By Conjoint Professor Steven krilis

Journal articles

Yong A; Pennings G; Wong C; Javadzadegan A; Brieger D; Lowe H; Qi M; Behnia M; Krilis S; Kritharides L, 2013, 'Intracoronary upregulation of platelet extracellular matrix metalloproteinase inducer (CD147) in coronary disease', International Journal of Cardiology, 166, pp. 716 - 721, http://dx.doi.org/10.1016/j.ijcard.2011.11.093

Giannakopoulos B; Krilis S, 2013, 'The Pathogenesis of the Antiphospholipid Syndrome', New England Journal of Medicine, 368, pp. 1033 - 1044

Giannakopoulos B; Gao L; Qi M; Wong JW; Yu D; Vlachoyiannopoulos P; Moutsopoulos HM; Atsumi T; Koike T; Hogg PJ; Qi JC; Krilis S, 2012, 'Factor XI is a substrate for oxidoreductases: Enhanced activation of reduced FXI and its role in antiphospholipid syndrome thrombosis.', Journal of Autoimmunity, 39, pp. 121 - 129, http://dx.doi.org/10.1016/j.jaut.2012.05.005

Mirarabshahii P; Abdelatti A; Krilis S, 2012, 'Post-translational oxidative modification of â2-glycoprotein I and its role in the pathophysiology of the antiphospholipid syndrome.', Autoimmunity Reviews, 11, pp. 779 - 780, http://dx.doi.org/10.1016/j.autrev.2011.12.007

Adachi R; Krilis S; Nigrovic P; Hamilton MJ; Chung K; Thakurdas SM; Boyce JA; Anderson P; Stevens RL, 2012, 'Ras guanine nucleotide releasing protein-4 (RasGRP4) involvement in experimental arthritis and colitis.', The Journal of Biological Chemistry, 287, pp. 20047 - 20055, http://dx.doi.org/10.1074/jbc.M112.360388

Ioannou Y; Krilis SA, 2011, 'Laboratory Testing for Antiphospholipid Syndrome', , pp. 985 - 1000, http://dx.doi.org/10.1016/B978-0-12-374994-9.10052-X

Krilis S; Passam F; Giannakopoulos B; Mirarabshahi P, 2011, 'Molecular pathophysiology of the antiphospholipid syndrome: the role of oxidative posttranslational modification of beta 2 glycoprotein I', JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 9, pp. 715 - 715, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000208992803015&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Hamilton MJ; Sinnamon MJ; Lyng GD; Glickman JN; Wang X; Xing W; Krilis S; Blumberg RS; Adachi R; Lee DM; Stevens RL, 2011, 'Essential role for mast cell tryptase in acute experimental colitis.', Proceedings of the National Academy of Sciences of the United States of America, 108, pp. 290 - 295, http://dx.doi.org/10.1073/pnas.1005758108

Ruiz-irastorza G; Cuadrado MJ; Brey R; Crowther M; Derksen R; Erkan D; Krilis S; Machin S; Pengo V; Pierangeli S; Tektonidou M; Khamashta MA, 2011, 'Evidence-based recommendations for the prevention and long-term management of thrombosis in antiphospholipid antibody-positive patients: report of a task force at the 13th International Congress on antiphospholipid antibodies.', Lupus, 20, pp. 206 - 218, http://dx.doi.org/10.1177/0961203310395803

Yong A; Pennings GJ; Chang M; Hamzah A; Chung T; Qi M; Brieger D; Behnia M; Krilis S; Ng MK; Lowe HC; Kritharides L, 2011, 'Intracoronary shear-related up-regulation of platelet P-selectin and platelet monocyte aggregation despite the use of aspirin and clopidogral', Blood, 117, pp. 11 - 20, http://dx.doi.org/10.1182/blood-2010-04-278812

Giannakopoulos B; Mirarabshahi P; Krilis S, 2011, 'New insights into the biology and pathobiology of beta2-glycoprotein I.', Current Rheumatology Reports, 13, pp. 90 - 95, http://dx.doi.org/10.1007/s11926-010-0151-9

Passam F; Rahgozar S; Qi M; Raftery MJ; Wong JWH; Tanaka K; Ioannou Y; Zhang JY; Gemmell R; Qi JC; Giannakopoulos B; Hughes WE; Hogg PJ; Krilis S; Qi J, 2011, 'Redox control of â2-glycoprotein I-von Willebrand factor interaction by thioredoxin-1.', Journal of Thrombosis and Haemostasis, 8, pp. 1754 - 1762, http://dx.doi.org/10.1111/j.1538-7836.2010.03944.x

Ioannou Y; Zhang JY; Passam FH; Rahgozar S; Qi JC; Giannakopoulos B; Qi M; Yu P; Yu DM; Hogg PJ; Krilis SA, 2010, 'Naturally occurring free thiols within β2-glycoprotein I in vivo: Nitrosylation, redox modification by endothelial cells, and regulation of oxidative stress-induced cell injury', Blood, 116, pp. 1961 - 1970, http://dx.doi.org/10.1182/blood-2009-04-215335

Passam F; Rahgozar S; Qi M; Raftery MJ; Wong J; Tanaka K; Ioannou Y; Zhang JY; Gemmell R; Qi JC; Giannakopoulos B; Hughes WE; Hogg PJ; Krilis S, 2010, 'Beta 2 glycoprotein I is a substrate of thiol oxidoreductases', Blood, 116, pp. 1995 - 1997, http://bloodjournal.hematologylibrary.org/cgi/content/citation/116/11/1995

Passam F; Qi JC; Tanaka K; Matthaei K; Krilis S, 2010, 'In vivo modulation of angiogenesis by beta 2 glycoprotein I.', Journal of Autoimmunity, 35, pp. 232 - 240

Figtree M; Miyakis S; Stenos J; Graves S; Botham S; Ferson MJ; Krilis S, 2010, 'Q fever cholecystitis in an unvaccinated butcher diagnosed by gallbladder plymerase chain reaction', Vector - Borne and Zoonotic Diseases, 10, pp. 421 - 423, http://dx.doi.org/10.1089/vbz.2008.0209

Figtree M; Konecny P; Jennings Z; Goh C; Krilis S; Miyakis S, 2010, 'Risk Stratification and outcome of Cellulitis admitted to hospital', Journal of Infection, 60, pp. 431 - 439

Figtree MC; Miyakis S; Tanaka K; Martin L; Konecny P; Krilis S, 2009, 'Dapsone hypersensitivity syndrome causing disseminated intravascular coagulation', BMJ Case Reports, http://dx.doi.org/10.1136/bcr.11.2008.1257

Giannakopoulos B; Krilis S, 2009, 'How I treat the antiphospholipid syndrome', Blood, 114, pp. 2020 - 2030

Krilis S; Giannakopoulos B; Passam F; Ioannou Y, 2009, 'How we diagnose the antiphospholipid syndrome', Blood, 113, pp. 985 - 994

Reed J; Giannakopoulos B; Jackson M; Krilis S; Gordon T, 2009, 'Ro 60 functions as a receptor for β2-glycoprotein I on apoptotic cells', Arthritis Care & Research, 60, pp. 860 - 869

Krilis S; Reed J; Giannakopoulos B; Jackson M; Gordon T, 2009, 'Ro60 Functions as a receptor for B2-glycoprotein I on apoptotic cells', Arthritis Care & Research, 60, pp. 985 - 994

Figtree M; Miyakis S; Jennings Z; Goh C; Konecny P; Krilis S, 2008, 'Factors Influencing Outcome in Cellulitis Admitted to Hospital and the Role of the Infectious Disease Physician', INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 12, pp. E240 - E240, http://dx.doi.org/10.1016/j.ijid.2008.05.599

Rahgozar S; Giannakopoulos B; Yan X; Wei J; Jian CQ; Gemmell R; Krilis SA, 2008, 'Beta2-glycoprotein I protects thrombin from inhibition by heparin cofactor II: Potentiation of this effect in the presence of anti-β2-glycoprotein I autoantibodies', Arthritis and Rheumatism, 58, pp. 1146 - 1155, http://dx.doi.org/10.1002/art.23387

Yu P; Passam F; Yu D; Denyer GS; Krilis S, 2008, 'beta 2-glycoprotein I inhibits vascular endothelial growth factor and basic fibroblast growth factor induced angiogenesis through its amino terminal domain', Journal of Thrombosis and Haemostasis, 6, pp. 1215 - 1223, http://dx.doi.org/10.1111/j.1538-7836.2008.03000.x

Krilis S; Rahgozar S; Giannakopoulos B; Qi JC; Gemmell R; Yan X; Wei J, 2008, 'Beta2- Glycoprotein I Protects Thrombin from Inhibition by Heparin Cofactor II', Arthritis Care & Research, 58, pp. 1146 - 1155

Krilis S, 2008, 'The antiphospholipid syndrome: molecular and diagnostic aspects', INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY, 30, pp. 18 - 19

Katsoulotos GP; Qi M; Qi JC; Tanaka K; Hughes WE; Molloy T; Adachi R; Stevens RL; Krilis S, 2008, 'The Diacylglcerol-dependent translocation of ras guanine nucleotide -releasing protein 4 inside a human mast cell line results in substantional phenotypic changes ,including expressions of interluken 13 recepter a2', The Journal of Biological Chemistry, 283, pp. 1610 - 1621

Rahgozar S; Yang Q; Giannakopoulos B; Yan X; Miyakis S; Krilis SA, 2007, 'Beta2-glycoprotein I binds thrombin via exosite I and exosite II: Anti-β2-glycoprotein I antibodies potentiate the inhibitory effect of β2-glycoprotein I on thrombin-mediated factor XIa generation', Arthritis and Rheumatism, 56, pp. 605 - 613, http://dx.doi.org/10.1002/art.22367

Giannakopoulos B; Shi T; Yan XK; Yu P; Berndt MC; Andrew R; Rivera J; Iverson GM; Cockerill KA; Linnik MD; Krilis S, 2007, 'Anti-beta(2)-glycoprotein I antibodies in complex with beta(2)-glycoprotein I can activate platelets via glycoprotein Ib-IX-V', Clinical and Experimental Rheumatology, 25, pp. 159 - 160

Krilis S, 2007, 'APL targets and mediated effects: PL-binding proteins B2GPI', Clinical and Experimental Rheumatology, 25, pp. 123 - 123

Rahgozar S; Yang Q; Giannakopoulos B; Yan XK; Miyakis S; Krilis S, 2007, 'Beta(2)-glycoprotein I binds thrombin via exosite I and exosite II Anti-beta(2)-glycoprotein I antibodies potentiate the inhibitory effect of beta(2)-glycoprotein I on thrombin-mediated factor XIa generation', Arthritis Care & Research, 56, pp. 605 - 613

Giannakopoulos B; Passam F; Rahgozar S; Krilis S, 2007, 'Current concepts on the pathogenesis of the antiphospholipid syndrome', Blood, 109, pp. 422 - 430

Katsoulotos GP; Tanaka K; Molloy TJ; Stevens RL; Krilis S, 2007, 'Ras guanine nucleotide releasing protein 4 (RasGRP4) dependent pathways and genes that reversibly control the development, phenotype, and function of human mast cells (MCs)', Journal of Allergy and Clinical Immunology, 119, pp. S50 - S50

Shi T; Giannakopoulos B; Yan X; Yu P; Berndt MC; Andrews RK; Rivera J; Iverson GM; Cockerill KA; Linnik MD; Krilis SA, 2006, 'Anti-β2-glycoprotein I antibodies in complex with β2-glycoprotein I can activate platelets in a dysregulated manner via glycoprotein Ib-IX-V', Arthritis and Rheumatism, 54, pp. 2558 - 2567, http://dx.doi.org/10.1002/art.21968

Shi T; Giannakopoulos B; Yan XK; Yu P; Berndt MC; Andrews RK; Rivera J; Iverson M; Cockerill KA; Linnik MD; Krilis S, 2006, 'Anti-Beta2-Glycoprotein I Antibodies in Complex With Beta2-Glycoprotein I Can Activate Platelets in a Dysregulated Manner Via Glycoprotein Ib-IX-V', Arthritis Care & Research, 54, pp. 2558 - 2567

Qi J; Wang JQ; Mandadi S; Tanaka K; Roufogalis BD; Madigan MC; Lai K; Yan F; Chong BH; Stevens RL; Krilis S, 2006, 'Human and mouse mast cells use the Tetraspanin CD9 as an alternate Interleukin 16 receptor', Blood, 107, pp. 135 - 142

Miyakis S; Lockshin M; Atsumi T; Branch D; Brey R; Cervera R; Derksen R; Tincani A; Vlachoyiannopoulos P; Krilis S, 2006, 'International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS)', Journal of Thrombosis and Haemostasis, 4, pp. 295 - 306

Miyakis S; Lockshin M; Atsumi T; Branch D; Brey R; Cervera R; Derksen R; De Groot P; Koike T; Meroni PL; Reber G; Shoenfeld Y; Tincani A; Vlachoyiannopoulos P; Krilis S, 2006, 'International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS)', Journal of Thrombosis and Haemostasis, 4, pp. 295 - 306

Kordjian N; Donaldson A; Murrell DF; Krilis S, 2005, 'A case of desquamating rash associated with methadone use', Medical Journal of Australia, 182, pp. 76 - 77

Shi T; Giannakopoulos B; Iverson M; Cockerill KA; Linnik MD; Krilis S, 2005, 'Domain V of B2-Glycoprotein I Binds Factor XI/XIa and Is Cleaved of Lys317-Thr318', The Journal of Biological Chemistry, 280, pp. 907 - 912

Cai H; Song C; Lim IG; Krilis S; Geczy C; McNeil HP, 2005, 'Importance of C-Reactive Protein in Regulating Monocyte Tissue Factor Expresion in Patients with Inflammatory Rhumatic Diseases', The Journal of Rheumatology, 32, pp. 1224 - 1231

Andreson D; Donaldson A; Choo L; Knox A; Klaassen M; Ursic CM; Vonthethoff LW; Krilis S; Konecny P, 2005, 'Multifocal cutaneous mucormycosis complicating polymicrobial wound infections in a tsunami survivor from Sri Lanka', Lancet, 365, pp. 876 - 878

Di Simone N; Raschi E; Testoni C; Castellani R; D Asta M; Shi T; Krilis S; Caruso A; Luigi MP, 2005, 'Pathogenic role of anTi-beta 2-glycoprotein I in antiphospholipid-associated with fetal loss: characterisation of beta 2-glycoprotein I binding to trophoblast cells and functional effects of anti-beta 2-gylprotein I antiobodies in vitro', Annals of the Rheumatic Diseases, 64, pp. 462 - 467

Yasuda S; Morokawa N; Wong GW; Rossi A; Madhusudhan MS; Sali A; Askew YS; Adachi R; Silverman GA; Krilis S; Stevens RL, 2005, 'Urokinase-type plasminogen activator is a preferred substrate of the human epithelium serine protease tryptase /PRSS22', Blood, 105, pp. 3893 - 3901

Ho LH; Ruffin RE; Murgia C; Li LX; Krilis SA; Zalewski PD, 2004, 'Labile zinc and zinc transporter ZnT₄ in mast cell granules:: Role in regulation NF-KB translocation', JOURNAL OF IMMUNOLOGY, 172, pp. 7750 - 7760, http://dx.doi.org/10.4049/jimmunol.172.12.7750

Shi T; Iverson GM; Qi JC; Cockerill KA; Linnik MD; Konecny P; Krilis SA, 2004, 'β2-Glycoprotein I binds factor XI and inhibits its activation by thrombin and factor XIIa: Loss of inhibition by clipped β2-glycoprotein I', Proceedings of the National Academy of Sciences of the United States of America, 101, pp. 3939 - 3944, http://dx.doi.org/10.1073/pnas.0400281101

Passam FH; Krilis SA, 2004, 'Laboratory tests for the antiphospholipid syndrome: Current concepts', Pathology, 36, pp. 129 - 138, http://dx.doi.org/10.1080/00313020410001671966

Yang Q; Shi T; Cheyne B; Giannakopoulos B; Krilis S, 2004, 'Anti-beta(2) glycoprotein I antibodies potentiate the inhibitory effects of beta(2)glycoprotein I on the activation of FXI by FIIa: Effect of clipped beta(2) glycoprotein I', Thrombosis Research, 114, pp. 608 - 608

Bester C; Shi T; Iverson GM; Cockerill KA; Linnik MD; Konecny P; Krilis S, 2004, 'B-2-glycoprotein I binds factor XI by its C-terminal domain and inhibits its activation by thrombin and factor XIIA. Plasmin cleavage of B-2-glycoprotein I abolishes its inhibition of factor XIIA activation of factor XI', Thrombosis Research, 114, pp. 608 - 609

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