By Professor Bruce James Brew

Journal articles

Chan P; Brew BJ, 2014, 'HIV associated neurocognitive disorders in the modern antiviral treatment era: prevalence, characteristics, biomarkers, and effects of treatment', Current HIV/AIDS reports, 11, pp. 317 - 324, http://dx.doi.org/10.1007/s11904-014-0221-0

Dwyer R; Wenhui L; Cysique L; Brew BJ; Lal L; Bain P; Wesselingh S; Wright EJ, 2014, 'Symptoms of depression and rates of neurocognitive impairment in HIV positive patients in Beijing, China', Journal of Affective Disorders, 162, pp. 89 - 95, http://dx.doi.org/10.1016/j.jad.2014.03.038

Braidy N; Brew BJ; Inestrosa NC; Chung R; Sachdev P; Guillemin GJ, 2014, 'Changes in Cathepsin D and Beclin-1 mRNA and protein expression by the excitotoxin quinolinic acid in human astrocytes and neurons', Metabolic Brain Disease, 29, pp. 873 - 883, http://dx.doi.org/10.1007/s11011-014-9557-9

Lu GM; Brew BJ; Siefried KJ; Draper B; Cysique LA, 2014, 'Is the HIV dementia scale a reliable tool for assessing HIV-relatedneurocognitive decline?', Journal of AIDS and Clinical Research, 5, http://dx.doi.org/10.4172/2155-6113.1000269

Cysique LA; Brew BJ, 2014, 'The effects of HIV and aging on brain functions: Proposing a research framework and update on last 3 years' findings', Current Opinion in HIV and AIDS, 9, pp. 355 - 364, http://dx.doi.org/10.1097/COH.0000000000000078

Brew BJ; Chan P, 2014, 'Update on HIV dementia and HIV-associated neurocognitive disorders', Current Neurology and Neuroscience Reports, 14, http://dx.doi.org/10.1007/s11910-014-0468-2

Power C; Brew BJ, 2014, 'HIV-1 infection and the nervous system-a shifting target.', Current Opinion in HIV and AIDS, 9, pp. 515 - 516, http://dx.doi.org/10.1097/COH.0000000000000113

Cysique LA; Heaton RK; Kamminga J; Lane T; Gates TM; Moore DM; Hubner E; Carr A; Brew BJ, 2014, 'HIV-associated neurocognitive disorder in Australia: a case of a high-functioning and optimally treated cohort and implications for international neuroHIV research', Journal of NeuroVirology, 20, pp. 258 - 268, http://dx.doi.org/10.1007/s13365-014-0242-x

Crossley KM; Brew BJ, 2013, 'Neurological complications in controlled HIV infection', Current Infectious Disease Reports, 15, pp. 564 - 568, http://dx.doi.org/10.1007/s11908-013-0375-8

Braidy N; Lim CK; Grant R; Brew BJ; Guillemin GJ, 2013, 'Serum nicotinamide adenine dinucleotide levels through disease course in multiple sclerosis', Brain Research, 1537, pp. 267 - 272, http://dx.doi.org/10.1016/j.brainres.2013.08.025

Clifford DB; Nath A; Cinque P; Brew BJ; Zivadinov R; Gorelik L; Zhao Z; Duda P, 2013, 'A study of mefloquine treatment for progressive multifocal leukoencephalopathy: Results and exploration of predictors of PML outcomes', Journal of NeuroVirology, 19, pp. 351 - 358, http://dx.doi.org/10.1007/s13365-013-0173-y

Grund B; Wright EJ; Brew BJ; Price RW; Roediger MP; Bain MP; Hoy JF; Shlay JC; Vjecha MJ; Robertson KR, 2013, 'Improved neurocognitive test performance in both arms of the SMART study: Impact of practice effect', Journal of NeuroVirology, 19, pp. 383 - 392, http://dx.doi.org/10.1007/s13365-013-0190-x

LeWitt PA; Boroojerdi B; Surmann E; Poewe W, 2013, 'Rotigotine transdermal system for long-term treatment of patients with advanced Parkinson's disease: results of two open-label extension studies, CLEOPATRA-PD and PREFER', JOURNAL OF NEURAL TRANSMISSION, 120, pp. 1069 - 1081, http://dx.doi.org/10.1007/s00702-012-0925-5

Peluso MJ; Meyerhoff DJ; Price RW; Peterson J; Lee E; Young AC; Walter R; Fuchs D; Brew BJ; Cinque P; Robertson K; Hagberg L; Zetterberg H; Gisslén M; Spudich S, 2013, 'Cerebrospinal fluid and neuroimaging biomarker abnormalities suggest early neurological injury in a subset of individuals during primary HIV infection', Journal of Infectious Diseases, 207, pp. 1703 - 1712, http://dx.doi.org/10.1093/infdis/jit088

Mora-Peris B; MacKie NE; Suan D; Cooper DA; Brew BJ; Winston A, 2013, 'Raltegravir resistance in the cerebrospinal fluid', Infection, 41, pp. 731 - 734, http://dx.doi.org/10.1007/s15010-013-0409-z

, 2013, 'The NRTIs Lamivudine, Stavudine and Zidovudine Have Reduced HIV-1 Inhibitory Activity in Astrocytes', PLoS ONE, http://dx.doi.org/10.1371/journal.pone.0062196

Antinori A; Arendt G; Grant I; Letendre S; Muñoz-Moreno JA; Eggers C; Brew B; Brouillette MJ; Bernal-Cano F; Carvalhal A; Christo PP; Cinque P; Cysique L; Ellis R; Everall I; Gasnault J; Husstedt I; Korten V; Machala L; Obermann M; Ouakinin S; Podzamczer D; Portegies P; Rackstraw S; Rourke S; Sherr L; Streinu-Cercel A; Winston A; Wojna V; Yazdanpannah Y; Arbess G; Baril JG; Begovac J; Bergin C; Bonfanti P; Bonora S; Brinkman K; Canestri A; Cholewinska-Szymanska G; Chowers M; Cooney J; Corti M; Doherty C; Elbirt D; Esser S; Florence E; Force G; Gill J; Goffard JC; Harrer T; Li P; Van De Kerckhove L; Knecht G; Matsushita S; Matulionyte R; McConkey S; Mouglignier A; Oka S; Penalva A; Riesenberg K; Sambatakou H; Tozzi V; Vassallo M; Wetterberg P; Drapato AW, 2013, 'Assessment, diagnosisand treatment of Human Immunodeficiency Virus (HIV)-associated neurocognitive disorders (HAND): A consensus report of the mind exchange program', Clinical Infectious Diseases, 56, pp. 1004 - 1017, http://dx.doi.org/10.1093/cid/cis975

Brew BJ; Gray L; Lewin S; Churchill M, 2013, 'Is specific HIV eradication from the brain possible or needed?', Expert Opinion on Biological Therapy, 13, pp. 403 - 409, http://dx.doi.org/10.1517/14712598.2013.748029

Brew BJ; McLean CA; Major EO, 2013, 'Progressive multifocal leukoencephalopathy caused by BK virus?', Medical Journal of Australia, 198, pp. 179 - 180, http://dx.doi.org/10.5694/mja12.11798

Joseph J; Achim CL; Boivin MJ; Brew BJ; Clifford DB; Colosi DA; Ellis RJ; Heaton RK; Gallo-Diop A; Grant I; Kanmogne GD; Kumar M; Letendre S; Marcotte TD; Nath A; Pardo CA; Paul RH; Pulliam L; Robertson K; Royal W; Sacktor N; Sithinamsuwan P; Smith DM; Valcour V; Wigdahl B; Wood C, 2013, 'Global NeuroAIDS roundtable', Journal of NeuroVirology, 19, pp. 1 - 9, http://dx.doi.org/10.1007/s13365-012-0143-9

Brown S; Simpson DM; Moyle G; Brew BJ; Schifitto G; Larbalestier N; Orkin C; Fisher M; Vanhove GF; Tobias JK, 2013, 'NGX-4010, a capsaicin 8% patch, for the treatment of painful HIV-associated distal sensory polyneuropathy: Integrated analysis of two phase III, randomized, controlled trials', AIDS Research and Therapy, 10, http://dx.doi.org/10.1186/1742-6405-10-5

Jones SP; Guillemin GJ; Brew BJ, 2013, 'The kynurenine pathway in stem cell biology', International Journal of Tryptophan Research, 6, pp. 57 - 66, http://dx.doi.org/10.4137/IJTR.S12626

Wu W; Nicolazzo JA; Wen L; Chung RS; Stankovic RK; Bao SS; Lim CKE; Brew BJ; Cullen KM; Guillemin GJ, 2013, 'Expression of Tryptophan 2,3-Dioxygenase and Production of Kynurenine Pathway Metabolites in Triple Transgenic Mice and Human Alzheimer's Disease Brain', PLoS One, 8, pp. Article numbere59749, http://dx.doi.org/10.1371/journal.pone.0059749

Sasson SC; Oon A; Chagantri J; Brew BJ; Carr A, 2013, 'Posterior reversible encephalopathy syndrome (PRES) in an HIV-1 infected patient with disseminated varicella zoster virus: a case report', BMC Infectious Diseases, 13, pp. 396 - 396, http://dx.doi.org/10.1186/1471-2334-13-396

Braidy N; Lim CK; Guillemin GJ; Grant R; Brew BJ, 2013, 'Serum nicotinamide adenine dinucleotide levels through disease course in multiple sclerosis', Brain Research, http://dx.doi.org/10.1016/j.brainres.2013.08.025

Kamminga J; Cysique LA; Lu G; Batchelor J; Brew BJ, 2013, 'Validity of Cognitive Screens for HIV-Associated Neurocognitive Disorder: A Systematic Review and an Informed Screen Selection Guide', Current HIV/AIDS Reports, 10, pp. 342 - 355, http://dx.doi.org/10.1007/s11904-013-0176-6

Adams S; Braidy N; Bessede A; Brew BJ; Grant R; Teo C; Guillemin GJ, 2012, 'Correction: The kynurenine pathway in brain tumor pathogenesis (Cancer Research (2012) 72, (5649-5657))', Cancer Research, 72, pp. 6524, http://dx.doi.org/10.1158/0008-5472.CAN-12-4230

Lim CK; Yap MMC; Kent SJ; Gras G; Samah B; Batten JC; De Rose R; Heng B; Brew BJ; Guillemin GJ, 2012, 'Characterization of the Kynurenine pathway and quinolinic acid production in macaque macrophages', International Journal of Tryptophan Research, 6, pp. 7 - 19, http://dx.doi.org/10.4137/IJTR.S11789

Cysique L; Brew B, 2012, 'Characteristics of neurocognitive decline in virally-suppressed middle-aged HIV plus individuals', JOURNAL OF NEUROVIROLOGY, 18, pp. 26 - 26, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000304487800054&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Peluso M; Price R; Peterson J; Lee E; Fuchs D; Brew B; Cinque P; Hagberg L; Zetterberg H; Gisslen M; Spudich S, 2012, 'Primary HIV-1 infection is characterized by elevation of cerebrospinal fluid biomarkers indicating early neuronal damage', JOURNAL OF NEUROVIROLOGY, 18, pp. 83 - 84, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000304487800171&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Gray L; Tachedjian G; Ellett A; Roche M; Brew B; Turville S; Wesselingh S; Gorry P; Churchill M, 2012, 'Reduced Effectiveness of the NRTIs d4T and AZT in Astrocytes: Implications for Neuro-cART', JOURNAL OF NEUROVIROLOGY, 18, pp. 42 - 43, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000304487800089&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Chew C; Cysique L; Brew B; Price P, 2012, 'Relationships between genetic markers of neuroinflammation, neurodegeneration and neurocognitive impairment in controlled HIV infection', JOURNAL OF NEUROVIROLOGY, 18, pp. 23 - 24, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000304487800048&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Brew BJ; Thompson J, 2012, 'Epilepsy: Issues with antiepileptic drug use in HIV-infected patients', Nature Reviews Neurology, 8, pp. 187 - 188, http://dx.doi.org/10.1038/nrneurol.2012.36

Mothobi NZ; Brew BJ, 2012, 'Neurocognitive dysfunction in the highly active antiretroviral therapy era', Current Opinion in Infectious Diseases, 25, pp. 4 - 9, http://dx.doi.org/10.1097/QCO.0b013e32834ef586

Clifford D; Simpson D; Brown S; Moyle G; Brew BJ; Conway B; Tobias J; Vanhove J, 2012, 'A Randomized, Double-Blind, Controlled Study of NGX-4010, a Capsaicin 8% Dermal Patch, for the Treatment of Painful HIV-Associated Distal Sensory Polyneuropathy', JAIDS: Journal of Acquired Immune Deficiency Syndromes, 59, pp. 126 - 133, http://ovidsp.tx.ovid.com/sp-3.8.1a/ovidweb.cgi?QS2=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

Cruse B; Cysique LA; Markus R; Brew BJ, 2012, 'Cerebrovascular disease in HIV-infected individuals in the era of highly active antiretroviral therapy', Journal of Neurovirology, 18, pp. 264 - 276, http://dx.doi.org/10.1007/s13365-012-0092-3

Lee M-C; Ting KK; Adams S; Brew BJ; Chung R; Guillemin GJ, 2012, 'Characterisation of the expression of NMDA receptors in human primary astrocytes', Neurology, Psychiatry and Brain Research, 18, pp. 57 - 57, http://dx.doi.org/10.1016/j.npbr.2012.02.017

Lane TA; Batchelor J; Brew BJ; Cysique LA, 2012, 'Facial emotional processing in HIV infection: relation to neurocognitive and neuropsychiatric status', Neuropsychology, 26, pp. 713 - 722, http://dx.doi.org/10.1037/a0029964

Cysique L; Bain ; Lane ; Brew B, 2012, 'Management issues in HIV-associated neurocognitive disorders', Neurobehavioral HIV Medicine, pp. 63 - 63, http://dx.doi.org/10.2147/nbhiv.s30466

Blair N; Brew BJ; Halpern J, 2012, 'Natalizumab-associated PML identified in the presymptomatic phase using MRI surveillance', Neurology, 78, pp. 507 - 508, http://ovidsp.tx.ovid.com/sp-3.8.1a/ovidweb.cgi?QS2=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

Kandanearatchi ; Brew BJ, 2012, 'The kynurenine pathway and quinolinic acid: Pivotal roles in HIV associated neurocognitive disorders', FEBS Journal, 279, pp. 1366 - 1374, http://dx.doi.org/10.1111/j.1742-4658.2012.08500.x

Adams S; Braidy N; Bess A; Brew BJ; Grant RS; Teo C; Guillemin GJ, 2012, 'The kynurenine pathway in brain tumor pathogenesis', Cancer research, 72, pp. 5649 - 5657, http://dx.doi.org/10.1158/0008-5472.CAN-12-0549

Maruszak H; Brew BJ; Giovannoni G; Gold J, 2011, 'Could antiretroviral drugs be effective in multiple sclerosis? A case report', European Journal of Neurology, 18, http://dx.doi.org/10.1111/j.1468-1331.2011.03430.x

Jawaid A; Pradeep V; Shamsi A; Schulz PE, 2011, 'Cardiovascular risk factors associated with lower baseline cognitive performance in HIV-positive persons.', Neurology, 77, pp. 406 - 407, http://dx.doi.org/10.1212/WNL.0b013e3182246ffb

Wright E; Grund B; Robertson K; Brew B; Price R, 2011, 'Reply from the authors', Neurology, 77, pp. 407, http://dx.doi.org/10.1212/WNL.0b013e3182246fb2

Wright E; Grund B; Robertson K; Brew B; Price R, 2011, 'CARDIOVASCULAR RISK FACTORS ASSOCIATED WITH LOWER BASELINE COGNITIVE PERFORMANCE IN HIV-POSITIVE PERSONS Reply', NEUROLOGY, 77, pp. 407 - 407, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000293123300026&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Ng K; Kumar KR; Brew BJ; Burke D, 2011, 'Axonal excitability in viral polyneuropathy and nucleoside neuropathy in HIV patients', Journal of Neurology Neurosurgery and Psychiatry, 82, pp. 978 - 980, http://dx.doi.org/10.1136/jnnp.2009.203091

Cysique LA; Waters EK; Brew BJ, 2011, 'Central nervous system antiretroviral efficacy in HIV infection: a qualitative and quantitative review and implications for future research', BMC NEUROLOGY, 11, pp. 148 - 158

Spudich S; Gisslen M; Hagberg L; Lee E; Liegler T; Brew BJ; Fuchs A; Tambussi G; Cinque P; Hecht FM; Price R, 2011, 'Central nervous system immune activation characterizes primary HIV-1 infection even in subjects with minimal cerebrospinal fluid viral burden', Journal of Infectious Diseases, 204, pp. 753 - 760, http://dx.doi.org/10.1093/infdis/jir387

Chen Y; Brew BJ; Guillemin GJ, 2011, 'Characterization of the kynurenine pathway in NSC-34 cell line: implications for amyotrophic lateral sclerosis', Journal of Neurochemistry, 118, pp. 816 - 825, http://dx.doi.org/10.1111/j.1471-4159.2010.07159.x/abstract;jsessionid=83A44016D40A402F78AD97483FD7AAFE.d02t04?systemMessage=Wiley+Online+Library+will+be+disrupted+14+May+from+10-12+BST+for+monthly+maintenance

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