Select Publications
Journal articles
2017, 'Lost in translation: Returning germline genetic results in genome-scale cancer research', Genome Medicine, 9, pp. 41, http://dx.doi.org/10.1186/s13073-017-0430-4
,2017, 'Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis', Science Translational Medicine, 9, http://dx.doi.org/10.1126/scitranslmed.aai8504
,2017, 'Whole-genome landscape of pancreatic neuroendocrine tumours', Nature, 543, pp. 65 - 71, http://dx.doi.org/10.1038/nature21063
,2017, 'Hypermutation In Pancreatic Cancer', Gastroenterology, 152, pp. 68 - 74.e2, http://dx.doi.org/10.1053/j.gastro.2016.09.060
,2016, 'Genomic analyses identify molecular subtypes of pancreatic cancer', Nature, 531, pp. 47 - 52, http://dx.doi.org/10.1038/nature16965
,2016, 'The changing landscape of systemic therapy in advanced pancreatic cancer', Cancer Forum, 40, pp. 53 - 58
,2016, 'Ampullary Cancers Harbor ELF3 Tumor Suppressor Gene Mutations and Exhibit Frequent WNT Dysregulation', Cell Reports, 14, pp. 907 - 919, http://dx.doi.org/10.1016/j.celrep.2015.12.005
,2016, 'Combination of CDK4/6 inhibitor PD-0332991 with standard chemotherapy is synergistic in RB high pancreatic cancer', European Journal of Cancer, 61, pp. S182 - S182, http://dx.doi.org/10.1016/s0959-8049(16)61645-3
,2015, 'Second-line treatment in inoperable pancreatic adenocarcinoma: A systematic review and synthesis of all clinical trials', Critical Reviews in Oncology/Hematology, 96, pp. 483 - 497, http://dx.doi.org/10.1016/j.critrevonc.2015.07.007
,2015, 'Precision medicine for advanced pancreas cancer: The individualized molecular pancreatic cancer therapy (IMPaCT) Trial', Clinical Cancer Research, 21, pp. 2029 - 2037, http://dx.doi.org/10.1158/1078-0432.CCR-15-0426
,2015, 'Whole genomes redefine the mutational landscape of pancreatic cancer', Nature, 518, pp. 495 - 501, http://dx.doi.org/10.1038/nature14169
,2015, 'Rho-associated kinase signalling and the cancer microenvironment: Novel biological implications and therapeutic opportunities', Expert Reviews in Molecular Medicine, 17, http://dx.doi.org/10.1017/erm.2015.17
,2015, 'The dynamics of Rho GTPase signaling and implications for targeting cancer and the tumor microenvironment', Small GTPases, 6, pp. 123 - 133, http://dx.doi.org/10.4161/21541248.2014.973749
,2014, 'Clinical and pathologic features of familial pancreatic cancer', Cancer, 120, pp. 3669 - 3675, http://dx.doi.org/10.1002/cncr.28863
,2014, 'Adjuvant chemotherapy in elderly patients with pancreatic cancer', British Journal of Cancer, 110, pp. 313 - 319, http://dx.doi.org/10.1038/bjc.2013.722
,2014, 'Personalising pancreas cancer treatment: When tissue is the issue', World Journal of Gastroenterology, 20, pp. 7849 - 7863, http://dx.doi.org/10.3748/wjg.v20.i24.7849
,2013, 'The IMPaCT trial: Individualised Molecular Pancreatic Cancer Therapy. A pilot, randomized, open label Phase II trial assessing first line treatment with gemcitabine or personalized treatment based on tumour molecular signature in patients with metastatic pancreatic cancer.', MOLECULAR CANCER THERAPEUTICS, 12, http://dx.doi.org/10.1158/1535-7163.TARG-13-A75
,2013, 'Clinical and molecular characterization of HER2 amplified-pancreatic cancer', Genome Medicine, 5, pp. 78, http://dx.doi.org/10.1186/gm482
,2013, 'Pharmacologic and radiotherapeutic interventions for advanced pancreatic cancer', Cochrane Database of Systematic Reviews, 2013, http://dx.doi.org/10.1002/14651858.CD010584
,2013, 'From functional genomics to precision medicine: The therapeutic potential of targeting ROCK signaling in pancreatic cancer.', Journal of Clinical Oncology, 31, pp. e15029 - e15029, http://dx.doi.org/10.1200/jco.2013.31.15_suppl.e15029
,2013, 'Histomolecular phenotypes and outcome in adenocarcinoma of the ampulla of vater', Journal of Clinical Oncology, 31, pp. 1348 - 1356, http://dx.doi.org/10.1200/JCO.2012.46.8868
,2012, 'INDIVIDUALISED MEASUREMENT OF TUMOUR-DERIVED CIRCULATING DNA IN PATIENTS WITH PANCREATIC CANCER: A MARKER OF PROGNOSIS AND THERAPEUTIC RESPONSE', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, 8, pp. 36 - 36, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000306960100002&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2012, 'Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes', Nature, 491, pp. 399 - 405, http://dx.doi.org/10.1038/nature11547
,2012, 'The prognostic and predictive value of serum CA19.9 in pancreatic cancer', Annals of Oncology, 23, pp. 1713 - 1722, http://dx.doi.org/10.1093/annonc/mdr561
,2006, 'Chemotherapy and radiotherapy for pancreatic cancer', Cochrane Database of Systematic Reviews, 4
,2004, 'Role of FDG-PET in surgical management of patients with colorectal liver metastases', ANZ Journal of Surgery, 74, pp. 646 - 652, http://dx.doi.org/10.1111/j.1445-1433.2004.02948.x
,Conference Papers
2023, '675 Safety and tolerability of magrolimab combination therapy in patients with recurrent or metastatic head and neck squamous cell carcinoma (RM-HNSCC)', in Regular and Young Investigator Award Abstracts, BMJ Publishing Group Ltd, pp. A765 - A766, presented at SITC 38th Annual Meeting (SITC 2023) Abstracts, http://dx.doi.org/10.1136/jitc-2023-sitc2023.0675
,2021, 'Immunotherapy improves survival in first-line treatment of extensive-stage small-cell lung cancer: A systematic review and meta-analysis', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY, pp. 164 - 164, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000717281500260&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2021, 'Investigating and addressing clinical variation in lung cancer - Analysis from the EnRICH Program', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY, pp. 31 - 31, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000693805000052&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2021, 'Activin-A and GDF-11 as Predictive Biomarkers for Platinum Response in Non-Small Cell Lung Cancer', in JOURNAL OF THORACIC ONCOLOGY, ELSEVIER SCIENCE INC, pp. S450 - S450, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000631349601199&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2020, 'Psychosocial experiences of lung cancer survivors: A qualitative study', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY, pp. 194 - 194, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000790145400302&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2018, 'Development of overall survival (OS) and progression free survival (PFS) nomograms for Australian patients with locoregionally advanced oropharyngeal squamous cell carcinoma (LA OPSCC)', in Annals of oncology : official journal of the European Society for Medical Oncology, pp. viii389, http://dx.doi.org/10.1093/annonc/mdy287.049
,2017, 'Clinical utilization of targetable molecular results in pancreatic cancer: Longer-term outcomes from the Individualized Molecular Pancreatic Cancer Therapy (IMPACT) trial', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, IL, Chicago, presented at 53rd Annual Clinical Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 02 June 2017 - 07 June 2017, http://dx.doi.org/10.1200/JCO.2017.35.4_suppl.314
,2016, 'Combination of CDK4/6 inhibitor PD-0332991 with standard chemotherapy is synergistic in RB high pancreatic cancer', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, pp. S182 - S182, http://dx.doi.org/10.1016/S0959-8049(16)61645-3
,2015, 'Precision medicine for advanced pancreas cancer: the individualized molecular pancreatic cancer therapy (IMPaCT) trial', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, PA, Philadelphia, presented at 106th Annual Meeting of the American-Association-for-Cancer-Research (AACR), PA, Philadelphia, 18 April 2015 - 22 April 2015, http://dx.doi.org/10.1158/1538-7445.AM2015-CT210
,2014, 'PRECISION MEDICINE FOR ADVANCED PANCREAS CANCER: EARLY LESSONS LEARNED FROM NEGOTIATING THE PITFALLS OF A MOLECULAR THERAPEUTICS TRIAL IN A POOR PROGNOSIS CANCER', in ANNALS OF ONCOLOGY, OXFORD UNIV PRESS, SPAIN, Madrid, presented at 39th ESMO Congress (ESMO), SPAIN, Madrid, 26 September 2014 - 30 September 2014, http://dx.doi.org/10.1093/annonc/mdu358.59
,2014, 'Duration of systemic therapy for ovarian cancer: A systematic review and meta-analysis.', in JOURNAL OF CLINICAL ONCOLOGY, LIPPINCOTT WILLIAMS & WILKINS, IL, Chicago, presented at 50th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 30 May 2014 - 03 June 2014, http://dx.doi.org/10.1200/jco.2014.32.15_suppl.5549
,2014, 'Targeted therapies in the treatment of advanced pancreatic adenocarcinoma (PC): A systematic review and meta-analysis of randomized trials', in JOURNAL OF CLINICAL ONCOLOGY, LIPPINCOTT WILLIAMS & WILKINS, IL, Chicago, presented at 50th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), IL, Chicago, 30 May 2014 - 03 June 2014, http://dx.doi.org/10.1200/jco.2014.32.15_suppl.e15209
,2014, 'Survival benefit of second-line chemotherapy in advanced pancreatic adenocarcinoma: A systematic review of the literature', in JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, CA, San Francisco, presented at Gastrointestinal Cancers Symposium, CA, San Francisco, 16 January 2014 - 18 January 2014, http://dx.doi.org/10.1200/jco.2014.32.3_suppl.296
,2014, 'GENOMIC CLASSIFIER FOR PANCREATIC DUCTAL ADENOCARCINOMA THERAPEUTIC RESPONSE', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY-BLACKWELL, pp. 44 - 44, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000339716500009&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2014, 'PHARMACOLOGIC INTERVENTIONS FOR ADVANCED PANCREATIC CANCER (PC) - A META-ANALYSIS COMPARING GEMCITABINE ALONE (G) VERSUS GEMCITABINE COMBINATIONS (GCs)', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY-BLACKWELL, pp. 48 - 48, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000339716500014&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2013, 'A molecular pre-operative prognostic nomogram for resectable pancreatic cancer', in Cancer Research, American Association for Cancer Research, Washington, DC, presented at 104th Annual Meeting of the American-Association-for-Cancer-Research (AACR), Washington, DC, 06 April 2013 - 10 April 2013, http://dx.doi.org/10.1158/1538-7445.AM2013-1156
,2012, 'Abstract B64: A molecular preoperative prognostic nomogram for resectable pancreatic cancer.', in Tumor Biology, American Association for Cancer Research, pp. B64 - B64, presented at Abstracts: AACR Special Conference on Pancreatic Cancer: Progress and Challenges; June 18-21, 2012; Lake Tahoe, NV, http://dx.doi.org/10.1158/1538-7445.panca2012-b64
,2012, 'Adjuvant chemotherapy is effective in elderly patients with resected pancreatic cancer', in Asia-Pacific Journal of Clinical Oncology, Blackwell Publishing Asia, Australia, pp. 30 - 34, presented at ANZUP Annual Scientific Meeting, -
,Conference Posters
2013, 'From function genomics to precision medicine: the therapeutic potential of targeting rock signalling in pancreatic cancer', Chicago, IL, Vol. 9, pp. 53 - 53, presented at ASCO Annual Meeting, Chicago, IL, 31 May 2013 - 04 June 2013, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=000329462300024&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,Conference Presentations
2014, 'From functional genomics to precision medicine: Using well annotated models to define personalised treatment strategies for pancreatic cancer', https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000341276000017&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,Conference Abstracts
2023, 'Activin-A, GDF-11 and TGF-beta as predictive biomarkers for platinum chemotherapy in advanced non-small cell lung cancer', in RESPIROLOGY, WILEY, Vol. 28, pp. 39 - 39, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:001002468800070&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2023, 'Single cell RNA sequencing reveals phenotypic predispositions to developing lung cancer in neversmokers', in RESPIROLOGY, WILEY, Vol. 28, pp. 13 - 13, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:001002468800021&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2023, 'The incidence of rare and compound mutations of EGFR in non-small cell lung cancer and their potential clinical significance', in Respirology, Wiley, Vol. 28, pp. 28 - 29, presented at Australian Lung Cancer Conference 2023
,2022, 'Chemotherapy response following immunotherapy in metastatic head and neck cancer; a single-centre experience', in Asia Pacific Journal of Clinical Oncology, Wiley, Brisbane, Queensland, Vol. 18, pp. 139 - 140, presented at COSA’s 49th Annual Scientific Meeting, Brisbane, Queensland, 02 November 2022 - 04 November 2022, http://dx.doi.org/10.1111/ajco.13869
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