N; Ito M; Kato M; Hara T; Oana Y; Matsuura M; Okubo Y; Onuma T, 2010, 'Authors' reply', British Journal of Psychiatry, 197, pp. 76, http://dx.doi.org/10.1192/bjp.197.1.76

Saijo T; Takano A; Suhara T; Arakawa R; Okumura M; Ichimiya T; Ito H; Okubo Y, 2010, 'Effect of electroconvulsive therapy on 5-HT1A receptor binding in patients with depression: A PET study with [¹¹C]WAY 100635', International Journal of Neuropsychopharmacology, 13, pp. 785 - 791, http://dx.doi.org/10.1017/S1461145709991209

Takahashi H; Kato M; Sassa T; Shibuya T; Koeda M; Yahata N; Matsuura M; Asai K; Suhara T; Okubo Y, 2010, 'Functional deficits in the extrastriate body area during observation of sports-related actions in schizophrenia', Schizophrenia Bulletin, 36, pp. 642 - 647, http://dx.doi.org/10.1093/schbul/sbn132

Saijo T; Takano A; Suhara T; Arakawa R; Okumura M; Ichimiya T; Ito H; Okubo Y, 2010, 'Electroconvulsive therapy decreases dopamine D2 receptor binding in the anterior cingulate in patients with depression: A controlled study using positron emission tomography with radioligand [¹¹C]FLB 457', Journal of Clinical Psychiatry, 71, pp. 793 - 799, http://dx.doi.org/10.4088/JCP.08m04746blu

Arakawa R; Ito H; Okumura M; Takano A; Takahashi H; Takano H; Okubo Y; Suhara T, 2010, 'Extrastriatal dopamine D2 receptor occupancy in olanzapine-treated patients with schizophrenia', European Archives of Psychiatry and Clinical Neuroscience, 260, pp. 345 - 350, http://dx.doi.org/10.1007/s00406-009-0082-5

Ueda S; Koyama K; Okubo Y, 2010, 'Marked improvement of psychotic symptoms after electroconvulsive therapy in parkinson disease', Journal of ECT, 26, pp. 111 - 115, http://dx.doi.org/10.1097/YCT.0b013e3181c18a3d

Sekine M; Arakawa R; Ito H; Okumura M; Sasaki T; Takahashi H; Takano H; Okubo Y; Halldin C; Suhara T, 2010, 'Norepinephrine transporter occupancy by antidepressant in human brain using positron emission tomography with (S,S)-[¹⁸F]FMeNER-D 2', Psychopharmacology, 210, pp. 331 - 336, http://dx.doi.org/10.1007/s00213-010-1824-9

Ikeda Y; Yahata N; Takahashi H; Koeda M; Asai K; Okubo Y; Suzuki H, 2010, 'Cerebral activation associated with speech sound discrimination during the diotic listening task: An fMRI study', Neuroscience Research, 67, pp. 65 - 71, http://dx.doi.org/10.1016/j.neures.2010.02.006

Kosaka J; Takahashi H; Ito H; Takano A; Fujimura Y; Matsumoto R; Nozaki S; Yasuno F; Okubo Y; Kishimoto T; Suhara T, 2010, 'Decreased binding of [¹¹C]NNC112 and [¹¹C]SCH23390 in patients with chronic schizophrenia', Life Sciences, 86, pp. 814 - 818, http://dx.doi.org/10.1016/j.lfs.2010.03.018

Arakawa R; Ito H; Takano A; Okumura M; Takahashi H; Takano H; Okubo Y; Suhara T, 2010, 'Dopamine D2 receptor occupancy by perospirone: A positron emission tomography study in patients with schizophrenia and healthy subjects', Psychopharmacology, 209, pp. 285 - 290, http://dx.doi.org/10.1007/s00213-010-1783-1

Watari M; Hamazaki K; Hirata T; Hamazaki T; Okubo Y, 2010, 'Hostility of drug-free patients with schizophrenia and n-3 polyunsaturated fatty acid levels in red blood cells', Psychiatry Research, 177, pp. 22 - 26, http://dx.doi.org/10.1016/j.psychres.2010.02.016

Adachi N; Akanuma N; Ito M; Kato M; Hara T; Oana Y; Matsuura M; Okubo Y; Onuma T, 2010, 'Epileptic, organic and genetic vulnerabilities for timing of the development of interictal psychosis', British Journal of Psychiatry, 196, pp. 212 - 216, http://dx.doi.org/10.1192/bjp.bp.108.056721

Takahashi H; Takano H; Kodaka F; Arakawa R; Yamada M; Otsuka T; Hirano Y; Kikyo H; Okubo Y; Kato M; Obata T; Ito H; Suhara T, 2010, 'Contribution of dopamine D1 and D2 receptors to amygdala activity in human', Journal of Neuroscience, 30, pp. 3043 - 3047, http://dx.doi.org/10.1523/JNEUROSCI.5689-09.2010

Hirayasu Y; Kawanishi C; Yonemoto N; Ishizuka N; Okubo Y; Sakai A; Kishimoto T; Miyaoka H; Otsuka K; Kamijo Y; Matsuoka Y; Aruga T, 2009, 'A randomized controlled multicenter trial of post-suicide attempt case management for the prevention of further attempts in Japan (ACTION-J)', BMC Public Health, 9, http://dx.doi.org/10.1186/1471-2458-9-364

Arakawa R; Ichimiya T; Ito H; Takano A; Okumura M; Takahashi H; Takano H; Yasuno F; Kato M; Okubo Y; Suhara T, 2009, 'Increase in thalamic binding of [¹¹C]PE2I in patients with schizophrenia: A positron emission tomography study of dopamine transporter', Journal of Psychiatric Research, 43, pp. 1219 - 1223, http://dx.doi.org/10.1016/j.jpsychires.2009.04.009

Takahashi H; Ideno T; Okubo S; Matsui H; Takemura K; Matsuura M; Kato M; Okubo Y, 2009, 'Impact of changing the Japanese term for "schizophrenia" for reasons of stereotypical beliefs of schizophrenia in Japanese youth', Schizophrenia Research, 112, pp. 149 - 152, http://dx.doi.org/10.1016/j.schres.2009.03.037

Suzuki M; Takahashi S; Matsushima E; Tsunoda M; Kurachi M; Okada T; Hayashi T; Ishii Y; Morita K; Maeda H; Katayama S; Kawahara R; Otsuka T; Hirayasu Y; Sekine M; Okubo Y; Motoshita M; Ohta K; Uchiyama M; Kojima T, 2009, 'Exploratory eye movement dysfunction as a discriminator for schizophrenia: A large sample study using a newly developed digital computerized system', European Archives of Psychiatry and Clinical Neuroscience, 259, pp. 186 - 194, http://dx.doi.org/10.1007/s00406-008-0850-7

Hara K; Adachi N; Matsuura M; Hara T; Oana Y; Okubo Y; Muramatsu R; Kato M; Onuma T, 2009, 'Handedness in epilepsy patients with psychosis', Journal of the Japan Epilepsy Society, 26, pp. 403 - 410, http://dx.doi.org/10.3805/jjes.26.403

Nozaki S; Kato M; Takano H; Ito H; Takahashi H; Arakawa R; Okumura M; Fujimura Y; Matsumoto R; Ota M; Takano A; Otsuka A; Yasuno F; Okubo Y; Kashima H; Suhara T, 2009, 'Regional dopamine synthesis in patients with schizophrenia using L-[β-¹¹C]DOPA PET', Schizophrenia Research, 108, pp. 78 - 84, http://dx.doi.org/10.1016/j.schres.2008.11.006

Takahashi H; Kato M; Matsuura M; Mobbs D; Suhara T; Okubo Y, 2009, 'When your gain is my pain and your pain is my gain: Neural correlates of envy and schadenfreude', Science, 323, pp. 937 - 939, http://dx.doi.org/10.1126/science.1165604

Ito T; Okubo Y; Roth A, 2009, 'Efficacy of mirtazapine for appetite loss and nausea of the cancer patient - From clinical experience in Memorial Sloan-Kettering Cancer Center', Japanese Journal of Cancer and Chemotherapy, 36, pp. 623 - 625

Takahashi H; Kato M; Takano H; Arakawa R; Okumura M; Otsuka T; Kodaka F; Hayashi M; Okubo Y; Ito H; Suhara T, 2008, 'Differential contributions of prefrontal and hippocampal dopamine D 1 and D2 receptors in human cognitive functions', Journal of Neuroscience, 28, pp. 12032 - 12038, http://dx.doi.org/10.1523/JNEUROSCI.3446-08.2008

Okumura M; Arakawa R; Ito H; Seki C; Takahashi H; Takano H; Haneda E; Nakao R; Suzuki H; Suzuki K; Okubo Y; Suhara T, 2008, 'Quantitative analysis of NK1 receptor in the human brain using PET with¹⁸F-FE-SPA-RQ', Journal of Nuclear Medicine, 49, pp. 1749 - 1755, http://dx.doi.org/10.2967/jnumed.108.054353

Takahashi H; Kato M; Matsuura M; Koeda M; Yahata N; Suhara T; Okubo Y, 2008, 'Neural correlates of human virtue judgment', Cerebral Cortex, 18, pp. 1886 - 1891, http://dx.doi.org/10.1093/cercor/bhm214

Arakawa R; Okumura M; Ito H; Seki C; Takahashi H; Takano H; Nakao R; Suzuki K; Okubo Y; Halldin C; Suhara T, 2008, 'Quantitative analysis of norepinephrine transporter in the human brain using PET with (S,S)-¹⁸F-FMeNER-D2', Journal of Nuclear Medicine, 49, pp. 1270 - 1276, http://dx.doi.org/10.2967/jnumed.108.051292

Takahashi H; Fujimura Y; Hayashi M; Takano H; Kato M; Okubo Y; Kanno I; Ito H; Suhara T, 2008, 'Enhanced dopamine release by nicotine in cigarette smokers: A double-blind, randomized, placebo-controlled pilot study', International Journal of Neuropsychopharmacology, 11, pp. 413 - 417, http://dx.doi.org/10.1017/S1461145707008103

Takahashi H; Matsuura M; Koeda M; Yahata N; Suhara T; Kato M; Okubo Y, 2008, 'Brain activations during judgments of positive self-conscious emotion and positive basic emotion: Pride and joy', Cerebral Cortex, 18, pp. 898 - 903, http://dx.doi.org/10.1093/cercor/bhm120

Arakawa R; Ito H; Takano A; Takahashi H; Morimoto T; Sassa T; Ohta K; Kato M; Okubo Y; Suhara T, 2008, 'Dose-finding study of paliperidone ER based on striatal and extrastriatal dopamine D2 receptor occupancy in patients with schizophrenia', Psychopharmacology, 197, pp. 229 - 235, http://dx.doi.org/10.1007/s00213-007-1029-z

Takahashi H; Shibuya T; Kato M; Sassa T; Koeda M; Yahata N; Suhara T; Okubo Y, 2008, 'Enhanced activation in the extrastriate body area by goal-directed actions', Psychiatry and Clinical Neurosciences, 62, pp. 214 - 219, http://dx.doi.org/10.1111/j.1440-1819.2008.01757.x

Ikeda Y; Yahata N; Ito I; Nagano M; Toyota T; Yoshikawa T; Okubo Y; Suzuki H, 2008, 'Low serum levels of brain-derived neurotrophic factor and epidermal growth factor in patients with chronic schizophrenia', Schizophrenia Research, 101, pp. 58 - 66, http://dx.doi.org/10.1016/j.schres.2008.01.017

Adachi N; Hara T; Oana Y; Matsuura M; Okubo Y; Akanuma N; Ito M; Kato M; Onuma T, 2008, 'Difference in age of onset of psychosis between epilepsy and schizophrenia', Epilepsy Research, 78, pp. 201 - 206, http://dx.doi.org/10.1016/j.eplepsyres.2007.12.001

Asai Y; Takano A; Ito H; Okubo Y; Matsuura M; Otsuka A; Takahashi H; Ando T; Ito S; Arakawa R; Asai K; Suhara T, 2008, 'GABAA/Benzodiazepine receptor binding in patients with schizophrenia using [¹¹C]Ro15-4513, a radioligand with relatively high affinity for α5 subunit', Schizophrenia Research, 99, pp. 333 - 340, http://dx.doi.org/10.1016/j.schres.2007.10.014

Takahashi H; Kato M; Hayashi M; Okubo Y; Takano A; Ito H; Suhara T, 2007, 'Memory and frontal lobe functions; possible relations with dopamine D2 receptors in the hippocampus', NeuroImage, 34, pp. 1643 - 1649, http://dx.doi.org/10.1016/j.neuroimage.2006.11.008

Ito S; Suhara T; Ito H; Yasuno F; Ichimiya T; Takano A; Maehara T; Matsuura M; Okubo Y, 2007, 'Changes in central 5-HT1A receptor binding in mesial temporal epilepsy measured by positron emission tomography with [¹¹C]WAY100635', Epilepsy Research, 73, pp. 111 - 118, http://dx.doi.org/10.1016/j.eplepsyres.2006.09.003

Koeda M; Takahashi H; Yahata N; Matsuura M; Asai K; Okubo Y; Tanaka H, 2007, 'Neural responses to human voice andhemisphere dominance for lexical-semantic processing: An fMRI study', Methods of Information in Medicine, 46, pp. 247 - 250, http://dx.doi.org/10.1055/s-0038-1625416

Ishiwata K; Oda K; Sakata M; Kimura Y; Kawamura K; Oda K; Sasaki T; Naganawa M; Chihara K; Okubo Y; Ishii K, 2006, 'A feasibility study of [ ¹¹C]SA4503-PET for evaluating sigma 1 receptor occupancy by neuroleptics: The binding of haloperidol to sigma 1 and dopamine D 2-like receptors', Annals of Nuclear Medicine, 20, pp. 569 - 573, http://dx.doi.org/10.1007/BF03026824

Talvik M; Nordström AL; Okubo Y; Olsson H; Borg J; Halldin C; Farde L, 2006, 'Dopamine D2 receptor binding in drug-naïve patients with schizophrenia examined with raclopride-C11 and positron emission tomography', Psychiatry Research - Neuroimaging, 148, pp. 165 - 173, http://dx.doi.org/10.1016/j.pscychresns.2006.05.009

Takano A; Suhara T; Yasuno F; Suzuki K; Takahashi H; Morimoto T; Lee YJ; Kusuhara H; Sugiyama Y; Okubo Y, 2006, 'The antipsychotic sultopride is overdosed - A PET study of drug-induced receptor occupancy in comparison with sulpiride', International Journal of Neuropsychopharmacology, 9, pp. 539 - 545, http://dx.doi.org/10.1017/S1461145705006103

Takahashi H; Matsuura M; Yahata N; Koeda M; Suhara T; Okubo Y, 2006, 'Men and women show distinct brain activations during imagery of sexual and emotional infidelity', NeuroImage, 32, pp. 1299 - 1307, http://dx.doi.org/10.1016/j.neuroimage.2006.05.049

Koeda M; Takahashi H; Yahata N; Asai K; Okubo Y; Tanaka H, 2006, 'A functional MRI study: Cerebral laterality for lexical-semantic processing and human voice perception', American Journal of Neuroradiology, 27, pp. 1472 - 1479

Tanaka Y; Obata T; Sassa T; Yoshitome E; Asai Y; Ikehira H; Suhara T; Okubo Y; Nishikawa T, 2006, 'Quantitative magnetic resonance spectroscopy of schizophrenia: Relationship between decreased N -acetylaspartate and frontal lobe dysfunction', Psychiatry and Clinical Neurosciences, 60, pp. 365 - 372, http://dx.doi.org/10.1111/j.1440-1819.2006.01515.x

Koeda M; Takahashi H; Yahata N; Matsuura M; Asai K; Okubo Y; Tanaka H, 2006, 'Language Processing and Human Voice Perception in Schizophrenia: A Functional Magnetic Resonance Imaging Study', Biological Psychiatry, 59, pp. 948 - 957, http://dx.doi.org/10.1016/j.biopsych.2006.01.013

Takahashi H; Yahata N; Koeda M; Takano A; Asai K; Suhara T; Okubo Y, 2005, 'Effects of dopaminergic and serotonergic manipulation on emotional processing: A pharmacological fMRI study', NeuroImage, 27, pp. 991 - 1001, http://dx.doi.org/10.1016/j.neuroimage.2005.05.039

Yasuno F; Suhara T; Okubo Y; Ichimiya T; Takano A; Sudo Y; Inoue M, 2005, 'Abnormal effective connectivity of dopamine D2 receptor binding in schizophrenia', Psychiatry Research - Neuroimaging, 138, pp. 197 - 207, http://dx.doi.org/10.1016/j.pscychresns.2004.04.005

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