By Professor Bruce James Brew

Journal articles

Croitoru-Lamoury J; Guillemin GJ; Dormont D; Brew BJ, 2003, 'Quinolinic acid up-regulates chemokine production and chemokinereceptor expression in astrocytes', Advances in Experimental Medicine and Biology, 527, pp. 37 - 45

Guillemin GJ; Croitoru J; Dormont J; Armati PJ; Brew BJ, 2003, 'Quinolinic acid upregulates chemokine production and chemokine receptor expression in astrocytes: implications for brain inflammation in AIDS', Glia, 41, pp. 371 - 381

Brew BJ, 2003, 'The peripheral nerve complications of human immunodeficiency virus (HIV) infection', Muscle and Nerve, 28, pp. 542 - 552

Guillemin GJ; Brew BJ, 2002, 'Implications of the kynurenine pathway and quinolinic acid in Alzheimer's disease', Redox Report, 7, pp. 199 - 206, http://dx.doi.org/10.1179/135100002125000550

Bain M; Brew B; Coltheart M, 2002, 'Progressive peripheral dysgraphia in early posterior cortical atrophy', NEUROBIOLOGY OF AGING, 23, pp. S39 - S40, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000177465300149&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Loy CT; Brew BJ, 2002, 'Treatment of opportunistic infections and lymphoma in the nervous system.', Journal of HIV therapy, 7, pp. 21 - 25

Smythe GA; Braga O; Brew BJ; Grant RS; Guillemin GJ; Kerr SJ; Walker DW, 2002, 'Concurrent quantification of quinolinic, picolinic and nicotinic acids using electron-capture negative-ion gas chromatography-mass spectrometry', Analytical Biochemistry, 301, pp. 21 - 26

Guillemin GJ; Brew BJ, 2002, 'Implications of the kynurenine pathway and quinolinic acid in Alzheimer`s disease', Redox Report, 7, pp. 1

Loy C; Brew BJ, 2002, 'Lymphona and opportunistic infections of the brain', Journal of Hiv Therapy, 7, pp. 21 - 25

Brew BJ, 2001, 'HTLV-I and HIV infections of the CNS in tropical areas [10]', Journal of Neurology Neurosurgery and Psychiatry, 70, pp. 138, http://dx.doi.org/10.1136/jnnp.70.1.138

Pemberton LA; Brew BJ, 2001, 'Cerebrospinal fluid S-100ß and its relationship with AIDS dementia complex.', Journal of Clinical Virology, pp. 249 - 253

Lanier ER; Sturge G; McClernon D; Brown S; Halman M; Sacktor N; McArthur J; Atkinson JH; Clifford D; Price R; Simpson D; Torres G; Catalan J; Marder K; Power C; Hall C; Romero C; Brew BJ, 2001, 'HIV-1 reverse transcriptase sequence in plasma and cerebrospinal fluid of patients with AIDS dementia complex treated with abacavir', AIDS, 15, pp. 747 - 751

Guillemin GJ; Kerr SJ; Pemberton LA; Smith DG; Smythe GA; Armati PJ; Brew BJ, 2001, 'IFN-b1b induces Kynurenine pathway metabolism in human macrophages:potential implications for multiple sclerosis treatment', Journal of Interferon and Cytokine Research, pp. 1097 - 1101

Guillemin GJ; Kerr SJ; Smythe GA; Smith DG; Kapoor V; Armati PJ; Croitoru J; Brew BJ, 2001, 'Kynurenine pathway metabolism in human astrocytes: a paradox for neuronal protection', Journal of Neurochemistry, pp. 842 - 853

Brew BJ, 2001, 'Markers of AIDS dementia complex: the role of cerebrospinal fluid assays', AIDS, 15, pp. 1883 - 1884

Smith DG; Guillemin GJ; Pemberton LA; Kerr SJ; Nath A; Smythe GA; Brew BJ, 2001, 'Quinolinic acid is produced by macrophages stimulated by platelet activating factor, NeF and Tat', Journal of Neurovirology, pp. 56 - 60

Smit T; Wang B; Ng T; Osborne R; Brew BJ; Saksena NK, 2001, 'Varied tropism of HIV-1 isolates derived from different regions of adult brain cortex discriminate between patients with and without AIDS Dementia Complex (ADC): evidence for neurotropic HIV variants.', Virology, pp. 509 - 526

Guillemin GJ; Smith DG; Kerr SJ; Smythe GA; Kapoor V; Armati P; Brew BJ, 2000, 'Characterisation of kynurenine pathway metabolism in human astrocytes and implications in neuropathogenesis', Redox Report, 5, pp. 108 - 111

Guillemin GJ; Smith DD; Kerr SJ; Smythe GA; Kapoor V; Armati P; Brew BJ, 2000, 'Characterisation of kynurenine pathway metabolism in human astrocytes and implications in neutopathogenesis', Redox Report, pp. 108 - 111

Brew BJ; Dore GJ, 2000, 'Decreasing incidence of CNS AIDS defining events associated with antiretroviral therapy (letter)', Neurology, pp. 1424 - 1424

Brew BJ, 2000, 'Does HHV-8 have a neuroprotective role on the development of HIV encephalopathy? (letter)', Neurology, pp. 459 - 460

Cunningham PH; Smith DD; Satchell C; Cooper DA; Brew BJ, 2000, 'Evidence for independent development of resistance to HIV-1 reverse transcriptase inhibitors in the cerebrospinal fluid.', AIDS, 14, pp. 1949 - 1954

Grulich AE; Dore GJ; Brew BJ, 2000, 'Human herpesvirus 8 and protection from AIDS dementia complex', Herpes, pp. 38 - 40

Dore GJ; Brew BJ, 2000, 'Response to Eberly et al., Kaposi¿s sarcoma and central nervous system disease: a real association or an artifact of the control group? (letter)', AIDS, 14, pp. 2631 - 2632

Brew BJ, 1999, 'AIDS dementia complex', Neurologic Clinics, 17, pp. 861 - 881

Dore GJ; Correll PK; Li Y; Kaldor JM; Cooper DA; Brew BJ, 1999, 'Changes to AIDS dementia complex in the era of highly active antiretroviral therapy', AIDS, 13, pp. 1249 - 1253

Brennan JD; Pell MF; Brew BJ, 1999, 'HIV-related primary cerebral lymphoma: the role of stereotactic biopsy', Journal of Clinical Neuroscience, pp. 217 - 220

Guillemin GJ; Kerr SJ; Smythe GA; Armati P; Brew BJ, 1999, 'Kynurenine pathway metabolism in human astrocytes', Advances in Experimental Medicine and Biology, pp. 125 - 131

Brew BJ; Gisslen M; Svennerholm B; Fuchs D; Hagberg L, 1998, 'Neurological efficacy of stavudine, zidovudine, and lamivudine (multiple letters) [2]', Lancet, 352, pp. 402 - 403, http://dx.doi.org/10.1016/s0140-6736(05)60498-9

Kerr SJ; Pemberton LA; Guillemin GJ; Smythe G; Brew BJ, 1998, 'Interferon-beta induces kynurenine pathway metabolism inhuman macrophages', NEUROLOGY, 50, pp. A34 - A34, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000073240900095&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Mcphee D; Greenway AL; Holloway G; Smith KR; Deacon N; Pemberton LA; Brew BJ, 1998, 'Anomalies in Nef expression within the central nervous system of HIV-1 positive individuals/AIDS patients with or without AIDS dementia complex', Journal of Neurovirology, pp. 291 - 300

Szeto ER; Freund J; Brew BJ; Loder A; Griffiths M, 1998, 'Cerebral perfusion scanning in treating AIDS dementia', Journal of Nuclear Medicine, pp. 298 - 302

Kerr SJ; Amarti PJ; Guilbaud G; Brew BJ, 1998, 'Chronic exposure of human neurons to quinolinic acid results in neuronal changes consistent with AIDS dementia complex', AIDS, 12, pp. 355 - 363

Brew BJ, 1998, 'Evaluation and management of intracranial mass lesions in AIDS - Report of the Quality Standards Subcommittee of the American Academy of Neurology', Neurology, pp. 1232 - 1233

Markus R; Brew BJ, 1998, 'HIV-1 peripheral neuropathy and combination antiretroviral therapy', Lancet, pp. 1906 - 1907

Dore GJ; Grulich AE; Law MG; Brew BJ; Kaldor JM, 1998, 'Kaposi¿s sarcoma and protection from AIDS dementia complex', AIDS, 12, pp. 2354 - 2355

Brew BJ, 1998, 'Neurological efficacy of stavudine, zidovudine, and lamivudine', Lancet, pp. 402 - 402

Bradley TP; Brew BJ, 1997, 'HIV type-1-related transient neurologic deficits [2] (multiple letters)', American Journal of Medicine, 103, pp. 250

Brew BJ, 1997, 'HIV type-1-related transient neurologic deficits - Reply', AMERICAN JOURNAL OF MEDICINE, 103, pp. 250 - 251, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1997XX32200012&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Johnson DW; Brew BK; Poronnik P; Cook DI; Field MJ; Gyory AZ; Pollock CA, 1997, 'Insulin-like growth factor I stimulates apical sodium/hydrogen exchange in human proximal tubule cells', AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 272, pp. F484 - F490, http://dx.doi.org/10.1152/ajprenal.1997.272.4.F484

Dunbar N; Pemberton L; Perdices M; Brew BJ, 1997, 'Clinical markers of the presence of dementia and neuropsychological impairment in hiv infection', Journal of Neuro-AIDS, 1, pp. 31 - 48, http://dx.doi.org/10.1300/J128v01n04_04

Dore GJ; Law MG; Brew BJ, 1997, 'Prospective analysis of seizures occurring in human immunodeficiency virus type-1 infection', Journal of Neuro-AIDS, 1, pp. 59 - 69, http://dx.doi.org/10.1300/J128v01n04_06

Kerr SJ; Armati PJ; Pemberton LA; Smythe G; Brew BJ, 1997, 'Kynurenine pathway inhibition with 6-chloro-D-tryptophan reduces neurotoxicity of HIV-1 infected macrophage supernatants', NEUROLOGY, 48, pp. 2008 - 2008, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1997XG87100226&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Dunbar N; Brew B, 1997, 'Neuropsychological Dysfunction in HIV Infection:A Review', Journal of neuro-AIDS, 1, pp. 73 - 102

Brew BJ, 1997, 'The cellular basis of central nervous HIV-1 infection and the AIDS dementia complex - Price,RW, Sidtis,JJ', VENEREOLOGY-THE INTERDISCIPLINARY INTERNATIONAL JOURNAL OF SEXUAL HEALTH, 10, pp. 126 - 126, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1997XV34400011&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Dick AD; Pell MF; Brew BJ; Foulcher E; Sedgwick JD, 1997, 'Direct ex vivo flow cytometric analysis of human microglial cell CD4 expression: examination of central nervous system biopsy specimens from HIV-seropositive patients and patients with other neurological disease', AIDS, 11, pp. 1699 - 1708

Cunningham AL; Naif H; Saksena N; Lynch G; Chang JW; Li S; Jozwiak R; Alali M; Wang B; Fear W; Sloane A; Pemberton LA; Brew BJ, 1997, 'HIV infection of macrophages and the pathogenesis of AIDS dementia complex: interaction of the host cell and viral genotype', Journal of Leukocyte Biology, pp. 117 - 125

Pemberton LA; Kerr SJ; Brew BJ, 1997, 'HIV-1 gp120 does not induce quinolinic acid production by macrophages', Journal of Neurovirology, pp. 86 - 87

Kerr SJ; Armati P; Pemberton LA; Smythe GA; Tattam B; Brew BJ, 1997, 'Kynurenine pathway inhibition reduces neurotoxicity of HIV-1-infected macrophages', Neurology, pp. 1671 - 1681

Brew BJ; Pemberton LA; Cunningham PH; Law MG, 1997, 'Levels of human imunodeficiency virus type RNA in cerebrospinal fluid correlae with AIDS dementia stage', Journal of Infectious Diseases, 175, pp. 963 - 966

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