Select Publications
Journal articles
2014, 'Dominant-activating germline mutations in the gene encoding the PI(3)K catalytic subunit p110δ result in T cell senescence and human immunodeficiency', Nature Immunology, 15, pp. 88 - 97, http://dx.doi.org/10.1038/ni.2771
,2014, 'Human T follicular helper (Tfh) cells and disease', Immunology and Cell Biology, 92, pp. 64 - 71, http://dx.doi.org/10.1038/icb.2013.55
,2013, 'IL-21 signalling via STAT3 primes human näive B cells to respond to IL-2 to enhance their differentiation into plasmablasts', Blood, 122, pp. 3940 - 3950, http://dx.doi.org/10.1182/blood-2013-06-506865
,2013, 'Naive and memory human B cells have distinct requirements for STAT3 activation to differentiate into antibody-secreting plasma cells', Journal of Experimental Medicine, 210, pp. 2739 - 2753, http://dx.doi.org/10.1084/jem.20130323
,2013, 'Signal transducer and activator of transcription 3 (STAT3) mutations underlying autosomal dominant hyper-IgE syndrome impair human CD8+ T-cell memory formation and function', Journal of Allergy and Clinical Immunology, 132, pp. 400 - 411.e9, http://dx.doi.org/10.1016/j.jaci.2013.05.029
,2013, 'The good, the bad and the ugly-T FH cells in human health and disease', Nature Reviews Immunology, 13, pp. 412 - 426, http://dx.doi.org/10.1038/nri3447
,2012, 'Functional STAT3 deficiency compromises the generation of human T follicular helper cells', Blood, 119, pp. 3997 - 4008, http://dx.doi.org/10.1182/blood-2011-11-392985
,2012, 'T cell-B cell interactions in primary immunodeficiencies', Annals of the New York Academy of Sciences, 1250, pp. 1 - 13, http://dx.doi.org/10.1111/j.1749-6632.2011.06361.x
,2011, 'Regulation of T follicular helper cell formation and function by antigen presenting cells', Current Opinion in Immunology, 23, pp. 111 - 118, http://dx.doi.org/10.1016/j.coi.2010.10.007
,2011, 'The regulation and role of T follicular helper cells in immunity', Immunology, 134, pp. 361 - 367, http://dx.doi.org/10.1111/j.1365-2567.2011.03487.x
,2011, 'The role of SAP and SLAM family molecules in the humoral immune response', Annals of the New York Academy of Sciences, 1217, pp. 32 - 44, http://dx.doi.org/10.1111/j.1749-6632.2010.05824.x
,2010, 'Erratum: Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production (Nature Immunology (2009) 10 (1283-1291))', Nature Immunology, 11, pp. 644, http://dx.doi.org/10.1038/ni0710-644a
,2010, 'c-Rel but not NF-κB1 is important for T regulatory cell development', European Journal of Immunology, 40, pp. 677 - 681, http://dx.doi.org/10.1002/eji.201040298
,2010, 'c-Rel phenocopies PKCθ but not Bcl-10 in regulating CD8+ T-cell activation versus tolerance', European Journal of Immunology, 40, pp. 867 - 877, http://dx.doi.org/10.1002/eji.200939445
,2010, 'Sap is necessary for mediating antigen-specific effector functions of CD4+ AND CD8+ T cells', Pathology, 42, pp. S45 - S45, http://dx.doi.org/10.1097/01268031-201042001-00085
,2009, 'Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production', Nature Immunology, 10, pp. 1283 - 1291, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=19898472
,2008, 'Autoimmunity: IL-21: A new player in Th17-cell differentiation (Immunology and Cell Biology (2007) 85, (503-505) DOI: 10.1038/sj.icb.7100114)', Immunology and Cell Biology, 86, pp. 478, http://dx.doi.org/10.1038/sj.icb.7100152
,2007, 'The sound of silence: modulating anergy in T lymphocytes', Current Opinion in Immunology, 19, pp. 658 - 664, http://dx.doi.org/10.1016/j.coi.2007.08.005
,2007, 'CD4+ and CD8+ T cell survival is regulated differentially by protein kinase Cθ c-Rel, and protein kinase B', Journal of Immunology, 178, pp. 2932 - 2939, http://dx.doi.org/10.4049/jimmunol.178.5.2932
,2006, 'Generation and characterization of B7-H4/B7S1/B7x-deficient mice', Molecular and Cellular Biology, 26, pp. 6403 - 6411, http://dx.doi.org/10.1128/MCB.00755-06
,2005, 'Decision criteria for resolving isotype switching conflicts by B cells', European Journal of Immunology, 35, pp. 2949 - 2955, http://dx.doi.org/10.1002/eji.200425719
,2004, 'TCR affinity and negative regulation limit autoimmunity', Nature Medicine, 10, pp. 1234 - 1239, http://dx.doi.org/10.1038/nm1114
,2004, 'PKCθ Signals Activation versus Tolerance In Vivo', Journal of Experimental Medicine, 199, pp. 743 - 752, http://dx.doi.org/10.1084/jem.20031022
,2003, 'Stochastic model of T cell proliferation: A calculus revealing IL-2 regulation of precursor frequencies, cell cycle time, and survival', Journal of Immunology, 170, pp. 4963 - 4972, http://dx.doi.org/10.4049/jimmunol.170.10.4963
,2003, 'Intrinsic differences in the proliferation of naive and memory human B cells as a mechanism for enhanced secondary immune responses', Journal of Immunology, 170, pp. 686 - 694, http://dx.doi.org/10.4049/jimmunol.170.2.686
,1999, 'Quantitative analysis of lymphocyte differentiation and proliferation in vitro using carboxyfluorescein diacetate succinimidyl ester', Immunology and Cell Biology, 77, pp. 516 - 522, http://dx.doi.org/10.1046/j.1440-1711.1999.00874.x
,1999, 'Switching to IgG3, IgG2b, and IgA is division linked and independent, revealing a stochastic framework for describing differentiation', Journal of Immunology, 163, pp. 4707 - 4714
,Conference Papers
2021, 'Dissecting the cellular defects that lead to activated PI3K delta Syndrome (APDS)', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY, pp. 110 - 110, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000753366400330&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2021, 'T cell dysfunction in Activated P13K delta Syndrome explained by cell intrinsic and extrinsic components', in JOURNAL OF IMMUNOLOGY, AMER ASSOC IMMUNOLOGISTS, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000713665800408&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2014, 'Determining the Molecular Requirements for Generating Human T Follicular Helper (Tfh) Cells', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, CZECH REPUBLIC, Prague, pp. S458 - S459, presented at 16th Biennial Meeting of the European-Society-for-Immunodeficiencies, CZECH REPUBLIC, Prague, 29 October 2014 - 01 November 2014, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000347389100688&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2014, 'Dual Impairment of IL-17 and IFN-G Immunity Cause Infections by Candida and Mycobacterium in Humans with RORC Deficiency', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, CZECH REPUBLIC, Prague, pp. S485 - S486, presented at 16th Biennial Meeting of the European-Society-for-Immunodeficiencies (ESID), CZECH REPUBLIC, Prague, 29 October 2014 - 01 November 2014, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000347389100745&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2014, 'Human CTLA4 Haploinsufficiency Causes Severe Immune Dysregulation', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, CZECH REPUBLIC, Prague, pp. S144 - S145, presented at 16th Biennial Meeting of the European-Society-for-Immunodeficiencies, CZECH REPUBLIC, Prague, 29 October 2014 - 01 November 2014, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000347389100011&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2014, 'The Role of STAT3 in the Differentiation and Function of Unconventional T Cells', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, CZECH REPUBLIC, Prague, pp. S441 - S441, presented at 16th Biennial Meeting of the European-Society-for-Immunodeficiencies, CZECH REPUBLIC, Prague, 29 October 2014 - 01 November 2014, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000347389100651&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2012, 'PRIMARY IMMUNE DEFICIENCIES REVEAL THE ROLE OF STAT1 AND STAT3 IN THE ACTIVATION AND DIFFERENTIATION OF HUMAN CD8(+) T CELLS', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, ITALY, Florence, pp. 311 - 312, presented at 15th Biennial Meeting European-Society-for-Immunodeficiency (ESID), ITALY, Florence, 03 October 2012 - 06 October 2012, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000308728900636&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2012, 'SP110 REGULATES NUCLEAR ORPHAN RECEPTOR NUR77-DRIVEN APOPTOSIS IN T CELLS', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, ITALY, Florence, pp. 20 - 21, presented at 15th Biennial Meeting of the European-Society-for-Primary-Immunodeficiency (ESID), ITALY, Florence, 03 October 2012 - 06 October 2012, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000308728900036&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2005, 'Signalling for activation versus anergy: The role of PKCI induced NF-KB activation', in TISSUE ANTIGENS, BLACKWELL PUBLISHING, AUSTRALIA, Melbourne, pp. 396 - 396, presented at 35th Annual SCientific Meeting of the Australasian-Society-for-Immunology/14th International HLA and Immunogenetics Workshops, AUSTRALIA, Melbourne, 29 November 2005 - 02 December 2005, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000233542700151&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2000, 'MSH2-deficiency reduces the rate of switching to all mouse isotypes without altering the regulation of switching by cell division number', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, pp. A1046 - A1046, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000086643100792&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,Conference Abstracts
2022, 'PATIENT PERCEPTIONS OF HEALTH-RELATED QUALITY OF LIFE IN AN AUSTRALIAN ADULT PRIMARY IMMUNODEFICIENCY COHORT', in INTERNAL MEDICINE JOURNAL, WILEY, Vol. 52, pp. 27 - 27, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000862654200072&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2020, 'A divergent transcriptional landscape underpins the development and functional branching of MAIT cells', in JOURNAL OF IMMUNOLOGY, AMER ASSOC IMMUNOLOGISTS, HI, Honolulu, Vol. 204, presented at Annual Meeting of the American-Association-of-Immunologists - Immunology 2020, HI, Honolulu, 08 May 2020 - 12 May 2020, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000589972402321&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2019, 'EVEROLIMUS-INDUCED REMISSION OF KAPOSI'S SARCOMA SECONDARY TO CRYPTIC CTLA4 SPLICING AND HAPLOINSUFFICIENCY', in INTERNAL MEDICINE JOURNAL, WILEY, Vol. 49, pp. 35 - 36, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000488891400106&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2016, 'Mutations underlying autosomal dominant hyper-IgE syndrome impair distinct stages of STAT3 signaling', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 139 - 140, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610400280&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2016, 'Mycobacterial disease and myeloid dendritic cells defects in patients with SPPL2a deficiency', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 777 - 778, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610401757&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2016, 'STAT3 is a critical B-cell intrinsic regulator of functional antibody responses and IgE production', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 849 - 849, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610402097&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2016, 'The role of STAT3 in B cells.', in Pathology, England, Vol. 48 Suppl 1, pp. S45, England, http://dx.doi.org/10.1016/j.pathol.2015.12.111
,2015, 'Impairment of IL-17A/F Immunity to Candida and IFN-g Immunity to Mycobacterium in Patients with RORC Deficiency', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, ARGENTINA, Buenos Aires, Vol. 35, pp. S13 - S14, presented at 4th Meeting of the Latin-American-Society-for-Immunodeficiencies (LASID), ARGENTINA, Buenos Aires, 18 November 2015 - 21 November 2015, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000363977700030&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,Preprints
2024, Both T and B cells contribute to dysregulated activation and differentiation of CD4+T cells in Activated PI3K delta syndrome 1, http://dx.doi.org/10.1101/2024.08.04.606503
,2022, Clonal dynamics of SARS-CoV-2-specific T cells in children and adults with COVID-19, http://dx.doi.org/10.1101/2022.01.30.478400
,2022, Increased core body temperature exacerbates defective protein prenylation in mouse avatars of mevalonate kinase deficiency, http://dx.doi.org/10.1101/2022.02.28.480959
,