By Conjoint Professor Paul Ekert

Conference Abstracts

Sadras T; Brown LM; Salib A; Liu PY; Mayoh C; Tyrrell V; Cowley MJ; Ekert PG, 2024, 'Putting function back into paediatric cancer genomics - modelling the therapeutic implications of novel genomic features', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CANADA, Toronto, Vol. 84, presented at AACR Special Conference in Cancer Research: Advances in Pediatric Cancer Research, CANADA, Toronto, 05 September 2024 - 08 September 2024, http://dx.doi.org/10.1158/1538-7445.PEDIATRIC24-B004

Liu PY; He S; Mayoh C; Salib A; De Weck A; Ekert PG, 2024, 'Unravelling the role of METTL1 in Myc driven pediatric cancers using CRISPR Cas13d', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CANADA, Toronto, Vol. 84, presented at AACR Special Conference in Cancer Research: Advances in Pediatric Cancer Research, CANADA, Toronto, 05 September 2024 - 08 September 2024, http://dx.doi.org/10.1158/1538-7445.PEDIATRIC24-A012

McKay C; Power P; Staunton J; Sriharan S; Jessop S; Zhukova N; Trinder S; Govender D; Barahona P; Gifford AJ; Mignone C; Xie A; Tax G; Tsoli M; Dolman E; Mayoh C; Wong M; Cowley M; Marshall G; Trahair T; Lock RB; Ekert P; Haber M; Tyrell V; Lau L; Manoharan* N; Ziegler* DS; Khuong-Quang* D-A, 2024, 'DIPG-48. PRECISION GUIDED THERAPY PROVIDES CLINICAL BENEFIT IN H3K27-ALTERED DIFFUSE MIDLINE GLIOMA', in Neuro-Oncology, Oxford University Press (OUP), Vol. 26, http://dx.doi.org/10.1093/neuonc/noae064.101

Brown LM; Mayoh C; Mateos PA; De Weck A; Salomon R; Sadras T; Manoharan N; Wong M; Cowley MJ; Ekert PG, 2024, 'Right oncogene, wrong tumor - CBL mutations in pediatric CNS and solid tumors', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CA, San Diego, Vol. 84, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), CA, San Diego, 05 April 2024 - 10 April 2024, http://dx.doi.org/10.1158/1538-7445.AM2024-1770

Zhao A; Brown LM; Fareh M; Ekert PG, 2024, 'Abstract 1094: Utilizing CRISPR-Cas13 as a novel functional genomics tool to characterize PAX3-FOXO1 in alveolar rhabdomyosarcoma', in Cancer Research, American Association for Cancer Research (AACR), Vol. 84, pp. 1094 - 1094, http://dx.doi.org/10.1158/1538-7445.am2024-1094

Lau L; Khoung-Quang DA; Chelsea M; Wong M; Barahona P; Ajuyah P; Senapati A; Nagabushan S; Sherstyuk A; Altekoester AK; Fuentes-Bolanos N; Sullivan A; Mateos M; Tyrrell N; Haber M; Trahair T; Cowley M; Marshall G; Ekert P; Ziegler D, 2024, '438 (PB426): Precision-guided treatment improves outcomes for children with highrisk cancers', in European Journal of Cancer, Elsevier, Vol. 211, pp. 114946, http://dx.doi.org/10.1016/j.ejca.2024.114946

Mayoh C; Meyran D; Nguyen T; Darcy C; Ziegler D; Haber M; Trapani J; Ekert P; Neeson P, 2022, 'PRECISION MEDICINE REVEALS A HETEROGENOUS TUMOUR IMMUNE MICROENVIRONMENT IN PAEDIATRIC GLIOMAS', in PEDIATRIC BLOOD & CANCER, WILEY, Vol. 69, pp. S327 - S328, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000859203901292&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Daniel P; Sun C; Koptyra M; Drinkwater C; Chew N; Bradshaw G; Loi M; Shi C; Tourchi M; Parackal S; Chong WC; Fernando D; Adjumain S; Hoang N; Habarakada D; Sooraj D; Crombie D; Zhukova N; Jones C; Rubens J; Raabe E; Vinci M; Dun M; Ludlow L; Nazarian J; Fletcher J; Ekert P; Ziegler D; Loh AHP; Low SYY; Monje M; Neeman N; Williams B; Resnick A; Gough D; Cain J; Firestein R, 2022, 'THE CHILDHOOD BRAIN CANCER CELL LINE ATLAS: A RESOURCE FOR BIOMARKER IDENTIFICATION AND THERAPEUTIC DEVELOPMENT', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, GERMANY, Hamburg, Vol. 24, pp. 172 - 172, presented at 20th International Symposium on Pediatric Neuro-Oncology (ISPNO) / Annual Meeting of the Brain-Tumor-Group-of-SIOP-Europe (SIOPE-BTG), GERMANY, Hamburg, 11 June 2022 - 15 June 2022

Hu W; Zhao W; Kumar A; Singh GJ; Qi S; Casan J; Shembery C; Fong D; Zerbato JM; Symons J; Rudraraju R; Purcell D; Haber M; Voskoboinik I; Ekert PG; Lewin S; Trapani J; Fareh M, 2022, 'De novo design of CRISPR-Cas13b enables efficient silencing of SARS-CoV-2 variants and tumour pathogenic RNAs with near single-base precision', in Pathology, Elsevier, Vol. 54, pp. s15 - s16, http://dx.doi.org/10.1016/j.pathol.2021.12.057

Mayoh C; Terry RL; Wong M; Lau LM; Khuong-Quang DA; Mateos MK; Tyrrell V; Haber M; Ziegler DS; Cowley MJ; Trapani JA; Neeson PJ; Ekert PG, 2021, 'Abstract 3044: The unexplored immune landscape of high-risk pediatric cancers', in Cancer Research, American Association for Cancer Research (AACR), Vol. 81, pp. 3044 - 3044, http://dx.doi.org/10.1158/1538-7445.am2021-3044

Mayoh C; Terry RL; Wong M; Lau LM; Khuong-Quang DA; Mateos MK; Tyrrell V; Haber M; Ziegler DS; Cowley MJ; Trapani JA; Neeson PJ; Ekert PG, 2021, 'The unexplored immune landscape of high-risk pediatric cancers.', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, PA, Philadelphia, Vol. 81, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), PA, Philadelphia, 10 April 2021 - 21 May 2021

Khuong-Quang D-A; Nagabushan S; Manoharan N; Arndt G; Barahona P; Cowley MJ; Ekert PG; Failes T; Bolanos NF; Gauthier M; Gifford AJ; Haber M; Kumar A; Lock RB; Marshall GM; Mayoh C; Mould E; Norris MD; Gopalakrishnan A; Omer N; Trebilcock P; Trahair TN; Tsoli M; Tucker K; Wong M; Tyrrell V; Lau L; S ZD, 2020, 'DIPG-75. PRECISION MEDICINE FOR PAEDIATRIC HIGH-GRADE DIFFUSE MIDLINE GLIOMAS - RESULTS FROM THE ZERO CHILDHOOD CANCER COMPREHENSIVE PRECISION MEDICINE PROGRAM', in Neuro-Oncology, Oxford University Press (OUP), Vol. 22, pp. iii302 - iii302, http://dx.doi.org/10.1093/neuonc/noaa222.117

Haber M; Cowley MJ; Ekert P; Lau L; Mould E; Core ZPO; Core ZPDT; Gifford A; Lock RB; Marshall GM; Norris MD; O'Brien T; Quang DAK; Thomas D; Trahair T; Tucker K; Ziegler DS; Tyrrell V, 2020, 'Abstract SY09-02: Zero Childhood Cancer: A comprehensive precision medicine platform for children with high-risk cancer in Australia', in Cancer Research, American Association for Cancer Research (AACR), Vol. 80, pp. sy09-02-sy09-02, http://dx.doi.org/10.1158/1538-7445.am2020-sy09-02

Barahona P; Sherstyuk A; Cowley M; Ekert P; Kirk J; Khuong-Quang D-A; Kumar A; Lau L; Mayoh C; Marshall G; Moud E; O’Brien T; Pinese M; Thomas D; Tyrell V; Ziegler D; Haber M; Tucker K; Fuentes-Bolanos NA; Warby M, 2020, 'Abstract A03: Prevalence and spectrum of germline mutations in children with high-risk cancer', in Cancer Research, American Association for Cancer Research (AACR), Vol. 80, pp. a03 - a03, http://dx.doi.org/10.1158/1538-7445.pedca19-a03

Barahona P; Fletcher J; Fuentes-Bolanos N; Gauthier M-E; Haber M; Lock RB; Marshall GM; Mayoh C; Mould E; Nagabushan S; Norris M; O’Brien T; Sherstyuk A; Thomas D; Trahair T; Tucker K; Warby M; Wong M; Ziegler DS; Tyrrell VJ; Ekert P; Cowley MJ; Lau L; Quang D-AK, 2020, 'Abstract A52: Zero Childhood Cancer (ZERO): A comprehensive precision medicine platform for children with high-risk cancer', in Cancer Research, American Association for Cancer Research (AACR), Vol. 80, pp. a52 - a52, http://dx.doi.org/10.1158/1538-7445.pedca19-a52

Smith KM; Haire SO; Dong AK-Q; Markman B; Gan HK; Ekert PG; O'Byrne KJ; Millward M; Solomon BJ; Tran B; Scott CL; Kee D; McArthur GA; Fellowes A; Weerasuriya R; Lynch E; Martyn M; Gaff C; Fox SB; Desai J, 2020, 'Evaluating barriers to uptake of comprehensive genomic profiling (CGP) in advanced cancer patients (pts).', in JOURNAL OF CLINICAL ONCOLOGY, LIPPINCOTT WILLIAMS & WILKINS, ELECTR NETWORK, Vol. 38, presented at Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), ELECTR NETWORK, 29 May 2020 - 31 May 2020, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000560368301146&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Meyran D; Zhu J; Butler J; Macdonald S; Tantalo D; Thio N; Sek K; Ekert P; Kershaw M; Trapani J; Darcy P; Neeson P, 2020, '126 Early-phenotype Lewis Y CAR-T cells persist better in vivo and induce solid tumor regression in combination with anti-PD1', in Journal for ImmunoTherapy of Cancer, BMJ, Vol. 8, pp. a76 - a78, presented at Regular and young investigator award abstracts, http://dx.doi.org/10.1136/jitc-2020-sitc2020.0126

Fuentes-Bolanos N; Warby M; Barahona P; Sherstyuk A; Cowley M; Ekert P; Kirk J; Khuong-Quang DA; Amit K; Lau L; Mayoh C; Marshall G; Mould E; O'Brien TA; Pinese M; Thomas D; Tyrrell V; Ziegler D; Harber M; Tucker KM, 2019, 'Prevalence and Spectrum of Germline Mutations in Children with High-Risk Cancer', in PEDIATRIC BLOOD & CANCER, WILEY, Vol. 66, pp. S503 - S504, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000488458005160&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Quang DAK; Lau L; Cowley MJ; Ekert PG; Gifford AJ; Haber M; Lock R; Marshall G; Mayoh C; Mould E; Norris M; O'Brien T; Trahair T; Tyrrell V; Ziegler DS, 2019, 'Zero Childhood Cancer: A Comprehensive Precision Medicine Platform for Children and Adolescents with High-Risk Cancer', in PEDIATRIC BLOOD & CANCER, WILEY, Vol. 66, pp. S504 - S505, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000488458005162&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Smith K; O'Haire S; Dong-Anh K-Q; Markman B; Gan H; Ekert PG; O'Byrne K; Milward M; Solomon B; Tran B; Scott C; McArthur G; Kee D; Fellowes A; Xu H; Martyn M; Lynch E; Lorgelly P; Gaff C; Fox S; Desai J, 2019, 'iPREDICT: Incorporating complex profiling of patients to enrol onto molecularly directed cancer therapeutics. Preliminary results of the adult and paediatric', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY, Vol. 15, pp. 184 - 185, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000493438400299&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Haber M; Gamble L; Xiao L; Pandher R; Somers K; Murray J; Khan A; Yu D; Franshaw L; Burns MR; Tsoli M; Ehteda A; Cesare A; O'Connor A; Mussai F; de Santo C; Cheng P; Korotchkina L; Gurova K; Tyrrell V; Mould E; Lau L; Dong AKQ; Mayoh C; Arndt G; Barahona P; Failes T; Fletcher J; Fuentes-Bolanos N; Gauthier M-E; Gifford A; Grebert-Wade D; Kamili A; Kumar A; Nagabushan S; O'Brien T; Strong P; Sherstyuk A; Thomas D; Trahair T; Tucker K; Warby M; Wong M; Xie J; Evans K; Lock R; Chernova OB; Henderson M; Gudkov AV; Ekert P; Cowley MJ; Marshall GM; Ziegler DS; Norris MD, 2019, 'Molecular targeted therapies and precision medicine for children with neuroblastoma and other refractory malignancies', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CANADA, Montreal, Vol. 80, pp. 23 - 24, presented at AACR Special Conference on the Advances in Pediatric Cancer Research, CANADA, Montreal, 17 September 2019 - 20 September 2019, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000551367400013&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Barahona P; Sherstyuk A; Cowley M; Ekert P; Kirk J; Dong-Anh K-Q; Kumar A; Lau L; Mayoh C; Marshall G; Moud E; O'Brien T; Pinese M; Thomas D; Tyrell V; Ziegler D; Haber M; Tucker K; Fuentes-Bolanos NA; Warby M, 2019, 'Prevalence and spectrum of germline mutations in children with high-risk cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CANADA, Montreal, Vol. 80, pp. 42 - 43, presented at AACR Special Conference on the Advances in Pediatric Cancer Research, CANADA, Montreal, 17 September 2019 - 20 September 2019, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000551367400048&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Barahona P; Fletcher J; Fuentes-Bolanos N; Gauthier M-E; Haber M; Lock RB; Marshall GM; Mayoh C; Mould E; Nagabushan S; Norris M; O'Brien T; Sherstyuk A; Thomas D; Trahair T; Tucker K; Warby M; Wong M; Ziegler DS; Tyrrell VJ; Ekert P; Cowley MJ; Lau L; Quang D-AK, 2019, 'Zero Childhood Cancer (ZERO): A comprehensive precision medicine platform for children with highrisk cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CANADA, Montreal, Vol. 80, pp. 70 - 71, presented at AACR Special Conference on the Advances in Pediatric Cancer Research, CANADA, Montreal, 17 September 2019 - 20 September 2019, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000551367400096&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Tsoli M; Lau L; Barahona P; Mayoh C; Failes T; Wong M; Sherstyuk A; Gifford AJ; Kumar A; Mould E; Ung C; Tolhurst O; Gopalakrishnan A; Grebert-Wade D; Strong P; Trebilcock P; Lock R; Tyrrell V; Trahair T; Tucker K; Warby M; Arndt G; Norris M; Haber M; Marshall G; O'Brien T; Dong AKQ; Cowley M; Ekert P; Ziegler DS, 2019, 'RESULTS OF THE ZERO CHILDHOOD CANCER INTEGRA-TM PRECISION MEDICINE PLATFORM FOR PAEDIATRIC HIGH-RISK BRAIN TUMOURS', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, CA, San Francisco, Vol. 21, pp. 118 - 118, presented at 5th Biennial Conference of the Society-for-Neuro-Oncology on Pediatric Neuro-Oncology Basic and Translational Research, CA, San Francisco, 03 May 2019 - 04 May 2019, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000473243700229&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Meyran D; Zhu J; Buttler J; Tantalo D; Neeson M; Ekert P; Kershaw M; Trapani J; Darcy P; Neeson P, 2019, 'DEVELOPMENT OF NEXT GENERATION CAR'S TARGETING THE LEWIS Y ANTIGEN FOR THE TREATMENT OF CANCER', in CYTOTHERAPY, ELSEVIER SCI LTD, Vol. 21, pp. E15 - E15, http://dx.doi.org/10.1016/j.jcyt.2019.04.050

Tsoli M; Lau L; Barahona P; Mayoh C; Failes T; Wong M; Sherstyuk A; Gifford AJ; Kumar A; Mould E; Ung C; Tolhurst O; Gopalakrishnan A; Grebert-Wade D; Strong P; Trebilcock P; Lock R; Tyrrell V; Trahair T; Tucker K; Warby M; Arndt G; Norris M; Haber M; Marshall G; O’Brien T; Quang DAK; Cowley M; Ekert P; Ziegler DS, 2019, 'THER-23. RESULTS OF THE ZERO CHILDHOOD CANCER INTEGRATED PRECISION MEDICINE PLATFORM FOR PAEDIATRIC HIGH-RISK BRAIN TUMOURS', in Neuro-Oncology, Oxford University Press (OUP), Vol. 21, pp. ii118 - ii118, http://dx.doi.org/10.1093/neuonc/noz036.228

Mould EV; Lau L; Arndt G; Barahona P; Cowley MJ; Ekert P; Failes T; Fletcher J; Gifford A; Grebert-Wade D; Haber M; Kamili A; Kumar A; Lock RB; Marshall GM; Mayoh C; Norris M; O'Brien T; Quang DAK; Strong P; Sherstyuk A; Trahair T; Tsoli M; Tucker K; Warby M; Wong M; Xie J; Ziegler DS; Tyrrell V, 2019, 'Zero Childhood Cancer: A comprehensive precision medicine platform for children with high-risk cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Atlanta, GA, Vol. 79, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), Atlanta, GA, 29 March 2019 - 03 April 2019, http://dx.doi.org/10.1158/1538-7445.AM2019-3111

Ekert P; Wong M; Mould E; Gifford A; Norris M; Warby M; Trahair T; Tucker K; Ziegler D; Marshall G; O'Brien T; Haber M; Vanessa T; Cowley M, 2018, 'Zero Childhood Cancer: A Comprehensive Precision Medicine Platform for Children with High-Risk Cancer', in PEDIATRIC BLOOD & CANCER, WILEY, Vol. 65, pp. S643 - S644, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000445195005221&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Tsoli M; Wadham C; Pinese M; Failes T; Joshi S; Mould E; Yin J; Gayevski V; Kumar A; Kaplan W; Ekert P; Franshaw L; Gifford A; Weber M; Rodriguez M; Mayoh C; Cohn R; Arndt G; Lock R; Tyrrell V; Norris M; Haber M; Lau L; Quang DAK; Wong M; Trahair T; Marshall GM; Cowley MJ; Ziegler DS, 2018, 'Abstract LB-137: Integrated genomics: drug screening and personalized xenograft development approach to identify precision treatments for aggressive pediatric brain tumors', in Cancer Research, American Association for Cancer Research (AACR), Vol. 78, pp. lb-137-lb-137, http://dx.doi.org/10.1158/1538-7445.am2018-lb-137

Mould E; Lau L; Arndt G; Barahona P; Cowley M; Ekert P; Failes T; Fletcher J; Gifford A; Haber M; Kamili A; Kumar A; Lock R; Marshall G; Mayoh C; Mead S; Norris M; O'Brien T; Pinese M; Quang DAK; Trahair T; Tsoli M; Tucker K; Warby M; Wong M; Xie J; Ziegler D; Tyrrell V, 2018, 'Abstract LB-138: Zero Childhood Cancer: A comprehensive precision medicine platform for children with high-risk cancer', in Cancer Research, American Association for Cancer Research (AACR), Vol. 78, pp. lb-138-lb-138, http://dx.doi.org/10.1158/1538-7445.am2018-lb-138

Ziegler D; Tsoli M; Tyre V; Cohn R; Lau L; Cox M; Cowley M; Ekert P; Marshall G; Haber M, 2018, 'POTENT CLINICAL AND RADIOLOGICAL RESPONSE TO LAROTRECTINIB IN FIRST CASE OF TRK FUSION HIGH GRADE GLIOMA', in NEURO-ONCOLOGY, OXFORD UNIV PRESS INC, CO, Denver, Vol. 20, pp. 67 - 67, presented at 18th International Symposium on Pediatric Neuro-Oncology (ISPNO), CO, Denver, 30 June 2018 - 03 July 2018, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000438339000180&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Ziegler D; Tsoli M; Tyrell V; Cohn R; Lau L; Cox M; Cowley M; Ekert P; Marshall G; Haber M, 2018, 'EAPH-09. POTENT CLINICAL AND RADIOLOGICAL RESPONSE TO LAROTRECTINIB IN FIRST CASE OF TRK FUSION HIGH GRADE GLIOMA', in Neuro-Oncology, Oxford University Press (OUP), Vol. 20, pp. i67 - i67, http://dx.doi.org/10.1093/neuonc/noy059.178

Tyrrell V; Lau L; Arndt G; Barahona P; Cowley M; Ekert P; Failes T; Fletcher J; Gifford A; Haber M; Kamili A; Kumar A; Lock R; Marshall G; Mayoh C; Mead S; Mould E; O'Brien T; Pinese M; Khuong-Quang DA; Thomas D; Trahair T; Tsoli M; Tucker K; Wharby M; Wong M; Xie J; Ziegler D, 2018, 'Zero childhood cancer – Accelerating translation of experimental oncology: Better matching drug to target', in Pathology, Elsevier, Vol. 50, pp. s31, http://dx.doi.org/10.1016/j.pathol.2017.12.072

Lau L; Byrne J; Ekert PG; Failes T; Fellowes A; Fletcher J; Gifford A; Haber M; Kumar A; Lock R; Marshall G; McCowage GB; Mould E; Norris M; Trahair T; Tsoli M; Tyrrell V; Wadham C; Xie J; Ziegler DS, 2017, 'Pilot study of a comprehensive precision medicine platform for children with high-risk cancer.', in Journal of Clinical Oncology, American Society of Clinical Oncology (ASCO), Vol. 35, pp. 10539 - 10539, http://dx.doi.org/10.1200/jco.2017.35.15_suppl.10539

Preprints

Lonsdale A; Halman A; Brown L; Kosasih H; Ekert P; Oshlack A, 2022, Toblerone: detecting exon deletion events in cancer using RNA-seq, http://dx.doi.org/10.1101/2022.10.27.514132

Schmidt B; Cmero M; Ekert P; Davidson N; Oshlack A, 2021, Slinker: Visualising novel splicing events in RNA-Seq data, http://dx.doi.org/10.12688/f1000research.74836.1

Mayoh C; Gifford AJ; Terry R; Lau LM; Wong M; Rao P; Shai-Hee T; Saletta F; Khuong-Quang D-A; Qin V; Mateos M; Meyran D; Miller KE; Yuksel A; Mould EV; Bowen-James R; Govender D; Senapati A; Zhukova N; Omer N; Dholaria H; Alvaro F; Tapp H; Diamond Y; Pozza LD; Moore AS; Nicholls W; Gottardo NG; McCowage G; Hansford JR; Khaw S-L; Wood PJ; Catchpoole D; Cottrell CE; Mardis ER; Marshall GM; Tyrrell V; Haber M; Ziegler DS; Vittorio O; Trapani JA; Cowley MJ; Neeson PJ; Ekert PG, A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer, http://dx.doi.org/10.1101/2022.09.16.508179

Brown L; Tax G; Mateos PA; de Weck A; Foresto S; Robertson T; Jalud F; Ajuyah P; Barahona P; Mao J; Dolman ME; Wong M; Mayoh C; Cowley M; Lau L; Sadras T; Ekert P, A novel TRKB-activating internal tandem duplication characterizes a new mechanism of receptor tyrosine kinase activation, http://dx.doi.org/10.21203/rs.3.rs-5472548/v1

Schmidt B; Brown LM; Ryland GL; Lonsdale A; Kosasih HJ; Ludlow LE; Majewski IJ; Blombery P; Ekert PG; Davidson NM; Oshlack A, ALLSorts: a RNA-Seq classifier for B-Cell Acute Lymphoblastic Leukemia, http://dx.doi.org/10.1101/2021.08.01.454393

Brown LM; Mayoh C; Camper KA; Tax G; Mateos PA; Li W; El-Kamand S; Sullivan P; Bradley J; Thompson PI; Chen J; Sadras T; Salomon R; Wong M; Cowley MJ; de Weck A; Lau LMS; Manoharan N; Ekert PG, CBL mutations in pediatric solid and CNS tumors are a marker of receptor tyrosine kinase activation and a potential therapeutic target, http://dx.doi.org/10.64898/2025.12.02.691063

Schmidt BM; Davidson NM; Hawkins AD; Bartolo R; Majewski IJ; Ekert PG; Oshlack A, Clinker: visualising fusion genes detected in RNA-seq data, http://dx.doi.org/10.1101/218586

Maksimovic J; Streeton-Cook V; Grima CV; Hanna D; Tawfic N; Ludlow LE; Brown LM; Ekert PG; Alaei S; Yoannidis D; Kosasih HJ; White DL; Ahn A; Goel S; Khaw SL; Oshlack A; Sadras T, Closing the fusion-detection gap in single-cell RNA-seq with a scalable, probe-based workflow, http://dx.doi.org/10.64898/2026.08.26.747171

Fordham AM; Brown LM; Mayoh C; Salib A; Barger ZA; Wong M; Sian TCCLK; Xie J; Gunther K; Trebilcock P; Terry RL; Barahona P; Ajuyah P; Sherstyuk A; Avila A; Cadiz R; Perkins CM; Gifford AJ; Mao J; Zhao A; O’Regan LP; Gorgels D; Lau LM; Ziegler DS; Haber M; Tyrrell V; Lock RB; Cowley MJ; Nicholls W; Daly RJ; Ekert PG; Fleuren ED, Comprehensive multi-platform tyrosine kinase profiling reveals novel actionable FGFR aberrations across pediatric and AYA sarcomas, http://dx.doi.org/10.1101/2023.07.19.548825

Kan WL; Dhagat U; Hercus TR; Kaufmann KB; Nero TL; Zeng AGX; Toubia J; Barry EF; Broughton SE; Gomez GA; Dottore M; Cheung Tung Shing KS; Thomas D; Benard B; Simpson KJ; Schoof E; Goodall GJ; Begley CG; Ekert PG; Tvorogov D; D'Andrea RJ; Dick JE; Parker MW; Lopez A, Distinct Assemblies of Heterodimeric Cytokine Receptors Govern Stemness Programs in Leukemia, http://dx.doi.org/10.2139/ssrn.3707264

Mayoh C; Barahona P; Lin A; Cui L; Ajuyah P; Altekoester A; Lau LM; Khuong-Quang D-A; Sullivan P; Senapati A; Nagabushan S; Sullivan A; Omer N; Moore AS; Nicholls W; Endersby R; Gottardo NG; McCowage G; Pozza LD; Hansford JR; Khaw S-L; Wood PJ; Trahair TN; Marshall GM; Ziegler DS; Tyrrell V; Haber M; Wong M; Ekert PG; Cowley MJ, Expanding the utility of transcriptome analysis for mutation detection in high-risk childhood precision oncology, http://dx.doi.org/10.1101/2025.06.25.661445

Sullivan AJ; Khuong-Quang D-A; Villani A; Wong-Erasmus M; Trinder S; Lau LMS; Barahona P; Altekoester A-K; Rumford M; Dias K; Mayoh C; Fuentes-Bolanos NA; Courtney EK; El-Kamand S; Cui L; Lin A; Davidson S; Yuki KE; Sanders N; Staunton J; Jessop S; Sriharan S; Alvaro F; Anazodo A; Bhatia K; Campbell M; Foresto S; Gottardo NG; Kirby M; Khaw SL; Manoharan N; McCowage G; Moore AS; Nicholls W; O’Connor M; Padhye B; Ryan AL; Super L; Wood PJ; Davies J; D’Arcy C; Gifford AJ; Rodriguez M; Tucker KM; Pinese M; Ekert PG; Haber M; Tyrrell V; Trahair TN; Marshall GM; Shlien A; Cowley MJ; Ziegler DS, High clinical utility of comprehensive multi-omic molecular profiling of rare and hard-to-diagnose pediatric tumors, http://dx.doi.org/10.21203/rs.3.rs-10108527/v1

Sullivan AJ; Khuong-Quang D-A; Villani A; Wong-Erasmus M; Trinder S; Lau LMS; Barahona P; Altekoester A-K; Rumford M; Dias K; Mayoh C; Fuentes-Bolanos NA; Courtney EK; El-Kamand S; Cui L; Lin A; Davidson S; Yuki KE; Sanders N; Staunton J; Jessop S; Sriharan S; Alvaro F; Anazodo A; Bhatia K; Campbell M; Foresto S; Gottardo NG; Kirby M; Khaw SL; Manoharan N; McCowage G; Moore AS; Nicholls W; O’Connor M; Padhye B; Ryan AL; Super L; Wood PJ; Davies J; D’Arcy C; Gifford AJ; Rodriguez M; Tucker KM; Pinese M; Ekert PG; Haber M; Tyrrell V; Trahair TN; Marshall GM; Shlien A; Cowley MJ; Ziegler DS, High clinical utility of comprehensive multi-omic molecular profiling of rare and hard-to-diagnose pediatric tumors, http://dx.doi.org/10.64898/2026.07.25.26358936

Fuentes-Bolanos NA; Courtney E; Mayoh C; Warby M; Lau LMS; Wong-Erasmus M; Khuong-Quang D-A; Barahona P; Padhye B; El-Kamand S; Nunag S; Ajuyah P; Sherstyuk A; Altekoester A-K; Sullivan A; Poplawski N; Kiraly-Borri C; O’Sullivan S; Marfan H; Alli R; Curnow L; Bhatia K; Anazodo A; Trahair TN; Mateos M; Hansford JR; Dholaria H; Josephi-Taylor S; Moore AS; Nicholls W; Gottardo NG; Downie P; Khaw S-L; Tapp H; McCowage G; Dalla-Pozza L; Alvaro F; Wood PJ; Tyrrell V; Haber M; Cowley MJ; Ekert PG; Marshall GM; Kirk J; Tucker K; Pinese M; Ziegler DS, Integrated germline and somatic molecular profiling to detect cancer predisposition has a high clinical impact in poor-prognosis paediatric cancer, http://dx.doi.org/10.1101/2024.08.08.24311493

Davidson NM; Chen Y; Sadras T; Ryland GL; Blombery P; Ekert PG; Göke J; Oshlack A, JAFFAL: Detecting fusion genes with long read transcriptome sequencing, http://dx.doi.org/10.1101/2021.04.26.441398

Cmero M; Schmidt B; Majewski IJ; Ekert PG; Oshlack A; Davidson NM, MINTIE: identifying novel structural and splice variants in transcriptomes using RNA-seq data, http://dx.doi.org/10.1101/2020.06.03.131532

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