Hybrid Sensor-based Physiological Control of an Implantable Rotary Blood Pump

The principal goal in controlling rotary blood pumps used as ventricular assist devices in heart failure patients is to mimic the natural heart behaviour so that the body's metabolic requirements are met while avoiding harmful states associated with over and under pumping. In this research we will create, evaluate and implement novel control algorithms that intelligently combine sensorless, non-invasive and invasive sensor signals to provide a robust preload sensitive flow controller for implantable rotary blood pumps that automatically adapts to varying patient conditions. Control algorithms will be developed using software and physical system modelling and validated in acute animal studies.