Select Publications
Journal articles
2021, 'A survey of Australian public attitudes towards funding of high cost cancer medicines', Health Policy, 125, pp. 327 - 334, http://dx.doi.org/10.1016/j.healthpol.2020.12.002
,2014, 'Kinetics of drug interaction with the K
2013, 'Influence of cardiovascular absolute risk assessment on prescribing of antihypertensive and lipid-lowering medications: A cluster randomized controlled trial', American Heart Journal, 167, pp. 28 - 35, http://dx.doi.org/10.1016/j.ahj.2013.10.002
,2011, 'Interdisciplinary, cross-institutional collaborations: the Academic Health Sciences Centre as a key to addressing complex health problems and advancing research-based health care', Collegian, 18, pp. 1 - 2, http://dx.doi.org/10.1016/j.colegn.2011.01.003
,2010, 'Cardiovascular absolute risk assessment and management: Engagement and outcomes in general practice patients', Australian Family Physician, 39, pp. 954 - 958
,2010, 'Experience in implementation of cardiovascular absolute risk assessment and management in Australian general practice.', International Journal of Clinical Practice, 64, pp. 1166 - 1167, http://www3.interscience.wiley.com/cgi-bin/fulltext/123529467/HTMLSTART
,2010, 'Prerequisites for implementing a cardiovascular absolute risk assessment in general practice: a qualitative study of Australian general practitioners' and patients' views', Journal of Evaluation in Clinical Practice, 16, pp. 580 - 584, http://www3.interscience.wiley.com/cgi-bin/fulltext/123396718/PDFSTART
,2010, 'Variability in response to clopidogrel', Australian Prescriber, 33, pp. 62 - 63
,2009, 'Insight into Accurate Testing of Drugs which Cause the Acquired Long-QT Syndrome', Heart, Lung and Circulation, 18, pp. S135 - S135, http://dx.doi.org/10.1016/j.hlc.2009.05.306
,2009, 'Not all hERG pore domain mutations have a severe phenotype: G584S has an inactivation gating defect with mild phenotype compared to G572S, which has a dominant negative trafficking defect and a severe phenotype', Journal of Cardiovascular Electrophysiology, 20, pp. 923 - 930, http://dx.doi.org/10.1111/j.1540-8167.2009.01468.x
,2009, 'Study protocol for a randomized controlled trial: The feasibility and impact of cardiovascular absolute risk assessment in Australian general practice', American Heart Journal, 157, pp. 436 - 441, http://dx.doi.org/10.1016/j.ahj.2008.11.016
,2008, 'Drug Binding to the Inactivated State Is Necessary but Not Sufficient for High-Affinity Binding to Human Ether-a-go-go-Related Gene Channels', Molecular Pharmacology, 74, pp. 1443 - 1452
,2007, 'Mechanism of block of the hERG K+ channel by the scorpion toxin CnErg1', Biophysical Journal, 92, pp. 3915 - 3929
,2007, 'The S631A mutation causes a mechanistic switch in the block of hERG channels by CnErgl', Biophysical Journal, 93, pp. 32 - 34
,2006, 'Effect of S5P alpha-helix charge mutants on inactivation of hERG K+ channels', The Journal of Physiology, 573, pp. 291 - 304
,2006, 'Greater CD4 T-cell gains after one year of antiretroviral therapy are associated with lower HIV-1 pol replication capacity.', AIDS, 20, pp. 2123 - 2125
,2006, 'Off label use of medicines: consensus recommendations for evaluating appropriateness', Medical Journal of Australia, 185, pp. 544 - 548
,2005, 'Amiodarone', Australian Prescriber, 28, pp. 150 - 154
,2005, 'Ion channelopathies: What have they taught us about arrhythmias and anti-arrhythmic therapy', Clinical and Experimental Pharmacology and Physiology, 32, pp. 595 - 595
,2005, 'Tryptophan scanning mutagenesis of the HERG K+ channel: the S4 domain is loosely packed and likely to be lipid exposed', The Journal of Physiology, 569, pp. 367 - 379
,2004, 'Erratum: The HERG K+ channel: Progress in understanding the molecular basis of its unusual gating kinetics (European Biophysics Journal (2004) 33 (89-97))', European Biophysics Journal, 33, pp. 468
,2004, 'The HERG K+ channel: progress in understanding the molecular basis of its unusual gating kinetics (vol 33, pg 89, 2004)', EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 33, pp. 468 - 468, http://dx.doi.org/10.1007/s00249-004-0419-y
,2004, 'The HERG K+ channel: Progress in understanding the molecular basis of its unusual gating kinetics', European Biophysics Journal, 33, pp. 89 - 97, http://dx.doi.org/10.1007/s00249-003-0338-3
,2004, 'Effect of pravastatin compared with placebo initiated within 24 hours of onset of acute myocardial infarction or unstable angina: The Pravastatin in Acute Coronary Treatment (PACT) trial', American Heart Journal, 148
,2004, 'Guidelines for off-label use of medicines', Clinical and Experimental Pharmacology and Physiology, 31, pp. A226 - A226
,2004, 'Inherited cardiac arrhythmia syndromes: What have they taught us aboutarrhythmias and anti-arrhythmic therapy?', Clinical and Experimental Pharmacology and Physiology, 31, pp. 906 - 912
,2004, 'Left atrial hematoma complicating inferior myocardial infarction', Journal of the American Society of Echocardiography, 17, pp. 1201 - 1203
,2004, 'Molecular basis of slow activation of the human ether-a-go-go relatedgene potassium channel', The Journal of Physiology, 558, pp. 417 - 431
,2004, 'The HERGK+ channel: Progress in understanding the molecular basis of its unusual gating kinetics.', European Biophysics Journal With Biophysics Letters, 33, pp. 80 - 97
,2004, 'The intracellular chloride ion channel protein CLIC1 undergoes a redox-controlled structural transition', The Journal of Biological Chemistry, 279, pp. 9298 - 9305
,2003, 'Digoxin in heart failure', Medical Journal of Australia, 179, pp. 98 - 102
,2003, 'Extracellular acidosis modulates drug block of Kv4.3 currents by flecainide and quinidine', Journal of Cardiovascular Electrophysiology, 14, pp. 641 - 650
,2003, 'Structure of the HERGK+ channel S5P extracellulal linker: Role of an amphipathic a-helix in C-type inactivation.', Journal of Biochemistry, 278, pp. 42136 - 42148
,2002, 'Global cardiology and come to Australia: 14th world congress of cardiology, Sydney, 5-9 May 2002', Medical Journal of Australia, 177, pp. 473 - 475, http://dx.doi.org/10.5694/j.1326-5377.2002.tb04913.x
,2002, 'Erratum: A potassium ion channel is involved in cytokine production by activated human macrophages (Clinical and Experimental Immunology (2002) 130 (67-74))', Clinical and Experimental Immunology, 130, pp. 559 - 561, http://dx.doi.org/10.1046/j.1365-2249.2002.02041.x
,2002, 'A potassium ion channel is involved in cytokine production by activated human macrophages', Clinical and Experimental Immunology, 130, pp. 67 - 74
,2002, 'Effects of components of ischemia on the Kv4.3 current stably expressed in chinese hamster ovary cells', Journal of Mol Cell Caridiol, 34, pp. 197 - 207
,2002, 'Recombinant CLIC1 (NCC27) assembles in lipid bilayers via a pH-dependent two-state process to form chloride ion channels with identical characteristics to those observed in Chinese Hamster Ovary cells expressing CLIC1', The Journal of Biological Chemistry, 277, pp. 26003 - 26011
,2001, 'Clozapine and sudden death [10]', Journal of Clinical Psychopharmacology, 21, pp. 630 - 632, http://dx.doi.org/10.1097/00004714-200112000-00023
,2001, 'HERG K+ channels: Friend and foe', Trends in Pharmacological Sciences, 22, pp. 240 - 246, http://dx.doi.org/10.1016/S0165-6147(00)01662-X
,2001, 'Heart week 2001: "Get active"! A call to action', Medical Journal of Australia, 174, pp. 381 - 382, http://dx.doi.org/10.5694/j.1326-5377.2001.tb143337.x
,2001, 'Crystal structure of a soluble form of the Intracellular Chloride Ion Channel CLIC1 (NCC27) at 1.4-A resolution', The Journal of Biological Chemistry, pp. 44993 - 45000
,2001, 'Heart Week 2001: `Get active`! A call to action [editorial]', Medical Journal of Australia, 174, pp. 381 - 382
,2000, 'The nuclear chloride ion channel NCC27 is involved in regulation of the cell cycle', Journal of Physiology, 529, pp. 541 - 552, http://dx.doi.org/10.1111/j.1469-7793.2000.00541.x
,2000, 'Guidelines for unstable angina: Evidence-based medicine in the information age', Medical Journal of Australia, 173, pp. 399 - 400, http://dx.doi.org/10.5694/j.1326-5377.2000.tb139265.x
,2000, 'The heart of psychotropic drug therapy.', Lancet, 355, pp. 1824 - 1825, http://dx.doi.org/10.1016/S0140-6736(05)73082-8
,2000, 'Kinetics of onset of rate-dependent effects of Class I antiarrhythmic drugs are important in determining their effects on refractoriness in guinea-pig ventricle, and provide a theoretical basis for their subclassification', Cardiovascular Research, 45, pp. 55 - 56, http://dx.doi.org/10.1016/S0008-6363(99)00308-9
,2000, 'The heart of psychotropic drug therapy.', Lancet, 355, pp. 1825, http://dx.doi.org/10.1016/S0140-6736(05)73083-X
,2000, 'Update on the use of magnesium as an antiarrhythmic drug', Cardiac Electrophysiology Review, 4, pp. 251 - 254, http://dx.doi.org/10.1023/A:1026543431623
,2000, 'Comparative effects of azimilide and ambasilide on the human ether-a-go-go-related gene (HERG) potassium channel', Cardiovascular Research, pp. 44 - 58
,