By Assistant Professor Loretta Lau

Preprints

Mayoh C; Gifford AJ; Terry R; Lau LM; Wong M; Rao P; Shai-Hee T; Saletta F; Khuong-Quang D-A; Qin V; Mateos M; Meyran D; Miller KE; Yuksel A; Mould EV; Bowen-James R; Govender D; Senapati A; Zhukova N; Omer N; Dholaria H; Alvaro F; Tapp H; Diamond Y; Pozza LD; Moore AS; Nicholls W; Gottardo NG; McCowage G; Hansford JR; Khaw S-L; Wood PJ; Catchpoole D; Cottrell CE; Mardis ER; Marshall GM; Tyrrell V; Haber M; Ziegler DS; Vittorio O; Trapani JA; Cowley MJ; Neeson PJ; Ekert PG, A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer, http://dx.doi.org/10.1101/2022.09.16.508179

Brown L; Tax G; Mateos PA; de Weck A; Foresto S; Robertson T; Jalud F; Ajuyah P; Barahona P; Mao J; Dolman ME; Wong M; Mayoh C; Cowley M; Lau L; Sadras T; Ekert P, A novel TRKB-activating internal tandem duplication characterizes a new mechanism of receptor tyrosine kinase activation, http://dx.doi.org/10.21203/rs.3.rs-5472548/v1

Brown LM; Mayoh C; Camper KA; Tax G; Mateos PA; Li W; El-Kamand S; Sullivan P; Bradley J; Thompson PI; Chen J; Sadras T; Salomon R; Wong M; Cowley MJ; de Weck A; Lau LMS; Manoharan N; Ekert PG, CBL mutations in pediatric solid and CNS tumors are a marker of receptor tyrosine kinase activation and a potential therapeutic target, http://dx.doi.org/10.64898/2025.12.02.691063

Fordham AM; Brown LM; Mayoh C; Salib A; Barger ZA; Wong M; Sian TCCLK; Xie J; Gunther K; Trebilcock P; Terry RL; Barahona P; Ajuyah P; Sherstyuk A; Avila A; Cadiz R; Perkins CM; Gifford AJ; Mao J; Zhao A; O’Regan LP; Gorgels D; Lau LM; Ziegler DS; Haber M; Tyrrell V; Lock RB; Cowley MJ; Nicholls W; Daly RJ; Ekert PG; Fleuren ED, Comprehensive multi-platform tyrosine kinase profiling reveals novel actionable FGFR aberrations across pediatric and AYA sarcomas, http://dx.doi.org/10.1101/2023.07.19.548825

Jung M; Poltavets V; Skhinas JN; Tax G; Kamili A; Xie A; Ghamrawi S; Graber P; Mao J; Wong-Erasmus M; Cui L; Kimpton K; Venkat P; Mayoh C; Fleuren EDG; Fordham AM; Barger Z; Grady J; Thomas DM; Du EY; Cowley MJ; Gifford AJ; Fletcher JI; Lau LMS; Dolman MEM; Gooding JJ; Kavallaris M, Engineered paediatric tumours retain maintains tumour genotype and phenotype for precision medicine, http://dx.doi.org/10.1101/2024.11.17.619539

Mayoh C; Barahona P; Lin A; Cui L; Ajuyah P; Altekoester A; Lau LM; Khuong-Quang D-A; Sullivan P; Senapati A; Nagabushan S; Sullivan A; Omer N; Moore AS; Nicholls W; Endersby R; Gottardo NG; McCowage G; Pozza LD; Hansford JR; Khaw S-L; Wood PJ; Trahair TN; Marshall GM; Ziegler DS; Tyrrell V; Haber M; Wong M; Ekert PG; Cowley MJ, Expanding the utility of transcriptome analysis for mutation detection in high-risk childhood precision oncology, http://dx.doi.org/10.1101/2025.06.25.661445

Sullivan AJ; Khuong-Quang D-A; Villani A; Wong-Erasmus M; Trinder S; Lau LMS; Barahona P; Altekoester A-K; Rumford M; Dias K; Mayoh C; Fuentes-Bolanos NA; Courtney EK; El-Kamand S; Cui L; Lin A; Davidson S; Yuki KE; Sanders N; Staunton J; Jessop S; Sriharan S; Alvaro F; Anazodo A; Bhatia K; Campbell M; Foresto S; Gottardo NG; Kirby M; Khaw SL; Manoharan N; McCowage G; Moore AS; Nicholls W; O’Connor M; Padhye B; Ryan AL; Super L; Wood PJ; Davies J; D’Arcy C; Gifford AJ; Rodriguez M; Tucker KM; Pinese M; Ekert PG; Haber M; Tyrrell V; Trahair TN; Marshall GM; Shlien A; Cowley MJ; Ziegler DS, High clinical utility of comprehensive multi-omic molecular profiling of rare and hard-to-diagnose pediatric tumors, http://dx.doi.org/10.21203/rs.3.rs-10108527/v1

Sullivan AJ; Khuong-Quang D-A; Villani A; Wong-Erasmus M; Trinder S; Lau LMS; Barahona P; Altekoester A-K; Rumford M; Dias K; Mayoh C; Fuentes-Bolanos NA; Courtney EK; El-Kamand S; Cui L; Lin A; Davidson S; Yuki KE; Sanders N; Staunton J; Jessop S; Sriharan S; Alvaro F; Anazodo A; Bhatia K; Campbell M; Foresto S; Gottardo NG; Kirby M; Khaw SL; Manoharan N; McCowage G; Moore AS; Nicholls W; O’Connor M; Padhye B; Ryan AL; Super L; Wood PJ; Davies J; D’Arcy C; Gifford AJ; Rodriguez M; Tucker KM; Pinese M; Ekert PG; Haber M; Tyrrell V; Trahair TN; Marshall GM; Shlien A; Cowley MJ; Ziegler DS, High clinical utility of comprehensive multi-omic molecular profiling of rare and hard-to-diagnose pediatric tumors, http://dx.doi.org/10.64898/2026.07.25.26358936

Fuentes-Bolanos NA; Courtney E; Mayoh C; Warby M; Lau LMS; Wong-Erasmus M; Khuong-Quang D-A; Barahona P; Padhye B; El-Kamand S; Nunag S; Ajuyah P; Sherstyuk A; Altekoester A-K; Sullivan A; Poplawski N; Kiraly-Borri C; O’Sullivan S; Marfan H; Alli R; Curnow L; Bhatia K; Anazodo A; Trahair TN; Mateos M; Hansford JR; Dholaria H; Josephi-Taylor S; Moore AS; Nicholls W; Gottardo NG; Downie P; Khaw S-L; Tapp H; McCowage G; Dalla-Pozza L; Alvaro F; Wood PJ; Tyrrell V; Haber M; Cowley MJ; Ekert PG; Marshall GM; Kirk J; Tucker K; Pinese M; Ziegler DS, Integrated germline and somatic molecular profiling to detect cancer predisposition has a high clinical impact in poor-prognosis paediatric cancer, http://dx.doi.org/10.1101/2024.08.08.24311493

Nawaz U; Deng N; Livson O; Mayoh C; Lau LMS; Reddel RR; Padhye B; Poulos RC, OnCorr: A pan-cancer mRNA-protein correlation tool for precision oncology, http://dx.doi.org/10.1101/2025.06.12.659426

Ziegler D; Lau L; Khuong-Quang D-A; Mayoh C; Wong M; Barahona P; Ajuyah P; Senapati A; Nagabushan S; Sherstyuk A; Altekoester A-K; Fuentes-Bolanos N; Yeung V; Sullivan A; Diamond Y; Omer N; Jessop S; Battaglia L; Zhukova N; Cui L; Lin A; Gifford A; Fleuren E; Dalla-Pozza L; Moore A; Khaw S; Eisenstat D; Gottardo N; Wood P; Tapp H; Alvaro F; McCowage G; Nicholls W; Hansford J; Manoharan N; Kotecha R; Mateos M; Lock R; Tyrrell V; Haber M; Trahair T; Cowley M; Ekert P; Marshall G, Precision-guided treatment improves outcomes for children with high-risk cancers, http://dx.doi.org/10.21203/rs.3.rs-3376668/v1

Mayoh C; Li W; Toumari M; Bazaz SR; Gerard A-L; Lowe A; Barahona P; Lau LM; Staunton J; Jacobson E; Nagabushan S; Manoharan N; Mitchell R; Ong F; Wong-Erasmus M; Ekert PG; Tyrrell V; Haber M; Ziegler DS; Cowley MJ; Mateos MK; Salomon R, Single-cell RNA-sequencing of cerebral spinal fluid identifies circulating tumour cells in children with brain cancer, http://dx.doi.org/10.64898/2025.12.18.694991

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