By Associate Professor Dorit Samocha-Bonet

Journal articles

Wark G; Kaakoush NO; Samocha-Bonet D; Ghaly S; Danta M, 2024, 'P1233 Serum insulin is associated with c-reactive protein and gut microbial diversity in inflammatory bowel disease', Journal of Crohn's and Colitis, 18, pp. i2183 - i2183, http://dx.doi.org/10.1093/ecco-jcc/jjad212.1363

Katsoudas N; Tavakoli P; Wu N; Shapiro A; Leach ST; Williams A-J; Paramsothy R; Ghaly S; Connor SJ; Samocha-Bonet D; Lambert K; Hold GL, 2024, 'Dietary Emulsifier Exposure in People With Inflammatory Bowel Disease Compared With Healthy Controls: Is There a Cause for Concern?', Inflamm Bowel Dis, http://dx.doi.org/10.1093/ibd/izad318

Shalaby N; Samocha-Bonet D; Kaakoush NO; Danta M, 2023, 'The Role of the Gastrointestinal Microbiome in Liver Disease', Pathogens, 12, http://dx.doi.org/10.3390/pathogens12091087

Koay YC; Coster ACF; Chen DL; Milner B; Batarseh A; O’Sullivan JF; Greenfield JR; Samocha-Bonet D, 2022, 'Metabolomics and Lipidomics Signatures of Insulin Resistance and Abdominal Fat Depots in People Living with Obesity', Metabolites, 12, pp. 1272, http://dx.doi.org/10.3390/metabo12121272

Watt KI; Henstridge DC; Ziemann M; Sim CB; Montgomery MK; Samocha-Bonet D; Parker BL; Dodd GT; Bond ST; Salmi TM; Lee RS; Thomson RE; Hagg A; Davey JR; Qian H; Koopman R; El-Osta A; Greenfield JR; Watt MJ; Febbraio MA; Drew BG; Cox AG; Porrello ER; Harvey KF; Gregorevic P, 2021, 'Yap regulates skeletal muscle fatty acid oxidation and adiposity in metabolic disease', Nature Communications, 12, http://dx.doi.org/10.1038/s41467-021-23240-7

Samocha-Bonet D; Wu B; Ryugo DK, 2021, 'Diabetes mellitus and hearing loss: A review', Ageing Research Reviews, 71, pp. 101423, http://dx.doi.org/10.1016/j.arr.2021.101423

Snaith JR; Samocha-Bonet D; Evans J; Liu Z; Kowalski G; Bruce C; Holmes-Walker DJ; Greenfield JR, 2021, 'Insulin resistance in type 1 diabetes managed with metformin (INTIMET): Study protocol of a double-blind placebo-controlled, randomised trial', Diabetic Medicine, 38, http://dx.doi.org/10.1111/dme.14564

Lambert K; Pappas D; Miglioretto C; Javadpour A; Reveley H; Frank L; Grimm MC; Samocha-Bonet D; Hold GL, 2021, 'Systematic review with meta-analysis: dietary intake in adults with inflammatory bowel disease', Alimentary Pharmacology and Therapeutics, 54, pp. 742 - 754, http://dx.doi.org/10.1111/apt.16549

Bishay RH; Tonks KT; George J; Samocha-Bonet D; Meyerowitz-Katz G; Chisholm DJ; James DE; Greenfield JR, 2021, 'Plasma Bile Acids More Closely Align with Insulin Resistance, Visceral and Hepatic Adiposity Than Total Adiposity', Journal of Clinical Endocrinology and Metabolism, 106, pp. E1131 - E1139, http://dx.doi.org/10.1210/clinem/dgaa940

Williams AJ; Paramsothy R; Wu N; Ghaly S; Leach S; Paramsothy S; Corte C; O'Brien C; Burke C; Wark G; Samocha-Bonet D; Lambert K; Ahlenstiel G; Wasinger V; Dutt S; Pavli P; Grimm M; Lemberg D; Connor S; Leong R; Hold G, 2021, 'Australia IBD Microbiome (AIM) Study: Protocol for a multicentre longitudinal prospective cohort study', BMJ Open, 11, http://dx.doi.org/10.1136/bmjopen-2020-042493

Wark G; Samocha-Bonet D; Ghaly S; Danta M, 2021, 'The role of diet in the pathogenesis and management of inflammatory bowel disease: A review', Nutrients, 13, pp. 1 - 26, http://dx.doi.org/10.3390/nu13010135

Htet TD; Godneva A; Liu Z; Chalmers E; Kolobkov D; Snaith JR; Richens R; Toth K; Danta M; Hng TM; Elinav E; Segal E; Greenfield JR; Samocha-Bonet D, 2020, 'Rationale and design of a randomised controlled trial testing the effect of personalised diet in individuals with pre-diabetes or type 2 diabetes mellitus treated with metformin', BMJ Open, 10, pp. e037859, http://dx.doi.org/10.1136/bmjopen-2020-037859

Wali JA; Koay YC; Chami J; Wood C; Corcilius L; Payne RJ; Rodionov RN; Birkenfeld AL; Samocha-Bonet D; Simpson SJ; O’Sullivan JF, 2020, 'Nutritional and metabolic regulation of the metabolite dimethylguanidino valeric acid: an early marker of cardiometabolic disease', American Journal of Physiology - Endocrinology and Metabolism, 319, pp. E509 - E518, http://dx.doi.org/10.1152/ajpendo.00207.2020

Chalmers E; Samocha-Bonet D, 2020, 'The effect of body acid–base state and manipulations on body glucose regulation in human', European Journal of Clinical Nutrition, 74, pp. 20 - 26, http://dx.doi.org/10.1038/s41430-020-0692-6

Snaith JR; Samocha-Bonet D; Holmes-Walker DJ; Greenfield JR, 2020, 'MON-LB113 Insulin Resistance in Type 1 Diabetes Managed With Metformin (INTIMET): Rationale and Study Design of a Randomised Placebo-Controlled Trial', Journal of the Endocrine Society, 4, http://dx.doi.org/10.1210/jendso/bvaa046.2038

Harari A; Coster ACF; Jenkins A; Xu A; Greenfield JR; Harats D; Shaish A; Samocha-Bonet D, 2020, 'Obesity and Insulin Resistance Are Inversely Associated with Serum and Adipose Tissue Carotenoid Concentrations in Adults', Journal of Nutrition, 150, pp. 38 - 46, http://dx.doi.org/10.1093/jn/nxz184

Montgomery MK; Bayliss J; Devereux C; Bezawork-Geleta A; Roberts D; Huang C; Schittenhelm RB; Ryan A; Townley SL; Selth LA; Biden TJ; Steinberg GR; Samocha-Bonet D; Meex RCR; Watt MJ, 2020, 'SMOC1 is a glucose-responsive hepatokine and therapeutic target for glycemic control', Science Translational Medicine, 12, http://dx.doi.org/10.1126/SCITRANSLMED.AAZ8048

Milder TY; Stocker SL; Samocha-Bonet D; Day RO; Greenfield JR, 2019, 'Sodium-glucose cotransporter 2 inhibitors for type 2 diabetes—cardiovascular and renal benefits in patients with chronic kidney disease', European Journal of Clinical Pharmacology, 75, pp. 1481 - 1490, http://dx.doi.org/10.1007/s00228-019-02732-y

Tang A; Coster ACF; Tonks KT; Heilbronn LK; Pocock N; Purtell L; Govendir M; Blythe J; Zhang J; Xu A; Chisholm DJ; Johnson NA; Greenfield JR; Samocha-Bonet D, 2019, 'Longitudinal changes in insulin resistance in normal weight, overweight and obese individuals', Journal of Clinical Medicine, 8, pp. 623, http://dx.doi.org/10.3390/jcm8050623

Milder TY; Stocker SL; Shaheed CA; McGrath-Cadell L; Samocha-Bonet D; Greenfield JR; Day RO, 2019, 'Combination Therapy with an SGLT2 Inhibitor as Initial Treatment for Type 2 Diabetes: A Systematic Review and Meta-Analysis', JOURNAL OF CLINICAL MEDICINE, 8, http://dx.doi.org/10.3390/jcm8010045

Bishay RH; Tonks KT; George J; Samocha-Bonet D; Chisholm DJ; James DE; Greenfield JR, 2019, 'Circulating bile acids are associated with insulin resistance and visceral and liver fat in human subjects', Obesity Research & Clinical Practice, 13, pp. 28 - 29, http://dx.doi.org/10.1016/j.orcp.2016.10.030

Tang A; Tonks KT; Heilbronn LK; Pocock NA; Campbell LV; James DE; Chisholm DJ; Greenfield JR; Samocha-Bonet D, 2019, 'Insulin-sensitive overweight/obese individuals remain as insulin sensitive and normotensive as lean subjects over 6 years', Obesity Research & Clinical Practice, 13, pp. 35 - 35, http://dx.doi.org/10.1016/j.orcp.2016.10.042

Koay YC; Yang P; Chen D; Jenkins AB; Greenfield J; O'Sullvan JF; Samocha-Bonet D, 2019, 'Novel circulating biomarkers identify insulin resistance phenotypes in obesity', Obesity Research & Clinical Practice, 13, pp. 267 - 268, http://dx.doi.org/10.1016/j.orcp.2018.11.092

Samocha-Bonet D, 2019, 'The diverse obesity phenotypes – Implication for treatment', Obesity Research & Clinical Practice, 13, pp. 243 - 243, http://dx.doi.org/10.1016/j.orcp.2018.11.021

Elshorbagy AK; Samocha-Bonet D; Jernerén F; Turner C; Refsum H; Heilbronn LK, 2018, 'Food Overconsumption in Healthy Adults Triggers Early and Sustained Increases in Serum Branched-Chain Amino Acids and Changes in Cysteine Linked to Fat Gain', Journal of Nutrition, 148, pp. 1073 - 1080, http://dx.doi.org/10.1093/jn/nxy062

Du YT; Piscitelli D; Ahmad S; Trahair LG; Greenfield JR; Samocha-Bonet D; Rayner CK; Horowitz M; Jones KL, 2018, 'Effects of glutamine on gastric emptying of lowand high-nutrient drinks in healthy young subjects—impact on glycaemia', Nutrients, 10, http://dx.doi.org/10.3390/nu10060739

Samocha-Bonet D; Debs S; Greenfield JR, 2018, 'Prevention and Treatment of Type 2 Diabetes: A Pathophysiological-Based Approach', Trends in Endocrinology and Metabolism, 29, pp. 370 - 379, http://dx.doi.org/10.1016/j.tem.2018.03.014

Ma C; Tonks KT; Center JR; Samocha-Bonet D; Greenfield JR, 2018, 'Complex interplay among adiposity, insulin resistance and bone health', Clinical Obesity, 8, pp. 131 - 139, http://dx.doi.org/10.1111/cob.12240

Fazakerley DJ; Chaudhuri R; Yang P; Maghzal GJ; Thomas KC; Krycer JR; Humphrey SJ; Parker BL; Fisher-Wellman KH; Meoli CC; Hoffman NJ; Diskin C; Burchfield JG; Cowley MJ; Kaplan W; Modrusan Z; Kolumam G; Yang JYH; Chen DL; Samocha-Bonet D; Greenfield JR; Hoehn KL; Stocker R; James DE; Chen D; Southwell Keely P, 2018, 'Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance', eLife, 7, pp. e32111, http://dx.doi.org/10.7554/eLife.32111

Kozan P; Blythe JC; Greenfield JR; Samocha-Bonet D, 2017, 'The effect of buffering high acid load meal with sodium bicarbonate on postprandial glucose metabolism in humans—A randomized placebo-controlled study', Nutrients, 9, pp. 861, http://dx.doi.org/10.3390/nu9080861

Tonks KT; White CP; Center JR; Samocha-Bonet D; Greenfield JR, 2017, 'Bone turnover is suppressed in insulin resistance, independent of adiposity', Journal of Clinical Endocrinology and Metabolism, 102, pp. 1112 - 1121, http://dx.doi.org/10.1210/jc.2016-3282

Mackie GM; Samocha-Bonet D; Tam CS, 2017, 'Does weight cycling promote obesity and metabolic risk factors?', Obesity Research and Clinical Practice, 11, pp. 131 - 139, http://dx.doi.org/10.1016/j.orcp.2016.10.284

Chen DLT; Brown R; Liess C; Poljak A; Xu A; Zhang J; Trenell M; Jenkins A; Chisholm D; Samocha-Bonet D; Macefield VG; Greenfield JR; Chen D; Milliken S; Goodnow C, 2017, 'Muscle sympathetic nerve activity is associated with liver insulin sensitivity in obese non-diabetic men', Frontiers in Physiology, 8, pp. 101, http://dx.doi.org/10.3389/fphys.2017.00101

Tam CS; Chaudhuri R; Hutchison AT; Samocha-Bonet D; Heilbronn LK, 2017, 'Skeletal muscle extracellular matrix remodeling after short-term overfeeding in healthy humans', Metabolism: Clinical and Experimental, 67, pp. 26 - 30, http://dx.doi.org/10.1016/j.metabol.2016.10.009

Radhakutty A; Mangelsdorf BL; Drake SM; Samocha-Bonet D; Heilbronn LK; Smith MD; Thompson CH; Burt MG, 2016, 'Effects of prednisolone on energy and fat metabolism in patients with rheumatoid arthritis: tissue-specific insulin resistance with commonly used prednisolone doses', Clinical Endocrinology, 85, pp. 741 - 747, http://dx.doi.org/10.1111/cen.13138

He J; Chen DL; Samocha-Bonet D; Gillinder KR; Barclay JL; Magor GW; Perkins AC; Greenfield JR; Yang G; Whitehead JP, 2016, 'Fibroblast growth factor-1 (FGF-1) promotes adipogenesis by downregulation of carboxypeptidase A4 (CPA4)–a negative regulator of adipogenesis implicated in the modulation of local and systemic insulin sensitivity', Growth Factors, 34, pp. 210 - 216, http://dx.doi.org/10.1080/08977194.2017.1285764

Lee-Young RS; Hoffman NJ; Murphy KT; Henstridge DC; Samocha-Bonet D; Siebel AL; Iliades P; Zivanovic B; Hong YH; Colgan TD; Kraakman MJ; Bruce CR; Gregorevic P; McConell GK; Lynch GS; Drummond GR; Kingwell BA; Greenfield JR; Febbraio MA; Milliken S; Goodnow C, 2016, 'Glucose-6-phosphate dehydrogenase contributes to the regulation of glucose uptake in skeletal muscle', Molecular Metabolism, 5, pp. 1083 - 1091, http://dx.doi.org/10.1016/j.molmet.2016.09.002

Williams RS; Kozan P; Samocha-Bonet D, 2016, 'The role of dietary acid load and mild metabolic acidosis in insulin resistance in humans', Biochimie, 124, pp. 171 - 177, http://dx.doi.org/10.1016/j.biochi.2015.09.012

Radhakutty A; Mangelsdorf BL; Drake SM; Samocha-Bonet D; Jenkins AB; Heilbronn LK; Smith MD; Thompson CH; Burt MG, 2016, 'Effect of acute and chronic glucocorticoid therapy on insulin sensitivity and postprandial vascular function', Clinical Endocrinology, 84, pp. 501 - 508, http://dx.doi.org/10.1111/cen.12966

Tonks KT; Coster AC; Christopher MJ; Chaudhuri R; Xu A; Gagnon-Bartsch J; Chisholm DJ; James DE; Meikle PJ; Greenfield JR; Samocha-Bonet D; Milliken S; Goodnow C, 2016, 'Skeletal muscle and plasma lipidomic signatures of insulin resistance and overweight/obesity in humans', Obesity, 24, pp. 908 - 916, http://dx.doi.org/10.1002/oby.21448

Chen DL; Liess C; Poljak A; Xu A; Zhang J; Thoma C; Trenell M; Milner B; Jenkins AB; Chisholm DJ; Samocha-Bonet D; Greenfield JR, 2016, 'Erratum: Phenotypic Characterization of Insulin-Resistant and Insulin-Sensitive Obesity (Journal of Clinical Endocrinology and Metabolism 2015 100(11): (4082-4091)); doi: 10.1210/jc.2015-2712', Journal of Clinical Endocrinology and Metabolism, 101, pp. 757, http://dx.doi.org/10.1210/jc.2015-4260

Elshorbagy AK; Jernerén F; Samocha-Bonet D; Refsum H; Heilbronn LK, 2016, 'Serum S-adenosylmethionine, but not methionine, increases in response to overfeeding in humans', Nutrition and Diabetes, 6, http://dx.doi.org/10.1038/nutd.2015.44

Chaudhuri R; Khoo PS; Tonks K; Junutula JR; Kolumam G; Modrusan Z; Samocha-Bonet D; Meoli CC; Hocking S; Fazakerley DJ; Stöckli J; Hoehn KL; Greenfield JR; Yang JYH; James DE; Milliken S; Goodnow C, 2015, 'Cross-species gene expression analysis identifies a novel set of genes implicated in human insulin sensitivity', npj Systems Biology and Applications, 1, pp. 15010, http://dx.doi.org/10.1038/npjsba.2015.10

Chen DL; Liess C; Poljak A; Xu A; Zhang J; Thoma C; Trenell M; Milner B; Jenkins AB; Chisholm DJ; Samocha-Bonet D; Greenfield JR, 2015, 'Phenotypic characterization of insulin-resistant and insulin-sensitive obesity', Journal of Clinical Endocrinology and Metabolism, 100, pp. 4082 - 4091, http://dx.doi.org/10.1210/jc.2015-2712

Williams RS; Heilbronn LK; Chen DL; Coster A; Greenfield JR; Samocha-Bonet D; Milliken S; Goodnow C; Chen D, 2015, 'Dietary acid load, metabolic acidosis and insulin resistance - Lessons from cross-sectional and overfeeding studies in humans', Clinical Nutrition, 35, pp. 1084 - 1090, http://dx.doi.org/10.1016/j.clnu.2015.08.002

Samocha-Bonet D; Chisholm DJ; Holst JJ; Greenfield JR; Milliken S; Goodnow C, 2015, 'L-glutamine and whole protein restore first-phase insulin response and increase glucagon-like peptide-1 in type 2 diabetes patients', Nutrients, 7, pp. 2101 - 2108, http://dx.doi.org/10.3390/nu7042101

Sato K; Samocha-Bonet D; Handelsman DJ; Fujita S; Wittert GA; Heilbronn LK, 2014, 'Serum sex steroids and steroidogenesis-related enzyme expression in skeletal muscle during experimental weight gain in men', Diabetes and Metabolism, 40, pp. 439 - 444, http://dx.doi.org/10.1016/j.diabet.2014.03.006

Samocha-Bonet D; Chisholm DJ; Gribble FM; Coster ACF; Carpenter KH; Jones GRD; Holst JJ; Greenfield JR, 2014, 'Glycemic effects and safety of L-glutamine supplementation with or without sitagliptin in type 2 diabetes patients-a randomized study', PLoS ONE, 9, pp. e113366, http://dx.doi.org/10.1371/journal.pone.0113366

Wu LE; Samocha-Bonet D; Whitworth PT; Fazakerley DJ; Turner N; Biden TJ; James DE; Cantley J, 2014, 'Identification of fatty acid binding protein 4 as an adipokine that regulates insulin secretion during obesity', Molecular Metabolism, 3, pp. 465 - 473, http://dx.doi.org/10.1016/j.molmet.2014.02.005

Milner KL; Jenkins AB; Trenell M; Tid-Ang J; Samocha-Bonet D; Weltman M; Xu A; George J; Chisholm DJ, 2014, 'Eradicating hepatitis C virus ameliorates insulin resistance without change in adipose depots', Journal of Viral Hepatitis, 21, pp. 325 - 332, http://dx.doi.org/10.1111/jvh.12143

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