By Professor Deborah Cromer

Journal articles

Akter J; Khoury DS; Aogo R; Lansink LIM; SheelaNair A; Thomas BS; Laohamonthonkul P; Pernold CPS; Dixon MWA; Soon MSF; Fogg LG; Engel JA; Elliott T; Sebina I; James KR; Cromer D; Davenport MP; Haque A, 2019, 'Plasmodium-specific antibodies block in vivo parasite growth without clearing infected red blood cells', Plos Pathogens, 15, pp. e1007599, http://dx.doi.org/10.1371/journal.ppat.1007599

Davenport MP; Khoury DS; Cromer D; Lewin SR; Kelleher AD; Kent SJ, 2019, 'Functional cure of HIV: the scale of the challenge', Nature Reviews Immunology, 19, pp. 45 - 54, http://dx.doi.org/10.1038/s41577-018-0085-4

Zaloumis SG; Cao P; Dini S; Davenport MP; Cromer D; Khoury DS; Fowkes FJI; McCaw JM; Simpson JA, 2018, 'In silico investigation of the decline in clinical efficacy of artemisinin combination therapies due to increasing artemisinin and partner drug resistance', Antimicrobial Agents and Chemotherapy, 62, pp. 10.1128/aac.01292 - 10.1128/aac.01218, http://dx.doi.org/10.1128/AAC.01292-18

Aogo RA; Khoury DS; Cromer D; Elliott T; Akter J; Fogg LG; Nair AS; Liligeto UN; Soon MSF; Thomas BS; Pernold CPS; Romanczuk AS; Laohamonthonkul P; Haque A; Davenport MP, 2018, 'Quantification of host-mediated parasite clearance during blood-stage Plasmodium infection and anti-malarial drug treatment in mice', International Journal for Parasitology, 48, pp. 903 - 913, http://dx.doi.org/10.1016/j.ijpara.2018.05.010

Khoury DS; Aogo R; Randriafanomezantsoa-Radohery G; McCaw JM; Simpson JA; McCarthy JS; Haque A; Cromer D; Davenport MP, 2018, 'Within-host modeling of blood-stage malaria', Immunological Reviews, 285, pp. 168 - 193, http://dx.doi.org/10.1111/imr.12697

Parsons MS; Cromer D; Davenport MP; Kent SJ, 2018, 'HIV Reactivation after Partial Protection by Neutralizing Antibodies', Trends in Immunology, 39, pp. 359 - 366, http://dx.doi.org/10.1016/j.it.2017.12.006

Pinkevych M; Fennessey CM; Cromer D; Tolstrup M; Søgaard OS; Rasmussen TA; Keele BF; Davenport MP, 2018, 'Estimating initial viral levels during simian immunodeficiency virus/human immunodeficiency virus reactivation from latency', Journal of Virology, 92, pp. 10.1128/jvi.01667 - 10.1128/jvi.01617, http://dx.doi.org/10.1128/JVI.01667-17

Khoury DS; Cromer D; Elliott T; Soon MSF; Thomas BS; James KR; Best SE; Aogo RA; Engel JA; Gartlan KH; Akter J; Sebina I; Haque A; Davenport MP, 2017, 'Characterising the effect of antimalarial drugs on the maturation and clearance of murine blood-stage Plasmodium parasites in vivo', International Journal for Parasitology, 47, pp. 913 - 922, http://dx.doi.org/10.1016/j.ijpara.2017.05.009

Cromer D; Pinkevych M; Rasmussen TA; Lewin SR; Kent SJ; Davenport MP, 2017, 'Modeling of antilatency treatment in HIV: What is the optimal duration of antiretroviral therapy-free HIV remission?', Journal of Virology, 91, pp. 10.1128/jvi.01395 - 10.1128/jvi.01317, http://dx.doi.org/10.1128/JVI.01395-17

Cao P; Klonis N; Zaloumis S; Khoury DS; Cromer D; Davenport MP; Tilley L; Simpson JA; McCaw JM, 2017, 'A mechanistic model quantifies artemisinin-induced parasite growth retardation in blood-stage Plasmodium falciparum infection', Journal of Theoretical Biology, 430, pp. 117 - 127, http://dx.doi.org/10.1016/j.jtbi.2017.07.017

Cromer D; van Hoek AJ; Newall AT; Pollard AJ; Jit M, 2017, 'Burden of paediatric respiratory syncytial virus disease and potential effect of different immunisation strategies: a modelling and cost-effectiveness analysis for England', Lancet Public Health, 2, pp. e367 - e374, http://dx.doi.org/10.1016/S2468-2667(17)30103-2

Khoury DS; Cromer D; Akter J; Sebina I; Elliott T; Thomas BS; Soon MSF; James KR; Best SE; Haque A; Davenport MP, 2017, 'Host-mediated impairment of parasite maturation during blood-stage Plasmodium infection', Proceedings of the National Academy of Sciences of the United States of America, 114, pp. 7701 - 7706, http://dx.doi.org/10.1073/pnas.1618939114

Griffin P; Pasay C; Elliott S; Sekuloski S; Sikulu M; Hugo L; Khoury D; Cromer D; Davenport M; Sattabongkot J; Ivinson K; Ockenhouse C; McCarthy J, 2016, 'Safety and Reproducibility of a Clinical Trial System Using Induced Blood Stage Plasmodium vivax Infection and Its Potential as a Model to Evaluate Malaria Transmission', Plos Neglected Tropical Diseases, 10, pp. e0005139, http://dx.doi.org/10.1371/journal.pntd.0005139

Khoury DS; Cromer D; Möhrle JJ; McCarthy JS; Davenport MP, 2016, 'Defining the effectiveness of antimalarial chemotherapy: Investigation of the lag in parasite clearance following drug administration', Journal of Infectious Diseases, 214, pp. 753 - 761, http://dx.doi.org/10.1093/infdis/jiw234

Pinkevych M; Cromer D; Tolstrup M; Grimm AJ; Cooper DA; Lewin SR; Søgaard OS; Rasmussen TA; Kent SJ; Kelleher AD; Davenport MP, 2016, 'Erratum: HIV Reactivation from Latency after Treatment Interruption Occurs on Average Every 5-8 Days-Implications for HIV Remission (PLoS Pathogens (2015) 11:7 (e1005000) DOI: 10.1371/journal.ppat.1005000)', Plos Pathogens, 12, pp. e1005745, http://dx.doi.org/10.1371/journal.ppat.1005745

Pinkevych M; Kent SJ; Tolstrup M; Lewin SR; Cooper DA; Søgaard OS; Rasmussen TA; Kelleher AD; Cromer D; Davenport MP, 2016, 'Modeling of Experimental Data Supports HIV Reactivation from Latency after Treatment Interruption on Average Once Every 5–8 Days', Plos Pathogens, 12, pp. e1005740, http://dx.doi.org/10.1371/journal.ppat.1005740

Adekunle AI; Cromer D; Davenport MP, 2016, 'Artemisinin-based treatments in pregnant women with malaria', New England Journal of Medicine, 375, pp. 283, http://dx.doi.org/10.1056/NEJMc1604709

Cromer D; Schlub TE; Smyth RP; Grimm AJ; Chopra A; Mallal S; Davenport MP; Mak J, 2016, 'HIV-1 mutation and recombination rates are different in macrophages and T-cells', Viruses, 8, pp. 118, http://dx.doi.org/10.3390/v8040118

Cromer D; Grimm AJ; Schlub TE; Mak J; Davenport MP, 2016, 'Estimating the in-vivo HIV template switching and recombination rate', AIDS, 30, pp. 185 - 192, http://dx.doi.org/10.1097/QAD.0000000000000936

Bilcke J; Chapman R; Atchison C; Cromer D; Johnson H; Willem L; Cox M; Edmunds WJ; Jit M, 2015, 'Quantifying Parameter and Structural Uncertainty of Dynamic Disease Transmission Models Using MCMC: An Application to Rotavirus Vaccination in England and Wales', Medical Decision Making, 35, pp. 633 - 647, http://dx.doi.org/10.1177/0272989X14566013

Pinkevych M; Cromer D; Tolstrup M; Grimm AJ; Cooper DA; Lewin SR; Søgaard OS; Rasmussen TA; Kent SJ; Kelleher AD; Davenport MP, 2015, 'HIV Reactivation from Latency after Treatment Interruption Occurs on Average Every 5-8 Days—Implications for HIV Remission', Plos Pathogens, 11, pp. e1005000, http://dx.doi.org/10.1371/journal.ppat.1005000

Khoury DS; Cromer D; Best SE; James KR; Sebina I; Haque A; Davenport MP, 2015, 'Reduced erythrocyte susceptibility and increased host clearance of young parasites slows Plasmodium growth in a murine model of severe malaria', Scientific Reports, 5, pp. 9412, http://dx.doi.org/10.1038/srep09412

Martyushev AP; Petravic J; Grimm AJ; Alinejad-Rokny H; Gooneratne SL; Reece JC; Cromer D; Kent SJ; Davenport MP, 2015, 'Epitope-specific CD8+ T cell kinetics rather than viral variability determine the timing of immune escape in simian immunodeficiency virus infection', Journal of Immunology, 194, pp. 4112 - 4121, http://dx.doi.org/10.4049/jimmunol.1400793

Waugh C; Cromer D; Grimm A; Chopra A; Mallal S; Davenport M; Mak J, 2015, 'A general method to eliminate laboratory induced recombinants during massive, parallel sequencing of cDNA library', Virology Journal, 12, pp. 55, http://dx.doi.org/10.1186/s12985-015-0280-x

Adekunle AI; Pinkevych M; McGready R; Luxemburger C; White LJ; Nosten F; Cromer D; Davenport MP, 2015, 'Modeling the Dynamics of Plasmodium vivax Infection and Hypnozoite Reactivation In Vivo', Plos Neglected Tropical Diseases, 9, pp. e0003595, http://dx.doi.org/10.1371/journal.pntd.0003595

Tey SK; Davenport MP; Hill GR; Kennedy GA; Durrant ST; Khanna R; Cromer D, 2015, 'Post transplant CMV-specific T-cell immune reconstitution in the absence of global T-cell immunity is associated with a high risk of subsequent virus reactivation', Bone Marrow Transplantation, 50, pp. 315 - 316, http://dx.doi.org/10.1038/bmt.2014.265

Fraser ST; Midwinter RG; Coupland LA; Kong S; Berger BS; Yeo JH; Andrade OC; Cromer D; Suarna C; Lam M; Maghzal GJ; Chong BH; Parish CR; Stocker R, 2015, 'Heme oxygenase-1 deficiency alters erythroblastic Island formation, steady-state erythropoiesis and red blood cell lifespan in mice', Haematologica, 100, pp. 601 - 610, http://dx.doi.org/10.3324/haematol.2014.116368

Yabas M; Coupland LA; Cromer D; Winterberg M; Teoh NC; D'rozario J; Kirk K; Bröer S; Parish CR; Enders A, 2014, 'Mice deficient in the putative phospholipid flippase Atp11c exhibit altered erythrocyte shape, anemia, and reduced erythrocyte life span', Journal of Biological Chemistry, 289, pp. 19531 - 19537, http://dx.doi.org/10.1074/jbc.C114.570267

Schlub TE; Grimm AJ; Smyth RP; Cromer D; Chopra A; Mallal S; Venturi V; Waugh C; Mak J; Davenport MP, 2014, 'Fifteen to twenty percent of HIV substitution mutations are associated with recombination', Journal of Virology, 88, pp. 3837 - 3849, http://dx.doi.org/10.1128/JVI.03136-13

Khoury DS; Cromer D; Best SE; James KR; Kim PS; Engwerda CR; Haque A; Davenport MP, 2014, 'Effect of mature blood-stage Plasmodium parasite sequestration on pathogen biomass in mathematical and in vivo models of malaria.', Infect Immun, 82, pp. 212 - 220, http://dx.doi.org/10.1128/IAI.00705-13

Smyth RP; Schlub TE; Grimm AJ; Waugh C; Ellenberg P; Chopra A; Mallal S; Cromer D; Mak J; Davenport MP, 2014, 'Identifying recombination hot spots in the HIV-1 genome.', J Virol, 88, pp. 2891 - 2902, http://dx.doi.org/10.1128/JVI.03014-13

Cromer D; van Hoek AJ; Jit M; Edmunds WJ; Fleming D; Miller E, 2014, 'The burden of influenza in England by age and clinical risk group: a statistical analysis to inform vaccine policy.', J Infect, 68, pp. 363 - 371, http://dx.doi.org/10.1016/j.jinf.2013.11.013

Lucy C; Yabas M; Cromer D; Winterberg M; Teoh N; Kirk K; Broer S; Parish C; Enders A, 2013, 'Anemia, Shortened Erythrocyte Lifespan and Stomatocytosis In a Flippase Mutant Mouse Strain', Blood, 122, pp. 2183 - 2183, http://dx.doi.org/10.1182/blood.v122.21.2183.2183

Tey SK; Kennedy GA; Cromer D; Davenport MP; Walker S; Jones LI; Crough T; Durrant ST; Morton JA; Butler JP; Misra AK; Hill GR; Khanna R, 2013, 'Clinical Assessment of Anti-Viral CD8+ T Cell Immune Monitoring Using QuantiFERON-CMV® Assay to Identify High Risk Allogeneic Hematopoietic Stem Cell Transplant Patients with CMV Infection Complications', Plos One, 8, pp. e74744, http://dx.doi.org/10.1371/journal.pone.0074744

Cromer D; Tey S-K; Khanna R; Davenport MP, 2013, 'Estimating cytomegalovirus growth rates by using only a single point.', J Virol, 87, pp. 3376 - 3381, http://dx.doi.org/10.1128/JVI.02821-12

Cromer D; Best SE; Engwerda C; Haque A; Davenport M, 2013, 'Where have all the parasites gone? Modelling early malaria parasite sequestration dynamics.', PLoS One, 8, pp. e55961, http://dx.doi.org/10.1371/journal.pone.0055961

Chan ML; Petravic J; Ortiz AM; Engram J; Paiardini M; Cromer D; Silvestri G; Davenport MP, 2010, 'Limited CD4+ T cell proliferation leads to preservation of CD4+ T cell counts in SIV-infected sooty mangabeys.', Proc Biol Sci, 277, pp. 3773 - 3781, http://dx.doi.org/10.1098/rspb.2010.0972

Jit M; Cromer D; Baguelin M; Stowe J; Andrews N; Miller E, 2010, 'The cost-effectiveness of vaccinating pregnant women against seasonal influenza in England and Wales.', Vaccine, 29, pp. 115 - 122, http://dx.doi.org/10.1016/j.vaccine.2010.08.078

Cromer D; Wolinsky SM; McLean AR, 2010, 'How fast could HIV change gene frequencies in the human population?', Proc Biol Sci, 277, pp. 1981 - 1989, http://dx.doi.org/10.1098/rspb.2009.2073

Coupland LA; Cromer D; Davenport MP; Parish CR, 2010, 'A novel fluorescent-based assay reveals that thrombopoietin signaling and Bcl-X(L) influence, respectively, platelet and erythrocyte lifespans.', Exp Hematol, 38, pp. 453 - 461.e1, http://dx.doi.org/10.1016/j.exphem.2010.03.003

Cromer D; Stark J; Davenport MP, 2009, 'Low red cell production may protect against severe anemia during a malaria infection--insights from modeling.', J Theor Biol, 257, pp. 533 - 542, http://dx.doi.org/10.1016/j.jtbi.2008.12.019

Cromer D; Christophides G; Stark J, 2009, 'Hidden variable analysis of transcription factor cooperativity from microarray time courses', IET Systems Biology, 4, pp. 131 - 144

Cromer D; Evans KJ; Schofield L; Davenport MP, 2006, 'Preferential invasion of reticulocytes during late-stage Plasmodium berghei infection accounts for reduced circulating reticulocyte levels.', Int J Parasitol, 36, pp. 1389 - 1397, http://dx.doi.org/10.1016/j.ijpara.2006.07.009

Conference Posters

Docken S; McCormick K; Pampena M; Pinkevych M; Viox E; Keele B; Paiardini M; Betts M; Bar K; Davenport M; Samer S; Cromer D; Schlub T, 2022, 'PP 2.3 – 00034 CD8+ T-Cell Sieving During SIV Reactivation from Latency', Vol. 8, pp. 100159 - 100159, http://dx.doi.org/10.1016/j.jve.2022.100159

Conference Abstracts

Lansink LIM; Engel JA; Lee HJ; Soon MSF; Williams CG; Aogo RA; Cromer D; Davenport MP; Khoury DS; Haque A, 2021, 'Exposure to host inflammation in vivo induces rapid transcriptomic change and impaired maturation in malaria parasites', in JOURNAL OF IMMUNOLOGY, AMER ASSOC IMMUNOLOGISTS, Vol. 206, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000713665801305&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Working Papers

Cele S; Jackson L; Khoury DS; Khan K; Moyo-Gwete T; Tegally H; San JE; Cromer D; Scheepers C; Amoako D; Karim F; Bernstein M; Lustig G; Archary D; Smith M; Ganga Y; Jule Z; Reedoy K; Hwa S-H; Giandhari J; Blackburn JM; Gosnell BI; Karim SSA; Hanekom W; NGS-SA ; Team C-K; von Gottberg A; Bhiman J; Lessells RJ; Moosa M-YS; Davenport MP; de Oliveira T; Moore PL; Sigal A, SARS-CoV-2 Omicron has extensive but incomplete escape of Pfizer BNT162b2 elicited neutralization and requires ACE2 for infection, Cold Spring Harbor Laboratory, http://dx.doi.org10.1101/2021.12.08.21267417

Preprints

Stadler E; Khan SR; Elias KM; Egilmezer E; Phetsouphanh C; Hastak P; Hewavisenti RV; Joshi RV; Turner T; Cromer D; Sasson SC; Davenport MP; Khoury DS, 2026, Immunogenicity and vaccine effectiveness of COVID-19 vaccines in people on immunosuppressive therapies, http://dx.doi.org/10.64898/2026.09.16.26363194

Aggarwal A; Stella A; Walker G; Akerman A; Milogiannakis V; Brilot F; Amatayakul-Chantler S; Roth N; Coppola G; Schofield P; Jackson J; Lenthall H; Mazigi O; Langley D; Lu Y; Forster C; McAllery S; Mathivanan V; Fitcher C; Hoppe AC; Munier CML; Jack H-M; Cromer D; Darley D; Matthews G; Christ D; Khoury D; Davenport M; Rawlinson W; Kelleher A; Turville S, 2022, SARS-CoV-2 Omicron: evasion of potent humoral responses and resistance to clinical immunotherapeutics relative to viral variants of concern, http://dx.doi.org/10.21203/rs.3.rs-1207364/v1

Cromer D; Steain M; Reynaldi A; Schlub TE; Wheatley AK; Juno JA; Kent SJ; Triccas JA; Khoury DS; Davenport MP, 2021, SARS-CoV-2 variants: levels of neutralisation required for protective immunity, http://dx.doi.org/10.1101/2021.08.11.21261876

Khoury DS; Cromer D; Reynaldi A; Schlub TE; Wheatley AK; Juno JA; Subbarao K; Kent SJ; Triccas JA; Davenport MP, 2021, What level of neutralising antibody protects from COVID-19?, http://dx.doi.org/10.1101/2021.03.09.21252641

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