By Professor Marina Pajic

Conference Abstracts

Tyma V; Liew Y-F; Tran A; Howell A; Ritchie S; Atlas AAPCM; Cox T; Pajic M; Herrmann D; Pereira B; Timpson P; Gordon K, 2024, 'Identifying and targeting FOLFIRINOX resistance mechanisms to improve outcomes in pancreatic cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, MA, Boston, Vol. 84, presented at AACR Special Conference in Cancer Research: Advances in Pancreatic Cancer Research, MA, Boston, 15 September 2024 - 18 September 2024, http://dx.doi.org/10.1158/1538-7445.PANCREATIC24-A067

Upton D; Fajardo DC; Omari S; Porazinski S; McLean B; Schuhmacher D; Istadi A; Kothari V; Finkelstein D; Machajewski T; Rock F; Turner S; Pajic M, 2024, 'Selective targeting of integrins αVβ8 and αVβ1 within the dynamic ecosystem of pancreatic cancer to improve the overall anti-tumor response', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CA, San Diego, Vol. 84, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), CA, San Diego, 05 April 2024 - 10 April 2024, http://dx.doi.org/10.1158/1538-7445.AM2024-6575

Pajic M; McLean B; Fajardo DC; Porazinski S; Upton DH; Schuhmacher D; Istadi A; Cox T; Timpson P; Wilcock DJ; Anderson KJ; Mason H; Guisot NE; Jones CD; Phillips C; Armer R, 2024, 'Abstract 720: Combining zelasudil, a small molecule ROCK2 inhibitor, with chemotherapy or immunotherapy improves response in preclinical models of pancreatic cancer', in Cancer Research, American Association for Cancer Research (AACR), Vol. 84, pp. 720 - 720, http://dx.doi.org/10.1158/1538-7445.am2024-720

Chacon-Fajardo D; Porazinski S; Man J; Yim H; El-Omar E; Joshua A; Pajic M, 2024, 'Abstract A029: Re-purposing non-oncology agent itraconazole to target the dynamic cellular ecosystem of pancreatic cancer', in Cancer Research, American Association for Cancer Research (AACR), Vol. 84, pp. a029 - a029, http://dx.doi.org/10.1158/1538-7445.panca2023-a029

Porazinski S; Man J; Chacon-Fajardo D; Yim H; El-Omar E; Joshua A; Pajic M, 2024, 'Abstract C017: The anti-fungal itraconazole improves immunotherapy efficacy in pancreatic ductal adenocarcinoma by reversing the immune-suppressive tumor microenvironment', in Cancer Research, American Association for Cancer Research (AACR), Vol. 84, pp. c017 - c017, http://dx.doi.org/10.1158/1538-7445.panca2023-c017

Pitiyarachchi O; Lin FP; Spooner A; Sharbeen G; Barker HP; Thornton K; Collignon E; Ballinger ML; Thomas DM; Magenau A; Porazinski S; Raina A; Sjoquist KM; Chantrill LA; Gebski V; Sowmya A; Timpson P; Pajic M; Goldstein D; Phillips PA, 2024, '1513P Impact of symptom and functional burden on survival in pancreatic ductal adenocarcinoma (PDAC)', in Annals of Oncology, Elsevier, Vol. 35, pp. s925, http://dx.doi.org/10.1016/j.annonc.2024.08.1576

Murphy KJ; Reed DA; Chambers CR; Channon LM; Pajic M; Herrmann D; Timpson P, 2023, 'Anti-fibrotic FAK 'priming' to improve contemporary chemotherapy in pancreatic cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, MA, Boston, Vol. 84, presented at AACR Special Conference - Pancreatic Cancer, MA, Boston, 27 September 2023 - 30 September 2023, http://dx.doi.org/10.1158/1538-7445.PANCA2023-B037

McLean B; Fajardo DC; Istadi A; Porazinski S; Pajic M; Pajic M, 2022, 'EFFECTIVE CO-TARGETING OF FIBROTIC AND IMMUNE MICROENVIRONMENTS TO IMPROVE THE OVERALL ANTI-TUMOUR RESPONSE IN MODELS OF ADVANCED PANCREATIC CANCER', in JOURNAL FOR IMMUNOTHERAPY OF CANCER, BMJ PUBLISHING GROUP, Vol. 10, pp. A1514 - A1514, http://dx.doi.org/10.1136/jitc-2022-SITC2022.1455

Chin VT; Nagrial A; Conway J; Vennin C; Chantrill LA; Chou A; Steinmann A; Gill AJ; Humprhis J; Drury A; Froio D; Morgan A; Biankin A; Timpson P; Pajic M, 2017, 'Effect of Rho/ROCK pathway inhibition on metastasis-free and overall survival in biomarker selected, orthotopic, patient-derived models of pancreatic cancer.', in Journal of Clinical Oncology, American Society of Clinical Oncology (ASCO), Vol. 35, pp. e15759 - e15759, http://dx.doi.org/10.1200/jco.2017.35.15_suppl.e15759

Chin VT; Conway J; Nagrial A; Chantrill LA; Chou A; Steinmann A; Gill A; Pinese M; Wu J; Johns A; Dury A; Biankin A; Timpson P; Pajic M, 2015, 'Targeting the Rho-ROCK pathway to treat pancreatic cancer: The use of unique preclinical models to ascertain the effects on cancer growth and metastasis', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, CA, San Francisco, Vol. 33, presented at Gastrointestinal Cancers Symposium, CA, San Francisco, 15 January 2015 - 17 January 2015, http://dx.doi.org/10.1200/jco.2015.33.3_suppl.312

Chin VT; Nagrial A; Chantrill LA; Chang DK; Chou A; Humprhis J; Cowley M; Wu J; DiPetro R; Watson C; Spielman C; Steinmann A; Pinese M; Pettitt J; Johns A; Waddell N; Grimmond S; Timpson P; Biankin AV; Pajic M, 2013, 'From functional genomics to precision medicine: The therapeutic potential of targeting ROCK signaling in pancreatic cancer.', in JOURNAL OF CLINICAL ONCOLOGY, LIPPINCOTT WILLIAMS & WILKINS, IL, Chicago, Vol. 31, presented at 49th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 31 May 2013 - 04 June 2013, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000335419603693&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Humphris J; Johns A; Simpson S; Chang D; Cowley MJ; Pajic M; Jones M; Simpson S; Mead S; Biankin A, 2012, 'Risk factors for pancreatic cancer in patients with and without a family history of pancreatic cancer', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY-BLACKWELL, Vol. 27, pp. 127 - 127, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000308642600262&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Pajic M; Chang DK; Kassahn KS; Wu J; Cowley M; Waddell N; Johns A; Grimmond SM; Biankin AV, 2012, 'Proffered Paper: Testing Individualised Treatment Strategies in Preclinical Models of Pancreatic Cancer', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, SPAIN, Barcelona, Vol. 48, pp. S22 - S22, presented at 22nd Biennial Congress of the European-Association-for-Cancer-Research, SPAIN, Barcelona, 07 July 2012 - 10 July 2012, http://dx.doi.org/10.1016/S0959-8049(12)70795-5

Murray J; Burkhart CA; Watt F; Pajic M; Flemming C; Smith J; Gudkov AV; Haber M; Norris MD, 2006, '169 POSTER Sensitisation of neuroblastoma tumours to chemotherapy by use of a novel class of MRP1 small molecule inhibitor', in European Journal of Cancer Supplements, Elsevier, Vol. 4, pp. 54, http://dx.doi.org/10.1016/s1359-6349(06)70175-6

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