By Professor Jeremy Somers Wilson

Journal articles

Mekapogu AR; Xu Z; Pothula S; Perera C; Pang T; Hosen SMZ; Damalanka V; Janetka J; Goldstein D; Pirola R; Wilson J; Apte M, 2023, 'HGF/c-Met pathway inhibition combined with chemotherapy increases cytotoxic T-cell infiltration and inhibits pancreatic tumour growth and metastasis', Cancer Letters, 568, http://dx.doi.org/10.1016/j.canlet.2023.216286

Hosen SMZ; Uddin MN; Xu Z; Buckley BJ; Perera C; Pang TCY; Mekapogu AR; Moni MA; Notta F; Gallinger S; Pirola R; Wilson J; Ranson M; Goldstein D; Apte M, 2022, 'Metastatic phenotype and immunosuppressive tumour microenvironment in pancreatic ductal adenocarcinoma: Key role of the urokinase plasminogen activator (PLAU)', Frontiers in Immunology, 13, http://dx.doi.org/10.3389/fimmu.2022.1060957

Channon LM; Tyma VM; Xu Z; Greening DW; Wilson JS; Perera CJ; Apte MV, 2022, 'Small extracellular vesicles (exosomes) and their cargo in pancreatic cancer: Key roles in the hallmarks of cancer', Biochimica et Biophysica Acta - Reviews on Cancer, 1877, pp. 188728, http://dx.doi.org/10.1016/j.bbcan.2022.188728

Perera CJ; Falasca M; Chari ST; Greenfield JR; Xu Z; Pirola RC; Wilson JS; Apte MV, 2021, 'Role of pancreatic stellate cell-derived exosomes in pancreatic cancer-related diabetes: A novel hypothesis', Cancers, 13, pp. 5224, http://dx.doi.org/10.3390/cancers13205224

Pang TCY; Xu Z; Mekapogu AR; Pothula S; Becker T; Corley S; Wilkins MR; Goldstein D; Pirola R; Wilson J; Apte M, 2021, 'Hgf/c-met inhibition as adjuvant therapy improves outcomes in an orthotopic mouse model of pancreatic cancer', Cancers, 13, pp. 2763, http://dx.doi.org/10.3390/cancers13112763

Pang TCY; Po JW; Becker TM; Goldstein D; Pirola RC; Wilson JS; Apte MV, 2021, 'Circulating tumour cells in pancreatic cancer: A systematic review and meta-analysis of clinicopathological implications', Pancreatology, 21, pp. 103 - 114, http://dx.doi.org/10.1016/j.pan.2020.11.022

Pothula SP; Xu Z; Goldstein D; Pirola RC; Wilson JS; Apte MV, 2020, 'Targeting hgf/c-met axis in pancreatic cancer', International Journal of Molecular Sciences, 21, pp. 1 - 18, http://dx.doi.org/10.3390/ijms21239170

Xu Z; Pothula S; Goldstein D; Pirola RC; Wilson JS; Apte MV, 2020, 'Reply letter to comments on: Targeting the HGF/c-MET pathway in advanced pancreatic cancer: a key element of treatment that limits primary tumour growth and eliminates metastasis', British Journal of Cancer, 123, pp. 1466, http://dx.doi.org/10.1038/s41416-020-1004-6

Pang TCY; Xu Z; Mekapogu AR; Pothula S; Becker TM; Goldstein D; Pirola RC; Wilson JS; Apte MV, 2020, 'An Orthotopic Resectional Mouse Model of Pancreatic Cancer', Journal of Visualized Experiments, http://dx.doi.org/10.3791/61726-v

Pang TCY; Xu Z; Mekapogu AR; Pothula S; Becker TM; Goldstein D; Pirola RC; Wilson JS; Apte MV, 2020, 'An orthotopic resectional mouse model of pancreatic cancer', Journal of Visualized Experiments, 2020, pp. 1 - 13, http://dx.doi.org/10.3791/61726

Xu Z; Pang TCY; Liu AC; Pothula SP; Mekapogu AR; Perera CJ; Murakami T; Goldstein D; Pirola RC; Wilson JS; Apte MV, 2020, 'Targeting the HGF/c-MET pathway in advanced pancreatic cancer: a key element of treatment that limits primary tumour growth and eliminates metastasis', British Journal of Cancer, 122, pp. 1486 - 1495, http://dx.doi.org/10.1038/s41416-020-0782-1

Pothula SP; Pirola RC; Wilson JS; Apte MV, 2020, 'Pancreatic stellate cells: Aiding and abetting pancreatic cancer progression', Pancreatology, 20, pp. 409 - 418, http://dx.doi.org/10.1016/j.pan.2020.01.003

Perera C; Xu Z; Mekapogu AR; Hosen SMZ; Pothula S; Greenfield J; Chari S; Goldstein D; Pirola R; Wilson J; Apte MV, 2020, '1133 PANCREATIC STELLATE CELL AND CANCER CELL DERIVED EXOSOMES IMPAIR BETA CELL FUNCTION: IMPLICATIONS FOR PANCREATIC CANCER RELATED DIABETES.', Gastroenterology, 158, pp. S - 221, http://dx.doi.org/10.1016/s0016-5085(20)31245-2

Zhu L; Dillon DL; Xu Z; Wightman CJ; Pirola R; Wilson J; Gukovskaya A; Apte MV; Mareninova OA, 2020, 'Mo1371 INFLAMMATORY RESPONSE IN EXPERIMENTAL PANCREATITIS INDUCED BY ALCOHOL AND CIGARETTE SMOKE IS MEDIATED THROUGH ROS-STAT3-P62 SIGNALING PATHWAY', Gastroenterology, 158, pp. S - 867, http://dx.doi.org/10.1016/s0016-5085(20)32848-1

Mekapogu AR; Pothula SP; Pirola RC; Wilson JS; Apte MV, 2019, 'Multifunctional role of pancreatic stellate cells in pancreatic cancer', Annals of Pancreatic Cancer, 2, http://dx.doi.org/10.21037/apc.2019.05.02

Neuzillet C; Tijeras-Raballand A; Ragulan C; Cros J; Patil Y; Martinet M; Erkan M; Kleeff J; Wilson J; Apte M; Tosolini M; Wilson AS; Delvecchio FR; Bousquet C; Paradis V; Hammel P; Sadanandam A; Kocher HM, 2019, 'Inter- and intra-tumoural heterogeneity in cancer-associated fibroblasts of human pancreatic ductal adenocarcinoma', Journal of Pathology, 248, pp. 51 - 65, http://dx.doi.org/10.1002/path.5224

Pang T; Xu Z; Pothula S; Yang MH; Becker T; Goldstein D; Heeschen C; Pirola R; Wilson J; Apte MV, 2018, '517 - World-First Identification of Circulating Pancreatic Stellate Cells in Metastatic Pancreatic Cancer', Gastroenterology, 154, pp. S - 114, http://dx.doi.org/10.1016/s0016-5085(18)30816-3

Lugea A; Gerloff A; Su HY; Xu Z; Go A; Hu C; French SW; Wilson JS; Apte MV; Waldron RT; Pandol SJ, 2017, 'The Combination of Alcohol and Cigarette Smoke Induces Endoplasmic Reticulum Stress and Cell Death in Pancreatic Acinar Cells', Gastroenterology, 153, pp. 1674 - 1686, http://dx.doi.org/10.1053/j.gastro.2017.08.036

Pang TCY; Wilson JS; Apte MV, 2017, 'Pancreatic stellate cells: What's new?', Current Opinion in Gastroenterology, 33, pp. 366 - 373, http://dx.doi.org/10.1097/MOG.0000000000000378

Nikfarjam M; Wilson JS; Smith RC; Australasian Pancreatic Club Pancreatic Enzyme Replacement Therapy Guidelines Working Group , 2017, 'Diagnosis and management of pancreatic exocrine insufficiency.', Med J Aust, http://dx.doi.org/10.5694/mja16.00851

Pang TCY; Xu Z; Pothula S; Becker T; Goldstein D; Pirola RC; Wilson JS; Apte MV, 2017, 'Circulating pancreatic stellate (stromal) cells in pancreatic cancer-a fertile area for novel research', Carcinogenesis, 38, pp. 588 - 591, http://dx.doi.org/10.1093/carcin/bgx030

Pothula SP; Xu Z; Goldstein D; Merrett N; Pirola RC; Wilson JS; Apte MV, 2017, 'Targeting the HGF/c-MET pathway: Stromal remodelling in pancreatic cancer', Oncotarget, 8, pp. 76722 - 76739, http://dx.doi.org/10.18632/oncotarget.20822

Apte MV; Wilson JS, 2016, 'Pancreatic cancer: A multipronged approach to pancreatic cancer treatment', Nature Reviews Gastroenterology and Hepatology, 13, pp. 385 - 387, http://dx.doi.org/10.1038/nrgastro.2016.75

Pinho AV; Apte MV; Wilson JS; Rooman I, 2016, 'Role of the microenvironment in chronic pancreatitis and pancreatic cancer', Cancer Forum, 40, pp. 11 - 15

Smith RC; Smith SF; Wilson J; Pearce C; Wray N; Vo R; Chen J; Ooi CY; Oliver M; Katz T; Turner R; Nikfarjam M; Rayner C; Horowitz M; Holtmann G; Talley N; Windsor J; Pirola R; Neale R, 2016, 'Summary and recommendations from the Australasian guidelines for the management of pancreatic exocrine insufficiency', Pancreatology, 16, pp. 164 - 180, http://dx.doi.org/10.1016/j.pan.2015.12.006

Pothula SP; Xu Z; Goldstein D; Biankin AV; Pirola RC; Wilson JS; Apte MV, 2016, 'Hepatocyte growth factor inhibition: A novel therapeutic approach in pancreatic cancer', British Journal of Cancer, 114, pp. 269 - 280, http://dx.doi.org/10.1038/bjc.2015.478

Pothula SP; Xu Z; Goldstein D; Pirola RC; Wilson JS; Apte MV, 2016, 'Key role of pancreatic stellate cells in pancreatic cancer', Cancer Letters, http://dx.doi.org/10.1016/j.canlet.2015.10.035

Wilson J; Pirola R; Apte M, 2016, 'Alcoholic pancreatitis in the modern era', Hamdan Medical Journal, 9, pp. 297 - 297, http://dx.doi.org/10.7707/hmj.689

Lee ATK; Xu Z; Pothula SP; Patel MB; Pirola RC; Wilson JS; Apte MV, 2015, 'Alcohol and Cigarette Smoke Components Activate Human Pancreatic Stellate Cells: Implications for the Progression of Chronic Pancreatitis', Alcoholism: Clinical and Experimental Research, 39, pp. 2123 - 2133, http://dx.doi.org/10.1111/acer.12882

Apte M; Pirola RC; Wilson JS, 2015, 'Pancreatic stellate cell: Physiologic role, role in fibrosis and cancer', Current Opinion in Gastroenterology, 31, pp. 416 - 423, http://dx.doi.org/10.1097/mog.0000000000000196

Apte MV; Xu Z; Pothula S; Goldstein D; Pirola RC; Wilson JS, 2015, 'Pancreatic cancer: The microenvironment needs attention too!', Pancreatology, 15, pp. S32 - S38, http://dx.doi.org/10.1016/j.pan.2015.02.013

Ali S; Suresh R; Banerjee S; Bao B; Xu Z; Wilson J; Philip PA; Apte M; Sarkar FH, 2015, 'Contribution of microRNAs in understanding the pancreatic tumor microenvironment involving cancer associated stellate and fibroblast cells.', American Journal of Cancer Research, 5, pp. 1251 - 1264

Sherman MH; Yu RT; Engle DD; Ding N; Atkins AR; Tiriac H; Collisson EA; Connor F; Van Dyke T; Kozlov S; Martin P; Tseng TW; Dawson DW; Donahue TR; Masamune A; Shimosegawa T; Apte MV; Wilson JS; Ng B; Lau SL; Gunton JE; Wahl GM; Hunter T; Drebin JA; O'Dwyer PJ; Liddle C; Tuveson DA; Downes M; Evans RM, 2014, 'Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy', Cell, 159, pp. 80 - 93, http://dx.doi.org/10.1016/j.cell.2014.08.007

Xu Z; Pothula SP; Wilson JS; Apte MV, 2014, 'Pancreatic cancer and its stroma: A conspiracy theory', World Journal of Gastroenterology, 20, pp. 11216 - 11229, http://dx.doi.org/10.3748/wjg.v20.i32.11216

Maraví-Poma E; Patchen Dellinger E; Forsmark CE; Layer P; Lévy P; Shimosegawa T; Siriwardena AK; Uomo G; Whitcomb DC; Windsor JA; Petrov MS; Abu Hilal M; Ammori BJ; Bharwani N; Carter CR; James FE; Johnson CD; Mofidi R; Mole DJ; Morris-Stiff G; O’Reilly DA; Parks RW; Rahman SH; Shankar-Hari M; Singer MV; Siriwardena AK; Skipworth JR; Abu-Zidan FM; Acosta JM; Ocampo C; Oria A; Pellegrini D; Ainsworth AP; Lund H; Nojgaard C; Aizcorbe Garralda M; Albeniz Arbizu E; Bernal Monterde V; De Casasola GG; de-Madaria E; Farre Viladrich A; Laplaza Santos C; Lopez A; Lopez Camps V; Macaya Redin L; Macias Rodriguez MA; Perez-Mateo M; Poves Prim I; Regidor Sanz E; Repiso A; Rodrigo L; Sánchez-Izquierdo Riera JA; Serrablo A; Tellado JM; Velasco Guardado A; Zubia Olazcoaga F; Alagozlu H; Aygencel G; Basaranoglu M; Col C; Kantarcioglu M; Karakan T; Kaya E; Muftuoglu M; Sezgin O; Tireli M; Al’aref SJ; Alhajeri A; Ashley SW; Ayoub WA; Baillie J; Banks PA; Baron TH; Chari ST; Conwell DL; Dellinger EP; Fagenholz PJ; Fernandez-del Castillo C; Forsmark CE; Gardner TB; Gluk M; Gumbs AA; Horvath KD; Howard TJ; Munsell MA; Papachristou GI; Parekh D; Pitchumoni CS; Savides TJ; Tarnasky PR; Tenner S; Vege SS; Warshaw AL; Whitcomb DC; Wu BU; Zyromski NJ; Almeida JL; Ardengh JC; Correia MI, 2014, 'International Multidisciplinary Classification of Acute Pancreatitis Severity: The 2013 Spanish Edition', Medicina Intensiva, 38, pp. 211 - 217, http://dx.doi.org/10.1016/j.medin.2013.03.013

Sze KCP; Pirola RC; Apte MV; Wilson JS, 2014, 'Current options for the diagnosis of chronic pancreatitis', Expert Review of Molecular Diagnostics, 14, pp. 199 - 215, http://dx.doi.org/10.1586/14737159.2014.883277

Wilson JS; Pirola RC; Apte MV, 2014, 'Stars and stripes in pancreatic cancer: Role of stellate cells and stroma in cancer progression', Frontiers in Physiology, 5 FEB, http://dx.doi.org/10.3389/fphys.2014.00052

Patel MB; Pothula SP; Xu Z; Lee AK; Goldstein D; Pirola RC; Apte MV; Wilson JS, 2014, 'The role of the hepatocyte growth factor/c-MET pathway in pancreatic stellate cell-endothelial cell interactions: Anti-angiogenic implications in pancreatic cancer', Carcinogenesis, 35, http://dx.doi.org/10.1093/carcin/bgu122

Apte MV; Wilson JS, 2014, 'In memoriam: Max G. Bachem, MD, PhD, Dr.hc Professor for Clinical Chemistry, 1952–2014', Pancreatology, 14, pp. 231 - 232, http://dx.doi.org/10.1016/j.pan.2014.07.001

Dellinger EP; Forsmark CE; Layer P; Levy P; Maraví-Poma E; Petrov MS; Shimosegawa T; Siriwardena AK; Uomo G; Whitcomb DC; Windsor JA; Abu Hilal M; Abu-Zidan FM; Acosta JM; Ainsworth AP; Aizcorbe Garralda M; Alagozlu H; Al'aref SJ; Albeniz Arbizu E; Alhajeri A; Almeida IC; Almeida JL; Amano H; Ammori BJ; Andersson R; Andrén-Sandberg A; Ardengh JC; Arroyo-Sanchez AS; Arvanitakis M; Ashley SW; Aygencel G; Ayoub WA; Baillie J; Bala M; Ball CG; Baron TH; Barreto SG; Basaranoglu M; Beger HG; Bernal Monterde V; Bharwani N; Bhasin DK; Bong JJ; Botoi G; Bruennler T; Cairoli E; Carter CR; Cernea D; Chari ST; Charnley RM; Chooklin S; Cochior D; Col C; Conwell DL; Correia MI; Dambrauskas Z; Darvas K; De Campos T; De Casasola GG; De Waele JJ; Del Chiaro M; Delle Fave G; Dellinger EP; De-Madaria E; Di Sebastiano P; Diuzheva TG; Duarte-Rojo A; Fagenholz PJ; Farkas G; Farre Viladrich A; Fernandezdel Castillo C; Forsmark CE; Friess H; Frossard JL; Gandhi V; Gardner TB; Gloor B; Gluk M; Goltsov VR; Guevara-Campos J; Gumbs AA; Hackert T; Hauser G; Horvath KD; Howard TJ; Igarashi H; Ioannidis O; Jaber S; James FE; Jha RK; Juneja D; Kamisawa T; Kandasami P; Kantarcioglu M; Kapoor VK; Karakan T; Kaya E; Khaliq A; Kiriyama S; Kochhar R, 2013, 'Determinant-based classification of acute pancreatitis severity: International multidisciplinary classification of acute pancreatitis severity: The 2013 German Edition', Zeitschrift fur Gastroenterologie, 51, pp. 544 - 550, http://dx.doi.org/10.1055/s-0033-1335526

Apte MV; Wilson JS; Lugea A; Pandol SJ, 2013, 'A starring role for stellate cells in the pancreatic cancer microenvironment', Gastroenterology, 144, pp. 1210 - 1219, http://dx.doi.org/10.1053/j.gastro.2012.11.037

Wilson JS; Pavey DA; Pirola RM; Apte MV, 2013, 'Current approaches to acute and chronic pancreatitis', Medicine Today, 14, pp. 34 - 40, http://www.medicinetoday.com.au/system/files/pdf/MT2013-04-034-WILSON.pdf

Apte MV; Yang L; Phillips PA; Xu ZH; Kaplan W; Cowley MJ; Pirola R; Wilson JS, 2013, 'Extracellular Matrix Composition significantly influences pancreatic stellate cell (PSC) gene expression pattern: role of transgelin in PSC function', American Journal of Physiology - Gastrointestinal and Liver Physiology, http://dx.doi.org/10.1152/ajpgi.00016.2013

Xu Z; Shah S; Pirola RC; Wilson J; Apte MV, 2013, 'Su1788 Pancreatic Fibrosis in Alcohol-Fed LPS Challenged Mice Is Regulated by the TLR4 Receptor', Gastroenterology, 144, pp. S - 477, http://dx.doi.org/10.1016/s0016-5085(13)61765-5

Shafiei M; Depczynski B; Russell HD; Apte MV; Wilson JS; Descallar J, 2013, 'The impact of diabetes on acute pancreatitis', Pancreatology, 13, pp. e73 - e73, http://dx.doi.org/10.1016/j.pan.2012.12.309

Dellinger EP; Forsmark CE; Layer P; Lévy P; Maraví-Poma E; Petrov MS; Shimosegawa T; Siriwardena AK; Uomo G; Whitcomb DC; Windsor JA; Abu Hilal M; Abu-Zidan FM; Acosta JM; Ainsworth AP; Aizcorbe Garralda M; Alagozlu H; Al’aref SJ; Albeniz Arbizu E; Alhajeri A; Almeida IC; Almeida JL; Amano H; Ammori BJ; Andersson B; Andersson R; Andrén-Sandberg A; Ardengh JC; Arroyo-Sanchez AS; Arvanitakis M; Ashley SW; Aygencel G; Ayoub WA; Baillie J; Bala M; Ball CG; Baron TH; Barreto SG; Basaranoglu M; Beger HG; Bernal Monterde V; Bharwani N; Bhasin DK; Bong JJ; Botoi G; Bruennler T; Cairoli E; Carter CR; Cernea D; Chari ST; Charnley RM; Chooklin S; Cochior D; Col C; Conwell DL; Correia MI; Dambrauskas Z; Darvas K; De Campos T; De Casasola GG; De Waele JJ; Del Chiaro M; Delle Fave G; De-Madaria E; Di Sebastiano P; Diuzheva TG; Duarte-Rojo A; Fagenholz PJ; Farkas G; Farre Viladrich A; Fernandez-Del Castillo C; Friess H; Frossard JL; Gandhi V; Gardner TB; Gloor B; Gluk M; Goltsov VR; Guevara-Campos J; Gumbs AA; Hackert T; Hauser G; Horvath KD; Howard TJ; Igarashi H; Ioannidis O; Jaber S; James FE; Jha RK; Juneja D; Kamisawa T; Kandasami P; Kantarcioglu M; Kapoor VK; Karakan T; Kaya E; Khaliq A; Kiriyama S; Kochhar R; Konstantinou GN, 2012, 'Determinant-based classification of acute pancreatitis severity: An international multidisciplinary consultation', Annals of Surgery, 256, pp. 875 - 880, http://dx.doi.org/10.1097/SLA.0b013e318256f778

Apte M; Xu Z; Wilson J, 2012, 'Battle-scarred pancreas: Role of pancreatic stellate cells', Pancreatology, 12, pp. e4 - e4, http://dx.doi.org/10.1016/j.pan.2012.07.008

Apte MV; Wilson JS, 2012, 'Dangerous liaisons: Pancreatic stellate cells and pancreatic cancer cells', Journal of Gastroenterology and Hepatology (JGH), 27, pp. 69 - 74, http://dx.doi.org/10.1111/j.1440-1746.2011.07000.x

Apte MV; Pirola R; Wilson JS, 2012, 'Pancreatic stellate cells: A starring role in normal and diseased pancreas', Frontiers in Physiology, 3, pp. Art. No. 344, http://dx.doi.org/10.3389/fphys.2012.00344

Erkan M; Adler G; Apte MV; Bachem MG; Buchholz M; Detlefsen S; Esposito I; Friess H; Gress TM; Habisch HJ; Hwang RN; Jaster R; Kleeff JH; Kloppel G; Kordes C; Logsdon CD; Masamune A; Michalski CW; Oh J; Pinzani M; Reiser-erkan C; Tsukamoto H; Wilson JS, 2012, 'StellaTUM: current consensus and discussion on pancreatic stellate cell research', Gut, 61, pp. 172 - 178, http://dx.doi.org/10.1136/gutjnl-2011-301220

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