By Professor Lei Zhang

Journal articles

Zhang Y; Deng H; Zu J; Deng Y; Tan J; Yang Z; Jiao Y; Cui X; Zhang L; Ji F; Wang Y, 2025, 'Global spatiotemporal trends and influencing factors of type 2 diabetes mellitus mortality: estimates and predictions from 1990 to 2040', Frontiers in Endocrinology, 16, http://dx.doi.org/10.3389/fendo.2025.1601089

Lu F; She B; Zhao R; Li G; Hu Y; Liu Y; Zhao M; Zhang L, 2025, 'Identifying High-Risk Populations for Sexually Transmitted Infections in Chinese Men Who Have Sex With Men: A Cluster Analysis', Open Forum Infectious Diseases, 12, http://dx.doi.org/10.1093/ofid/ofae754

Yusufu M; Friedman DS; Kang M; Padhye A; Shang X; Zhang L; Shi D; He M, 2025, 'Retinal vascular fingerprints predict incident stroke: findings from the UK Biobank cohort study', Heart, 111, pp. 306 - 313, http://dx.doi.org/10.1136/heartjnl-2024-324705

Bao Y; Liu H; Lu Q; Sun Y; Wang L; Su S; Lu P; Wang M; Ma T; Xie X; Wang W; Wang L; Zhai Y; Lu F; Wei Y; Li R; Ding M; Yan Y; Jia S; Zhang X; Yang J; Zhang L, 2025, 'Sex- and age-specific multimorbidity networks in middle-aged inpatients: A network-based comparative study between China and the United Kingdom', Innovation in Aging, 9, http://dx.doi.org/10.1093/geroni/igaf090

King AJ; Soe NN; Latt PM; Zhang L; Temple-Smith M; Maddaford K; Fairley CK; Chow EPF; Phillips TR, 2025, 'Sexual health service users’ perspectives on artificial intelligence applications for identification of lesions associated with sexually transmissible infections: A qualitative study', Digital Health, 11, http://dx.doi.org/10.1177/20552076251361749

Yang C; Lv M; Li Y; He Y; Zhang S; Zhang G; Lan J; Guo Z; Cheng Y; Yang Y; Sun J; Ma L; Zhang L, 2025, 'The interactions between psychological stress, gut microbiota, and fecal metabolites: A longitudinal multi-omics study in Chinese adolescents', Current Research in Microbial Sciences, 9, http://dx.doi.org/10.1016/j.crmicr.2025.100498

Shu Y; Shi Z; Wang W; Dou L; Zhang L; Wu M, 2025, 'Adverse childhood experiences, childhood socioeconomic status, and subsequent high myopia: Results from six universities in China', Child Abuse & Neglect, 169, pp. 107636, http://dx.doi.org/10.1016/j.chiabu.2025.107636

Zhao X; Zhang L; Zhang X; Liu X; Zhang Y; Liu Y; Tian X; Men X; Lv L; Feng Y; Song J; Xie T; Liu S; Zhang Y, 2025, 'Anti-CD19 chimeric antigen receptor T cell therapy achieved rapid and sustained remission in a patient with systemic lupus erythematosus-associated refractory immune thrombocytopenia.', Clinical and Experimental Rheumatology, 43, pp. 2001 - 2002, http://dx.doi.org/10.55563/clinexprheumatol/pn0yyk

Xue F; Hu Y; Yang R; Sun J; Yang L; Wang X; Yu Z; Zhu T; Zhou H; Zhou Z; Yan Z; Du X; Zheng C; Liu W; Zhou R; Dai J; Yin J; Wang H; Tang LV; Chen S; Cheng H; Zhu M; Wang S; Song Y; Zhang P; Zhang L; Society of Hematology CMAHTCCNOCOBOTAHGC, 2025, 'Chinese guidance for the clinical application of adeno-associated virus vector-based gene therapy for hemophilia B (2025)', Blood Science, 7, pp. e00257, http://dx.doi.org/10.1097/bs9.0000000000000257

Wang M; Zhang L; Novak SW; Yu J; Gallina IS; Xu LL; Lim CK; Fernandes S; Shokhirev MN; Williams AE; Saxena MD; Coorapati S; Parylak SL; Quintero C; Molina E; Andrade LR; Manor U; Gage FH, 2025, 'Morphological diversification and functional maturation of human astrocytes in glia-enriched cortical organoid transplanted in mouse brain', Nature Biotechnology, 43, pp. 52 - 62, http://dx.doi.org/10.1038/s41587-024-02157-8

Mesa RA; Gill H; Xiao Z; Komatsu N; Qin A; Tashi T; Zhang L; Jin J; Kirito K; Ohishi K; Shirane S; Shih L-Y; Lee S-E; Teo WZY; Maze D; Oh S; Sato T; Shih W; Mascarenhas J; Masarova L; Group S-ES, 2025, 'Ropeginterferon alfa-2b versus anagrelide for the treatment of essential thrombocythemia: Topline results of the phase 3 SURPASS-ET trial.', Journal of Clinical Oncology, 43, pp. 6500 - 6500, http://dx.doi.org/10.1200/jco.2025.43.16_suppl.6500

Bi J; Mo W; Liu M; Song Y; Xiao Q; Fan S; Wang W; Shi T; Zheng Y; Lian J; Liu R; Chen B; Huang X; Li P; Zhao Z; Shi J; Zhang L; Su G; Zhang N; Lu W, 2025, 'Systematic decoding of functional enhancer connectomes and risk variants in human glioma', Nature Cell Biology, 27, pp. 1838 - 1847, http://dx.doi.org/10.1038/s41556-025-01737-3

Gan C; Leng M; Liu Y; Zheng Z; He S; Qiao W; Xiao L; Xiao Y; Ye J; Zhou L; Zhou J; Xiao B; Zhao W; Yang J; Wu A; Zhang H; Hu H; Cen X; Qian Z; Dong H; Valencia CA; Dai L; Chow HY; Zhang L; Dong B, 2025, 'The combination of rAAV pseudo-lipid nanoparticle and triamcinolone acetonide enables multi-administration to liver', Molecular Therapy Advances, 33, pp. 101399, http://dx.doi.org/10.1016/j.omtm.2024.101399

Yang H; Yang Z; Zhang L; Yang Y; Zhou D; Li D; Zhang J; Wang Z, 2025, 'Trans-Driver: A Deep Learning Approach for Cancer Driver Gene Discovery With Multi-Omics Data', IEEE Transactions on Computational Biology and Bioinformatics, 22, pp. 3065 - 3076, http://dx.doi.org/10.1109/tcbbio.2025.3612010

Soe NN; Towns JM; Latt PM; Woodberry O; Chung M; Lee D; Ong JJ; Chow EPF; Zhang L; Fairley CK, 2024, 'Accuracy of symptom checker for the diagnosis of sexually transmitted infections using machine learning and Bayesian network algorithms', BMC Infectious Diseases, 24, http://dx.doi.org/10.1186/s12879-024-10285-4

Mahe J; Xu A; Liu L; Hua L; Tu H; Huo Y; Huang W; Liu X; Wang J; Tang J; Zhao Y; Liu Z; Hong Q; Ye R; Hu P; Jia P; Huang J; Kong X; Ge Z; Xu A; Wu L; Du C; Shi F; Cui H; Wang S; Li Z; Wang L; Zhang L; Zhang L, 2024, 'Association between weekend warrior physical activity pattern and all-cause mortality among adults living with type 2 diabetes: a prospective cohort study from NHANES 2007 to 2018', Diabetology and Metabolic Syndrome, 16, http://dx.doi.org/10.1186/s13098-024-01455-0

Sun J; She B; Latt PM; Ong JJ; Xu X; Bao Y; Fairley CK; Zhang L; Tang W; Zhang L, 2024, 'Comparing the impact of sexualised drug use with and without chemsex on sexual behaviours among men who have sex with men in China: a national multi-site cross-sectional study', Sexual Health, 21, http://dx.doi.org/10.1071/SH24173

Adawiyah RA; Bradshaw CS; Vodstrcil LA; Fairley CK; Zhang L; Ong JJ, 2024, 'Cost-effectiveness of resistance-guided therapy for Mycoplasma genitalium in Australia', Scientific Reports, 14, http://dx.doi.org/10.1038/s41598-024-63056-1

Zhang X; Li D; Ye S; Liu S; Ma S; Li M; Peng Q; Hu L; Shang X; He M; Zhang L, 2024, 'Decoding the genetic comorbidity network of Alzheimer's disease', Biodata Mining, 17, http://dx.doi.org/10.1186/s13040-024-00394-w

Wang Y; Liu C; Hu W; Luo L; Shi D; Zhang J; Yin Q; Zhang L; Han X; He M, 2024, 'Economic evaluation for medical artificial intelligence: accuracy vs. cost-effectiveness in a diabetic retinopathy screening case', Npj Digital Medicine, 7, http://dx.doi.org/10.1038/s41746-024-01032-9

Soe NN; Yu Z; Latt PM; Lee D; Ong JJ; Ge Z; Fairley CK; Zhang L, 2024, 'Evaluation of artificial intelligence-powered screening for sexually transmitted infections-related skin lesions using clinical images and metadata', BMC Medicine, 22, http://dx.doi.org/10.1186/s12916-024-03512-x

Zhang Y; Goh SM; Tapa J; Johnson CC; Chow EPF; Zhang L; Phillips T; Fairley CK; Ong JJ, 2024, 'Linkage to care and prevention after HIV self-testing: a systematic review and meta-analysis', Journal of the International AIDS Society, 27, http://dx.doi.org/10.1002/jia2.26388

Yang S; Liu R; Xin Z; Zhu Z; Chu J; Zhong P; Zhu Z; Shang X; Huang W; Zhang L; He M; Wang W, 2024, 'Plasma Metabolomics Identifies Key Metabolites and Improves Prediction of Diabetic Retinopathy: Development and Validation across Multinational Cohorts', Ophthalmology, 131, pp. 1436 - 1446, http://dx.doi.org/10.1016/j.ophtha.2024.07.004

Latt PM; Soe NN; King AJ; Lee D; Phillips TR; Xu X; Chow EPF; Fairley CK; Zhang L; Ong JJ, 2024, 'Preferences for attributes of an artificial intelligence-based risk assessment tool for HIV and sexually transmitted infections: a discrete choice experiment', BMC Public Health, 24, http://dx.doi.org/10.1186/s12889-024-20688-2

Ye S; Ma S; Liu S; Huang Y; Li D; Li M; Su T; Luo J; Zhang C; Shi D; Hu L; Zhang L; Yu H; He M; Shang X; Zhang X, 2024, 'Shared whole environmental etiology between Alzheimer’s disease and age-related macular degeneration', Npj Aging, 10, http://dx.doi.org/10.1038/s41514-024-00162-4

Li M; Liu S; Ma S; Shang X; Zhang X; Jason H; Huang Y; Kiburg K; Zhao K; Hu G; Zhang L; Yu H; He M; Zhang X, 2024, 'Network-based hub biomarker discovery for glaucoma', BMJ Open Ophthalmology, 9, http://dx.doi.org/10.1136/bmjophth-2024-001915

Fu R; Liu X; Qu X; Xue F; Liu W; Chen Y; Sun T; Ju M; Dong H; Gu W; Dai X; Yang R; Zhang L, 2024, 'A Prospective Open-Label, Single-Arm Study to Evaluate the Efficacy and Safety of Lusutrombopag in Chinese Adults with Persistent or Chronic Primary Immune Thrombocytopenia', Blood, 144, pp. 5438 - 5438, http://dx.doi.org/10.1182/blood-2024-204932

Feng X; Meng M; Sun Z; Zhang X; Zhang L; Zhang M, 2024, 'Cytokine Patterns for Secondary HLH: Experiences from a Single Center', Blood, 144, pp. 4375 - 4375, http://dx.doi.org/10.1182/blood-2024-207671

Yan Z; Zou D; Qian W; Lu Y; Li Y; Ji D; Zhu X; Mei H; Li P; Qu C; Zhang L; Zhou K; Jing H; Niu T; Ji C; Li L; Yang H; Li F; Wang W; Xu K; Zhao J; Wu D; Hu Y; Zhao W, 2024, 'Efficacy and Safety of Axicabtagene Ciloleucel (Axi-cel) for the Treatment of Relapse/Refractory Non-Hodgkin's Lymphoma: Real-World Data in Chinese Population', Blood, 144, pp. 5115 - 5115, http://dx.doi.org/10.1182/blood-2024-207186

Kuter DJ; Ghanima W; Cooper N; Liebman HA; Zhang L; Hu Y; Miyakawa Y; Morales Galindo LE; Basquiera AL; Tan CW; Saydam G; Hütter-Krönke ML; Chai-Adisaksopha C; Gomez-Almaguer D; Tran H; Shin H-J; Pascual Izquierdo MC; Kirgner I; Lucchini E; Kuzmina G; Audia S; Cordoba M; Diab R; Yao M; Lee MJ; Daak A, 2024, 'Efficacy and Safety of Oral Bruton Tyrosine Kinase Inhibitor (BTKi) Rilzabrutinib in Adults with Previously Treated Immune Thrombocytopenia (ITP): A Phase 3, Placebo-Controlled, Parallel-Group, Multicenter Study (LUNA 3)', Blood, 144, pp. 5 - 5, http://dx.doi.org/10.1182/blood-2024-199718

Zhang J; Chen J; Yang R; Zhang L, 2024, 'Machine Learning Analysis Was Conducted to Construct a Novel Model for Modulating the Clinical Manifestations and Predicting the Response to Glucocorticoids in Immune Thrombocytopenia', Blood, 144, pp. 2570 - 2570, http://dx.doi.org/10.1182/blood-2024-203542

Yang Y; Li H; Liu X; Wang H; Zhang L; Yang R, 2024, 'Multi-Omics Integration Analysis Identifies Lipoproteins As Biomarkers for Glucocorticoid Response in Immune Thrombocytopenia', Blood, 144, pp. 2553 - 2553, http://dx.doi.org/10.1182/blood-2024-203209

Chen Y; Sun T; Gao D; Wang W; Zhou Z; Gao G; Wang Y; Zhou H; Song Y; Lai Y; Yan Z; Yan J; Bai J; Zhang L, 2024, 'Optimized Recombinant Human Thrombopoietin(rhTPO) Regimen Versus Eltrombopag for Pre-Treated Patients with Primary Immune Thrombocytopenia: Interim Results from a Prospective, Multicenter, Randomized Trial (TE-ITP study)', Blood, 144, pp. 3937 - 3937, http://dx.doi.org/10.1182/blood-2024-202716

Yan J; Wang B; Wei Y; Zhang S; Zhang L; Li L; Li X; Fu X; Wang X; Sun Z; Zhang X; Zhang M, 2024, 'Outcomes and Prognostic Factors of the Alternative Regimens for Angioimmunoblastic T Cell Lymphoma: A Retrospective Study', Blood, 144, pp. 6408 - 6408, http://dx.doi.org/10.1182/blood-2024-206732

Liu W; Pei X; Xu B; Dai X; Xue F; Chen L; Wang Y; Chen Y; Liu X; Fu R; Wang W; Chi Y; Li H; Yang R; Zhang L, 2024, 'Prophylactic Administration of Glucocorticoids and Tacrolimus in AAV8-F8 Gene Therapy of Severe Haemophilia-a Achieved a Significant Long-Term Efficacy', Blood, 144, pp. 3583 - 3583, http://dx.doi.org/10.1182/blood-2024-199915

Zhang X; Fan M; Wang W; Wu J; Ma S; Dong M; Zhu L; Wu X; Feng X; Li X; Li L; Sun Z; Wang X; Fu X; Li Z; Yan J; Chang Y; Yu H; Nan F; Zhou Z; Ding M; Zhang J; Zhang L; Zhang M, 2024, 'Strikingly Reduced Toxicities of Fotemustine-Based Chemotherapeutics Than High-Dose Methotrexate-Containing Regimens with Comparable Efficacy', Blood, 144, pp. 6458 - 6458, http://dx.doi.org/10.1182/blood-2024-202107

Amhare AF; Shen M; Zou Z; Xia R; Han J; Gao L; Zhang L, 2024, 'Assessing the impact of COVID-19 on HIV care cascade for people living with HIV in Ethiopia: a retrospective longitudinal study', BMJ Open, 14, http://dx.doi.org/10.1136/bmjopen-2024-084244

Zou Z; Fairley CK; Ong JJ; Shen M; Chow EPF; Liu H; Xia R; Li R; Hocking J; Zhuang G; Zhang L, 2024, 'Impact of achieving WHO's 90-70-90 targets on cervical cancer elimination and potential benefits in preventing other HPV-related cancers in China: a modelling study', Eclinicalmedicine, 77, http://dx.doi.org/10.1016/j.eclinm.2024.102878

Shen M; Zhang L, 2024, 'The third generation modified vaccinia Ankara vaccine is effective in preventing the transmission of mpox', Lancet Regional Health Europe, 45, http://dx.doi.org/10.1016/j.lanepe.2024.101052

Li H; Liang X; Peng Y; Liu Z; Zhang L; Wang P; Jin M; Wilson K; Garvin MR; Wu K; Xiao Y, 2024, 'Novel Mito-Nuclear Combinations Facilitate the Global Invasion of a Major Agricultural Crop Pest', Advanced Science, 11, http://dx.doi.org/10.1002/advs.202305353

She B; Lu F; Zhao R; Lin S; Sun J; He S; Liu Y; Su S; Zhang L, 2024, 'Examining the Effects of PrEP Use on Sexual Behaviors and Sexually Transmitted Infections Among Chinese Men who have Sex with Men: A Cross-Sectional Study', AIDS and Behavior, 28, pp. 3128 - 3138, http://dx.doi.org/10.1007/s10461-024-04398-9

Hu C; Guo CL; Lau HCH; Shi F; Zhang Z; Guo G; Liu G; Chen Y; Lau LHS; Zhang L; Sun X; Wong SH; She J; Yu J, 2024, 'Appendix removal affects the subsequent cancer risk in Asian adults: A territory-wide population-based cohort study', Cancer Letters, 598, http://dx.doi.org/10.1016/j.canlet.2024.217087

Moon B-S; Huang D; Gao F; Cai M; Lyu G; Zhang L; Chen J; Lu W, 2024, 'Correction: Long range inter-chromosomal interaction of Oct4 distal enhancer loci regulates ESCs pluripotency.', Cell Death Discov, 10, pp. 370, http://dx.doi.org/10.1038/s41420-024-02125-w

Hu Y; Zhao R; Li G; Liu Y; Lu F; She B; Zhao M; Zhang L, 2024, 'Associations between antibacterial mouthwash use with sexual behaviours and sexually transmitted infections among Chinese men who have sex with men: A cross-sectional study', Sexual Health, 21, http://dx.doi.org/10.1071/SH24083

He X; Huang AH; Lv F; Gao X; Guo Y; Liu Y; Hu X; Xie J; Gao N; Jiao Y; Wang Y; Zu J; Zhang L; Ji F; Yeo YH, 2024, 'Trends in diabetic ketoacidosis- and hyperosmolar hyperglycemic state-related mortality during the COVID-19 pandemic in the United States: A population-based study', Journal of Diabetes, 16, http://dx.doi.org/10.1111/1753-0407.13591

Tran A; Tran N; Tapa J; Tieosapjaroen W; Fairley CK; Chow EPF; Zhang L; Baggaley RC; Johnson CC; Jamil MS; Ong JJ, 2024, 'A typology of HIV self-testing support systems: a scoping review', Sexual Health, 21, http://dx.doi.org/10.1071/SH24037

Ma L; Li Y; Li G; Sun J; Zhang X; Shi Z; Yan Y; Duan Y; Wang J; Li Z; Zhang L, 2024, 'Adiposity indicators exhibit depot- and sex-specific associations with multimorbidity onset: A cohort study of the UK Biobank', Diabetes Obesity and Metabolism, 26, pp. 2890 - 2904, http://dx.doi.org/10.1111/dom.15610

Chen H; Zhang L; Shi X; Zhou Z; Fang X; Yang H; Hunter DJ; Ding C; Zhu Z, 2024, 'Evaluation of Osteoarthritis Disease Burden in China During 1990–2019 and Forecasting Its Trend Over the Future 25 Years', Arthritis Care and Research, 76, pp. 1006 - 1017, http://dx.doi.org/10.1002/acr.25322

Shi Y; Fang N; Wu Y; Xu H; Ning A; Zhang W; Liu Y; Tao X; Chen Q; Tian T; Zhang L; Chu M; Cui J, 2024, 'NEDD4L mediates ITGB4 ubiquitination and degradation to suppress esophageal carcinoma progression', Cell Communication and Signaling, 22, pp. 302, http://dx.doi.org/10.1186/s12964-024-01685-9

Shi Y; Gui L; Cheng Y; Wang H; Cao J; Li Y; Yu Y; Gao Y; Li Z; Shen J; Zhang L; Zhang Q; Pan Q; Wang Z; Ke X; He H; Guo S; Wang Y; Xu X; Zou L, 2024, 'A phase II multicenter study of abexinostat, an oral histone deacetylase inhibitor, in patients with relapsed/refractory follicular lymphoma.', Journal of Clinical Oncology, 42, pp. 7059 - 7059, http://dx.doi.org/10.1200/jco.2024.42.16_suppl.7059

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