By Associate Professor David William Marshall Muller

Journal articles

Muller DWM; Gordon D; Topol EJ; Levy RJ; Golomb G, 1996, 'Sustained-release local hirulog therapy decreases early thrombosis but not neointimal thickening after arterial stenting', American Heart Journal, 131, pp. 211 - 218, http://dx.doi.org/10.1016/S0002-8703(96)90343-9

Beanlands RSB; Muzik O; Melon P; Sutor R; Sawada S; Muller D; Bondie D; Hutchins GD; Schwaiger M, 1995, 'Noninvasive quantification of regional myocardial flow reserve in patients with coronary atherosclerosis using nitrogen-13 ammonia positron emission tomography. Determination of extent of altered vascular reactivity', Journal of the American College of Cardiology, 26, pp. 1465 - 1475, http://dx.doi.org/10.1016/0735-1097(95)00359-2

Cohen JL; Chan KL; Jaarsma W; Bach DS; Muller DWM; Starling MR; Armstrong WF, 1995, 'Arbutamine echocardiography: Efficacy and safety of a new pharmacologic stress agent to induce myocardial ischemia and detect coronary artery disease', Journal of the American College of Cardiology, 26, pp. 1168 - 1175, http://dx.doi.org/10.1016/0735-1097(95)00296-0

Dennis CA; Pool PE; Perrins EJ; Mohiuddin SM; Sklar J; Kostuk WJ; Muller DWM; Starling MR, 1995, 'Stress testing with closed-loop arbutamine as an alternative to exercise', Journal of the American College of Cardiology, 26, pp. 1151 - 1158, http://dx.doi.org/10.1016/0735-1097(95)00297-9

Stephan WJ; Bates ER; Garratt KN; Hinohara T; Muller DWM, 1995, 'Directional atherectomy of coronary and saphenous vein graft ostial stenoses', The American Journal of Cardiology, 75, pp. 1015 - 1018, http://dx.doi.org/10.1016/S0002-9149(99)80715-2

Bach DS; Muller DWM; Cheirif J; Armstrong WF, 1995, 'Regional heterogeneity on myocardial contrast echocardiography without severe obstructive coronary artery disease', The American Journal of Cardiology, 75, pp. 982 - 986, http://dx.doi.org/10.1016/S0002-9149(99)80708-5

HOLMES DR; TOPOL EJ; CALIFF RM; BERDAN LG; LEYA F; BERGER PB; WHITLOW PL; SAFIAN RD; ADELMAN AG; KELLETT MA; TALLEY JD; SHANI J; GOTTLIEB RS; PINKERTON CA; LEE KL; KEELER GP; ELLIS SG; FRANCO I; DEBOWEY D; LINCOFF M; KEREIAKES D; ABBOTTSMITH C; KENT K; LEON M; PICHARD A; SATLER L; POPMA J; HINOHARA T; KOSINSKI E; SIMONTON C; BERSIN RM; CEDARHOLM J; WILSON B; MCKEEVER LS; MARTIN F; CHAPEKIS A; GEORGE BS; COWLEY M; PINKERTON C; PETERS T; COHEN M; JACOBS A; FAXON DP; LEVINE G; KELLETT M; KING S; MASDEN R; MOONEY M; WHITE CJ; HOFLING B; WILLIAMS D; TALLEY D; WHITE H; BRINKER J; STEWART DK; CHAMBERS J; AU P; PALACIOS I; KUNTZ R; SAFIAN R; IVANHOE R; PUEL J; RAYBUCK B; BONAN R; PEARSON C; LAIRD JR; BURWELL L; CARNEY RJ; BELLINGER R; RICCI D; SPOKOJNY A; MARTYAK TE; COHEN E; ADELMAN A; LEWIS S; WEBB J; TRABOULSI D; REEN B; NIESS G; SLATER J; MARQUIS JF; BUSH HS; MOSES JW; HEUSER R; AYRES M; APFELBAUM MA; BLEICH S; ROUBIN G; STEIN R; HARTMAN CW; DENARDO R; LINDSEY D; CORIN W; UNTERECKER B; STILLABOWER M; MICK M; SHARMA S; COHEN H; BARBEAU G; GRIFFIN J; ARNOLD A; CALIFF R, 1995, 'A MULTICENTER, RANDOMIZED TRIAL OF CORONARY ANGIOPLASTY VERSUS DIRECTIONAL ATHERECTOMY FOR PATIENTS WITH SAPHENOUS-VEIN BYPASS GRAFT LESIONS', CIRCULATION, 91, pp. 1966 - 1974, http://dx.doi.org/10.1161/01.CIR.91.7.1966

Grossman M; Rader DJ; Muller DWM; Kolansky DM; Kozarsky K; Clark BJ; Stein EA; Lupien PJ; Brewer HB; Raper SE; Wilson JM, 1995, 'A pilot study of ex vivo gene therapy for homozygous familial hypercholesterolaemia', Nature Medicine, 1, pp. 1148 - 1154, http://dx.doi.org/10.1038/nm1195-1148

Pompili VJ; Gordon D; San H; Yang Z; Muller DWM; Nabel GJ; Nabel EG, 1995, 'Expression and function of a recombinant PDGF B gene in porcine arteries', Arteriosclerosis, Thrombosis, and Vascular Biology, 15, pp. 2254 - 2264, http://dx.doi.org/10.1161/01.ATV.15.12.2254

Bach DS; Armstrong WF; Collins T; Muller DWM; Ramee SR; Bruns DE; Cheirif J, 1995, 'Intracoronary and aortic root myocardial contrast echocardiography: The effect of route, dose, and pharmacologic coronary vasodilation', Journal of the American Society of Echocardiography, 8, pp. 719 - 727, http://dx.doi.org/10.1016/S0894-7317(05)80387-6

Muller DW, 1994, 'Gene therapy for the management of cardiovascular disease.', The Journal of invasive cardiology, 6, pp. 89 - 96

Rosenschein U; Ellis SG; Haudenschild CC; Yakubov SJ; Muller DWM; Dick RJ; Topol EJ, 1994, 'Comparison of histopathologic coronary lesions obtained from directional atherectomy in stable angina versus acute coronary syndromes', The American Journal of Cardiology, 73, pp. 508 - 510, http://dx.doi.org/10.1016/0002-9149(94)90683-1

Chen SJ; Wilson JM; Muller DWM, 1994, 'Adenovirus-mediated gene transfer of soluble vascular cell adhesion molecule to porcine interposition vein grafts', Circulation, 89, pp. 1922 - 1928, http://dx.doi.org/10.1161/01.CIR.89.5.1922

Muller DWM; Gordon D; San H; Yang Z; Pompili VJ; Nabel GJ; Nabel EG, 1994, 'Catheter-mediated pulmonary vascular gene transfer and expression', Circulation Research, 75, pp. 1039 - 1049, http://dx.doi.org/10.1161/01.RES.75.6.1039

Maclsaac AI; Ellis SG; Muller DW; Topol EJ; Whitlow PL, 1994, 'Comparison of three coronary stents: Clinical and angiographic outcome after elective placement in 134 consecutive patients', Catheterization and Cardiovascular Diagnosis, 33, pp. 199 - 204, http://dx.doi.org/10.1002/ccd.1810330302

Bach DS; Muller DWM; Gros BJ; Armstrong WF, 1994, 'False positive dobutamine stress echocardiograms: Characterization of clinical, echocardiographic and angiographic findings', Journal of the American College of Cardiology, 24, pp. 928 - 933, http://dx.doi.org/10.1016/0735-1097(94)90851-6

Muller DWM, 1994, 'Gene therapy for cardiovascular disease', Heart, 72, pp. 309 - 312, http://dx.doi.org/10.1136/hrt.72.4.309

Nabel EG; Yang Z; Muller D; Chang AE; Gao X; Huang L; Cho KJ; Nabel GJ, 1994, 'Safety and toxicity of catheter gene delivery to the pulmonary vasculature in a patient with metastatic melanoma', Human Gene Therapy, 5, pp. 1089 - 1094

Muller DWM; Golomb G; Gordon D; Levy RJ, 1994, 'Site-specific dexamethasone delivery for the prevention of neointimal thickening after vascular stent implantation', Coronary Artery Disease, 5, pp. 435 - 442, http://dx.doi.org/10.1097/00019501-199405000-00010

Grossman M; Raper SE; Kozarsky K; Stein EA; Engelhardt JF; Muller D; Lupien PJ; Wilson JM, 1994, 'Successful ex vivo gene therapy directed to liver in a patient with familial hypercholesterolaemia', Nature Genetics, 6, pp. 335 - 341, http://dx.doi.org/10.1038/ng0494-335

Nath FC; Muller DWM; Rosenschein U; Ellis SG; Topol EJ, 1993, 'Heparin monitoring during coronary intervention: Activated clotting time versus activated partial thromboplastin time', Canadian Journal of Cardiology, 9, pp. 797 - 801

Lincoff AM; Topol EJ; Chapekis AT; George BS; Candela RJ; Muller DWM; Zimmerman CA; Ellis SG, 1993, 'Intracoronary stenting compared with conventional therapy for abrupt vessel closure complicating coronary angioplasty. A matched case-control study', Journal of the American College of Cardiology, 21, pp. 866 - 875, http://dx.doi.org/10.1016/0735-1097(93)90341-W

Nath FC; Muller DWM; Ellis SG; Rosenschein U; Chapekis A; Quain L; Zimmerman C; Topol EJ, 1993, 'Thrombosis of a flexible coil coronary stent: Frequency, predictors and clinical outcome', Journal of the American College of Cardiology, 21, pp. 622 - 627, http://dx.doi.org/10.1016/0735-1097(93)90093-G

Laubenbacher C; Rothley J; Sitomer J; Beanlands R; Sawada S; Sutor R; Muller D; Schwaiger M, 1993, 'An automated analysis program for the evaluation of cardiac PET studies: Initial results in the detection and localization of coronary artery disease using nitrogen-13-ammonia', Journal of Nuclear Medicine, 34, pp. 968 - 978

Topol EJ; Ellis SG; Cosgrove DM; Bates ER; Muller DWM; Schork NJ; Schork MA; Loop FD, 1993, 'Analysis of coronary angioplasty practice in the United States with an insurance-claims data base', Circulation, 87, pp. 1489 - 1497

BEEKMAN RH; MULLER DWM; REYNOLDS PI; MOOREHEAD C; HEIDELBERGER K; LUPINETTI FM, 1993, 'Balloon‐Expandable Stent Treatment of Experimental Coarctation of the Aorta: Early Hemodynamic and Pathological Evaluation', Journal of Interventional Cardiology, 6, pp. 113 - 123, http://dx.doi.org/10.1111/j.1540-8183.1993.tb00843.x

Ellis SG; Tcheng JE; Navetta FI; Muller DWM; Weisman HF; Smith C; Anderson KM; Califf RM; Topol EJ, 1993, 'Safety and antiplatelet effect of murine monoclonal antibody 7E3 Fab directed against platelet glycoprotein IIb/IIIa in patients undergoing elective coronary angioplasty', Coronary Artery Disease, 4, pp. 167 - 175, http://dx.doi.org/10.1097/00019501-199302000-00007

Muller DWM; Topol EJ, 1992, 'Thrombolytic therapy: Adjuvant mechanical intervention for acute myocardial infarction', The American Journal of Cardiology, 69, http://dx.doi.org/10.1016/0002-9149(92)91172-Z

Ellis SG; Muller DWM, 1992, 'Arterial injury and the enigma of coronary restenosis', Journal of the American College of Cardiology, 19, pp. 275 - 277, http://dx.doi.org/10.1016/0735-1097(92)90477-5

Muller DWM; Ellis SG; Topol EJ, 1992, 'Erratum: Experimental models of coronary artery restenosis (J Am Coll Cardiol (1992) 19 (418-32))', Journal of the American College of Cardiology, 19, pp. 1678

Muller DWM; Ellis SG; Topol EJ, 1992, 'Experimental models of coronary artery restenosis', Journal of the American College of Cardiology, 19, pp. 418 - 432, http://dx.doi.org/10.1016/0735-1097(92)90500-M

Muller DWM; Topol EJ; Abrams GD; Gallagher KP; Ellis SG, 1992, 'Intramural methotrexate therapy for the prevention of neointimal thickening after ballon angioplasty', Journal of the American College of Cardiology, 20, pp. 460 - 466, http://dx.doi.org/10.1016/0735-1097(92)90118-7

Muller DWM; Shamir KJ; Ellis SG; Topol EJ, 1992, 'Peripheral vascular complications after conventional and complex percutaneous coronary interventional procedures', The American Journal of Cardiology, 69, pp. 63 - 68, http://dx.doi.org/10.1016/0002-9149(92)90677-Q

Williaon BD; Muller DWM; Topol EJ, 1992, 'Should Older Patients with Acute Myocardial Infarction Receive Thrombolytic Therapy?', Drugs & Aging, 2, pp. 461 - 468, http://dx.doi.org/10.2165/00002512-199202060-00002

Dick RJ; Popma JJ; Muller DWM; Burek KA; Topol EJ, 1991, 'In-hospital costs associated with new percutaneous coronary devices', The American Journal of Cardiology, 68, pp. 879 - 885, http://dx.doi.org/10.1016/0002-9149(91)90403-8

Anan'eva NA; Iampol'skaia IA; Müller D; Müller D; Voǐvod U; Klein E, 1991, 'Use of a unified approach to the study of health status of l3-l5 years old schoolchildren in the USSR and Democratic Republic of Germany', Gigiena i sanitariia, pp. 68 - 70

Ver Lee PN; Muller DWM; Popma JJ; Ellis SG; Topol EJ, 1991, 'A comparison of clinical and quantitative angiographic outcomes of coronary stenting in elective and emergency settings: A single center experience', Coronary Artery Disease, 2, pp. 945 - 951

Nabel EG; Topol EJ; Galeana A; Ellis SG; Bates ER; Werns SW; Walton JA; Muller DW; Schwaiger M; Pitt B, 1991, 'A randomized placebo-controlled trial of combined early intravenous captopril and recombinant tissue-type plasminogen activator therapy in acute myocardial infarction', Journal of the American College of Cardiology, 17, pp. 467 - 473, http://dx.doi.org/10.1016/S0735-1097(10)80117-2

Muller DWM; Ellis SG; Topol EJ, 1991, 'Colchicine and antineoplastic therapy for the prevention of restenosis after percutaneous coronary interventions', Journal of the American College of Cardiology, 17, pp. 126 - 131, http://dx.doi.org/10.1016/0735-1097(91)90948-9

Morris JA; Muller DWM; Topol EJ, 1991, 'Combination thrombolytic therapy: A comparison of simultaneous and sequential regimens of tissue plasminogen activator and urokinase', American Heart Journal, 122, pp. 375 - 380, http://dx.doi.org/10.1016/0002-8703(91)90988-T

Muller DWM; Topol EJ; Ellis SG; Woodlief LH; Sigmon KN; Kereiakes DJ; George BS; Worley SJ; Samaha JK; Phillips H; Califf RM, 1991, 'Determinants of the need for early acute intervention in patients treated conservatively after thrombolytic therapy for acute myocardial infarction', Journal of the American College of Cardiology, 18, pp. 1594 - 1601, http://dx.doi.org/10.1016/0735-1097(91)90490-Z

Dick RJL; Haudenschild CC; Popma JJ; Ellis SG; Muller DW; Topol EJ, 1991, 'Directional atherectomy for total coronary occlusions', Coronary Artery Disease, 2, pp. 189 - 199, http://dx.doi.org/10.1097/00019501-199104000-00010

Rosenfeldt FL; Muller D; Harper R; Shardey GC; Broughton A, 1991, 'Early and late results of surgery for Wolff‐Parkinson‐White syndrome', Australian and New Zealand Journal of Medicine, 21, pp. 325 - 329, http://dx.doi.org/10.1111/j.1445-5994.1991.tb04698.x

Muller DWM; Topol EJ, 1991, 'Implantable devices in the coronary artery from metal to genes', Trends in Cardiovascular Medicine, 1, pp. 225 - 232, http://dx.doi.org/10.1016/1050-1738(91)90026-B

Muller DWM; Topol EJ; Ellis SG; Sigmon KN; Lee K; Califf RM, 1991, 'Multivessel coronary artery disease: A key predictor of short-term prognosis after reperfusion therapy for acute myocardial infarction', American Heart Journal, 121, pp. 1042 - 1049, http://dx.doi.org/10.1016/0002-8703(91)90661-Z

Muller DWM; Topol EJ, 1990, 'Selection of patients with acute myocardial infarction for thrombolytic therapy', Annals of Internal Medicine, 113, pp. 949 - 960

Muller DWM; Ellis SG; Debowey DL; Topol EJ, 1990, 'Quantitative angiographic comparison of the immediate success of coronary angioplasty, coronary atherectomy and endoluminal stenting', The American Journal of Cardiology, 66, pp. 938 - 942, http://dx.doi.org/10.1016/0002-9149(90)90929-U

Muller DWM; Topol EJ; George BS; Kereiakes DJ; Aronson LG; Lee KL; Abbottsmith CW; Ellis SG; Califf RM, 1990, 'Two-year outcome after angiographically documented myocardial reperfusion for acute coronary occlusion', The American Journal of Cardiology, 66, pp. 796 - 801, http://dx.doi.org/10.1016/0002-9149(90)90354-4

Ellis SG; Muller DW; Topol EJ, 1990, 'Possible survival benefit from concomitant beta-but not calcium-antagonist therapy during reperfusion for acute myocardial infarction', The American Journal of Cardiology, 66, pp. 125 - 128, http://dx.doi.org/10.1016/0002-9149(90)90574-K

Muller DW; Topol EJ, 1990, 'Protected coronary angioplasty: minimizing the hazards of high risk coronary interventions.', The Journal of invasive cardiology, 2, pp. 103 - 107

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