My Expertise
Glycomics, Mass Spectrometry, Proteoglycans, Tissue Regeneration, mast cell biology, Biochemistry, Biomedical Engineering, Cell Biology and Gene Regulation, Cardiology and Vascular Disease, Proteomics
Fields of Research (FoR)
Biochemistry and Cell Biology, Biomedical EngineeringBiography
Research Interests:
Tissue repair and regeneration involves interactions between the extracellular environment that binds growth signals and guides cell and tissue behavior. The activity of these signals is controlled by glycosylated molecules known as proteoglycans and this is my central area of research interest.
Broad Research Areas:
Biochemistry, Biomedical Engineering, Cell Biology and Gene Regulation, Cardiology and Vascular Disease,...view more
Research Interests:
Tissue repair and regeneration involves interactions between the extracellular environment that binds growth signals and guides cell and tissue behavior. The activity of these signals is controlled by glycosylated molecules known as proteoglycans and this is my central area of research interest.
Broad Research Areas:
Biochemistry, Biomedical Engineering, Cell Biology and Gene Regulation, Cardiology and Vascular Disease, Proteomics
Society Memberships & Professional Activities:
International Society for Matrix Biology, American Society for Matrix Biology, Australian and New Zealand Society for Matrix Biology - President, Australian Society for Medical Research
Specific Research Keywords:
Glycomics, Mass Spectrometry, Proteoglycans, Tissue Regeneration, mast cell biology
Location
Level 5, Samuels Bldg
University of New South Wales
Sydney, Australia, 2052
Map reference (Google map)
Contact
Publications
ORCID as entered in ROS
https://orcid.org/0000-0003-1835-802X
Research Activities
This project investigates the structures of heparan sulphate proteoglycans that control the tissue development and aging including liver, heart, kidney, palate and brain by studying genetically modified mice. Proteoglycans bind to the growth signaling molecules via their charged sugar chains but little is known about the relative importance of the different proteoglycans in these tissues and how the different sugar structures change during regeneration. This proposal will provide a significant shift in our fundamental understanding of the knowledge of the mechanisms involved in…
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