Select Publications
By Dr Ze Yan Yu
Journal articles
, 2022, 'Piezo1 is the cardiac mechanosensor that initiates the cardiomyocyte hypertrophic response to pressure overload in adult mice', Nature Cardiovascular Research, 1, pp. 577 - 591, http://dx.doi.org/10.1038/s44161-022-00082-0
, 2021, 'Modified N-linked glycosylation status predicts trafficking defective human Piezo1 channel mutations', Communications Biology, 4, http://dx.doi.org/10.1038/s42003-021-02528-w
, 2021, 'The ca2+-activated cation channel trpm4 is a positive regulator of pressure overload-induced cardiac hypertrophy', eLife, 10, http://dx.doi.org/10.7554/eLife.66582
, 2021, 'Cardiac Gq Receptors and Calcineurin Activation Are Not Required for the Hypertrophic Response to Mechanical Left Ventricular Pressure Overload', Frontiers in Cell and Developmental Biology, 9, http://dx.doi.org/10.3389/fcell.2021.639509
, 2021, 'In vitro cell stretching technology (IsoStretcher) as an approach to unravel Piezo1-mediated cardiac mechanotransduction', Progress in Biophysics and Molecular Biology, 159, pp. 22 - 33, http://dx.doi.org/10.1016/j.pbiomolbio.2020.07.003
, 2017, 'Endocardial TRPC-6 Channels Act as Atrial Mechanosensors and Load-Dependent Modulators of Endocardial/Myocardial Cross-Talk', JACC: Basic to Translational Science, 2, pp. 575 - 590, http://dx.doi.org/10.1016/j.jacbts.2017.05.006
, 2017, 'Standardized echocardiographic assessment of cardiac function in normal adult zebrafish and heart disease models', DMM Disease Models and Mechanisms, 10, pp. 63 - 76, http://dx.doi.org/10.1242/dmm.026989
, 2016, 'Development and Validation of a Novel Technique for High Frequency Echocardiography in Zebrafish Models of Health and Disease Provide Key Insights into Cardiac Physiology and Applications for Studying Heart Failure', Heart, Lung and Circulation, 25, pp. S106 - S106, http://dx.doi.org/10.1016/j.hlc.2016.06.251
, 2015, 'Irreversible triggers for hypertrophic cardiomyopathy are established in the early postnatal period', Journal of the American College of Cardiology, 65, pp. 560 - 569, http://dx.doi.org/10.1016/j.jacc.2014.10.069
, 2014, 'RhoA/ROCK signaling and pleiotropic α
, 2013, 'Studies of a Mouse Model of Cardiac α1A-Adrenergic Receptor Overexpression Provide Evidence For a Critical Role of RhoA/ROCK Signalling in Cardiac Contractility', Heart, Lung and Circulation, 22, pp. S59 - S59, http://dx.doi.org/10.1016/j.hlc.2013.05.143
, 2011, 'Nesprin-1 and actin contribute to nuclear and cytoskeletal defects in lamin A/C-deficient cardiomyopathy', Journal of Molecular and Cellular Cardiology, 50, pp. 479 - 486, http://dx.doi.org/10.1016/j.yjmcc.2010.12.001
, 2011, 'Regulation of murine cardiac contractility by activation of alpha(1A)-adrenergic receptor-operated Ca(2+) entry', Cardiovascular Research, 91, pp. 310 - 319
, 2007, 'Lentivirus vector-mediated gene transfer to the developing bronchiolar airway epithelium in the fetal lamb', Journal of Gene Medicine, 9, pp. 429 - 439
, 2003, 'Effects of fetal behavioral states on renal sympathetic nerve activity and arterial pressure of unanesthetized fetal sheep', American Journal of Physiology - Regulatory Integrative and Comparative Physiology, 285, http://dx.doi.org/10.1152/ajpregu.00252.2003
, 2002, 'Effects of Birth of Barorecptor-Mediated Changes in Heart Rate Variability in Lambs and Fetal Sheep', Clinical and Experimental Pharmacology and Physiology, 29, pp. 455 - 463
, 2002, 'The cardiovascular and renal effects of acute and chronic inhibition of nitric oxide production in fetal sheep', Experimental Physiology, 87, pp. 343 - 351
, 2001, 'The Selfish Brain and the Barker Hypothesis', Clinical and Experimental Pharmacology and Physiology, pp. 942 - 947
, 2000, 'Dielectric polarization process in Bi:SrTiO3', Journal of Physics and Chemistry of Solids, pp. 191 - 196
, 2000, 'Effect of cold on fetal heart rate and its variability', Clinical and Experimental Pharmacology and Physiology, pp. 607 - 611
, 2000, 'Measurement of baroreceptor mediated effects on heart rate variability in fetal sheep', Pediatric Research, pp. 233 - 239
, 1999, 'A method for determining baroreflex mediated sympathetic and parasympathetic control of the heart in pregnant and non-pregnant sheep', The Journal of Physiology, pp. 555 - 566
, 1999, 'Altered cardiovascular haemodynamics and baroreceptor-heart rate reflex in adult sheep after prenatal exposure to dexamethasone', Clinical Science, pp. 103 - 109
, 1999, 'Dielectric and ultrasonic anomalies at 16, 37, and 65K in SrTiO3', Physical Review - Section B - Condensed Matter, pp. 6661 - 6664
, 1998, 'Effects of hypoxaemia on foetal heart rate, variability and cardiac rhythm', Clinical and Experimental Pharmacology and Physiology, pp. 577 - 584
Conference Papers
, 2007, 'Cardiac restricted alpha 1A-Adrenergic receptor overexpression in the adult rodent heart induces a hypersensitive contractile response to adrenergic stimulation with reduced baseline contractility but no hypertrophy', in Circulation, Lippincott Williams & Wilkins, Philadelphia, PA, USA, pp. 195 - 195, presented at
, 2000, 'Effects of nitric oxide synthase inhibition on cardiovascular and renal function of fetal sheep', in Proceedings of the High Blood Pressure Research Council of Australia, University of Sydney, pp. 63, presented at
, 2000, 'Relationships between resting heart rate, baroreflex gain and the time to onset of heart rate and blood pressure responses to the valsalva maneuvre', in Proceedings of the High Blood Pressure Research Council of Australia, University of Sydney, pp. 29, presented at
, 2000, 'Effects of fetal hypertension and hypotension on fetal behavioural states and on renal sympathetic nerve activity', in Endocrincology and Development (Wyeth Meeting), McLaren Vale, SA, presented at
, 2000, 'Long-term nitric oxide synthase inhibition enhances the pressor responses to angiotensin II and noradrenaline in the fetal sheep', in Federation of American Societies for Experimantal Biology Journal, Federation American Society Exp Biol, Bethesda, MD, USA, pp. 17, presented at
, 2000, 'Effects of birth on baroreceptor mediated changes in heart rate variability in chronically catheterised fetal sheep', in Chinese Perinatal Society Annual Meeting, Harbin, China, presented at
, 2000, 'A method of determining baroreflex-mediated sympathetic and parasympathetic control of heart in pregnant and non-pregnant ewes', in Proceedings of Aust Neuroscience Society, Melbourne Convention Centre, pp. 180, presented at
, 2000, 'Effects of arterial pressure on renal sympathetic nerve activity of conscious unanaesthetised fetal sheep', in Proceedings of Aust Neuroscience Society, Melbourne Convention Centre, pp. 88, presented at
, 1999, 'Impact of long-term NOS inhibition on pressor responses in the fetal sheep', in Proceedings for the Australian Society for Medical Research, Leura, NSW, pp. 4-3, presented at
, 1999, 'Does nitric oxide deficiency in late gestation alter programming of the cardiovascular system?', in Perinatal Society of Aust and New Zealand, Melbourne, pp. 261, presented at
, 1999, 'The effect of netric oxide deficiency on the pressor reponses to angiotensin II and noradrenaline in fetal sheep?', in 13th Nat. Workshop on Fetal and Neonatal Physiol, Melbourne, pp. A38, presented at
, 1998, 'A new method of measuring baroreflex mediated sympathetic and parasympathetic regulation of the heart rates of adult and fetal sheep', in 4th Congress of the Federation of Asian and Oceanian Physiological Societies, Brisbane, Qld, presented at
, 1998, 'Programming of hypertension in sheep by short exposure to dexamethasone early in gestation', in 4th Congress of the Federation of Asian and Oceanian Physiological Societies, Brisbane, Qld, presented at
, 1998, 'A comparison of baroreceptor mediated effects on heart rate and on heart, rate variability in fetal, lamb and adult sheep', in Cardiovascular function in Health and Disease, Sydney, presented at
, 1998, 'A method of determining baroreflex mediated sympathetic and parasympathetic control of the heart in pregnant and non-pregnant sheep.', in Cardiovascular function in Health and Disease, Sydney, presented at
, 1998, 'A new method of measuring baroreflex mediated sympathetic and parasympathetic regulation of the heart rates of adult and fetal sheep', in Australian Physiol. Pharmacol Society, pp. 338, presented at
, 1998, 'Programming of hypertension in sheep by short exposure to dexamethasone early in gestation', in Australian Physiol. Pharmacol Society, pp. 346, presented at
, 1997, 'Comparison of the effect of change in arterial pressure on heart rate variability in fetal sheep, non-pregnant and pregnant ewes.', in FASEB Summer Research Conference, Perinatal Regulation of the Cardiovascular System, Colorado, USA, presented at
, 1997, 'Developmental changes in angiotensinogen gene expression and its protein content in fetal sheep.', in FASEB Summer Research Conference, Perinatal Regulation of the Cardiovascular System, Colorado, USA, presented at
, 1997, 'Assessment of the neural components of baroreflex mediated control of the heart using heart rate variability in the chronically catheterised pregnant sheep.', in 33rd International Union Physiological society, St Petersberg, presented at
, 1997, 'The fetal heart rate response to changes in arterial pressure.', in Hagan R (ed.), 1st Annual Congress of the Perinatal Society of Australia and New Zealand, Fremantle, WA, presented at