By Professor Joseph Powell

Journal articles

Holton E; Muskovic W; Powell JE, 2024, 'Deciphering cancer cell state plasticity with single-cell genomics and artificial intelligence', Genome Medicine, 16, http://dx.doi.org/10.1186/s13073-024-01309-4

Neavin D; Senabouth A; Arora H; Lee JTH; Ripoll-Cladellas A; Franke L; Prabhakar S; Ye CJ; McCarthy DJ; Melé M; Hemberg M; Powell JE, 2024, 'Demuxafy: improvement in droplet assignment by integrating multiple single-cell demultiplexing and doublet detection methods', Genome Biology, 25, http://dx.doi.org/10.1186/s13059-024-03224-8

Greatbatch CJ; Lu Q; Hung S; Tran SN; Wing K; Liang H; Han X; Zhou T; Siggs OM; Mackey DA; Liu GS; Cook AL; Powell JE; Craig JE; MacGregor S; Hewitt AW, 2024, 'Deep Learning-Based Identification of Intraocular Pressure-Associated Genes Influencing Trabecular Meshwork Cell Morphology', Ophthalmology Science, 4, http://dx.doi.org/10.1016/j.xops.2024.100504

Zhou Z; Du J; Wang J; Liu L; Gordon MG; Ye CJ; Powell JE; Li MJ; Rao S, 2024, 'SingleQ: a comprehensive database of single-cell expression quantitative trait loci (sc-eQTLs) cross human tissues', Database, 2024, http://dx.doi.org/10.1093/database/baae010

Neavin DR; Steinmann AM; Farbehi N; Chiu HS; Daniszewski MS; Arora H; Bermudez Y; Moutinho C; Chan CL; Bax M; Tyebally M; Gnanasambandapillai V; Lam CE; Nguyen U; Hernández D; Lidgerwood GE; Graham RM; Hewitt AW; Pébay A; Palpant NJ; Powell JE, 2023, 'A village in a dish model system for population-scale hiPSC studies', Nature Communications, 14, http://dx.doi.org/10.1038/s41467-023-38704-1

Kang JB; Shen AZ; Gurajala S; Nathan A; Rumker L; Aguiar VRC; Valencia C; Lagattuta KA; Zhang F; Jonsson AH; Yazar S; Alquicira-Hernandez J; Khalili H; Ananthakrishnan AN; Jagadeesh K; Dey K; Albrecht J; Apruzzese W; Banda N; Barnas JL; Bathon JM; Ben-Artzi A; Boyce BF; Boyle DL; Bridges SL; Bykerk VP; Campbell D; Carr HL; Ceponis A; Chicoine A; Cordle A; Curtis M; Deane KD; DiCarlo E; Dunn P; Filer A; Firestein GS; Forbess L; Geraldino-Pardilla L; Goodman SM; Gravallese EM; Gregersen PK; Guthridge JM; Holers VM; Horowitz D; Hughes LB; Ishigaki K; Ivashkiv LB; James JA; Keras G; Korsunsky I; Lakhanpal A; Lederer JA; Lewis M; Li ZJ; Li Y; Liao KP; Mandelin AM; Mantel I; Marks KE; Maybury M; McDavid A; McGeachy MJ; Mears J; Meednu N; Millard N; Moreland LW; Nayar S; Nerviani A; Orange DE; Perlman H; Pitzalis C; Rangel-Moreno J; Raza K; Reshef Y; Ritchlin C; Rivellese F; Robinson WH; Sahbudin I; Singaraju A; Seifert JA; Slowikowski K; Smith MH; Tabechian D; Scheel-Toellner D; Utz PJ; Watts GFM; Wei K; Weinand K; Weisenfeld D; Weisman MH; Wyse A; Xiao Q; Zhu Z; Daly MJ; Xavier RJ; Donlin LT; Anolik JH; Powell JE; Rao DA, 2023, 'Mapping the dynamic genetic regulatory architecture of HLA genes at single-cell resolution', Nature Genetics, 55, pp. 2255 - 2268, http://dx.doi.org/10.1038/s41588-023-01586-6

Dai Q; Zhou G; Zhao H; Võsa U; Franke L; Battle A; Teumer A; Lehtimäki T; Raitakari OT; Esko T; Agbessi M; Ahsan H; Alves I; Andiappan AK; Arindrarto W; Awadalla P; Beutner F; Jan Bonder M; Boomsma DI; Christiansen MW; Claringbould A; Deelen P; Favé MJ; Frayling T; Gharib SA; Gibson G; Heijmans BT; Hemani G; Jansen R; Kähönen M; Kalnapenkis A; Kasela S; Kettunen J; Kim Y; Kirsten H; Kovacs P; Krohn K; Kronberg J; Kukushkina V; Kutalik Z; Lee B; Loeffler M; Marigorta UM; Mei H; Milani L; Montgomery GW; Müller-Nurasyid M; Nauck M; Nivard MG; Penninx B; Perola M; Pervjakova N; Pierce BL; Powell J; Prokisch H; Psaty BM; Ripatti S; Rotzschke O; Rüeger S; Saha A; Scholz M; Schramm K; Seppälä I; Slagboom EP; Stehouwer CDA; Stumvoll M; Sullivan P; ‘t Hoen PAC; Thiery J; Tong L; Tönjes A; van Dongen J; van Iterson M; van Meurs J; Veldink JH; Verlouw J; Visscher PM; Völker U; Westra HJ; Wijmenga C; Yaghootka H; Yang J; Zeng B; Zhang F; Epstein MP; Yang J, 2023, 'OTTERS: a powerful TWAS framework leveraging summary-level reference data', Nature Communications, 14, http://dx.doi.org/10.1038/s41467-023-36862-w

Xue A; Yazar S; Neavin D; Powell JE, 2023, 'Pitfalls and opportunities for applying latent variables in single-cell eQTL analyses', Genome Biology, 24, http://dx.doi.org/10.1186/s13059-023-02873-5

Sarrafha L; Neavin DR; Parfitt GM; Kruglikov IA; Whitney K; Reyes R; Coccia E; Kareva T; Goldman C; Tipon R; Croft G; Crary JF; Powell JE; Blanchard J; Ahfeldt T, 2023, 'Novel human pluripotent stem cell-derived hypothalamus organoids demonstrate cellular diversity', iScience, 26, http://dx.doi.org/10.1016/j.isci.2023.107525

Cuomo ASE; Nathan A; Raychaudhuri S; MacArthur DG; Powell JE, 2023, 'Single-cell genomics meets human genetics', Nature Reviews Genetics, 24, pp. 535 - 549, http://dx.doi.org/10.1038/s41576-023-00599-5

Lim J; Chin V; Fairfax K; Moutinho C; Suan D; Ji H; Powell JE, 2023, 'Transitioning single-cell genomics into the clinic', Nature Reviews Genetics, 24, pp. 573 - 584, http://dx.doi.org/10.1038/s41576-023-00613-w

Sikkema L; Ramírez-Suástegui C; Strobl DC; Gillett TE; Zappia L; Madissoon E; Markov NS; Zaragosi LE; Ji Y; Ansari M; Arguel MJ; Apperloo L; Banchero M; Bécavin C; Berg M; Chichelnitskiy E; Chung MI; Collin A; Gay ACA; Gote-Schniering J; Hooshiar Kashani B; Inecik K; Jain M; Kapellos TS; Kole TM; Leroy S; Mayr CH; Oliver AJ; von Papen M; Peter L; Taylor CJ; Walzthoeni T; Xu C; Bui LT; De Donno C; Dony L; Faiz A; Guo M; Gutierrez AJ; Heumos L; Huang N; Ibarra IL; Jackson ND; Kadur Lakshminarasimha Murthy P; Lotfollahi M; Tabib T; Talavera-López C; Travaglini KJ; Wilbrey-Clark A; Worlock KB; Yoshida M; Chen Y; Hagood JS; Agami A; Horvath P; Lundeberg J; Marquette CH; Pryhuber G; Samakovlis C; Sun X; Ware LB; Zhang K; van den Berge M; Bossé Y; Desai TJ; Eickelberg O; Kaminski N; Krasnow MA; Lafyatis R; Nikolic MZ; Powell JE; Rajagopal J; Rojas M; Rozenblatt-Rosen O; Seibold MA; Sheppard D; Shepherd DP; Sin DD; Timens W; Tsankov AM; Whitsett J; Xu Y; Banovich NE; Barbry P; Duong TE; Falk CS; Meyer KB; Kropski JA; Pe’er D; Schiller HB; Tata PR; Schultze JL; Teichmann SA; Misharin AV; Nawijn MC; Luecken MD; Theis FJ, 2023, 'An integrated cell atlas of the lung in health and disease', Nature Medicine, 29, pp. 1563 - 1577, http://dx.doi.org/10.1038/s41591-023-02327-2

Grimm L; Mason E; Yu H; Dudczig S; Panara V; Chen T; Bower NI; Paterson S; Rondon Galeano M; Kobayashi S; Senabouth A; Lagendijk AK; Powell J; Smith KA; Okuda KS; Koltowska K; Hogan BM, 2023, 'Single-cell analysis of lymphatic endothelial cell fate specification and differentiation during zebrafish development', EMBO Journal, 42, http://dx.doi.org/10.15252/embj.2022112590

Ballinger ML; Pattnaik S; Mundra PA; Zaheed M; Rath E; Priestley P; Baber J; Ray-Coquard I; Isambert N; Causeret S; van der Graaf WTA; Puri A; Duffaud F; Le Cesne A; Seddon B; Chandrasekar C; Schiffman JD; Brohl AS; James PA; Kurtz JE; Penel N; Myklebost O; Meza-Zepeda LA; Pickett H; Kansara M; Waddell N; Kondrashova O; Pearson JV; Barbour AP; Li S; Nguyen TL; Fatkin D; Graham RM; Giannoulatou E; Green MJ; Kaplan W; Ravishankar S; Copty J; Powell JE; Cuppen E; van Eijk K; Veldink J; Ahn JH; Kim JE; Lor Randall R; Tucker K; Judson I; Sarin R; Ludwig T; Genin E; Deleuze JF; Haber M; Marshall G; Cairns MJ; Blay JY; Thomas DM, 2023, 'Heritable defects in telomere and mitotic function selectively predispose to sarcomas', Science, 379, pp. 253 - 260, http://dx.doi.org/10.1126/science.abj4784

Brown M; Greenwood E; Zeng B; Powell JE; Gibson G, 2023, 'Effect of all-but-one conditional analysis for eQTL isolation in peripheral blood', Genetics, 223, http://dx.doi.org/10.1093/genetics/iyac162

Khoo WH; Jackson K; Phetsouphanh C; Zaunders JJ; Alquicira-Hernandez J; Yazar S; Ruiz-Diaz S; Singh M; Dhenni R; Kyaw W; Tea F; Merheb V; Lee FXZ; Burrell R; Howard-Jones A; Koirala A; Zhou L; Yuksel A; Catchpoole DR; Lai CL; Vitagliano TL; Rouet R; Christ D; Tang B; West NP; George S; Gerrard J; Croucher PI; Kelleher AD; Goodnow CG; Sprent JD; Powell JE; Brilot F; Nanan R; Hsu PS; Deenick EK; Britton PN; Phan TG, 2023, 'Tracking the clonal dynamics of SARS-CoV-2-specific T cells in children and adults with mild/asymptomatic COVID-19', Clinical Immunology, 246, http://dx.doi.org/10.1016/j.clim.2022.109209

Wilson SB; Howden SE; Vanslambrouck JM; Dorison A; Alquicira-Hernandez J; Powell JE; Little MH, 2022, 'DevKidCC allows for robust classification and direct comparisons of kidney organoid datasets', Genome Medicine, 14, http://dx.doi.org/10.1186/s13073-022-01023-z

Senabouth A; Daniszewski M; Lidgerwood GE; Liang HH; Hernández D; Mirzaei M; Keenan SN; Zhang R; Han X; Neavin D; Rooney L; Lopez Sanchez MIG; Gulluyan L; Paulo JA; Clarke L; Kearns LS; Gnanasambandapillai V; Chan CL; Nguyen U; Steinmann AM; McCloy RA; Farbehi N; Gupta VK; Mackey DA; Bylsma G; Verma N; MacGregor S; Watt MJ; Guymer RH; Powell JE; Hewitt AW; Pébay A, 2022, 'Transcriptomic and proteomic retinal pigment epithelium signatures of age-related macular degeneration', Nature Communications, 13, http://dx.doi.org/10.1038/s41467-022-31707-4

Phipson B; Sim CB; Porrello ER; Hewitt AW; Powell J; Oshlack A, 2022, 'propeller: testing for differences in cell type proportions in single cell data', Bioinformatics, 38, pp. 4720 - 4726, http://dx.doi.org/10.1093/bioinformatics/btac582

Yazar S; Powell JE, 2022, 'Single-cell expression Quantitative Trait Loci: T-cell immunology teams up with statistical genetics', Immunology and Cell Biology, 100, pp. 588 - 590, http://dx.doi.org/10.1111/imcb.12577

Patel B; Kleeman SO; Neavin D; Powell J; Baskozos G; Ng M; Ahmed WUR; Bennett DL; Schmid AB; Furniss D; Wiberg A, 2022, 'Shared genetic susceptibility between trigger finger and carpal tunnel syndrome: a genome-wide association study', The Lancet Rheumatology, 4, pp. e556 - e565, http://dx.doi.org/10.1016/S2665-9913(22)00180-1

Daniszewski M; Senabouth A; Liang HH; Han X; Lidgerwood GE; Hernández D; Sivakumaran P; Clarke JE; Lim SY; Lees JG; Rooney L; Gulluyan L; Souzeau E; Graham SL; Chan CL; Nguyen U; Farbehi N; Gnanasambandapillai V; McCloy RA; Clarke L; Kearns LS; Mackey DA; Craig JE; MacGregor S; Powell JE; Pébay A; Hewitt AW, 2022, 'Retinal ganglion cell-specific genetic regulation in primary open-angle glaucoma', Cell Genomics, 2, http://dx.doi.org/10.1016/j.xgen.2022.100142

Yazar S; Alquicira-Hernandez J; Wing K; Senabouth A; Gordon MG; Andersen S; Lu Q; Rowson A; Taylor TRP; Clarke L; Maccora K; Chen C; Cook AL; Ye CJ; Fairfax KA; Hewitt AW; Powell JE, 2022, 'Single-cell eQTL mapping identifies cell type-specific genetic control of autoimmune disease', Science, 376, http://dx.doi.org/10.1126/science.abf3041

Zammit NW; McDowell J; Warren J; Muskovic W; Gamble J; Shi YC; Kaczorowski D; Chan CL; Powell J; Ormandy C; Brown D; Oakes SR; Grey ST, 2022, 'TNFAIP3 Reduction-of-Function Drives Female Infertility and CNS Inflammation', Frontiers in Immunology, 13, http://dx.doi.org/10.3389/fimmu.2022.811525

Talenti A; Powell J; Hemmink JD; Cook EAJ; Wragg D; Jayaraman S; Paxton E; Ezeasor C; Obishakin ET; Agusi ER; Tijjani A; Amanyire W; Muhanguzi D; Marshall K; Fisch A; Ferreira BR; Qasim A; Chaudhry U; Wiener P; Toye P; Morrison LJ; Connelley T; Prendergast JGD, 2022, 'A cattle graph genome incorporating global breed diversity.', Nat Commun, 13, pp. 910, http://dx.doi.org/10.1038/s41467-022-28605-0

Chin V; Arora H; Senabouth A; Hernandez JA; McCloy R; Simes J; Boyer M; Hogg P; Young J; Joshua A; Brown B; Watkins N; Powell J, 2022, 'EP16.03-041 Single Cell RNA Sequencing Reveals Phenotypic Predispositions to Developing Lung Cancer in Never-Smokers', Journal of Thoracic Oncology, 17, pp. S608 - S608, http://dx.doi.org/10.1016/j.jtho.2022.07.1102

Bui LT; Winters NI; Chung MI; Joseph C; Gutierrez AJ; Habermann AC; Adams TS; Schupp JC; Poli S; Peter LM; Taylor CJ; Blackburn JB; Richmond BW; Nicholson AG; Rassl D; Wallace WA; Rosas IO; Jenkins RG; Kaminski N; Kropski JA; Banovich NE; Misharin AV; Tsankov AM; Spira A; Barbry P; Brazma A; Samakovlis C; Shepherd DP; Rawlins EL; Theis FJ; Griffonnet J; Lee H; Schiller HB; Hofman P; Powell JE; Schultze JL; Whitsett J; Choi J; Lundeberg J; Ordovas-Montanes J; Rajagopal J; Meyer KB; Krasnow MA; Saeb‐Parsy K; Zhang K; Lafyatis R; Leroy S; Haniffa M; Nawijn MC; Nikolić MZ; van den Berge M; Kuhnemund M; Marquette CH; Von Papen M; Eickelberg O; Rosenblatt-Rosen O; Reyfman PA; Pe’er D; Horvath P; Tata PR; Regev A; Rojas M; Seibold MA; Shalek AK; Spence JR; Teichmann SA; Quake S; Duong TE; Biancalani T; Desai T; Sun X; Zaragosi LE, 2021, 'Chronic lung diseases are associated with gene expression programs favoring SARS-CoV-2 entry and severity', Nature Communications, 12, http://dx.doi.org/10.1038/s41467-021-24467-0

Wu SZ; Roden DL; Al-Eryani G; Bartonicek N; Harvey K; Cazet AS; Chan CL; Junankar S; Hui MN; Millar EA; Beretov J; Horvath L; Joshua AM; Stricker P; Wilmott JS; Quek C; Long GV; Scolyer RA; Yeung BZ; Segara D; Mak C; Warrier S; Powell JE; O’Toole S; Lim E; Swarbrick A, 2021, 'Cryopreservation of human cancers conserves tumour heterogeneity for single-cell multi-omics analysis', Genome Medicine, 13, http://dx.doi.org/10.1186/s13073-021-00885-z

Muskovic W; Powell JE, 2021, 'DropletQC: improved identification of empty droplets and damaged cells in single-cell RNA-seq data', Genome Biology, 22, http://dx.doi.org/10.1186/s13059-021-02547-0

Mills MC; Tropf FC; Brazel DM; van Zuydam N; Vaez A; Agbessi M; Ahsan H; Alves I; Andiappan AK; Arindrarto W; Awadalla P; Battle A; Beutner F; Jan Bonder M; Boomsma DI; Christiansen MW; Claringbould A; Deelen P; Esko T; Favé MJ; Franke L; Frayling T; Gharib SA; Gibson G; Heijmans BT; Hemani G; Jansen R; Kähönen M; Kalnapenkis A; Kasela S; Kettunen J; Kim Y; Kirsten H; Kovacs P; Krohn K; Kronberg J; Kukushkina V; Kutalik Z; Lee B; Lehtimäki T; Loeffler M; Marigorta UM; Mei H; Milani L; Montgomery GW; Müller-Nurasyid M; Nauck M; Nivard MG; Penninx BWJH; Perola M; Pervjakova N; Pierce BL; Powell J; Prokisch H; Psaty BM; Raitakari OT; Ripatti S; Rotzschke O; Rüeger S; Saha A; Scholz M; Schramm K; Seppälä I; Slagboom EP; Stehouwer CDA; Stumvoll M; Sullivan P; ‘t Hoen PAC; Teumer A; Thiery J; Tong L; Tönjes A; van Dongen J; van Iterson M; van Meurs J; Veldink JH; Verlouw J; Visscher PM; Völker U; Võsa U; Westra HJ; Wijmenga C; Yaghootkar H; Yang J; Zeng B; Zhang F; Akimova ET; Bergmann S; Boardman JD; Brumat M; Franke L; Cesarini D; Chasman DI; Chavarro JE; Cocca M; Concas MP; Davey-Smith G; Davies G; Deary IJ; Wijmenga C, 2021, 'Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour', Nature Human Behaviour, 5, pp. 1717 - 1730, http://dx.doi.org/10.1038/s41562-021-01135-3

Shen S; Sun Y; Matsumoto M; Shim WJ; Sinniah E; Wilson SB; Werner T; Wu Z; Bradford ST; Hudson J; Little MH; Powell J; Nguyen Q; Palpant NJ, 2021, 'Integrating single-cell genomics pipelines to discover mechanisms of stem cell differentiation', Trends in Molecular Medicine, 27, pp. 1135 - 1158, http://dx.doi.org/10.1016/j.molmed.2021.09.006

Neavin D; Nguyen Q; Daniszewski MS; Liang HH; Chiu HS; Wee YK; Senabouth A; Lukowski SW; Crombie DE; Lidgerwood GE; Hernández D; Vickers JC; Cook AL; Palpant NJ; Pébay A; Hewitt AW; Powell JE, 2021, 'Single cell eQTL analysis identifies cell type-specific genetic control of gene expression in fibroblasts and reprogrammed induced pluripotent stem cells', Genome Biology, 22, http://dx.doi.org/10.1186/s13059-021-02293-3

Tuong ZK; Lukowski SW; Nguyen QH; Chandra J; Zhou C; Gillinder K; Bashaw AA; Ferdinand JR; Stewart BJ; Teoh SM; Hanson SJ; Devitt K; Clatworthy MR; Powell JE; Frazer IH, 2021, 'A model of impaired Langerhans cell maturation associated with HPV induced epithelial hyperplasia', iScience, 24, http://dx.doi.org/10.1016/j.isci.2021.103326

Currant H; Hysi P; Fitzgerald TW; Gharahkhani P; Bonnemaijer PWM; Senabouth A; Hewitt AW; Atan D; Aung T; Charng J; Choquet H; Craig J; Khaw PT; Klaver CCW; Kubo M; Ong JS; Pasquale LR; Reisman CA; Daniszewski M; Powell JE; Pébay A; Simcoe MJ; Thiadens AAHJ; van Duijn CM; Yazar S; Jorgenson E; MacGregor S; Hammond CJ; Mackey DA; Wiggs JL; Foster PJ; Patel PJ; Birney E; Khawaja AP, 2021, 'Erratum: Genetic variation affects morphological retinal phenotypes extracted from UK Biobank optical coherence tomography images (PLoS Genet (2021) 17:5 (e1009497) DOI: 10.1371/journal.pgen.1009497)', PLoS Genetics, 17, http://dx.doi.org/10.1371/journal.pgen.1009858

Nieto P; Elosua-Bayes M; Trincado JL; Marchese D; Massoni-Badosa R; Salvany M; Henriques A; Nieto J; Aguilar-Fernández S; Mereu E; Moutinho C; Ruiz S; Lorden P; Chin VT; Kaczorowski D; Chan CL; Gallagher R; Chou A; Planas-Rigol E; Rubio-Perez C; Gut I; Piulats JM; Seoane J; Powell JE; Batlle E; Heyn H, 2021, 'A single-cell tumor immune atlas for precision oncology', Genome Research, 31, pp. 1913 - 1926, http://dx.doi.org/10.1101/gr.273300.120

Du Q; Smith GC; Luu PL; Ferguson JM; Armstrong NJ; Caldon CE; Campbell EM; Nair SS; Zotenko E; Gould CM; Buckley M; Chia KM; Portman N; Lim E; Kaczorowski D; Chan CL; Barton K; Deveson IW; Smith MA; Powell JE; Skvortsova K; Stirzaker C; Achinger-Kawecka J; Clark SJ, 2021, 'DNA methylation is required to maintain both DNA replication timing precision and 3D genome organization integrity', Cell Reports, 36, http://dx.doi.org/10.1016/j.celrep.2021.109722

Wu SZ; Al-Eryani G; Roden DL; Junankar S; Harvey K; Andersson A; Thennavan A; Wang C; Torpy JR; Bartonicek N; Wang T; Larsson L; Kaczorowski D; Weisenfeld NI; Uytingco CR; Chew JG; Bent ZW; Chan CL; Gnanasambandapillai V; Dutertre CA; Gluch L; Hui MN; Beith J; Parker A; Robbins E; Segara D; Cooper C; Mak C; Chan B; Warrier S; Ginhoux F; Millar E; Powell JE; Williams SR; Liu XS; O’Toole S; Lim E; Lundeberg J; Perou CM; Swarbrick A, 2021, 'A single-cell and spatially resolved atlas of human breast cancers', Nature Genetics, 53, pp. 1334 - 1347, http://dx.doi.org/10.1038/s41588-021-00911-1

Võsa U; Claringbould A; Westra HJ; Bonder MJ; Deelen P; Zeng B; Kirsten H; Saha A; Kreuzhuber R; Yazar S; Brugge H; Oelen R; de Vries DH; van der Wijst MGP; Kasela S; Pervjakova N; Alves I; Favé MJ; Agbessi M; Christiansen MW; Jansen R; Seppälä I; Tong L; Teumer A; Schramm K; Hemani G; Verlouw J; Yaghootkar H; Sönmez Flitman R; Brown A; Kukushkina V; Kalnapenkis A; Rüeger S; Porcu E; Kronberg J; Kettunen J; Lee B; Zhang F; Qi T; Hernandez JA; Arindrarto W; Beutner F; ’t Hoen PAC; van Meurs J; van Dongen J; van Iterson M; Swertz MA; Jan Bonder M; Dmitrieva J; Elansary M; Fairfax BP; Georges M; Heijmans BT; Hewitt AW; Kähönen M; Kim Y; Knight JC; Kovacs P; Krohn K; Li S; Loeffler M; Marigorta UM; Mei H; Momozawa Y; Müller-Nurasyid M; Nauck M; Nivard MG; Penninx BWJH; Pritchard JK; Raitakari OT; Rotzschke O; Slagboom EP; Stehouwer CDA; Stumvoll M; Sullivan P; Thiery J; Tönjes A; van Dongen J; Veldink JH; Völker U; Warmerdam R; Wijmenga C; Swertz M; Andiappan A; Montgomery GW; Ripatti S; Perola M; Kutalik Z; Dermitzakis E; Bergmann S; Frayling T; Prokisch H; Ahsan H; Pierce BL; Lehtimäki T; Boomsma DI; Psaty BM, 2021, 'Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression', Nature Genetics, 53, pp. 1300 - 1310, http://dx.doi.org/10.1038/s41588-021-00913-z

Cohen J; Blumenthal A; Cuellar-Partida G; Evans DM; Finfer S; Li Q; Ljungberg J; Myburgh J; Peach E; Powell J; Rajbhandari D; Rhodes A; Senabouth A; Venkatesh B, 2021, 'The relationship between adrenocortical candidate gene expression and clinical response to hydrocortisone in patients with septic shock', Intensive Care Medicine, 47, pp. 974 - 983, http://dx.doi.org/10.1007/s00134-021-06464-5

Alquicira-Hernandez J; Powell JE, 2021, 'Nebulosa recovers single-cell gene expression signals by kernel density estimation', Bioinformatics, 37, pp. 2485 - 2487, http://dx.doi.org/10.1093/bioinformatics/btab003

Hemani G; Powell JE; Wang H; Shakhbazov K; Westra HJ; Esko T; Henders AK; McRae AF; Martin NG; Metspalu A; Franke L; Montgomery GW; Goddard ME; Gibson G; Yang J; Visscher PM, 2021, 'Phantom epistasis between unlinked loci', Nature, 596, pp. E1 - E3, http://dx.doi.org/10.1038/s41586-021-03765-z

Hemani G; Shakhbazov K; Westra HJ; Esko T; Henders AK; McRae AF; Yang J; Gibson G; Martin NG; Metspalu A; Franke L; Montgomery GW; Visscher PM; Powell JE, 2021, 'Retraction Note: Detection and replication of epistasis influencing transcription in humans (Nature, (2014), 508, 7495, (249-253), 10.1038/nature13005)', Nature, 596, pp. 306, http://dx.doi.org/10.1038/s41586-021-03766-y

Thompson M; Matsumoto M; Ma T; Senabouth A; Palpant NJ; Powell JE; Nguyen Q, 2021, 'scGPS: Determining Cell States and Global Fate Potential of Subpopulations', Frontiers in Genetics, 12, http://dx.doi.org/10.3389/fgene.2021.666771

Currant H; Hysi P; Fitzgerald TW; Gharahkhani P; Bonnemaijer PWM; Senabouth A; Hewitt AW; Atan D; Aung T; Charng J; Choquet H; Craig J; Khaw PT; Klaver CCW; Kubo M; Ong JS; Pasquale LR; Reisman CA; Daniszewski M; Powell JE; Pébay A; Simcoe MJ; Thiadens AAHJ; van Duijn CM; Yazar S; Jorgenson E; MacGregor S; Hammond CJ; Mackey DA; Wiggs JL; Foster PJ; Patel PJ; Birney E; Khawaja AP, 2021, 'Genetic variation affects morphological retinal phenotypes extracted from UK Biobank optical coherence tomography images', PLoS Genetics, 17, http://dx.doi.org/10.1371/journal.pgen.1009497

Lidgerwood GE; Senabouth A; Smith-Anttila CJA; Gnanasambandapillai V; Kaczorowski DC; Amann-Zalcenstein D; Fletcher EL; Naik SH; Hewitt AW; Powell JE; Pébay A, 2021, 'Transcriptomic Profiling of Human Pluripotent Stem Cell-derived Retinal Pigment Epithelium over Time', Genomics, Proteomics and Bioinformatics, 19, pp. 223 - 242, http://dx.doi.org/10.1016/j.gpb.2020.08.002

Muus C; Luecken MD; Eraslan G; Sikkema L; Waghray A; Heimberg G; Kobayashi Y; Vaishnav ED; Subramanian A; Smillie C; Jagadeesh KA; Duong ET; Fiskin E; Triglia ET; Ansari M; Cai P; Lin B; Buchanan J; Chen S; Shu J; Haber AL; Chung H; Montoro DT; Adams T; Aliee H; Allon SJ; Andrusivova Z; Angelidis I; Ashenberg O; Bassler K; Bécavin C; Benhar I; Bergenstråhle J; Bergenstråhle L; Bolt L; Braun E; Bui LT; Callori S; Chaffin M; Chichelnitskiy E; Chiou J; Conlon TM; Cuoco MS; Cuomo ASE; Deprez M; Duclos G; Fine D; Fischer DS; Ghazanfar S; Gillich A; Giotti B; Gould J; Guo M; Gutierrez AJ; Habermann AC; Harvey T; He P; Hou X; Hu L; Hu Y; Jaiswal A; Ji L; Jiang P; Kapellos TS; Kuo CS; Larsson L; Leney-Greene MA; Lim K; Litviňuková M; Ludwig LS; Lukassen S; Luo W; Maatz H; Madissoon E; Mamanova L; Manakongtreecheep K; Leroy S; Mayr CH; Mbano IM; McAdams AM; Nabhan AN; Nyquist SK; Penland L; Poirion OB; Poli S; Qi CC; Queen R; Reichart D; Rosas I; Schupp JC; Shea CV; Shi X; Sinha R; Sit RV; Slowikowski K; Slyper M; Smith NP; Sountoulidis A; Strunz M; Sullivan TB; Powell J, 2021, 'Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics', Nature Medicine, 27, pp. 546 - 559, http://dx.doi.org/10.1038/s41591-020-01227-z

Alquicira-Hernandez J; Powell JE; Phan TG, 2021, 'No evidence that plasmablasts transdifferentiate into developing neutrophils in severe COVID-19 disease', Clinical and Translational Immunology, 10, http://dx.doi.org/10.1002/cti2.1308

Sinclair KA; Yerkovich ST; Hopkins PMA; Fieuw AM; Ford P; Powell JE; O'Sullivan B; Chambers DC, 2021, 'The autotaxin-lysophosphatidic acid pathway mediates mesenchymal cell recruitment and fibrotic contraction in lung transplant fibrosis', Journal of Heart and Lung Transplantation, 40, pp. 12 - 23, http://dx.doi.org/10.1016/j.healun.2020.10.005

Chin V; Stone E; Havryk A; Plit M; Mccloy R; Murphy A; Field A; Watkins N; Powell J, 2021, 'P60.01 Single-Cell Transcriptomics to Assess Response to Immunotherapy in Advanced Lung Cancer ex-vivo: Developing a Functional Predictive Assay', Journal of Thoracic Oncology, 16, pp. S540 - S541, http://dx.doi.org/10.1016/j.jtho.2021.01.960

Kott KA; Vernon ST; Hansen T; de Dreu M; Das SK; Powell J; de St Groth BF; Di Bartolo BA; McGuire HM; Figtree GA, 2020, 'Single-cell immune profiling in coronary artery disease: The role of state-of-the-art immunophenotyping with mass cytometry in the diagnosis of atherosclerosis', Journal of the American Heart Association, 9, http://dx.doi.org/10.1161/JAHA.120.017759

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