Select Publications
Journal articles
, 2026, 'The Governance Gap: Democratizing Drug Development Through Decision Architecture', Clinical Pharmacology and Therapeutics, http://dx.doi.org/10.1002/cpt.70476
, 2025, 'Rethinking pharmaceutical development: A not-for-profit model to address global health inequities', Future Healthcare Journal, 12, pp. 100255, http://dx.doi.org/10.1016/j.fhj.2025.100255
, 2024, 'The use of quantitative clinical pharmacology approaches to support moxidectin dosing recommendations in lactation', Plos Neglected Tropical Diseases, 18, http://dx.doi.org/10.1371/journal.pntd.0012351
, 2022, 'Pharmacokinetics of oral moxidectin in individuals with Onchocerca volvulus infection', Plos Neglected Tropical Diseases, 16, http://dx.doi.org/10.1371/journal.pntd.0010005
, 2021, 'Drug repurposing: Misconceptions, challenges, and opportunities for academic researchers', Science Translational Medicine, 13, http://dx.doi.org/10.1126/scitranslmed.abd5524
, 2019, 'A framework for the development of effective anti-metastatic agents', Nature Reviews Clinical Oncology, 16, pp. 185 - 204, http://dx.doi.org/10.1038/s41571-018-0134-8
, 2018, 'Creative use of the priority review voucher by public and not-for-profit actors delivers the first new FDA-approved treatment for river blindness in 20 years', Plos Neglected Tropical Diseases, 12, http://dx.doi.org/10.1371/journal.pntd.0006837
, 2018, 'Evaluation of the Cardiac Safety of Long-Acting Endectocide Moxidectin in a Randomized Concentration-QT Study', Clinical and Translational Science, 11, pp. 582 - 589, http://dx.doi.org/10.1111/cts.12583
, 2016, 'Preliminary consultation on preferred product characteristics of benzathine penicillin G for secondary prophylaxis of rheumatic fever', Drug Delivery and Translational Research, 6, pp. 572 - 578, http://dx.doi.org/10.1007/s13346-016-0313-z
, 2013, 'Non-Immunogenicity of Overlapping Gag Peptides Pulsed on Autologous Cells after Vaccination of HIV Infected Individuals', Plos One, 8, http://dx.doi.org/10.1371/journal.pone.0074389
, 2013, 'A Randomised, Placebo-Controlled, First-In-Human Study of a Novel Clade C Therapeutic Peptide Vaccine Administered Ex Vivo to Autologous White Blood Cells in HIV Infected Individuals', Plos One, 8, http://dx.doi.org/10.1371/journal.pone.0073765
, 2012, 'A first-in-man, double blind, placebo controlled study of the candidate therapeutic vaccine Opal-HIV-Gag(c) in HIV infected patients receiving HAART', Retrovirology, 9, pp. o54, http://dx.doi.org/10.1186/1742-4690-9-s2-o54
, 2012, 'Immune response after vaccination of HIV infected individuals receiving HAART with overlapping gag peptides pulsed on autologous cells', Retrovirology, 9, pp. p115, http://dx.doi.org/10.1186/1742-4690-9-s2-p115
, 2011, 'A Phase I Study to Determine Safety, Tolerability and Bioactivity of Nexvax2® in HLA DQ2+ Volunteers With Celiac Disease Following a Long-Term, Strict Gluten-Free Diet', Gastroenterology, 140, pp. s-437-s-438, http://dx.doi.org/10.1016/s0016-5085(11)61794-0
, 2010, 'Dimethyl sulfoxide (DMSO) exposure to human peripheral blood mononuclear cells (PBMCs) abolish T cell responses only in high concentrations and following coincubation for more than two hours', Journal of Immunological Methods, 356, pp. 70 - 78, http://dx.doi.org/10.1016/j.jim.2010.01.014
, 2009, 'Moving candidate vaccines into development from research: Lessons from HIV', Immunology and Cell Biology, 87, pp. 366 - 370, http://dx.doi.org/10.1038/icb.2009.30
, 2006, 'Dose-response relationship of DNA and recombinant fowlpox virus prime-boost HIV vaccines.', Human Vaccines, 2, pp. 134 - 136
, 2005, 'Subtype AE HIV-1 DNA and recombinant Fowlpoxvirus vaccines encoding five shared HIV-1 genes: safety and T cell immunogenicity in macaques', Vaccine, 23, pp. 1949 - 1956, http://www.sciencedirect.com/science/article/B6TD4-4DS4075-2/2/4ac957fc8ef72984bea88998a0965b95
, 2004, 'The renal tolerance of low-dose adefovir dipivoxil by lamivudine-resistant individuals co-infected with hepatitis B and HIV', Nephrology Dialysis Transplantation, 19, pp. 386 - 390, http://dx.doi.org/10.1093/ndt/gfg505
, 2004, 'Adefovir Dipivoxil Alone or in Combination with Lamivudine in Patients with Lamivudine-Resistant Chronic Hepatitis B', Gastroenterology, 126, pp. 91 - 101, http://dx.doi.org/10.1053/j.gastro.2003.10.051
, 2003, 'Adefovir dipivoxil 10 mg (ADV) results in consistent efficacy in chronic hepatitis B (CHB) patients with diverse baseline characteristics', Journal of Hepatology, 38, pp. 153 - 154, http://dx.doi.org/10.1016/s0168-8278(03)80795-x
, 2003, 'Changes in alanine aminotransferase (ALT) and YMDD mutation profile associated with switching from lamivudine (LAM) to either adefovir dipivoxil (ADV) or combination LAM plus ADV in chronic hepatitis B (CHB) patients with LAM resistance', Gastroenterology, 124, pp. A715 - A715, http://dx.doi.org/10.1016/s0016-5085(03)83608-9
, 2003, 'Resistance profile of adefovir dipivoxil (ADV) in immunocompetent and immunocompromised chronic hepatitis B patients after 48 weeks of adefovir dipivoxil therapy', Journal of Hepatology, 38, pp. 182 - 182, http://dx.doi.org/10.1016/s0168-8278(03)80004-1
, 2002, 'Adefovir dipivoxil (ADV) alone and in combination with lamivudine (LAM) suppresses LAM-resistant hepatitis B virus (HBV) replication: 16 week interim analysis', Journal of Hepatology, 36, pp. 6 - 7, http://dx.doi.org/10.1016/s0168-8278(02)80013-7
, 2002, 'Loss of lamivudine resistance mutations after patients switched to adefovir dipivoxil therapy', Journal of Hepatology, 36, pp. 7 - 7, http://dx.doi.org/10.1016/s0168-8278(02)80015-0
, 2002, 'Safety and efficacy of long-term adefovir dipivoxil (ADV) for lamivudine-resistant (LAM-R) HBV in HIV infected patients', Journal of Hepatology, 36, pp. 138 - 138, http://dx.doi.org/10.1016/s0168-8278(02)80496-2
, 2002, 'Tenofovir disoproxil fumarate (TDF) suppresses lamivudine-resistant HBV replication in patients co-infected with HIV/HBV', Journal of Hepatology, 36, pp. 138 - 138, http://dx.doi.org/10.1016/s0168-8278(02)80495-0