By Professor Lei Zhang

Preprints

Zhao M; Tu Z; Zhao R; Gu Y; Liu H; Wei Y; Su S; Ong JJ; Ji F; Zhang L, 2026, Global Trends and Disparities in HIV Pre-Exposure Prophylaxis Acceptance Among Key Populations: A Systematic Review and Meta-Analysis, http://dx.doi.org/10.2139/ssrn.6729041

Cao Y; Fairley C; Wu D; Jiang M; Si L; Gu Y; Jiang S; Wang J; Ma Y; Zhao M; Zhang Y; Wu J; Jin D; Ji F; Guo H; Zhuang G; Shen M; Zou Z; Zhang L, 2026, Population Impact and Cost-Effectiveness of Risk-Stratified Cervical Cancer Screening by HPV Vaccination Status in China: A Modelling Study, http://dx.doi.org/10.2139/ssrn.6441011

Zhang L; Wen Q; Sun T; Yu D; Mankai J; Xiaofan L; Huiyuan L; Fu R; Liu W; Xue F; Dong H; Xinyue D; Wang W; Chi Y; Renchi Y; Chen Y, 2025, A Proteomics-Driven Machine Learning Tool for Distinguishing ET from pre-PMF, http://dx.doi.org/10.21203/rs.3.rs-7128322/v1

Shi Y; Zhang Y; Zhang L; Zhang H; Sharma M; Zhang L; Zhao Y, 2025, Digital Disadvantage in Nutrition Services: How Environmental Literacy Gaps Limit Elderly Chinese with Chronic Diseases, http://dx.doi.org/10.21203/rs.3.rs-6653933/v1

Latt PM; Ray A; Lu H; Soe NN; Xu X; Bao Y; Ong JJ; Chow EPF; Varma R; Zhang L; Fairley CK, 2025, External Validation of a Web- and Artificial Intelligence-Based HIV/STI Risk Assessment Tool: Performance Evaluation Using Data from Sydney Sexual Health Centre, http://dx.doi.org/10.21203/rs.3.rs-6757880/v1

Soe NN; Kusnandar II; Latt PM; Fairley CK; Chow EPF; Maatouk I; Johnson CC; Shah P; Peters R; Subissi L; Zhang L; Ong JJ, 2025, Clinical Applications of AI in Sexually Transmitted Infection and Anogenital Dermatoses in Sexual Health: A Systematic Review and Meta-Analysis, http://dx.doi.org/10.21203/rs.3.rs-6002285/v1

Wang Y; Hu W; Zhou K; Liu C; Zhang J; Zhu Z; Joseph S; Yin Q; Luo L; Han X; He M; Zhang L, 2025, What is the role of human decisions in a world of artificial intelligence: an economic evaluation of human-AI collaboration in diabetic retinopathy screening, http://dx.doi.org/10.48550/arxiv.2503.20160

King AJ; Soe NN; Latt PM; Zhang L; Temple-Smith M; Maddaford K; Fairley CK; Chow EPF; Phillips TR, 2025, Sexual Health Service Users’ Perspectives on Artificial Intelligence Applications for Identification of Lesions Associated with Sexually Transmissible Infections: A Qualitative Study, http://dx.doi.org/10.21203/rs.3.rs-5944037/v1

Latt PM; Soe NN; Fairley CK; Chow EPF; Johnson C; Shah P; Maatouk I; Zhang L; Ong J, 2025, Machine Learning for Personalised Risk Assessment of HIV, Syphilis, Gonorrhoea, and Chlamydia: A Systematic Review and Meta-Analysis, http://dx.doi.org/10.2139/ssrn.5089250

Yusufu M; Jin S; Shang X; Zhang L; shi D; He M, 2025, Neurovascular Retinomics Improves Multi-Disease Prediction, http://dx.doi.org/10.2139/ssrn.5103720

Latt PM; Aung ET; Htaik K; Soe NN; Lee D; King AJ; Fortune R; Ong JJ; Chow EPF; Bradshaw CS; Rahman R; Deneen M; Dobinson S; Randall C; Zhang L; Fairley CK, 2024, Real-World Evaluation of Artificial Intelligence (AI) Chatbots for Providing Sexual Health Information: A Consensus Study Using Clinical Queries, http://dx.doi.org/10.21203/rs.3.rs-5190887/v1

Wu H; Shi F; Hu C; Zhang L; Qu P; She J, 2024, The effect of 5-item modified frailty index on clinical outcomes in elderly rectal cancer patients after curative surgery, http://dx.doi.org/10.21203/rs.3.rs-4866682/v1

Zhang X; Li D; Ye S; Liu S; Ma S; Li M; Peng Q; Hu L; Shang X; He M; Zhang L, 2024, Decoding the Genetic Comorbidity Network of Alzheimer's Disease, http://dx.doi.org/10.21203/rs.3.rs-4820203/v1

SUI L; ZHANG D; WANG W; LI D; LIU Y; XUE M; HAO J; WANG M; ZHANG L, 2024, Relationship between physical activity, sleep quality, and frailty in middle-aged and older adults: a cross-sectional study Running title: The correlation between physical activity, sleep quality, and frailty, http://dx.doi.org/10.21203/rs.3.rs-4230718/v1

Su S; Guo L; Ma T; Sun Y; Song A; Wang W; Gu X; Wu W; Xie X; Wang L; Zhang L; He S; Zhang L; Yang J, 2024, Association of ABO blood group with respiratory diseases hospitalisation and severe outcomes: a retrospective cohort study in blood donors, http://dx.doi.org/10.22541/au.170669689.91761775/v1

Zhang L; Li Y; Chen J; Sun T; Fu R; Liu X; Xue F; Liu W; Chen Y; Ju M; Dai X; Li H; Wang W; Chi Y, 2024, Genetically Determined Telomere Length and Risk for Haematologic Diseases: Results from Large Prospective Cohorts and Mendelian Randomization Analysis, http://dx.doi.org/10.21203/rs.3.rs-3866462/v1

Soe NN; Towns J; Latt PM; Woodberry O; Nicholson A; Chung M; Lee D; Ong J; Chow EPF; Zhang L; Fairley C, 2024, Accuracy of Symptom Checker for the Diagnosis of Sexually Transmitted Infections using Machine Learning and Bayesian Network Algorithms, http://dx.doi.org/10.21203/rs.3.rs-5086144/v1

Mahe J; Xu A; Liu L; Hua L; Tu H; Huo Y; Huang W; Liu X; Wang J; Tang J; Zhao Y; Liu Z; Hong Q; Ye R; Hu P; Jia P; Huang J; Kong X; Ge Z; Xu A; Wu L; Du C; Shi F; Cui H; Wang S; Li Z-H; Wang L; Zhang L; Zhang L, 2024, Association of Weekend Warrior Physical Activity Pattern with All-Cause Mortality Among Adults with Type 2 Diabetes: A Prospective Cohort Study from NHANES 2007 to 2018, http://dx.doi.org/10.2139/ssrn.4754926

He S; Yao N; Li R; Wang J; Zhong W; Wang J; Wang H; Xie L; Zhuang G; Chen T; Zhang L; Shen M, 2024, Determining the Initiation Time of Peripartum Antiviral Prophylaxis Among Pregnant Women with Chronic Hepatitis B Infection: A Mathematical Modelling Study Based on Real-World Clinical Data, http://dx.doi.org/10.2139/ssrn.4721663

Chua T-P; Vodstrcil LA; Murray GL; Plummer E; Jensen JS; Unemo M; Chow EPF; Low N; Whiley DM; Sweeney EL; Hocking JS; Danielewski JA; Garland SM; Fairley CK; Zhang L; Bradshaw C; Machalek DA, 2024, Evolving Patterns of Macrolide and Fluoroquinolone Resistance in Mycoplasma Genitalium: An Updated Global Systematic Review and Meta-Analysis, http://dx.doi.org/10.2139/ssrn.4764790

She B; Sun J; Lu F; Lin S; Liu Y; Li G; Hu Y; Tang W; Tan R; Ong J; Su S; Zhang L, 2024, Identifying subgroups of Chinese men who have sex with men based on sexual behavior and drug use patterns using a clustering analysis approach, http://dx.doi.org/10.21203/rs.3.rs-5286116/v1

Zou Z; Fairley CK; Ong J; Shen M; Chow EPF; Liu H; Xia R; Li R; Hocking JS; Zhuang G; Zhang L, 2024, Impact of Achieving WHO's 90-70-90 Targets on Cervical Cancer Elimination and Potential Benefits in Preventing Other HPV-Related Cancers in China, http://dx.doi.org/10.2139/ssrn.4773146

Soe NN; Latt PM; Lee D; Towns J; King AJ; Chow EPF; Ong J; Zhang L; Fairley CK, 2024, Impact of Result Displays in an Anogenital Symptom Checker App on Health-Seeking Behaviours: A Cross-Sectional, Vignette-Based Study, http://dx.doi.org/10.2139/ssrn.4975397

Zhu Z; Zhong X; Yang S; Liu R; Xin Z; Zhu Z; Shang X; Zhang L; Huang W; Wang W, 2024, Large-Scale Proteome-Wide Mendelian Randomization Identifies Novel Proteins for Glaucoma and Related Traits, http://dx.doi.org/10.2139/ssrn.4804329

Zhu Z; Zhong X; Yang S; Liu R; Xin Z; Zhu Z; Shang X; Zhang L; Huang W; Wang W, 2024, Large-Scale Proteome-Wide Mendelian Randomization Identifies Novel Proteins for Glaucoma and Related Traits, http://dx.doi.org/10.2139/ssrn.4788501

Zhang Y; Goh SM; Tapa J; Johnson C; Chow EPF; Zhang L; Phillips TR; Fairley CK; Ong J, 2024, Linkage to Care and Prevention after HIV Self-Testing: A Systematic Review and Meta-Analysis, http://dx.doi.org/10.2139/ssrn.4716778

Liu R; Yang S; Zhong X; Xin Z; Zhu Z; Zhu Z; Shang X; Zhang L; He M; Huang W; Wang W, 2024, Metabolomic Signature of Frailty Prognosticate Diabetes and Vascular Outcomes in UK Biobank and Chinese Cohort, http://dx.doi.org/10.2139/ssrn.4713364

Han Y; Jing F; Ren H; Xie Y; Ni Y; Zhou Y; Xu Z; Wu D; Cheng W; Zhang L; Wong WCW; Zhang Q; Tang W; Zhou J, 2024, Multimorbidity Patterns Among Chinese Men Who Have Sex with Men: A Multi-Sectional Comparative Network Analysis, http://dx.doi.org/10.2139/ssrn.5058485

Lai H; Ong J; Traeger MW; Fairley CK; Howden B; Stoove M; Shen M; Zhang L, 2024, Population Impact and Cost-Effectiveness of Doxycycline Post-Exposure Prophylaxis in Preventing the Sexually Transmitted Infections Among Gay, Bisexual, and Other Men Who Have Sex with Men in Australia: A Mathematical Modelling Study, http://dx.doi.org/10.2139/ssrn.5068588

Yusufu M; Vingrys A; Shang X; Zhang L; Shi D; Congdon N; He M, 2024, Population-based Normative Reference for Retinal Microvascular Atlas, http://dx.doi.org/10.1101/2024.10.25.24316087

Latt PM; Soe NN; King AJ; Lee D; Phillips TR; Xu X; Chow EPF; Fairley CK; Zhang L; Ong J, 2024, Preferences for Attributes of an Artificial Intelligence-Based Risk Assessment Tool for HIV and Sexually Transmitted Infections: A Discrete Choice Experiment, http://dx.doi.org/10.2139/ssrn.4808363

Yusufu M; Weinreb R; Kang M; Vingrys A; Shang X; Zhang L; Shi D; He M, 2024, Relationship between Retinal Vessels and OCT-Derived Retinal Neural Parameters, http://dx.doi.org/10.1101/2024.09.23.24313858

Zhang X; Ye S; Ma S; Liu S; Huang Y; Li D; Li M; Su T; Luo J; Zhang C; Shi D; Hu L; Zhang L; Yu H; He M; Shang X, 2024, Shared whole environmental etiology between Alzheimer's disease and Age-related macular degeneration, http://dx.doi.org/10.21203/rs.3.rs-3869235/v1

Lai H; Fairley CK; Li R; Chen MY; Chow EPF; Donovan B; Callander D; Guy R; Tran J; Aung ET; Shen M; Zhang L, 2024, The Impact and Cost-Effectiveness of Regular Self-Digital Anorectal Examination on Syphilis Among Gay, Bisexual, and Other Men Who Have Sex with Men: A Mathematical Modelling Study, http://dx.doi.org/10.2139/ssrn.4902602

Tieosapjaroen W; Tran A; Maisano M; Kim C-M; Fairley CK; Chow EPF; Zhang L; Phillips TR; Bissessor M; Ong J, 2024, Trend and Associated Factors for Late and Advanced HIV Diagnoses in 2011-2022 in Melbourne, Australia, http://dx.doi.org/10.2139/ssrn.5051974

Zhang X; Li D; Ye S; Liu S; Ma S; Li M; Peng Q; Hu L; Shang X; He M; Zhang L, 2024, Unraveling the Genetic Comorbidity Landscape of Alzheimer’s Disease, http://dx.doi.org/10.1101/2024.03.05.583453

Soe NN; Latt PM; Lee D; Yu Z; Schmidt M; Bissessor M; Aung ET; Ge Z; Ong J; Fairley CK; Zhang L, 2024, Using Deep Learning Systems for Diagnosing Common Skin Lesions in Sexual Health, http://dx.doi.org/10.2139/ssrn.4785371

Soe NN; Latt PM; King AJ; Lee D; Phillips TR; Fairley CK; Zhang L; Ong JJ, 2024, What Do People Want from an AI-Assisted App for Diagnosing Images of Sexually Transmitted Infections: A Discrete Choice Experiment, http://dx.doi.org/10.2139/ssrn.4838984

Soe NN; Yu Z; Latt PM; Lee D; Samra RS; Ge Z; Rahman R; Sun J; Ong JJ; Fairley CK; Zhang L, 2023, Using AI to Differentiate Mpox From Common Skin Lesions in a Sexual Health Clinic: Algorithm Development and Validation Study (Preprint), http://dx.doi.org/10.2196/preprints.52490

Su S; Sun Y; Gu X; Wu W; Su X; Ma T; Song A; Xie X; Wang L; Cheng Q; Guo L; Zhang L; Yang J, 2023, Exploration of the Healthy Donor Effect Among 0.6 Million Blood Donors in China: Longitudinal Study (Preprint), http://dx.doi.org/10.2196/preprints.48617

guo L; Liu Y; Zhang L; Li Q; Qiu H; Guo Y; Shi Q, 2023, Massive airway hemorrhage in severe COVID-19 and the role endotracheal tube clamping, http://dx.doi.org/10.21203/rs.3.rs-2393880/v1

Wang L; Su S; Yang J; Zhang L; Yu Y; Su X; Gu X; Ma T; Xie X; Wu W; Song A; Cheng Q; Sun Y, 2023, Association between ABO Blood Groups and the Top 25 Fatal Diseases in China: A Retrospective Cohort Study with Cluster Analysis of 1.7 Million Blood Donors, http://dx.doi.org/10.2139/ssrn.4452006

Adawiyah R; Vodstrcil LA; Bradshaw C; Fairley CK; Zhang L; Ong J, 2023, Cost-Effectiveness of Resistance Guided Therapy for Mycoplasma Genitalium for Women, Men Who Have Sex with Men (MSM) and Men Who Have Sex with Women (MSW) in Australia, http://dx.doi.org/10.2139/ssrn.4673221

Li R; Lu P; Fairley C; Pagán J; Hu W; Yang Q; Zhuang G; Shen M; Li Y; Zhang L, 2023, Cost-Effectiveness of the Second COVID-19 Booster Vaccination in the United States, http://dx.doi.org/10.2139/ssrn.4320811

Zhang L; Hu C; Zhang Z; She J; Shi F, 2023, Do elderly patients with colorectal cancer benefit from surgery and different therapeutic patterns? A real-world study based on SEER database, http://dx.doi.org/10.21203/rs.3.rs-2866879/v1

Su S; Sun Y; Gu X; Wu W; Su X; Ma T; Song A; Xie X; Wang L; Cheng Q; Guo L; Zhang L; Yang J, 2023, Exploration of Health Donor Effects: A Population-Based Study of 0.6 Million Donors in China, http://dx.doi.org/10.2139/ssrn.4415676

Tieosapjaroen W; Mao L; Wong H; Prankumar SK; Chow EPF; Fairley CK; Phillips TR; Zhang L; Ong J, 2023, Factors Associated with HIV Pre-Exposure Prophylaxis Use Among Gay Asian Men in Sydney and Melbourne, Australia, http://dx.doi.org/10.2139/ssrn.4650296

Zhang X; Ma S; Shang X; Zhang X; Kong L; Jason H; Huang Y; Zhu Z; Liu S; Kiburg K; Shi D; Wang Y; Bao Y; Lai H; Wang W; Hu Y; Zhao K; Hu G; Liang H; Yu H; Zhang L; He M, 2023, Network-based hub biomarker discovery for glaucoma, http://dx.doi.org/10.21203/rs.3.rs-3033661/v1

Rubino F; McIntyre R; Chai Z; Amiel S; Alberti G; Bornstein S; Eckel R; Herman W; Khunti K; Mingrone G; Mbanya JC; Mohan V; Tan M; Zhang L; Al-Mulla F; Al-Abdulrazzaq D; Naimi TA; Alessa T; Chamseddine G; Chandrasekaran S; Hinduja A; Rhee SY; Sathish T; Zimmet P, 2023, New-Onset Diabetes and COVID-19: Evidence from a Global Clinical Registry, http://dx.doi.org/10.21203/rs.3.rs-2405391/v1

Zhao R; Fairley CK; Cook AR; Phanuphak N; He S; Tieosapjaroen W; Chow EPF; Phillips TR; Tan RKJ; Wei Y; Shen M; Zhuang G; Ong J; Zhang L, 2023, Optimizing HIV Pre-Exposure Prophylaxis and Testing Strategies in Men Who Have Sex with Men in Australia, Thailand and China: A Modelling Study and Cost-Effectiveness Analysis, http://dx.doi.org/10.2139/ssrn.4501205

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