By Conjoint Professor Maria Kavallaris

Journal articles

Tait AS; Kavallaris M; etievant C; Unkown A; Barret J; Hill B, 2001, 'Markedly diminished drug-resistance including properties of vinflunine (20`, 20`- difluro- 3`, 4` - dihydrovinorelbine) relative tovinorelbine, identified in murine and human tumour cells in vivo and in vitro, with clinical implications', Cancer Chemotherapy and Pharmacology, pp. 62 - 70

Kavallaris M; Tait AS; Norris MD; Haber M; Walsh B; He L; Horwitz SB, 2001, 'Multiple microtubule alterations are associated with vinca alkaloid resistance in human leukemia cells', Cancer research, pp. 5803 - 5809

Kavallaris M; Burkhart CA; Horwitz SB, 2001, 'The role of beta-tubulin isotypes in resistance to antimitotic drugs', Biochimica et Biophysica ACTA, 1471, pp. 1 - 9

Murphy KD; Ranganathan V; Farnsworth ML; Kavallaris M; Lock RB, 2000, 'Bcl-2 inhibits Bax translocation from cytosol to mitochondria during drug-induced apoptosis of human tumour cells', Cell death and differentiation, pp. 102 - 111

Haber M; Bordow SB; Gilbert J; Madafiglio J; Kavallaris M; Marshall GM; Mechetner EB; Fruehauf JP; Tee L; Cohn S; Salwen H; Schmidt ML; Norris MD; Gilbert J, 1999, 'Altered expression of the MYCN Oncogene modulates MRP gene expression and response to cytotoxic drugs in neuroblastoma cells', Oncogene, 18, pp. 2777 - 2782

Kavallaris M; Burkhart CA; Horwitz SB, 1999, 'Antisense oligonucleotides to class III B-tubulin sensitise drug-resistant cells to Taxol.', British Journal of Cancer, pp. 1020 - 1025

Kavallaris M; Gardaneh M; Cheung BB; Camacho M; Hocker JE; Norris MD; Haber M; Marshall GM, 1998, 'In Vitro effects of MYCN sense and antisense expression in MYCN-amplified human neuroblastoma cells', Anticancer Research, pp. 1793 - 1798

Gifford AJ; Kavallaris M; Madafiglio J; Matherly LH; Stewart BW; Haber M; Norris MD, 1998, 'P-glycoprotein-mediated methotrexate resistance in CCRF-CEM sublines deficient in Methotrexate accumulation due to a point mutation in the reduced folate carrier gene', International Journal of Cancer, pp. 176 - 181

Kavallaris M, 1997, 'The role of multidrug resistance-associated protein (MRP) expression in multidrug resistance', Anti Cancer Drugs, 8, pp. 17 - 25, http://dx.doi.org/10.1097/00001813-199701000-00002

Norris MD; Bordow SB; Haber PS; Marshall GM; Kavallaris M; Madafiglio J; Cohn S; Schmidt ML; Hipfner DR; Deeley RG; Cole SP; Haber M; Salwen H, 1997, 'EVIDENCE THAT THE N-MYC ONCOGENE REGULATES MRP GENE EXPRESSION IN NEUROBLASTOMA', European Journal of Cancer, pp. 1911 - 1916

Kavallaris M; Kuo DY; Burkhart CA; Regl DL; Norris MD; Haber M; Horwitz SB, 1997, 'TAXOL-RESISTANT EPITHELIAL OVARIAN TUMORS ARE ASSOCIATED WITH ALTERED EXPRESSION OF SPECIFIC {BETA}-TUBLIN ISOTYPES', Journal of Clinical Investigation, 100, pp. 1282 - 1293

Kavallaris M; Leary JA; Barrett JA; Friedlander ML, 1996, 'MDR1 and multidrug resistance-associated protein (MRP) gene expression in epithelial ovarian tumors', Cancer Letters, 102, pp. 7 - 16, http://dx.doi.org/10.1016/0304-3835(96)04143-2

Norris MD; De Graaf D; Haber M; Kavallaris M; Madafiglio J; Gilbert J; Kwan E; Stewart BW; Mechetner EB; Gudkov AV; Roninson IB, 1996, 'Involvement of MDR1 P-Glycoprotein in multifactorial resistance to methotrexate', International Journal of Cancer, pp. 613 - 619

Haber M; Norris MD; Kavallaris M; Camacho M; Madafiglio J; Baker C; White L; Stewart BW, 1995, 'An assay for the determination of reduced methotrexate accumulation in cells displaying limited viability in vitro', Cancer Letters, pp. 49 - 55

Norris MD; Haber M; Gilbert J; Kavallaris M; Marshall GM; Stewart BW, 1994, 'N-myc gene amplification in neuroblastoma determined by the polymerase chain reaction.', Progress in Clinical and Biological Research, 385, pp. 27 - 33

Gilbert J; Norris MD; Haber M; Kavallaris M; Marshall GM; Stewart BW, 1993, 'Determination of n-myc gene amplification in neuroblastoma by differential polymerase chain reaction', Molecular and Cellular Probes, 7, pp. 227 - 234, http://dx.doi.org/10.1006/mcpr.1993.1033

Pittman SM; Kavallaris M; Stewart BW, 1993, 'Karyotypic analysis of CCRF-CEM and drug-resistant cell lines with stable and unstable ploidy', Cancer Genetics and Cytogenetics, 66, pp. 54 - 62, http://dx.doi.org/10.1016/0165-4608(93)90149-G

Kavallaris M; Madafiglio J; Norris MD; Haber M, 1993, 'Resistance to Tetracycline, a Hydrophilic Antibiotic, Is Mediated by P-Glycoprotein in Human Multidrug-Resistant Cells', Biochemical and Biophysical Research Communications, 190, pp. 79 - 85, http://dx.doi.org/10.1006/bbrc.1993.1013

TELFORD DJ; KAVALLARIS M; WHITE L; NORRIS MD; BRIAN MJ; STEWART BW, 1992, 'Association of N‐myc amplification with neuroblastoma: The Australian and New Zealand experience', Journal of Paediatrics and Child Health, 28, pp. 58 - 63, http://dx.doi.org/10.1111/j.1440-1754.1992.tb02619.x

Kavallaris M; Haber M; Norris MD; Matherly LH; Stewart BW, 1991, 'Characterization of Mechanisms Mediating Drug Resistance in Human Leukemic Cells Selected with High Concentration Methotrexate', Pteridines, 3, pp. 119 - 121, http://dx.doi.org/10.1515/pteridines.1991.3.12.119

Norris MD; Haber M; Kavallaris M; Brian MJ; Lutze LH; White L; Stewart BW, 1991, 'Reduced drug accumulation as the mechanism of extreme clinical resistance to methotrexate in the human T‐cell leukemia xenograft, LALW‐2', Cancer, 68, pp. 981 - 987, http://dx.doi.org/10.1002/1097-0142(19910901)68:5<981::AID-CNCR2820680512>3.0.CO;2-W

Stewart BW; Kavallaris M; Catchpoole D; Norris MD, 1991, 'Two classes of single-stranded regions evident in deproteinized preparations of replicating DNA isolated from mammalian cells', Experimental Cell Research, 192, pp. 639 - 642, http://dx.doi.org/10.1016/0014-4827(91)90087-B

Kavallaris M; Haber M; Norris MD; Pittman SM; Reed C; Stewart BW, 1990, 'Phenotypic and cytogenetic analysis of atypical multidrug resistance in human leukaemic cells selected with methotrexate at high concentration', Cancer Letters, 51, pp. 193 - 201, http://dx.doi.org/10.1016/0304-3835(90)90102-4

Haber M; Norris MD; Kavallaris M; White L; Stewart BW; Bell DR; Davey RA, 1989, 'Atypical Multidrug Resistance in a Therapy-induced Drug-resistant Human Leukemia Cell Line (LALW-2): Resistance to Vinca Alkaloids Independent of P-Glycoprotein', Cancer Research, 49, pp. 5281 - 5287

Haber M; Reed C; Kavallaris M; Norris MD; Stewart BW, 1989, 'Resistance to drugs associated with the multidrug resistance phenotype following selection with high-concentration methotrexate', Journal of the National Cancer Institute, 81, pp. 1250 - 1254, http://dx.doi.org/10.1093/jnci/81.16.1250

HABER M; KAVALLARIS M; STEWART BW, 1986, '2-STAGE INCORPORATION OF THYMIDINE TRIPHOSPHATE INTO MAMMALIAN DNA AS INDICATED BY CHROMATOGRAPHY ON BENZOYLATED DEAE-CELLULOSE', JOURNAL OF CHROMATOGRAPHY, 382, pp. 127 - 134, http://dx.doi.org/10.1016/S0378-4347(00)83511-2

Haber M; Kavallaris M; Stewart BW, 1986, 'Two-stage incorporation of thymidine triphosphate into mammalian DNA as indicated by chromatography on benzoylated DEAE-cellulose', Journal of Chromatography B Biomedical Sciences and Applications, 382, pp. 135 - 145, http://dx.doi.org/10.1016/S0378-4347(00)83512-4

Haber M; Kavallaris M; Stewart BW, 1986, 'Two-stage incorporation of thymidine triphosphate into mammalian DNA as indicated by chromatography on benzoylated DEAE-cellulose', Journal of Chromatography Biomedical Applications, Vol. 382, pp. 127 - 134

Conference Papers

Connerty P; Moles E; deBock C; Jayatilleke N; Smith JL; Meshinchi S; Mayoh C; Kavallaris M; Lock RB, 2021, 'Abstract P143: Development of siRNA-loaded lipid nanoparticles targeting long non-coding RNA LINC01257 as a novel and safe therapeutic approach for paediatric acute myeloid leukaemia', in Molecular Cancer Therapeutics, American Association for Cancer Research (AACR), pp. p143 - p143, http://dx.doi.org/10.1158/1535-7163.targ-21-p143

Ung C; Tsoli M; Liu J; Cassano D; Upton D; Ehteda A; Mansfield F; Failes T; Kavallaris M; Arndt G; Vittorio O; Voliani V; Cirilo G; Ziegler DS, 2020, 'NANOPARTICLE DELIVERY OF DOXORUBICIN FOR THE TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, pp. 286 - 286, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000606080100048&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Brayford S; Teo WS; Parker A; McVeigh L; McCarroll JA; Kavallaris M, 2020, 'Abstract 1442: Identifying the molecular basis by which βIII-tubulin promotes tumor cell survival and drug resistance in non-small cell lung cancer', in Cancer Research, American Association for Cancer Research (AACR), pp. 1442 - 1442, http://dx.doi.org/10.1158/1538-7445.am2020-1442

Ma Z; Esser L; Lai M; Leiske MN; Forgham H; Wong SW; Mansfeld FM; Lewis CR; Davis TP; Quinn J; Phillips P; Kavallaris M; McCarroll JA, 2020, 'Development and Biological Optimization of Star-Shaped Polymeric Nanoparticles for the Delivery of Therapeutic siRNA to Lung Cancer Cells In Vitro and In Vivo', in MOLECULAR THERAPY, CELL PRESS, ELECTR NETWORK, pp. 347 - 348, presented at 23rd Annual Meeting of the American-Society-for-Gene-and-Cell-Therapy, ELECTR NETWORK, 12 May 2020 - 15 May 2020, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000530089301322&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Bailey BJ; Lilja A; Strong C; Moline K; Kavallaris M; Hughes RT; McGhee J, 2019, 'Multi-user immersive virtual reality prototype for collaborative visualization of microscopy image data', in Proceedings Vrcai 2019 17th ACM SIGGRAPH International Conference on Virtual Reality Continuum and Its Applications in Industry, http://dx.doi.org/10.1145/3359997.3365730

Voli F; Lerra L; Kimpton K; Saletta F; Shen S; Cirillo G; Kavallaris M; Vittorio O, 2019, 'Abstract 3224: Copper homeostasis: A new player in anti-tumor immune response', in Cancer Research, American Association for Cancer Research (AACR), pp. 3224 - 3224, http://dx.doi.org/10.1158/1538-7445.am2019-3224

Grand ML; Kimpton K; Gana C; Valli E; Mayoh C; Kavallaris M, 2019, 'Abstract 3435: Targeting AKT activity inhibits MYCN and sensitizes neuroblastoma to chemotherapeutic agents', in Molecular and Cellular Biology / Genetics, American Association for Cancer Research, pp. 3435 - 3435, presented at Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA, http://dx.doi.org/10.1158/1538-7445.sabcs18-3435

Atapattu L; Utama R; O'Mahony A; Fife C; Baek J; Allard T; O'Mahony K; Ribeiro J; Gaus K; Gooding J; Kavallaris M, 2018, 'Abstract 5022: Precision medicine: High-throughput 3D bioprinting of embedded multicellular cancer spheroids', in Cancer Research, American Association for Cancer Research (AACR), pp. 5022 - 5022, http://dx.doi.org/10.1158/1538-7445.am2018-5022

Ercole F; Mansfeld F; Kavallaris M; Whittaker M; Halls M; Davis T; Quinn J, 2017, 'Triggering cellular signalling processes with novel macromolecular hydrogen sulfide donors', in ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, AMER CHEMICAL SOC, CA, San Francisco, presented at 253rd National Meeting of the American-Chemical-Society (ACS) on Advanced Materials, Technologies, Systems, and Processes, CA, San Francisco, 02 April 2017 - 06 April 2017, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000430569107588&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Teo WS; Dwarte T; Failes TW; Arndt GM; McCarroll JA; Kavallaris M, 2017, 'High throughput kinase inhibitor screen reveals novel inhibitor combinations acting in synergy with TUBB3/beta III-tubulin suppression in non-small cell lung cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, DC, Washington, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), DC, Washington, 01 April 2017 - 05 April 2017, http://dx.doi.org/10.1158/1538-7445.AM2017-4037

Parker AL; Teo WS; McCarroll JA; Kavallaris M, 2017, 'Structural domains of ss III-Tubulin regulate multiple stress responses and influence cell growth and survival in glucose-deprived non-small cell lung cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, DC, Washington, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), DC, Washington, 01 April 2017 - 05 April 2017, http://dx.doi.org/10.1158/1538-7445.AM2017-5484

Vittorio O; Brandl M; Cirillo G; Kimpton K; Hinde E; Duong HTT; Boyer C; Flemming C; Yee EMH; Kumar N; Parmar A; Pascali G; Charil A; Haber M; Norris M; Kavallaris M, 2016, 'Abstract 1340: Dextran-Catechin conjugate: An anticancer nano-modified natural compound targeting copper metabolism in neuroblastoma', in Cancer Research, American Association for Cancer Research (AACR), pp. 1340 - 1340, http://dx.doi.org/10.1158/1538-7445.am2016-1340

Kao FCL; Failes T; Arndt GM; Norris M; Kavallaris M, 2015, 'Abstract 3660: Discovery of a small molecule TUBB3/βIII-tubulin modulator in lung cancer', in Cancer Research, American Association for Cancer Research (AACR), pp. 3660 - 3660, http://dx.doi.org/10.1158/1538-7445.am2015-3660

Nakano M; Shirai R; Ito J; Kavallaris M; Packer N, 2014, 'Acquired drug resistance by decrease of sialylated glycans on acute lymphoblastic leukemia cell-membrane glycoproteins', in GLYCOBIOLOGY, OXFORD UNIV PRESS INC, HI, Honolulu, pp. 1217 - 1217, presented at Joint Meeting of the Society-for-Glycobiology (SFG) and the Japanese-Society-of-Carbohydrate-Research (JSCR), HI, Honolulu, 16 November 2014 - 19 November 2014, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000344670300365&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Teo J; Boyer C; Sharbeen G; Sagnella S; Liu J; Youkhana J; Duong HT; Goldstein D; Davis TP; Kavallaris M; McCarroll J; Phillips PA, 2014, 'Design and Synthesis of Novel PEGylated Star Nanoparticles as Delivery Agents for Short-Interfering RNA (siRNA) to Pancreatic Cancer Cells', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, pp. 1416 - 1416, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000344362600356&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Parker A; McCarroll JA; Kavallaris M, 2014, 'Abstract 326: βIII-Tubulin and cell survival: Novel role in endoplasmic reticulum stress and autophagy in non-small cell lung cancer', in Cancer Research, American Association for Cancer Research (AACR), pp. 326 - 326, http://dx.doi.org/10.1158/1538-7445.am2014-326

McCarroll JA; Gan PP; Erlich RB; Liu M; Dwarte T; Akerfeldt MC; Chang M; Shum MS; Byrne F; Kavallaris M, 2014, 'beta III-tubulin is required for the tumorigenic phenotype and resistance to anoikis via the PTEN/AKT signaling axis in non-small cell lung cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CA, San Diego, presented at 105th Annual Meeting of the American-Association-for-Cancer-Research (AACR), CA, San Diego, 05 April 2014 - 09 April 2014, http://dx.doi.org/10.1158/1538-7445.AM2014-2076

Fife CM; Byrne FL; Sagnella SM; Davis TP; McCarroll JA; Kavallaris M, 2014, 'Stathmin regulates cell migration, invasion and transendothelial migration via RhoA activation in neuroblastoma', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CA, San Diego, presented at 105th Annual Meeting of the American-Association-for-Cancer-Research (AACR), CA, San Diego, 05 April 2014 - 09 April 2014, http://dx.doi.org/10.1158/1538-7445.AM2014-4987

Yi H; Wang J; Kavallaris M; Wang JY, 2013, 'Lgr4-Mediated Potentiation Of Wnt/beta-Catenin Signaling Promotes MLL Leukemogenesis Via An Rspo3/Wnt3a-Gnaq Pathway In Leukemic Stem Cells', in BLOOD, AMER SOC HEMATOLOGY, LA, New Orleans, presented at 55th Annual Meeting of the American-Society-of-Hematology, LA, New Orleans, 07 December 2013 - 10 December 2013, http://dx.doi.org/10.1182/blood.V122.21.887.887

Sharbeen G; Liu J; McCarroll J; Youkhana J; Teo J; McCarthy N; Goldstein D; Kavallaris M; Phillips PA, 2013, 'beta III-Tubulin is a Novel Therapeutic Target for the Treatment of Pancreatic Cancer', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, pp. 1381 - 1381, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000330468400204&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Teo J; Boyer C; Liu J; Sharbeen G; Erlich R; Youkhana J; Duong HT; Goldstein D; Davis TP; Kavallaris M; McCarroll J; Phillips PA, 2013, 'Inhibition of beta III-Tubulin Using a Novel Nanoparticle-siRNA Approach Sensitizes Pancreatic Cancer Cells to Chemotherapy', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, pp. 1385 - 1385, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000330468400222&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Sharbeen G; Liu J; Mccarroll J; Youkhana J; Teo J; Mccarthy N; Goldstein D; Kavallaris M; Phillips PA, 2013, 'beta III-tubulin is a novel therapeutic target for the treatment of pancreatic cancer', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY-BLACKWELL, pp. 12 - 12, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000324106900022&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Back to profile page