By Professor Bruce James Brew

Preprints

Suzuki K; Levert A; Yoo E; Abohashem S; Zaunders J; Cysique L; Ode H; Iwatani Y; Tawakol A; Hsue P; Chow F; Brew B, 2026, Transcriptionally Active HIV Reservoirs Enriched for Interferon-Inducible APOBEC3-Related Mutational Signatures Associate with Arterial Inflammation, http://dx.doi.org/10.64898/2026.06.03.729898

Suzuki K; Levert A; Yoo E; Matsuda M; Ishida T; Cysique L; Zaunders J; Deveson I; Barton K; Ode H; Iwatani Y; Brew B, 2026, Transcriptionally Active HIV Reservoirs Enriched for Interferon-Inducible APOBEC3-Related Mutational Signatures Associate with Reduced Neuroaxonal Integrity, http://dx.doi.org/10.64898/2026.06.02.729658

Suzuki K; Zaunders J; Gates T; Levert A; Butterly S; Liu Z; Ishida T; Huang C-S; Palmer S; Rae C; Jugé L; Cysique L; Brew B, 2021, Elevation of cell-associated HIV-1 RNA transcripts in CSF CD4+ T cells, despite suppressive antiretroviral therapy, is linked to in vivo brain injury, http://dx.doi.org/10.1101/2021.12.22.21268288

Nir TM; Fouche J-P; Ananworanich J; Ances BM; Boban J; Brew BJ; Chaganti J; Chang L; Ching CRK; Cysique LA; Ernst T; Faskowitz J; Gupta V; Harezlak J; Heaps-Woodruff JM; Hinkin CH; Hoare J; Joska JA; Kallianpur KJ; Kuhn T; Lam HY; Law M; Lebrun-Frenay C; Levine AJ; Mondot L; Nakamoto BK; Navia BA; Pennec X; Porges EC; Shikuma CM; Thames AD; Valcour V; Vassallo M; Woods AJ; Thompson PM; Cohen RA; Paul R; Stein DJ; Jahanshad N, 2019, Common Brain Volume Signatures Associated with Immunosuppression and Viral Load in Over 1000 Adults Living with HIV Across 5 Continents: Findings from the ENIGMA-HIV Working Group, http://dx.doi.org/10.2139/ssrn.3439553

Chaganti JR; Talekar TK; Brew BJ, Asymmetrical glymphatic dysfunction in patients with Long Covid associated neurocognitive impairment- Correlation with BBB disruption, http://dx.doi.org/10.21203/rs.3.rs-4551571/v1

Brew B; Faux SG; Blanchard E, Effectiveness of a Smartwatch App in Detecting Induced Falls: Observational Study (Preprint), http://dx.doi.org/10.2196/preprints.30121

Chaganti Franzcr J; Marripudi K; Staub L; Gates TM; Moffat K; Brew BJ, Imaging Correlates of the Blood Brain Barrier Disruption in HIV Associated Neurocognitive Disorder and Therapeutic Implications, http://dx.doi.org/10.2139/ssrn.3285744

Phetsouphanh C; Jacka B; Ballouz S; Jackson KJ; Wilson DB; Manandhar B; Klemm V; Tan H-X; Wheatley A; Aggarwal A; Akerman A; Milogiannakis V; Starr M; Cunningham P; Turville SG; Kent SJ; Byrne A; Brew BJ; Darley DR; Dore GJ; Kelleher AD; Matthews GV, Improvement of immune dysregulation and health-related quality of life in individuals with long COVID at 24-months following SARS-CoV-2 infection, http://dx.doi.org/10.1101/2023.08.27.23294704

Darley ; Dore G; Byrne A; Plit M; Brew B; Kelleher A; Matthews G, Limited recovery from post-acute sequelae of SARS-CoV-2 (PASC) at eight months in a prospective cohort, http://dx.doi.org/10.1101/2021.03.29.21254211

Wilson MR; O’Donovan BD; Gelfand JM; Sample HA; Chow FC; Betjemann JP; Shah MP; Richie MB; Gorman MP; Hajj-Ali RA; Calabrese LH; Zorn KC; Greenlee JE; Blum JH; Green G; Khan LM; Banerji D; Langelier C; Bryson-Cahn C; Harrington W; Lingappa JR; Shanbhag NM; Green AJ; Brew BJ; Soldatos A; Strnad L; Doernberg SB; Jay CA; Douglas V; Josephson SA; DeRisi JL, Metagenomics for chronic meningitis: clarifying interpretation and diagnosis, http://dx.doi.org/10.1101/213561

Macfarlane S; Grimmer T; Teo K; O’Brien TJ; Woodward M; Grunfeld J; Mander A; Brew BJ; Morris P; Short C; Kurrle S; Lai R; Bharadwaj S; Drysdale P; Sturm J; Lewis SJG; Kalafatis C; Sharif S; Mannering N; MacSweeney JE; Pearson S; Evans C; Bhatt N; Connell S; Lynch J; Dautzenberg PL; Prins N; Frölich L; Tacik P; Peters O; Henri-Bhargava A; Pasternak SH; Frank A; Chertkow H; Ingram J; Hsiung G-YR; Tartaglia C; Cohen S; Courrèges O; Villa LM; Gordon E; Guizard N; Edwards J; Kellmeyer T; Lopez-Talavera JC; Gould DS; Liedtke W; Jin K; Chezem WR; Missling CU; Gabelle A; Sabbagh MN, Oral Blarcamesine Phase IIb/III Trial Confirms Identified Precision Medicine Patient Population – Significant Broad Clinical and Quality of Life Improvements for Early Alzheimer’s Disease Patients, http://dx.doi.org/10.1101/2025.09.27.25336656

Cysique LA; Jakabek D; Bracken SG; Allen-Davidian Y; Heng B; Chow S; Dehhaghi M; Pires AS; Darley DR; Byrne A; Phetsouphanh C; Kelleher A; Dore GJ; Matthews GV; Guillemin GJ; Brew BJ, Post-acute COVID-19 cognitive impairment and decline uniquely associate with kynurenine pathway activation: a longitudinal observational study, http://dx.doi.org/10.1101/2022.06.07.22276020

Nir TM; Fouche J-P; Ananworanich J; Ances BM; Boban J; Brew BJ; Chang L; Chaganti JR; Ching CRK; Cysique LA; Ernst T; Faskowitz J; Gupta V; Harezlak J; Heaps-Woodruff JM; Hinkin CH; Hoare J; Joska JA; Kallianpur KJ; Kuhn T; Lam HY; Law M; Lebrun-Frenay C; Levine AJ; Mondot L; Nakamoto BK; Navia BA; Pennec X; Porges EC; Shikuma CM; Thames AD; Valcour V; Vassallo M; Woods AJ; Thompson PM; Cohen RA; Paul R; Stein DJ; Jahanshad N; Group FTE-HW, Smaller limbic structures are associated with greater immunosuppression in over 1000 HIV-infected adults across five continents: Findings from the ENIGMA-HIV Working Group, http://dx.doi.org/10.1101/724583

Nir TM; Fouche J-P; Ananworanich J; Ances BM; Boban J; Brew BJ; Chaganti JR; Chang L; Ching CRK; Cysique LA; Ernst T; Faskowitz J; Gupta V; Harezlak J; Heaps-Woodruff JM; Hinkin CH; Hoare J; Joska JA; Kallianpur KJ; Kuhn T; Lam HY; Law M; Lebrun-Frenay C; Levine AJ; Mondot L; Nakamoto BK; Navia BA; Pennec X; Porges EC; Shikuma CM; Thames AD; Valcour V; Vassallo M; Woods AJ; Thompson PM; Cohen RA; Paul R; Stein DJ; Jahanshad N; Group ENIGMA-HIVW, Smaller Limbic Structures Are Associated with Immunosuppression and Viral Load in Over 1000 HIV-Infected Adults Across Five Continents: Findings from the ENIGMA-HIV Working Group, http://dx.doi.org/10.2139/ssrn.3444420

Malepathirana T; Senanayake D; Gautam V; Engel M; Balez R; Lovelace MD; Sundaram G; Heng B; Chow S; Marquis C; Guillemin G; Brew B; Jagadish C; Ooi L; Halgamuge S, Visualization of Incrementally Learned Projection Trajectories for Longitudinal Data, http://dx.doi.org/10.1101/2022.11.25.515889

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