By Associate Professor Orazio Vittorio

Preprints

Ehteda A; Simon S; Franshaw L; Giorgi FM; Liu J; Hayden E; Joshi S; Pang CNI; Pandher R; Mayoh C; Tang Y; Rouaen J; Khan A; Ung C; Tolhurst O; Kankean A; Shen S; Gopalakrishnan A; Trebilcock P; Gurova K; Gudkov A; Norris M; Haber M; Vittorio O; Tsoli M; Ziegler DS, 2020, Dual Targeting of the Epigenome Via Facilitates Chromatin Transcription Complex (FACT) and Histone Deacetylase is a Potent Treatment Strategy for DIPG, http://dx.doi.org/10.2139/ssrn.3664176

Zhu J; Graziotto ME; Cottam V; Hawtrey T; Rouaen JRC; Ohno C; Heisler M; Vittorio O; Double KL; New EJ, A Near-Infrared Ratiometric Fluorescent Probe for Detecting Endogenous Cu2+ in the Brain, http://dx.doi.org/10.26434/chemrxiv-2023-mftg1

Mayoh C; Gifford AJ; Terry R; Lau LM; Wong M; Rao P; Shai-Hee T; Saletta F; Khuong-Quang D-A; Qin V; Mateos M; Meyran D; Miller KE; Yuksel A; Mould EV; Bowen-James R; Govender D; Senapati A; Zhukova N; Omer N; Dholaria H; Alvaro F; Tapp H; Diamond Y; Pozza LD; Moore AS; Nicholls W; Gottardo NG; McCowage G; Hansford JR; Khaw S-L; Wood PJ; Catchpoole D; Cottrell CE; Mardis ER; Marshall GM; Tyrrell V; Haber M; Ziegler DS; Vittorio O; Trapani JA; Cowley MJ; Neeson PJ; Ekert PG, A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer, http://dx.doi.org/10.1101/2022.09.16.508179

Raninga P; Zeng B; Moi D; Saletta F; Venkat P; Mayoh C; D'Souza R; Day B; Shai-Hee T; Vittorio O; Mazzieri R; Dolcetti R; Khanna KK, CBL0137 and NKG2A blockade: a novel immuno-oncology combination therapy for Myc-overexpressing triple-negative breast cancers, http://dx.doi.org/10.21203/rs.3.rs-3957241/v1

Poursani EM; Mercatelli D; Raninga P; Bell JL; Saletta F; Kohane FV; Zheng Y; Rouaen J; Jue TR; Michniewicz FT; Kasiou E; Tsoli M; Cirillo G; Waters S; Shai-Hee T; Valli E; Brettle M; Whan R; Vahadat L; Ziegler D; Lock JG; Giorgi FM; Khanna KK; Vittorio O, Copper chelation inhibits TGF-β pathways and suppresses epithelial-mesenchymal transition in cancer, http://dx.doi.org/10.1101/2022.10.03.510707

Stevens KLP; Damstra N; Peh C; Principe N; Phung A-L; Ravensdale J; Wu S; Pham V; Castrogiovanni G; Boon L; Inder-Smith KR; Yeow WS; Howard DL; Ram R; Chopra A; Lesterhuis WJ; Zemek RM; Kong B; Crowe A; Nelson D; Graham RM; Chin WL; Vittorio O; Chee J, Copper chelation reprograms the tumour microenvironment to enhance immune checkpoint blockade therapy in preclinical mesothelioma, http://dx.doi.org/10.64898/2026.07.28.740857

Gargett T; Ebert LM; Truong NTH; Kollis PM; Sedivakova K; Yu W; Yeo ECF; Wittwer NL; Gliddon BL; Tea MN; Ormsby R; Poonnoose S; Nowicki J; Vittorio O; Ziegler DS; Pitson SM; Brown MP, GD2-targeting CAR-T cells enhanced by transgenic IL-15 expression are an effective and clinically feasible therapy for glioblastoma, http://dx.doi.org/10.1101/2022.05.01.490250

Allan KM; Zhang S; Wong SL; Capraro A; McCarron A; Skinner D; Kardia E; Zheng Y; Zhong L; Ng C-A; Bell JL; Farrow N; Umashankar B; Banks C; Herbert C; Kilian KA; Pandzic E; Vittorio O; Vandenberg JI; Lock JG; Jaffe A; Donnelley M; Parsons D; Woodworth BA; Cho D-Y; Waters SA, Gene-Corrected Basal Cells Restore CFTR In Vitro; Transplants Regenerate Epithelium in a Preclinical Sinus Model, http://dx.doi.org/10.1101/2025.07.21.666023

Rennie C; Sives C; Boyton I; Diaz D; Gorrie CA; Vittorio O; Collins-Praino L; Care A, In vivo fate of systemically administered encapsulin protein nanocages and implications for their use in targeted drug delivery, http://dx.doi.org/10.1101/2023.07.16.549228

Poursani EM; Cebon J; Jayachandran A; Rouaen J; Behren A; Vittorio O, Pregnancy-associated plasma protein-A drives melanoma metastasis and immune evasion via IGF signaling, http://dx.doi.org/10.21203/rs.3.rs-7513701/v1

Poursani EM; Pham VV; Ehteda A; Vittorio O, Selective degradation of oncogenic extrachromosomal DNA by type I-E CRISPR, http://dx.doi.org/10.1101/2025.09.21.677573

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