By Emeritus Professor Rodney Phillips

Journal articles

Oxenius A; Price DA; Easterbrook PJ; O'Callaghan CA; Kelleher AD; Whelan JA; Sontag G; Sewell AK; Phillips RE, 2000, 'Early highly active antiretroviral therapy for acute HIV-1 infection preserves immune function of CD8⁺ and CD4⁺ T lymphocytes', Proceedings of the National Academy of Sciences of the United States of America, 97, pp. 3382 - 3387, http://dx.doi.org/10.1073/pnas.97.7.3382

Sewell AK; Price DA; Oxenius A; Kelleher AD; Phillips RE, 2000, 'Cytotoxic T lymphocyte responses to human immunodeficiency virus: Control and escape', Stem Cells, 18, pp. 230 - 244, http://dx.doi.org/10.1634/stemcells.18-4-230

Gileadi U; Moins-Teisserenc HT; Correa I; Booth BL; Dunbar PR; Sewell AK; Trowsdale J; Phillips RE; Cerundolo V, 1999, 'Generation of an immunodominant CTL epitope is affected by proteasome subunit composition and stability of the antigenic protein', Journal of Immunology, 163, pp. 6045 - 6052

Whelan JA; Dunbar PR; Price DA; Purbhoo MA; Lechner F; Ogg GS; Griffiths G; Phillips RE; Cerundolo V; Sewell AK, 1999, 'Specificity of CTL interactions with peptide-MHC class I tetrameric complexes is temperature dependent', Journal of Immunology, 163, pp. 4342 - 4348

Sewell AK; Price DA; Teisserenc H; Booth BL; Gileadi U; Flavin FM; Trowsdale J; Phillips RE; Cerundolo V, 1999, 'IFN-γ exposes a cryptic cytotoxic T lymphocyte epitope in HIV-1 reverse transcriptase', Journal of Immunology, 162, pp. 7075 - 7079

Price DA; Klenerman P; Booth BL; Phillips RE; Sewell AK, 1999, 'Cytotoxic T lymphocytes, chemokines and antiviral immunity', Immunology Today, 20, pp. 212 - 216, http://dx.doi.org/10.1016/S0167-5699(99)01447-4

Sewell AK; Gerth UC; Price DA; Purbhoo MA; Boulter JM; Gao GF; Bell JI; Phillips RE; Jakobsen BK, 1999, 'Antagonism of cytotoxic T-lymphocyte activation by soluble CD8', Nature Medicine, 5, pp. 399 - 404, http://dx.doi.org/10.1038/7398

Price DA; O'Callaghan CA; Whelan JA; Easterbrook PJ; Phillips RE, 1999, 'Cytotoxic T lymphocytes and viral evolution in primary HIV-1 infection', Clinical Science, 97, pp. 707 - 718, http://dx.doi.org/10.1042/cs0970707

Harcourt GC; Garrard S; Davenport MP; Edwards A; Phillips RE, 1998, 'HIV-1 variation diminishes CD4 T lymphocyte recognition', Journal of Experimental Medicine, 188, pp. 1785 - 1793, http://dx.doi.org/10.1084/jem.188.10.1785

Price DA; Meier UC; Klenerman P; Purbhoo MA; Phillips RE; Sewell AK, 1998, 'The influence of antigenic variation an cytotoxic T lymphocyte responses in HIV-1 infection', Journal of Molecular Medicine, 76, pp. 699 - 708, http://dx.doi.org/10.1007/s001090050270

Price DA; Price DA; O'callaghan CA; Whelan JA; Altes HK; Easterbrook PJ; Troop M; Jakobsen BK; Bonhoeffer S; Nowak MA; Bell JI; Phillips RE, 1998, 'Longitudinal Analysis of Cytotoxic T Lymphocyte Responses and Viral Antigenic Diversification during Primary Hiv-1 Infection', Clinical Science, 95, pp. 12P - 12P, http://dx.doi.org/10.1042/cs095012pa

Purbhoo MA; Sewell AK; Klenerman P; Goulder PJR; Hilyard KL; Bell JI; Jakobsen BK; Phillips RE, 1998, 'Copresentation of natural HIV-1 agonist and antagonist ligands fails to induce the T cell receptor signaling cascade', Proceedings of the National Academy of Sciences of the United States of America, 95, pp. 4527 - 4532, http://dx.doi.org/10.1073/pnas.95.8.4527

Price DA; Sewell AK; Dong T; Tan R; Goulder PJR; Rowland-Jones SL; Phillips RE, 1998, 'Antigen-specific release of β-chemokines by anti-HIV-1 cytotoxic T lymphocytes', Current Biology, 8, pp. 355 - 358, http://dx.doi.org/10.1016/s0960-9822(98)70138-1

Bangham CRM; Phillips RE, 1997, 'What is required of an HIV vaccine?', Lancet, 350, pp. 1617 - 1621, http://dx.doi.org/10.1016/S0140-6736(97)03258-3

Sewell AK; Harcourt GC; Goulder PJR; Price DA; Phillips RE, 1997, 'Antagonism of cytotoxic T lymphocyte-mediated lysis by natural HIV-1 altered peptide ligands requires simultaneous presentation of agonist and antagonist peptides', European Journal of Immunology, 27, pp. 2323 - 2329, http://dx.doi.org/10.1002/eji.1830270929

Price DA; Goulder PJR; Klenerman P; Sewell AK; Easterbrook PJ; Troop M; Bangham CRM; Phillips RE, 1997, 'Cytotoxic T-Lymphocyte Activity Selects Immune Escape Variants during Primary HIV-1 Infection', Clinical Science, 93, pp. 20P - 20P, http://dx.doi.org/10.1042/cs093020pa

Goulder PJR; Edwards A; Phillips RE; McMichael AJ, 1997, 'Identification of a novel HLA-B*3501-restricted cytotoxic T lymphocyte epitope using overlapping peptides [3]', AIDS, 11, pp. 930 - 932

Goulder PJR; Reid SW; Price DA; O'Callaghan CA; McMichael AJ; Phillips RE; Jones EY, 1997, 'Combined structural and immunological refinement of HIV-1 HLA-B8-restricted cytotoxic T lymphocyte epitopes', European Journal of Immunology, 27, pp. 1515 - 1521, http://dx.doi.org/10.1002/eji.1830270630

McMichael AJ; Phillips RE, 1997, 'Escape of human immunodeficiency virus from immune control', Annual Review of Immunology, 15, pp. 271 - 296, http://dx.doi.org/10.1146/annurev.immunol.15.1.271

Goulder PJR; Sewell AK; Lalloo DG; Price DA; Whelan JA; Evans J; Taylor GP; Luzzi G; Giangrande P; Phillips RE; McMichael AJ, 1997, 'Patterns of immunodominance in HIV-1-specific cytotoxic T lymphocyte responses in two human histocompatibility leukocyte antigens (HLA)-identical siblings with HLA-A*0201 are influenced by epitope mutation', Journal of Experimental Medicine, 185, pp. 1423 - 1433, http://dx.doi.org/10.1084/jem.185.8.1423

Goulder PJR; Edwards A; Phillips RE; McMichael AJ, 1997, 'Identification of a novel HLA-B*2705-restricted cytotoxic T-lymphocyte epitope within a conserved region of HIV-1 nef [3]', AIDS, 11, pp. 536 - 538

Price DA; Goulder PJR; Klenerman P; Sewell AK; Easterbrook PJ; Troop M; Bangham CRM; Phillips RE, 1997, 'Positive selection of HIV-1 cytotoxic T lymphocyte escape variants during primary infection', Proceedings of the National Academy of Sciences of the United States of America, 94, pp. 1890 - 1895, http://dx.doi.org/10.1073/pnas.94.5.1890

Goulder PJR; Phillips RE; Colbert RA; McAdam S; Ogg G; Nowak MA; Giangrande P; Luzzi G; Morgan B; Edwards A; Mcmichael AJ; Rowland-Jones S, 1997, 'Late escape from an immunodominant cytotoxic T-lymphocyte response associated with progression to AIDS', Nature Medicine, 3, pp. 212 - 217, http://dx.doi.org/10.1038/nm0297-212

Goulder P; Price D; Nowak M; Rowland-Jones S; Phillips R; McMichael A, 1997, 'Co-evolution of human immunodeficiency virus and cytotoxic T-lymphocyte responses', Immunological Reviews, 159, pp. 17 - 29, http://dx.doi.org/10.1111/j.1600-065X.1997.tb01004.x

Ronan A; Azad AK; Rahman O; Phillips RE; Bennish ML, 1997, 'Hyperglycemia during childhood diarrhea', Journal of Pediatrics, 130, pp. 45 - 51, http://dx.doi.org/10.1016/S0022-3476(97)70309-3

Goulder PJR; Edwards A; Phillips RE; McMichael AJ, 1997, 'Identification of a novel HLA-A24-restricted cytotoxic T-lymphocyte epitope within HIV-1 Nef [1]', AIDS, 11, pp. 1883 - 1884, http://dx.doi.org/10.1097/00002030-199715000-00015

Goulder PJR; Bunce M; Luzzi G; Phillips RE; McMichael AJ, 1997, 'Potential underestimation of HLA-C-restricted cytotoxic T-lymphocyte responses [2]', AIDS, 11, pp. 1884 - 1886, http://dx.doi.org/10.1097/00002030-199715000-00016

Goulder PJR; Phillips RE; Colbert RA; McAdam S; Ogg G; Giangrande P; Luzzi G; Morgan B; Edwards A; McMichael A; Rowland-Jones S, 1997, 'Late escape from an immunodominant cytotoxic T lymphocyte response associated with progression to AIDS', Immunology Letters, 56, pp. 25 - 25, http://dx.doi.org/10.1016/s0165-2478(97)85097-3

Price DA; Goulder PJR; Klenerman P; Sewell AK; Easterbrook PJ; Troop M; Bangham CRM; Phillips RE, 1997, 'Positive selection mediated by cytotoxic T lymphocytes influences HIV-1 evolution during primary infection', Immunology Letters, 56, pp. 438 - 438, http://dx.doi.org/10.1016/s0165-2478(97)86778-8

Klenerman P; Phillips RE; Rinaldo CR; Wahl LM; Ogg G; May RM; Mcmichael AJ; Nowak MA, 1996, 'Cytotoxic T lymphocytes and viral turnover in HIV type 1 infection', Proceedings of the National Academy of Sciences of the United States of America, 93, pp. 15323 - 15328, http://dx.doi.org/10.1073/pnas.93.26.15323

Klenerman P; Phillips R; McMichael A, 1996, 'Cytotoxic T-cell antagonism in HIV-1', Seminars in Virology, 7, pp. 31 - 39, http://dx.doi.org/10.1006/smvy.1996.0005

Klenerman P; Luzzi G; McIntyre K; Phillips R; McMichael A, 1996, 'Identification of a novel HLA-A25-restricted epitope in a conserved region of p24 gag (positions 71-80) [9]', AIDS, 10, pp. 348 - 350, http://dx.doi.org/10.1097/00002030-199603000-00023

Goulder PJR; Bunce M; Krausa P; McIntyre K; Crowley S; Morgan B; Edwards A; Giangrande P; Phillips RE; McMichael AJ, 1996, 'Novel, cross-restricted, conserved, and immunodominant cytotoxic T lymphocyte epitopes in slow progressors in HIV type 1 infection', AIDS Research and Human Retroviruses, 12, pp. 1691 - 1698, http://dx.doi.org/10.1089/aid.1996.12.1691

Meier UC; Klenerman P; Griffin P; James W; Köppe B; Larder B; McMichael A; Phillips R, 1995, 'Cytotoxic T lymphocyte lysis inhibited by viable HIV mutants', Science, 270, pp. 1360 - 1362

Lalloo D; Klenerman P; McAdam S; Köppe B; Rowland-Jones S; Phillips R; McMichael A, 1995, 'Immune Escape in Hiv Infection', Clinical Science, 88, pp. 31P - 31P, http://dx.doi.org/10.1042/cs088031p

Nowak MA; May RM; Phillips RE; Rowland-Jones S; Lalloo DG; McAdam S; Klenerman P; Köppe B; Sigmund K; Bangham CRM; McMichael AJ, 1995, 'Antigenic oscillations and shifting immunodominance in HIV-1 infections', Nature, 375, pp. 606 - 611, http://dx.doi.org/10.1038/375606a0

McAdam S; Klenerman P; Tussey L; Rowland-Jones S; Lalloo D; Phillips R; Edwards A; Giangrande P; Brown AL; Gotch F; McMichael A, 1995, 'Immunogenic HIV variant peptides that bind to HLA-B8 can fail to stimulate cytotoxic T lymphocyte responses', Journal of Immunology, 155, pp. 2729 - 2736

Klenerman P; Meier U; Phillips RE; McMichael AJ, 1995, 'The effects of natural altered peptide ligands on the whole blood cytotoxic T lymphocyte response to human immunodeficiency virus', European Journal of Immunology, 25, pp. 1927 - 1931, http://dx.doi.org/10.1002/eji.1830250720

Solomon T; Phillips RE; Felix JM; Samuel M; Dengo GA; Schapira A; Saldanha RA, 1994, 'Hypoglycaemia in paediatric admissions in Mozambique', The Lancet, 343, pp. 149 - 150, http://dx.doi.org/10.1016/S0140-6736(94)90937-7

Klenerman P; Rowland-Jones S; McAdam S; Edwards J; Daenke S; Lalloo D; Köppe B; Rosenberg W; Boyd D; Edwards A; Giangrande P; Phillips RE; McMichael AJ, 1994, 'Cytotoxic T-cell activity antagonized by naturally occurring HIV-1 Gag variants', Nature, 369, pp. 403 - 407, http://dx.doi.org/10.1038/369403a0

Conlon CP; Klenerman P; Edwards A; Larder BA; Phillips RE, 1994, 'Heterosexual transmission of human immunodeficiency virus type 1 variants associated with zidovudine resistance', Journal of Infectious Diseases, 169, pp. 411 - 415, http://dx.doi.org/10.1093/infdis/169.2.411

Phillips RE; McMichael AJ, 1993, 'How does the HIV escape cytotoxic T cell immunity?', Chemical Immunology, 56, pp. 150 - 164, http://dx.doi.org/10.1159/000319162

Phillips RE; Hatz C; Warrell DA; Looareesuwan S; Molyneux ME, 1993, 'Hypoglycaemia and counterregulatory hormone responses in severe falciparum malaria: Treatment with Sandostatin', QJM, 86, pp. 233 - 240, http://dx.doi.org/10.1093/oxfordjournals.qjmed.a068802

Tin-Nu-Swe ; Myint-Lwin ; Tin-Tun ; Thein-Than ; Tun-Pe ; Robertson JIS; Leckie BJ; Phillips RE; Warrell DA, 1993, 'Renal ischaemia, transient glomerular leak and acute renal tubular damage in patients envenomed by russell’s vipers (daboia russelii siamensis) in myanmar', Transactions of the Royal Society of Tropical Medicine and Hygiene, 87, pp. 678 - 681, http://dx.doi.org/10.1016/0035-9203(93)90290-7

Phillips RE; Pasvol G, 1992, 'Anaemia of Plasmodium falciparum malaria', Bailliere's Clinical Haematology, 5, pp. 315 - 330, http://dx.doi.org/10.1016/S0950-3536(11)80022-3

Rowland-Jones SL; Phillips RE; Nixon DF; Gotch FM; Edwards JP; Ogunlesi AO; Elvin JG; Rothbard JA; Bangham CRM; Rizza CR; Mcmichael AJ, 1992, 'Human Immunodeficiency Virus Variants That Escape Cytotoxic T-Cell Recognition', AIDS Research and Human Retroviruses, 8, pp. 1353 - 1354, http://dx.doi.org/10.1089/aid.1992.8.1353

Thein-Than ; Tin-Tun ; Hla-Pe ; Phillips RE; Myint-Lwin ; Tin-Nu-Swe ; Warrell DA, 1991, 'Development of renal function abnormalities following bites by Russell's vipers (Daboia russelii siamensis) in Myanmar', Transactions of the Royal Society of Tropical Medicine and Hygiene, 85, pp. 404 - 409, http://dx.doi.org/10.1016/0035-9203(91)90307-K

Phillips RE; Rowland-Jones S; Nixon DF; Gotch FM; Edwards JP; Ogunlesi AO; Elvin JG; Rothbard JA; Bangham CRM; Rizza CR; McMichael AJ, 1991, 'Human immunodeficiency virus genetic variation that can escape cytotoxic T cell recognition', Nature, 354, pp. 453 - 459, http://dx.doi.org/10.1038/354453a0

Warrell DA; Phillips RE; Garrard CS, 1991, 'Intensive care unit management of severe malaria', Clinical Intensive Care, 2, pp. 86 - 96

Phillips RE; Solomon T, 1990, 'Cerebral malaria in children', The Lancet, 336, pp. 1355 - 1360, http://dx.doi.org/10.1016/0140-6736(90)92903-U

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