By Assistant Professor Loretta Lau

Journal articles

Lau LMS; Mayoh C; Xie J; Barahona P; MacKenzie KL; Wong M; Kamili A; Tsoli M; Failes TW; Kumar A; Mould EVA; Gifford A; Chow SO; Pinese M; Fletcher JI; Arndt GM; Khuong-Quang DA; Wadham C; Batey D; Eden G; Trebilcock P; Joshi S; Alfred S; Gopalakrishnan A; Khan A; Grebert Wade D; Strong PA; Manouvrier E; Morgan LT; Span M; Lim JY; Cadiz R; Ung C; Thomas DM; Tucker KM; Warby M; McCowage GB; Dalla-Pozza L; Byrne JA; Saletta F; Fellowes A; Fox SB; Norris MD; Tyrrell V; Trahair TN; Lock RB; Cowley MJ; Ekert PG; Haber M; Ziegler DS; Marshall GM; Trahair T, 2022, 'In vitro and in vivo drug screens of tumor cells identify novel therapies for high-risk child cancer', EMBO Molecular Medicine, 14, pp. emmm202114608, http://dx.doi.org/10.15252/emmm.202114608

Holmes O; Nones K; Tang YH; Loffler KA; Lee M; Patch AM; Dagg RA; Lau LMS; Leonard C; Wood S; Xu Q; Pickett HA; Reddel RR; Barbour AP; Grimmond SM; Waddell N; Pearson JV, 2022, 'qmotif: determination of telomere content from whole-genome sequence data', Bioinformatics Advances, 2, http://dx.doi.org/10.1093/bioadv/vbac005

Manoharan N; Ajuyah P; Senapati A; Wong M; Mullins A; Rodriguez M; Doyle H; McCowage G; Lau LMS; Ekert PG; Ziegler DS, 2021, 'Diffuse leptomeningeal glioneuronal tumour (DLGNT) in children: the emerging role of genomic analysis', Acta Neuropathologica Communications, 9, http://dx.doi.org/10.1186/s40478-021-01248-w

Nagabushan S; Lau LMS; Barahona P; Wong M; Sherstyuk A; Marshall GM; Tyrrell V; Wegner EA; Ekert PG; Cowley MJ; Mayoh C; Trahair TN; Crowe P; Anazodo A; Ziegler DS, 2021, 'Efficacy of MEK inhibition in a recurrent malignant peripheral nerve sheath tumor', npj Precision Oncology, 5, http://dx.doi.org/10.1038/s41698-021-00145-8

Chen YY; Dagg R; Zhang Y; Lee JHY; Lu R; La Rotta NM; Sampl S; Korkut-Demirbaş M; Holzmann K; Lau LMS; Reddel RR; Henson JD, 2021, 'The c-circle biomarker is secreted by alternative-lengthening-of-telomeres positive cancer cells inside exosomes and provides a blood-based diagnostic for alt activity', Cancers, 13, http://dx.doi.org/10.3390/cancers13215369

Xie J; Kumar A; Dolman MEM; Mayoh C; Khuong-Quang DA; Cadiz R; Wong-Erasmus M; Mould EVA; Grebert-Wade D; Barahona P; Kamili A; Tsoli M; Failes TW; Chow SO; Bhatia K; Marshall GM; Ziegler DS; Haber M; Lock RB; Tyrrell V; Lau L; Athanasatos P; Gifford AJ; Arndt G, 2021, 'The important role of routine cytopathology in pediatric precision oncology', Cancer Cytopathology, 129, pp. 805 - 818, http://dx.doi.org/10.1002/cncy.22448

Jiao W; Atwal G; Polak P; Karlic R; Cuppen E; Al-Shahrour F; Bailey PJ; Biankin AV; Boutros PC; Campbell PJ; Chang DK; Cooke SL; Deshpande V; Faltas BM; Faquin WC; Garraway L; Getz G; Grimmond SM; Haider S; Hoadley KA; Kaiser VB; Kato M; Kübler K; Lazar AJ; Li CH; Louis DN; Margolin A; Martin S; Nahal-Bose HK; Nielsen GP; Nik-Zainal S; Omberg L; P’ng C; Perry MD; Rheinbay E; Rubin MA; Semple CA; Sgroi DC; Shibata T; Siebert R; Smith J; Stein LD; Stobbe MD; Sun RX; Thai K; Wright DW; Wu CL; Yuan K; Zhang J; Danyi A; de Ridder J; van Herpen C; Lolkema MP; Steeghs N; Morris QD; Aaltonen LA; Abascal F; Abeshouse A; Aburatani H; Adams DJ; Agrawal N; Ahn KS; Ahn SM; Aikata H; Akbani R; Akdemir KC; Al-Ahmadie H; Al-Sedairy ST; Alawi M; Albert M; Aldape K; Alexandrov LB; Ally A; Alsop K; Alvarez EG; Amary F; Amin SB; Aminou B; Ammerpohl O; Anderson MJ; Ang Y; Antonello D; Anur P; Aparicio S; Appelbaum EL; Arai Y; Aretz A; Arihiro K; Ariizumi SI; Armenia J; Arnould L; Asa S; Assenov Y, 2020, 'A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns', Nature Communications, 11, http://dx.doi.org/10.1038/s41467-019-13825-8

Bailey MH; Meyerson WU; Dursi LJ; Wang LB; Dong G; Liang WW; Weerasinghe A; Li S; Li Y; Kelso S; Akbani R; Anur P; Bailey MH; Buchanan A; Chiotti K; Covington K; Creason A; Ding L; Ellrott K; Fan Y; Foltz S; Getz G; Hale W; Haussler D; Hess JM; Hutter CM; Kandoth C; Kasaian K; Kasapi M; Larson D; Leshchiner I; Letaw J; Ma S; McLellan MD; Men Y; Mills GB; Niu B; Peto M; Radenbaugh A; Reynolds SM; Saksena G; Sofia H; Stewart C; Struck AJ; Stuart JM; Wang W; Weinstein JN; Wheeler DA; Wong CK; Xi L; Ye K; Bailey MH; Niu B; Bieg M; Boutros PC; Buchhalter I; Butler AP; Chen K; Chong Z; Ding L; Drechsel O; Jonathan Dursi L; Eils R; Ellrott K; Espiritu SMG; Fan Y; Fulton RS; Gao S; Gelpi JLL; Gerstein MB; Gonzalez S; Gut IG; Hach F; Heinold MC; Hess JM; Hinton J; Hu T; Huang V; Huang Y; Hutter B; Jones DR; Jung J; Jäger N; Kim HL; Kleinheinz K; Kumar S; Kumar Y; Lalansingh CM; Letunic I; Livitz D; Ma EZ; Maruvka YE; Mashl RJ; McLellan MD; Menzies A; Milovanovic A; Nielsen MM; Ossowski S; Toon CCW; Merrett N; Pinese M; Lau L; Chou A; Biankin A; Johns A, 2020, 'Author Correction: Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples (Nature Communications, (2020), 11, 1, (4748), 10.1038/s41467-020-18151-y)', Nature Communications, 11, pp. 6232, http://dx.doi.org/10.1038/s41467-020-20128-w

Shuai S; Abascal F; Amin SB; Bader GD; Bandopadhayay P; Barenboim J; Beroukhim R; Bertl J; Boroevich KA; Brunak S; Campbell PJ; Carlevaro-Fita J; Chakravarty D; Chan CWY; Chen K; Choi JK; Deu-Pons J; Dhingra P; Diamanti K; Feuerbach L; Fink JL; Fonseca NA; Frigola J; Gambacorti-Passerini C; Garsed DW; Gerstein M; Getz G; Guo Q; Gut IG; Haan D; Hamilton MP; Haradhvala NJ; Harmanci AO; Helmy M; Herrmann C; Hess JM; Hobolth A; Hodzic E; Hong C; Hornshøj H; Isaev K; Izarzugaza JMG; Johnson R; Johnson TA; Juul M; Juul RI; Kahles A; Kahraman A; Kellis M; Khurana E; Kim J; Kim JK; Kim Y; Komorowski J; Korbel JO; Kumar S; Lanzós A; Larsson E; Lawrence MS; Lee D; Lehmann KV; Li S; Li X; Lin Z; Liu EM; Lochovsky L; Lou S; Madsen T; Marchal K; Martincorena I; Martinez-Fundichely A; Maruvka YE; McGillivray PD; Meyerson W; Muiños F; Mularoni L; Nakagawa H; Nielsen MM; Paczkowska M; Park K; Park K; Pedersen JS; Pons T; Pulido-Tamayo S; Raphael BJ; Reimand J; Reyes-Salazar I; Reyna MA; Rheinbay E; Rubin MA; Rubio-Perez C; Sahinalp SC; Saksena G; Salichos L; Sander C; Schumacher SE; Shackleton M; Shapira O; Shen C; Shrestha R, 2020, 'Combined burden and functional impact tests for cancer driver discovery using DriverPower', Nature Communications, 11, http://dx.doi.org/10.1038/s41467-019-13929-1

Bhandari V; Li CH; Bristow RG; Boutros PC; Aaltonen LA; Abascal F; Abeshouse A; Aburatani H; Adams DJ; Agrawal N; Ahn KS; Ahn SM; Aikata H; Akbani R; Akdemir KC; Al-Ahmadie H; Al-Sedairy ST; Al-Shahrour F; Alawi M; Albert M; Aldape K; Alexandrov LB; Ally A; Alsop K; Alvarez EG; Amary F; Amin SB; Aminou B; Ammerpohl O; Anderson MJ; Ang Y; Antonello D; Anur P; Aparicio S; Appelbaum EL; Arai Y; Aretz A; Arihiro K; Ariizumi SI; Armenia J; Arnould L; Asa S; Assenov Y; Atwal G; Aukema S; Auman JT; Aure MRR; Awadalla P; Aymerich M; Bader GD; Baez-Ortega A; Bailey MH; Bailey PJ; Balasundaram M; Balu S; Bandopadhayay P; Banks RE; Barbi S; Barbour AP; Barenboim J; Barnholtz-Sloan J; Barr H; Barrera E; Bartlett J; Bartolome J; Bassi C; Bathe OF; Baumhoer D; Bavi P; Baylin SB; Bazant W; Beardsmore D; Beck TA; Behjati S; Behren A; Niu B; Bell C; Beltran S; Benz C; Berchuck A; Bergmann AK; Bergstrom EN; Berman BP; Berney DM; Bernhart SH; Beroukhim R; Berrios M; Bersani S; Bertl J; Betancourt M; Bhosle SG; Biankin AV; Bieg M; Bigner D; Binder H; Birney E; Birrer M; Biswas NK; Bjerkehagen B, 2020, 'Divergent mutational processes distinguish hypoxic and normoxic tumours', Nature Communications, 11, http://dx.doi.org/10.1038/s41467-019-14052-x

Sieverling L; Hong C; Koser SD; Ginsbach P; Kleinheinz K; Hutter B; Braun DM; Cortés-Ciriano I; Xi R; Kabbe R; Park PJ; Eils R; Schlesner M; Akdemir KC; Alvarez EG; Baez-Ortega A; Beroukhim R; Boutros PC; Bowtell DDL; Brors B; Burns KH; Campbell PJ; Chan K; Chen K; Dueso-Barroso A; Dunford AJ; Edwards PA; Estivill X; Etemadmoghadam D; Feuerbach L; Fink JL; Frenkel-Morgenstern M; Garsed DW; Gerstein M; Gordenin DA; Haan D; Haber JE; Hess JM; Imielinski M; Jones DTW; Ju YS; Kazanov MD; Klimczak LJ; Koh Y; Korbel JO; Kumar K; Lee EA; Lee JJK; Li Y; Lynch AG; Macintyre G; Markowetz F; Martincorena I; Martinez-Fundichely A; Meyerson M; Miyano S; Nakagawa H; Navarro FCP; Ossowski S; Pearson JV; Puiggròs M; Rippe K; Roberts ND; Roberts SA; Rodriguez-Martin B; Schumacher SE; Scully R; Shackleton M; Sidiropoulos N; Stewart C; Torrents D; Tubio JMC; Villasante I; Waddell N; Wala JA; Weischenfeldt J; Yang L; Yao X; Yoon SS; Zamora J; Zhang CZ; Aaltonen LA; Abascal F; Abeshouse A; Aburatani H; Adams DJ; Agrawal N; Ahn KS; Ahn SM; Aikata H; Akbani R; Akdemir KC; Al-Ahmadie H, 2020, 'Genomic footprints of activated telomere maintenance mechanisms in cancer', Nature Communications, 11, http://dx.doi.org/10.1038/s41467-019-13824-9

Zhang Y; Chen F; Fonseca NA; He Y; Fujita M; Nakagawa H; Zhang Z; Brazma A; Amin SB; Awadalla P; Bailey PJ; Brooks AN; Calabrese C; Chateigner A; Cortés-Ciriano I; Craft B; Craft D; Creighton CJ; Davidson NR; Demircioğlu D; Erkek S; Frenkel-Morgenstern M; Goldman MJ; Greger L; Göke J; Hoadley KA; Hou Y; Huska MR; Kahles A; Khurana E; Kilpinen H; Korbel JO; Lamaze FC; Lehmann KV; Li C; Li S; Li X; Li X; Liu D; Liu F; Liu X; Marin MG; Markowski J; Meyerson M; Nandi T; Nielsen MM; Ojesina AI; Ouellette BFF; Pan-Hammarström Q; Park PJ; Pedamallu CS; Pedersen JS; Perry MD; Rätsch G; Schwarz RF; Shiraishi Y; Siebert R; Soulette CM; Stark SG; Stegle O; Su H; Tan P; Teh BT; Urban L; Wang J; Waszak SM; Wu K; Xiang Q; Xiong H; Yakneen S; Yang H; Ye C; Yung CK; Zhang F; Zhang J; Zhang X; Zhang Z; Zheng L; Zhu J; Zhu S; Akdemir KC; Alvarez EG; Baez-Ortega A; Beroukhim R; Boutros PC; Bowtell DDL; Brors B; Burns KH; Campbell PJ; Chan K; Chen K; Dueso-Barroso A; Dunford AJ; Edwards PA; Estivill X; Etemadmoghadam D, 2020, 'High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations', Nature Communications, 11, http://dx.doi.org/10.1038/s41467-019-13885-w

Cmero M; Yuan K; Ong CS; Schröder J; Adams DJ; Anur P; Beroukhim R; Boutros PC; Bowtell DDL; Campbell PJ; Cao S; Christie EL; Cun Y; Dawson KJ; Demeulemeester J; Dentro SC; Deshwar AG; Donmez N; Drews RM; Eils R; Fan Y; Fittall MW; Garsed DW; Gerstung M; Getz G; Gonzalez S; Ha G; Haase K; Imielinski M; Jerman L; Ji Y; Jolly C; Kleinheinz K; Lee J; Lee-Six H; Leshchiner I; Livitz D; Malikic S; Martincorena I; Mitchell TJ; Morris QD; Mustonen V; Oesper L; Peifer M; Peto M; Raphael BJ; Rosebrock D; Rubanova Y; Sahinalp SC; Salcedo A; Schlesner M; Schumacher SE; Sengupta S; Shi R; Shin SJ; Spellman PT; Spiro O; Stein LD; Tarabichi M; Van Loo P; Vembu S; Vázquez-García I; Wang W; Wedge DC; Wheeler DA; Wintersinger JA; Yang TP; Yao X; Yu K; Zhu H; Corcoran NM; Papenfuss T; Hovens CM; Markowetz F; Macintyre G; Aaltonen LA; Abascal F; Abeshouse A; Aburatani H; Adams DJ; Agrawal N; Ahn KS; Ahn SM; Aikata H; Akbani R; Akdemir KC; Al-Ahmadie H; Al-Sedairy ST; Al-Shahrour F; Alawi M; Albert M; Aldape K; Alexandrov LB; Ally A; Alsop K; Alvarez EG; Amary F; Amin SB; Aminou B; Ammerpohl O, 2020, 'Inferring structural variant cancer cell fraction', Nature Communications, 11, http://dx.doi.org/10.1038/s41467-020-14351-8

Paczkowska M; Barenboim J; Sintupisut N; Fox NS; Zhu H; Abd-Rabbo D; Mee MW; Boutros PC; Abascal F; Amin SB; Bader GD; Beroukhim R; Bertl J; Boroevich KA; Brunak S; Campbell PJ; Carlevaro-Fita J; Chakravarty D; Chan CWY; Chen K; Choi JK; Deu-Pons J; Dhingra P; Diamanti K; Feuerbach L; Fink JL; Fonseca NA; Frigola J; Gambacorti-Passerini C; Garsed DW; Gerstein M; Getz G; Gonzalez-Perez A; Guo Q; Gut IG; Haan D; Hamilton MP; Haradhvala NJ; Harmanci AO; Helmy M; Herrmann C; Hess JM; Hobolth A; Hodzic E; Hong C; Hornshøj H; Isaev K; Izarzugaza JMG; Johnson R; Johnson TA; Juul M; Juul RI; Kahles A; Kahraman A; Kellis M; Khurana E; Kim J; Kim JK; Kim Y; Komorowski J; Korbel JO; Kumar S; Lanzós A; Lawrence MS; Lee D; Lehmann KV; Li S; Li X; Lin Z; Liu EM; Lochovsky L; Lou S; Madsen T; Marchal K; Martincorena I; Martinez-Fundichely A; Maruvka YE; McGillivray PD; Meyerson W; Muiños F; Mularoni L; Nakagawa H; Nielsen MM; Park K; Park K; Pedersen JS; Pich O; Pons T; Pulido-Tamayo S; Raphael BJ; Reyes-Salazar I; Reyna MA; Rheinbay E; Rubin MA; Rubio-Perez C; Sabarinathan R; Sahinalp SC; Saksena G; Salichos L; Sander C, 2020, 'Integrative pathway enrichment analysis of multivariate omics data', Nature Communications, 11, http://dx.doi.org/10.1038/s41467-019-13983-9

Reyna MA; Haan D; Paczkowska M; Verbeke LPC; Vazquez M; Kahraman A; Pulido-Tamayo S; Barenboim J; Wadi L; Dhingra P; Shrestha R; Getz G; Lawrence MS; Pedersen JS; Rubin MA; Wheeler DA; Brunak S; Izarzugaza JMG; Khurana E; Marchal K; von Mering C; Sahinalp SC; Valencia A; Abascal F; Amin SB; Bader GD; Bandopadhayay P; Beroukhim R; Bertl J; Boroevich KA; Busanovich J; Campbell PJ; Carlevaro-Fita J; Chakravarty D; Chan CWY; Chen K; Choi JK; Deu-Pons J; Diamanti K; Feuerbach L; Fink JL; Fonseca NA; Frigola J; Gambacorti-Passerini C; Garsed DW; Gerstein M; Guo Q; Gut IG; Hamilton MP; Haradhvala NJ; Harmanci AO; Helmy M; Herrmann C; Hess JM; Hobolth A; Hodzic E; Hong C; Hornshøj H; Isaev K; Johnson R; Johnson TA; Juul M; Juul RI; Kahles A; Kellis M; Kim J; Kim JK; Kim Y; Komorowski J; Korbel JO; Kumar S; Lanzós A; Larsson E; Lee D; Lehmann KV; Li S; Li X; Lin Z; Liu EM; Lochovsky L; Lou S; Madsen T; Martincorena I; Martinez-Fundichely A; Maruvka YE; McGillivray PD; Meyerson W; Muiños F; Mularoni L; Nakagawa H; Nielsen MM; Park K; Park K; Pons T; Reyes-Salazar I; Rheinbay E; Rubio-Perez C; Saksena G; Salichos L; Sander C, 2020, 'Pathway and network analysis of more than 2500 whole cancer genomes', Nature Communications, 11, http://dx.doi.org/10.1038/s41467-020-14367-0

Rubanova Y; Shi R; Harrigan CF; Li R; Wintersinger J; Sahin N; Deshwar AG; Dentro SC; Leshchiner I; Gerstung M; Jolly C; Haase K; Tarabichi M; Yu K; Gonzalez S; Macintyre G; Adams DJ; Anur P; Beroukhim R; Boutros PC; Bowtell DD; Campbell PJ; Cao S; Christie EL; Cmero M; Cun Y; Dawson KJ; Demeulemeester J; Donmez N; Drews RM; Eils R; Fan Y; Fittall M; Garsed DW; Getz G; Ha G; Imielinski M; Jerman L; Ji Y; Kleinheinz K; Lee J; Lee-Six H; Livitz DG; Malikic S; Markowetz F; Martincorena I; Mitchell TJ; Mustonen V; Oesper L; Peifer M; Peto M; Raphael BJ; Rosebrock D; Sahinalp SC; Salcedo A; Schlesner M; Schumacher S; Sengupta S; Shin SJ; Spiro O; Stein LD; Vázquez-García I; Vembu S; Wheeler DA; Yang TP; Yao X; Yuan K; Zhu H; Wang W; Morris QD; Spellman PT; Wedge DC; Van Loo P; Morris QD; Aaltonen LA; Abascal F; Abeshouse A; Aburatani H; Adams DJ; Agrawal N; Ahn KS; Ahn SM; Aikata H; Akbani R; Akdemir KC; Al-Ahmadie H; Al-Sedairy ST; Al-Shahrour F; Alawi M; Albert M; Aldape K; Alexandrov LB; Ally A; Alsop K; Alvarez EG; Amary F, 2020, 'Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig', Nature Communications, 11, http://dx.doi.org/10.1038/s41467-020-14352-7

Khuong-Quang DA; Brown LM; Wong M; Mayoh C; Sexton-Oates A; Kumar A; Pinese M; Nagabushan S; Lau L; Ludlow LE; Gifford AJ; Rodriguez M; Desai J; Fox SB; Haber M; Ziegler DS; Hansford JR; Marshall GM; Cowley MJ; Ekert PG; Wong-Erasmus M, 2020, 'Recurrent SPECC1L–NTRK fusions in pediatric sarcoma and brain tumors', Cold Spring Harbor Molecular Case Studies, 6, pp. mcs.a005710, http://dx.doi.org/10.1101/MCS.A005710

Bailey MH; Meyerson WU; Dursi LJ; Wang LB; Dong G; Liang WW; Weerasinghe A; Li S; Kelso S; Akbani R; Anur P; Buchanan A; Chiotti K; Covington K; Creason A; Ding L; Ellrott K; Fan Y; Foltz S; Getz G; Hale W; Haussler D; Hess JM; Hutter CM; Kandoth C; Kasaian K; Kasapi M; Larson D; Leshchiner I; Letaw J; Ma S; McLellan MD; Men Y; Mills GB; Niu B; Peto M; Radenbaugh A; Reynolds SM; Saksena G; Sofia H; Stewart C; Struck AJ; Stuart JM; Wang W; Weinstein JN; Wheeler DA; Wong CK; Xi L; Ye K; Bieg M; Boutros PC; Buchhalter I; Butler AP; Chen K; Chong Z; Drechsel O; Jonathan Dursi L; Eils R; Espiritu SMG; Fulton RS; Gao S; Gelpi JLL; Gonzalez S; Gut IG; Hach F; Heinold MC; Hinton J; Hu T; Huang V; Huang Y; Hutter B; Jones DR; Jung J; Jäger N; Kim HL; Kleinheinz K; Kumar S; Kumar Y; Lalansingh CM; Letunic I; Livitz D; Ma EZ; Maruvka YE; Mashl RJ; Menzies A; Milovanovic A; Nielsen MM; Ossowski S; Paramasivam N; Pedersen JS; Perry MD; Puiggròs M; Raine KM; Toon CCW; Biankin A; Merrett N; Pinese M; Lau L; Gill A; Chou A; Johns A, 2020, 'Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples', Nature Communications, 11, pp. 4748, http://dx.doi.org/10.1038/s41467-020-18151-y

Li CH; Prokopec SD; Sun RX; Yousif F; Schmitz N; Al-Shahrour F; Atwal G; Bailey PJ; Biankin AV; Boutros PC; Campbell PJ; Chang DK; Cooke SL; Deshpande V; Faltas BM; Faquin WC; Garraway L; Getz G; Grimmond SM; Haider S; Hoadley KA; Jiao W; Kaiser VB; Karlić R; Kato M; Kübler K; Lazar AJ; Louis DN; Margolin A; Martin S; Nahal-Bose HK; Nielsen GP; Nik-Zainal S; Omberg L; P’ng C; Perry MD; Polak P; Rheinbay E; Rubin MA; Semple CA; Sgroi DC; Shibata T; Siebert R; Smith J; Stein LD; Stobbe MD; Thai K; Wright DW; Wu CL; Yuan K; Zhang J; Aaltonen LA; Abascal F; Abeshouse A; Aburatani H; Adams DJ; Agrawal N; Ahn KS; Ahn SM; Aikata H; Akbani R; Akdemir KC; Al-Ahmadie H; Al-Sedairy ST; Alawi M; Albert M; Aldape K; Alexandrov LB; Ally A; Alsop K; Alvarez EG; Amary F; Amin SB; Aminou B; Ammerpohl O; Anderson MJ; Ang Y; Antonello D; Anur P; Aparicio S; Appelbaum EL; Arai Y; Aretz A; Arihiro K; Ariizumi SI; Armenia J; Arnould L; Asa S; Assenov Y; Aukema S; Auman JT; Aure MR; Awadalla P; Aymerich M; Bader GD; Baez-Ortega A; Pajic M; Merrett N; Pinese M; Lau L; Gill A; Toon CCW; Chou A; Johns A, 2020, 'Sex differences in oncogenic mutational processes', Nature Communications, 11, pp. 4330, http://dx.doi.org/10.1038/s41467-020-17359-2

Wong M; Mayoh C; Lau LMS; Khuong-Quang DA; Pinese M; Kumar A; Barahona P; Wilkie EE; Sullivan P; Bowen-James R; Syed M; Martincorena I; Abascal F; Sherstyuk A; Bolanos NA; Baber J; Priestley P; Dolman MEM; Fleuren EDG; Gauthier ME; Mould EVA; Gayevskiy V; Gifford AJ; Grebert-Wade D; Strong PA; Manouvrier E; Warby M; Thomas DM; Kirk J; Tucker K; O’Brien T; Alvaro F; McCowage GB; Dalla-Pozza L; Gottardo NG; Tapp H; Wood P; Khaw SL; Hansford JR; Moore AS; Norris MD; Trahair TN; Lock RB; Tyrrell V; Haber M; Marshall GM; Ziegler DS; Ekert PG; Cowley MJ; O'Brien T; Wong-Erasmus M, 2020, 'Whole genome, transcriptome and methylome profiling enhances actionable target discovery in high-risk pediatric cancer', Nature Medicine, 26, pp. 1742 - 1753, http://dx.doi.org/10.1038/s41591-020-1072-4

Xie J; Span M; van Maarseveen E; Langenhorst J; Boddy AV; Sia KCS; Sutton R; Venn N; Punt AM; Tyrrell V; Haber M; Trahair T; Lau L; Marshall GM; Lock RB, 2020, 'Optimization of a clofarabine-based drug combination regimen for the preclinical evaluation of pediatric acute lymphoblastic leukemia', Pediatric Blood and Cancer, 67, pp. e28133, http://dx.doi.org/10.1002/pbc.28133

Cortés-Ciriano I; Lee JJK; Xi R; Jain D; Jung YL; Yang L; Gordenin D; Klimczak LJ; Zhang CZ; Pellman DS; Akdemir KC; Alvarez EG; Baez-Ortega A; Beroukhim R; Boutros PC; Bowtell DDL; Brors B; Burns KH; Campbell PJ; Chan K; Chen K; Dueso-Barroso A; Dunford AJ; Edwards PA; Estivill X; Etemadmoghadam D; Feuerbach L; Fink JL; Frenkel-Morgenstern M; Garsed DW; Gerstein M; Haan D; Haber JE; Hess JM; Hutter B; Imielinski M; Jones DTW; Ju YS; Kazanov MD; Koh Y; Korbel JO; Kumar K; Lee EA; Li Y; Lynch AG; Macintyre G; Markowetz F; Martincorena I; Martinez-Fundichely A; Miyano S; Nakagawa H; Navarro FCP; Ossowski S; Pearson JV; Puiggròs M; Rippe K; Roberts ND; Roberts SA; Rodriguez-Martin B; Schumacher SE; Scully R; Shackleton M; Sidiropoulos N; Sieverling L; Stewart C; Torrents D; Tubio JMC; Villasante I; Waddell N; Wala JA; Weischenfeldt J; Yao X; Yoon SS; Zamora J; Park PJ; Aaltonen LA; Abascal F; Abeshouse A; Aburatani H; Adams DJ; Agrawal N; Ahn KS; Ahn SM; Aikata H; Akbani R; Akdemir KC; Al-Ahmadie H; Al-Sedairy ST; Al-Shahrour F; Alawi M; Albert M; Aldape K; Alexandrov LB; Ally A; Alsop K; Amary F, 2020, 'Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing', Nature Genetics, 52, pp. 331 - 341, http://dx.doi.org/10.1038/s41588-019-0576-7

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McGill BC; Wakefield CE; Hetherington K; Munro LJ; Warby M; Lau L; Tyrrell V; Ziegler DS; O’brien TA; Marshall GM; Malkin D; Hansford JR; Tucker KM; Vetsch J; O'Brien T, 2020, '“Balancing Expectations with Actual Realities”: Conversations with Clinicians and Scientists in the First Year of a High-Risk Childhood Cancer Precision Medicine Trial', Journal of Personalized Medicine, 10, pp. 9, http://dx.doi.org/10.3390/jpm10010009

Franshaw L; Tsoli M; Lau LMS; Ziegler DS, 2019, 'Translating palbociclib to the clinic for DIPG - What is truly achievable?', EBioMedicine, 45, pp. 22, http://dx.doi.org/10.1016/j.ebiom.2019.06.024

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Allanson BM; Weber MA; Jackett LA; Chan C; Lau L; Ziegler DS; Warby M; Mayoh C; Cowley MJ; Tucker KM; Long GV; Maher A; Anazodo A; Scolyer RA, 2018, 'Oral malignant gastrointestinal neuroectodermal tumour with junctional component mimicking mucosal melanoma', Pathology, 50, pp. 648 - 653, http://dx.doi.org/10.1016/j.pathol.2018.07.002

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Lee M; Teber ET; Holmes O; Nones K; Patch AM; Dagg RA; Lau LMS; Lee JH; Napier CE; Arthur JW; Grimmond SM; Hayward NK; Johansson PA; Mann GJ; Scolyer RA; Wilmott JS; Reddel RR; Pearson JV; Waddell N; Pickett HA, 2018, 'Telomere sequence content can be used to determine ALT activity in tumours', Nucleic Acids Research, 46, pp. 4903 - 4918, http://dx.doi.org/10.1093/nar/gky297

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Dagg RA; Pickett HA; Neumann AA; Napier CE; Henson JD; Teber ET; Arthur JW; Reynolds CP; Murray J; Haber M; Sobinoff AP; Lau LMS; Reddel RR, 2017, 'Extensive Proliferation of Human Cancer Cells with Ever-Shorter Telomeres', Cell Reports, 19, pp. 2544 - 2556, http://dx.doi.org/10.1016/j.celrep.2017.05.087

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Bradbury PM; Turner K; Mitchell C; Griffin KR; Middlemiss S; Lau L; Dagg R; Taran E; Cooper-White J; Fabry B; O'Neill GM, 2017, 'The focal adhesion targeting domain of p130Cas confers a mechanosensing function', Journal of Cell Science, 130, pp. 1263 - 1273, http://dx.doi.org/10.1242/jcs.192930

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Henson JD; Lau LM; Koch S; Martin La Rotta N; Dagg RA; Reddel RR, 2017, 'The C-Circle Assay for alternative-lengthening-of-telomeres activity', Methods, 114, pp. 74 - 84, http://dx.doi.org/10.1016/j.ymeth.2016.08.016

Small AG; Thwe LM; Byrne JA; Lau L; Chan A; Craig ME; Cowell CT; Garnett SP, 2015, 'Neuroblastoma, body mass index, and survival: a retrospective analysis', Medicine (United States), 94, http://dx.doi.org/10.1097/MD.0000000000000713

Saletta F; Seng M; Lau L, 2014, 'Advances in paediatric cancer treatment', Translational Pediatrics, 3, pp. 156 - 156, http://dx.doi.org/10.3978/j.issn.2224-4336.2014.02.01

Lee M; Hills M; Conomos D; Stutz MD; Dagg RA; Lau LMS; Reddel RR; Pickett HA, 2014, 'Telomere extension by telomerase and ALT generates variant repeats by mechanistically distinct processes', Nucleic Acids Research, 42, pp. 1733 - 1746, http://dx.doi.org/10.1093/nar/gkt1117

Farooqi AS; Dagg RA; Choi LMR; Shay JW; Reynolds CP; Lau LMS, 2014, 'Alternative lengthening of telomeres in neuroblastoma cell lines is associated with a lack of MYCN genomic amplification and with p53 pathway aberrations', Journal of Neuro-Oncology, 119, pp. 17 - 26, http://dx.doi.org/10.1007/s11060-014-1456-8

Lau LMS; Dagg RA; Henson JD; Au AYM; Royds JA; Reddel RR, 2013, 'Detection of alternative lengthening of telomeres by telomere quantitative PCR', Nucleic Acids Research, 41, pp. e34 - e34, http://dx.doi.org/10.1093/nar/gks781

Bower K; Napier CE; Cole SL; Dagg RA; Lau LMS; Duncan EL; Moy EL; Reddel RR, 2012, 'Loss of Wild-Type ATRX Expression in Somatic Cell Hybrids Segregates with Activation of Alternative Lengthening of Telomeres', PLoS ONE, 7, http://dx.doi.org/10.1371/journal.pone.0050062

Lau LMS; Wolter JK; Lau JTML; Cheng LS; Smith KM; Hansford LM; Zhang L; Baruchel S; Robinson F; Irwin MS, 2009, 'Cyclooxygenase inhibitors differentially modulate p73 isoforms in neuroblastoma', Oncogene, 28, pp. 2024 - 2033, http://dx.doi.org/10.1038/onc.2009.59

Lau LMS; Stuurman K; Weitzman S, 2008, 'Skeletal langerhans cell histiocytosis in children: Permanent consequences and health-related quality of life in long-term survivors', Pediatric Blood and Cancer, 50, pp. 607 - 612, http://dx.doi.org/10.1002/pbc.21322

Lau LMS; Nugent JK; Zhao X; Irwin MS, 2008, 'HDM2 antagonist Nutlin-3 disrupts p73-HDM2 binding and enhances p73 function', Oncogene, 27, pp. 997 - 1003, http://dx.doi.org/10.1038/sj.onc.1210707

Lau L; Hansford LM; Cheng LS; Hang M; Baruchel S; Kaplan DR; Irwin MS, 2007, 'Cyclooxygenase inhibitors modulate the p53/HDM2 pathway and enhance chemotherapy-induced apoptosis in neuroblastoma', Oncogene, 26, pp. 1920 - 1931, http://dx.doi.org/10.1038/sj.onc.1209981

Odame I; Li P; Lau L; Doda W; Noseworthy M; Babyn P; Weitzman S, 2006, 'Pulmonary Langerhans cell histiocytosis: A variable disease in childhood', Pediatric Blood and Cancer, 47, pp. 889 - 893, http://dx.doi.org/10.1002/pbc.20676

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