By Professor Arun Vishwanathan Krishnan

Journal articles

Singh I; Issar T; Poynten AM; Milner K-L; Krishnan AV; Dhanapalaratnam R, 2024, 'Evaluation of the Impact of Advanced Glycation End-Products on Peripheral Neuropathy Outcomes in Type 2 Diabetes', Biomedicines, 12, pp. 2518 - 2518, http://dx.doi.org/10.3390/biomedicines12112518

Dhanapalaratnam R; Issar T; Wang LL; Tran D; Poynten AM; Milner KL; Kwai NCG; Krishnan AV, 2024, 'Effect of Metformin on Peripheral Nerve Morphology in Type 2 Diabetes: A Cross-Sectional Observational Study', Diabetes, 73, pp. 1875 - 1882, http://dx.doi.org/10.2337/db24-0365

Tummanapalli SS; Wang LL; Dhanapalaratnam R; Poynten A; Papas EB; Krishnan AV; Markoulli M, 2024, 'Moderate-severe peripheral neuropathy in diabetes associated with an increased risk of dry eye disease', Optometry and Vision Science, 101, pp. 563 - 570, http://dx.doi.org/10.1097/OPX.0000000000002178

Hoang P; Sturnieks DL; Butler A; Chaplin C; Hicks C; Lo J; Ratanapongleka M; Robinson S; Smith N; Turner J; Krishnan AV; Barnett M; Gandevia S; Lord SR; Menant JC, 2024, 'A custom-built step exergame training programme to prevent falls in people with multiple sclerosis: A multicentre randomised controlled trial', Multiple Sclerosis Journal, 30, pp. 571 - 584, http://dx.doi.org/10.1177/13524585241229360

Dhanapalaratnam R; Issar T; Poynten AM; Milner KL; Kwai NCG; Krishnan AV, 2024, 'Progression of axonal excitability abnormalities with increasing clinical severity of diabetic peripheral neuropathy', Clinical Neurophysiology, 160, pp. 12 - 18, http://dx.doi.org/10.1016/j.clinph.2024.02.002

Dhanapalaratnam R; Issar T; Lee ATK; Poynten AM; Milner KL; Kwai NCG; Krishnan AV, 2024, 'Glucagon-like peptide-1 receptor agonists reverse nerve morphological abnormalities in diabetic peripheral neuropathy', Diabetologia, 67, pp. 561 - 566, http://dx.doi.org/10.1007/s00125-023-06072-6

Asiedu K; Tummanapalli SS; Alotaibi S; Wang LL; Dhanapalaratnam R; Kwai N; Poynten A; Markoulli M; Krishnan AV, 2024, 'Impact of SGLT2 Inhibitors on Corneal Nerve Morphology and Dendritic Cell Density in Type 2 Diabetes', Ocular Immunology and Inflammation, 32, pp. 234 - 241, http://dx.doi.org/10.1080/09273948.2023.2263789

Chiang JCB; Roy M; Kim J; Markoulli M; Krishnan AV, 2023, 'In-vivo corneal confocal microscopy: Imaging analysis, biological insights and future directions', Communications Biology, 6, http://dx.doi.org/10.1038/s42003-023-05005-8

Md Isa NA; Tummanapalli SS; Chiang JCB; Krishnan AV; Zagami AS; Papas EB; Markoulli M; Spira K, 2023, 'Neuropathic changes in corneal nerve endings—A potential objective biomarker for migraine frequency and response to treatment', Headache, 63, pp. 1327 - 1329, http://dx.doi.org/10.1111/head.14630

Asiedu K; Alotaibi S; Krishnan AV; Kwai N; Poynten A; Markoulli M; Dhanapalaratnam R, 2023, 'Chronic Kidney Disease Has No Impact on Tear Film Substance P Concentration in Type 2 Diabetes', Biomedicines, 11, http://dx.doi.org/10.3390/biomedicines11092368

Dhanapalaratnam R; Issar T; Krishnan AV, 2023, 'Hindsight for ultrasound imaging/measurement of the tibial nerve (answer)', European Journal of Neurology, 30, pp. 564, http://dx.doi.org/10.1111/ene.15619

Asiedu K; Krishnan AV; Kwai N; Poynten A; Markoulli M, 2023, 'Conjunctival microcirculation in ocular and systemic microvascular disease', Clinical and Experimental Optometry, 106, pp. 694 - 702, http://dx.doi.org/10.1080/08164622.2022.2151872

Asiedu K; Markoulli M; Tummanapalli SS; Chiang JCB; Alotaibi S; Wang LL; Dhanapalaratnam R; Kwai N; Poynten A; Krishnan AV, 2023, 'Impact of Chronic Kidney Disease on Corneal Neuroimmune Features in Type 2 Diabetes', Journal of Clinical Medicine, 12, http://dx.doi.org/10.3390/jcm12010016

Dhanapalaratnam R; Issar T; Poynten AM; Milner KL; Kwai NCG; Krishnan AV, 2022, 'Diagnostic accuracy of nerve ultrasonography for the detection of peripheral neuropathy in type 2 diabetes', European Journal of Neurology, 29, pp. 3571 - 3579, http://dx.doi.org/10.1111/ene.15534

Chiang JCB; Khou V; Tavakoli A; Park SB; Goldstein D; Krishnan AV; Markoulli M, 2022, 'Reproducibility and Reliability of Subbasal Corneal Nerve Parameters of the Inferior Whorl in the Neurotoxic and Healthy Cornea', Cornea, 41, pp. 1487 - 1494, http://dx.doi.org/10.1097/ICO.0000000000002947

Asiedu K; Dhanapalaratnam R; Krishnan AV; Kwai N; Poynten A; Markoulli M, 2022, 'Impact of Peripheral and Corneal Neuropathy on Markers of Ocular Surface Discomfort in Diabetic Chronic Kidney Disease', Optometry and Vision Science, 99, pp. 807 - 816, http://dx.doi.org/10.1097/OPX.0000000000001955

Chiang JCB; Goldstein D; Trinh T; Au K; Park SB; Krishnan AV; Markoulli M, 2022, 'Tear film substance P in patients treated with neurotoxic chemotherapy', Experimental Eye Research, 224, http://dx.doi.org/10.1016/j.exer.2022.109253

Liao J; Kang A; Xia C; Young T; Di Tanna GL; Arnott C; Pollock C; Krishnan AV; Agarwal R; Bakris G; Charytan DM; de Zeeuw D; Heerspink HJL; Levin A; Neal B; Wheeler DC; Zhang H; Zinman B; Mahaffey KW; Perkovic V; Jardine MJ; Smyth B, 2022, 'The impact of canagliflozin on the risk of neuropathy events: A post-hoc exploratory analysis of the CREDENCE trial', Diabetes and Metabolism, 48, pp. 101331, http://dx.doi.org/10.1016/j.diabet.2022.101331

Chiang JCB; Arnold R; Dhanapalaratnam R; Markoulli M; Krishnan AV, 2022, 'Current and Emerging Pharmacotherapeutic Interventions for the Treatment of Peripheral Nerve Disorders', Pharmaceuticals, 15, pp. 607, http://dx.doi.org/10.3390/ph15050607

Issar T; Walker S; Arnold R; Poynten AM; Endre ZH; Krishnan AV, 2022, 'Peripheral nerve morphology and intraneural blood flow in chronic kidney disease with and without diabetes', Muscle and Nerve, 65, pp. 603 - 607, http://dx.doi.org/10.1002/mus.27513

Asiedu K; Markoulli M; Bonini S; Bron AJ; Dogru M; Kwai N; Poynten A; Willcox MDP; Krishnan AV, 2022, 'Tear film and ocular surface neuropeptides: Characteristics, synthesis, signaling and implications for ocular surface and systemic diseases', Experimental Eye Research, 218, http://dx.doi.org/10.1016/j.exer.2022.108973

Krishnan A; Ellenberger KA; Phetsouphanh C; Kelleher AP; Matthews GV; Darley DR; Holloway CJ, 2022, 'Myocardial fibrosis occurs in non-hospitalised patients with chronic symptoms after COVID-19', IJC Heart and Vasculature, 39, http://dx.doi.org/10.1016/j.ijcha.2022.100964

Arnold R; Pianta TJ; Issar T; Kirby A; Scales CMK; Kwai NCG; Endre Z; Krishnan AV, 2022, 'Peripheral neuropathy: An important contributor to physical limitation and morbidity in stages 3 and 4 chronic kidney disease', Nephrology Dialysis Transplantation, 37, pp. 713 - 719, http://dx.doi.org/10.1093/ndt/gfab043

Hensen HA; Carberry JC; Krishnan AV; Osman AM; Mosch AMH; Toson B; Tay KL; Eckert DJ, 2022, 'Impaired pharyngeal reflex responses to negative pressure: a novel cause of sleep apnea in multiple sclerosis', Journal of Applied Physiology, 132, pp. 815 - 823, http://dx.doi.org/10.1152/japplphysiol.00240.2021

Klisser J; Tummanapalli SS; Kim J; Chiang JCB; Khou V; Issar T; Naduvilath T; Poynten AM; Markoulli M; Krishnan AV, 2022, 'Automated analysis of corneal nerve tortuosity in diabetes: implications for neuropathy detection', Clinical and Experimental Optometry, 105, pp. 487 - 493, http://dx.doi.org/10.1080/08164622.2021.1940875

Dhanapalaratnam R; Markoulli M; Krishnan AV, 2022, 'Disorders of vision in multiple sclerosis', Clinical and Experimental Optometry, 105, pp. 3 - 12, http://dx.doi.org/10.1080/08164622.2021.1947745

Chiang JCB; Krishnan AV; Goldstein D; Markoulli M, 2022, 'The Impact of Post-Tear Collection Storage on Tear Film Substance P Concentration', Current Eye Research, 47, pp. 1116 - 1120, http://dx.doi.org/10.1080/02713683.2022.2067565

Chiang JCB; Goldstein D; Trinh T; Au K; Park SB; Krishnan AV; Markoulli M, 2021, 'A cross-sectional study of ocular surface discomfort and corneal nerve dysfunction after paclitaxel treatment for cancer', Scientific Reports, 11, pp. 1786, http://dx.doi.org/10.1038/s41598-021-81398-y

Chiang JCB; Goldstein D; Tavakoli A; Trinh T; Klisser J; Lewis CR; Friedlander M; Naduvilath TJ; Au K; Park SB; Krishnan AV; Markoulli M, 2021, 'Corneal dendritic cells and the subbasal nerve plexus following neurotoxic treatment with oxaliplatin or paclitaxel', Scientific Reports, 11, pp. 22884, http://dx.doi.org/10.1038/s41598-021-02439-0

Carter S; Hensen H; Krishnan A; Chiang A; Carberry J; Eckert D, 2021, 'P019 Obstructive sleep apnoea endotypes in people with multiple sclerosis', SLEEP Advances, 2, pp. A27 - A28, http://dx.doi.org/10.1093/sleepadvances/zpab014.067

Issar T; Kwai NCG; Poynten AM; Arnold R; Milner KL; Krishnan AV, 2021, 'Effect of exenatide on peripheral nerve excitability in type 2 diabetes', Clinical Neurophysiology, 132, pp. 2532 - 2539, http://dx.doi.org/10.1016/j.clinph.2021.05.033

Kang A; Arnold R; Gallagher M; Snelling P; Green J; Fernando M; Kiernan MC; Hand S; Grimley K; Burman J; Heath A; Rogers K; Bhattacharya A; Smyth B; Bradbury T; Hawley C; Perkovic V; Krishnan AV; Jardine MJ, 2021, 'Effect of hemodiafiltration on the progression of neuropathy with kidney failure: A randomized controlled trial', Clinical Journal of the American Society of Nephrology, 16, pp. 1365 - 1375, http://dx.doi.org/10.2215/CJN.17151120

Chiang JCB; Goldstein D; Park SB; Krishnan AV; Markoulli M, 2021, 'Corneal nerve changes following treatment with neurotoxic anticancer drugs', Ocular Surface, 21, pp. 221 - 237, http://dx.doi.org/10.1016/j.jtos.2021.06.007

Issar T; Tummanapalli SS; Borire AA; Kwai NCG; Poynten AM; Arnold R; Markoulli M; Krishnan AV, 2021, 'Impact of the metabolic syndrome on peripheral nerve structure and function in type 2 diabetes', European Journal of Neurology, 28, pp. 2074 - 2082, http://dx.doi.org/10.1111/ene.14805

Liao J; Kang A; Xia C; Arnott C; Di Tanna GL; Krishnan AV; Pollock CA; Agarwal R; Bakris G; Heerspink HL; Levin A; De Zeeuw D; Neal B; Zhang H; Wheeler DC; Zinman B; Mahaffey KW; Perkovic V; Jardine MJ; Smyth B, 2021, 'The Impact of Canagliflozin on the Risk of Neuropathy Events: Results from the CREDENCE Trial', DIABETES, 70, http://dx.doi.org/10.2337/db21-131-LB

Trinh T; Park SB; Murray J; Pickering H; Lin CSY; Martin A; Friedlander M; Kiernan MC; Goldstein D; Krishnan AV, 2021, 'Neu-horizons: neuroprotection and therapeutic use of riluzole for the prevention of oxaliplatin-induced neuropathy—a randomised controlled trial', Supportive Care in Cancer, 29, pp. 1103 - 1110, http://dx.doi.org/10.1007/s00520-020-05591-x

Chiang JCB; Goldstein D; Trinh T; Au K; Mizrahi D; Muhlmann M; Crowe P; O’neill S; Edwards K; Park SB; Krishnan AV; Markoulli M, 2021, 'A cross-sectional study of sub-basal corneal nerve reduction following neurotoxic chemotherapy', Translational Vision Science and Technology, 10, pp. 1 - 11, http://dx.doi.org/10.1167/tvst.10.1.24

Habeych ME; Trinh T; Issar T; Kwai NCG; Krishnan AV, 2020, 'Motor unit number estimation of facial muscles using the M Scan-Fit method', Muscle and Nerve, 62, pp. 555 - 558, http://dx.doi.org/10.1002/mus.27010

Issar T; Tummanapalli SS; Kwai NCG; Chiang JCB; Arnold R; Poynten AM; Markoulli M; Krishnan AV, 2020, 'Associations between acute glucose control and peripheral nerve structure and function in type 1 diabetes', Diabetic Medicine, 37, pp. 1553 - 1560, http://dx.doi.org/10.1111/dme.14306

Hossain MJ; Kendig MD; Wild BM; Issar T; Krishnan AV; Morris MJ; Arnold R, 2020, 'Evidence of altered peripheral nerve function in a rodent model of diet-induced prediabetes', Biomedicines, 8, pp. 313, http://dx.doi.org/10.3390/biomedicines8090313

Tummanapalli SS; Issar T; Kwai N; Pisarcikova J; Poynten AM; Krishnan AV; Willcox MDP; Markoulli M, 2020, 'A Comparative Study on the Diagnostic Utility of Corneal Confocal Microscopy and Tear Neuromediator Levels in Diabetic Peripheral Neuropathy', Current Eye Research, 45, pp. 921 - 930, http://dx.doi.org/10.1080/02713683.2019.1705984

Chiang JCB; Zahari I; Markoulli M; Krishnan AV; Park SB; Semmler A; Goldstein D; Edwards K, 2020, 'The impact of anticancer drugs on the ocular surface', Ocular Surface, 18, pp. 403 - 417, http://dx.doi.org/10.1016/j.jtos.2020.03.008

Tummanapalli SS; Willcox MDP; Issar T; Kwai N; Poynten AM; Krishnan AV; Pisarcikova J; Markoulli M, 2020, 'The Effect of Age, Gender and Body Mass Index on Tear Film Neuromediators and Corneal Nerves', Current Eye Research, 45, pp. 411 - 418, http://dx.doi.org/10.1080/02713683.2019.1666998

Kandula T; Farrar MA; Cohn RJ; Carey KA; Johnston K; Kiernan MC; Krishnan AV; Park SB, 2020, 'Changes in long term peripheral nerve biophysical properties in childhood cancer survivors following neurotoxic chemotherapy', Clinical Neurophysiology, 131, pp. 783 - 790, http://dx.doi.org/10.1016/j.clinph.2019.12.411

Issar T; Yan A; Kwai NCG; Poynten AM; Borire AA; Arnold R; Krishnan AV, 2020, 'Altered peripheral nerve structure and function in latent autoimmune diabetes in adults', Diabetes/Metabolism Research and Reviews, 36, http://dx.doi.org/10.1002/dmrr.3260

Tummanapalli SS; Issar T; Kwai N; Poynten A; Krishnan AV; Willcox M; Markoulli M, 2020, 'Erratum to ‘Association of corneal nerve loss with markers of axonal ion channel dysfunction in type 1 diabetes’. (Clinical Neurophysiology (2020) 131(1) (145–154), (S1388245719312726), (10.1016/j.clinph.2019.09.029))', Clinical Neurophysiology, 131, pp. 780, http://dx.doi.org/10.1016/j.clinph.2020.01.001

Yan A; Issar T; Tummanapalli SS; Markoulli M; Kwai NCG; Poynten AM; Krishnan AV, 2020, 'Relationship between corneal confocal microscopy and markers of peripheral nerve structure and function in Type 2 diabetes', Diabetic Medicine, 37, pp. 326 - 334, http://dx.doi.org/10.1111/dme.13952

Borire AA; Issar T; Kwai NC; Visser LH; Simon NG; Poynten AM; Kiernan MC; Krishnan AV, 2020, 'Sonographic assessment of nerve blood flow in diabetic neuropathy', Diabetic Medicine, 37, pp. 343 - 349, http://dx.doi.org/10.1111/dme.14085

Tummanapalli SS; Issar T; Kwai N; Poynten A; Krishnan AV; Willcox M; Markoulli M, 2020, 'Association of corneal nerve loss with markers of axonal ion channel dysfunction in type 1 diabetes', Clinical Neurophysiology, 131, pp. 145 - 154, http://dx.doi.org/10.1016/j.clinph.2019.09.029

Tummanapalli SS; Issar T; Yan A; Kwai N; Poynten AM; Krishnan AV; Willcox MDP; Markoulli M, 2020, 'Corneal nerve fiber loss in diabetes with chronic kidney disease', Ocular Surface, 18, pp. 178 - 185, http://dx.doi.org/10.1016/j.jtos.2019.11.010

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