By Dr Alexander Malcolm Macmillan

Book Chapters

Pandzic E; Whan R; Macmillan A, 2022, 'Rapid FLIM Measurement of Membrane Tension Probe Flipper-TR', in Membrane Lipids: Methods and Protocols, pp. 257 - 283, http://dx.doi.org/10.1007/978-1-0716-1843-1_20

Pandzic E; Whan R; Macmillan A, 2021, 'Rapid FLIM Measurement of Membrane Tension Probe Flipper-TR', in Cranfield CG (ed.), Membrane Lipids. Methods in Molecular Biology, Springer Protocols, Humana, New York, NY, pp. 1 - 300, http://dx.doi.org/10.1007/978-1-0716-1843-1_20

Carnell M; Macmillan A; Whan R, 2015, 'Fluorescence recovery after photobleaching (FRAP): Acquisition, analysis, and applications', in , pp. 255 - 271, http://dx.doi.org/10.1007/978-1-4939-1752-5_18

Macmillan A; Cranfield C; Martinac B, 2014, 'Fluorescence Methods for Monitoring Mechanosensitive Channels', in Handbook of Imaging in Biological Mechanics, CRC Press, pp. 425 - 432, http://dx.doi.org/10.1201/b17566-46

Macmillan A; Cranfield CG; Martinac B, 2014, 'Fluorescence methods for monitoring mechanosensitive channels', in Handbook of Imaging in Biological Mechanics, pp. 425 - 431, http://dx.doi.org/10.1201/b17566

Journal articles

Saddam Hussain M; Khetan R; Clulow AJ; Ganesan R; MacMillan A; Robinson N; Ahmed-Cox A; Krasowska M; Albrecht H; Blencowe A, 2024, 'Teaching an Old Dog New Tricks: A Global Approach to Enhancing the Cytotoxicity of Drug-Loaded, Non-responsive Micelles Using Oligoelectrolytes', ACS Applied Materials and Interfaces, 16, pp. 9736 - 9748, http://dx.doi.org/10.1021/acsami.3c16551

Wen H; Kordahl D; Kuschnerus IC; Reineck P; Macmillan A; Chang HC; Dwyer C; Chang SLY, 2023, 'Correlative Fluorescence and Transmission Electron Microscopy Assisted by 3D Machine Learning Reveals Thin Nanodiamonds Fluoresce Brighter', ACS Nano, 17, pp. 16491 - 16500, http://dx.doi.org/10.1021/acsnano.3c00857

Liang W; Noor MZM; Lewis W; Macmillan A; Zhang X; Tang R; Kochubei A; Wiley D; Haynes BS; Huang J, 2023, 'Design of an ocu-Metal-Organic Framework for a Photocatalysis Reaction', ChemPhotoChem, 7, http://dx.doi.org/10.1002/cptc.202300031

Zhang L; Cao C; Tay SS; Chen C; Macmillan A; Wen S; Jin D; McCarroll J; Stenzel MH, 2023, 'Exploring the Effect of Drug Loading on the Biological Fate of Polymer-Coated Solid Nanoparticles', Chemistry of Materials, 35, pp. 4471 - 4488, http://dx.doi.org/10.1021/acs.chemmater.3c00644

Ma Y; Macmillan A; Yang Y; Gaus K, 2022, 'Lifetime based axial contrast enable simple 3D-STED imaging', Methods and Applications in Fluorescence, 10, http://dx.doi.org/10.1088/2050-6120/ac5e10

Ahmed-Cox A; Macmillan AM; Pandzic E; Whan RM; Kavallaris M, 2022, 'Application of Rapid Fluorescence Lifetime Imaging Microscopy (RapidFLIM) to Examine Dynamics of Nanoparticle Uptake in Live Cells', Cells, 11, http://dx.doi.org/10.3390/cells11040642

Silva FRO; Lima NB; Bellini MH; Teixeira LFS; Du EY; Jamshidi N; Gooding J; Martin AD; Macmillan A; Marquis CP; Thordarson P, 2022, 'Lanthanide-based β-Tricalcium Phosphate Upconversion Nanoparticles as an Effective Theranostic Nonviral Vectors for Image-Guided Gene Therapy', Nanotheranostics, 6, pp. 306 - 321, http://dx.doi.org/10.7150/ntno.68789

Lowe LA; Kindt JT; Cranfield C; Cornell B; Macmillan A; Wang A, 2022, 'Subtle changes in pH affect the packing and robustness of fatty acid bilayers', Soft Matter, http://dx.doi.org/10.1039/d2sm00272h

An H; Richardson A; Rajasekariah P; Zhong L; Fernando BSM; Macmillan A; Klotzsch E; Bryant K; Kaakoush NO; Tedla N, 2021, 'Nuclear Leukocyte Immunoglobulin-like Receptor A3 Is Monomeric and Is Involved in Multiple Layers of Regulated Gene Expression and Translation', Journal of Proteome Research, 20, pp. 3078 - 3089, http://dx.doi.org/10.1021/acs.jproteome.0c00946

Eslami M; Zeglio E; Alosaimi G; Yan Y; Ruprai H; Macmillan A; Seidel J; Lauto A; Joukhdar H; Rnjak-Kovacina J; Mawad D, 2020, 'A One Step Procedure toward Conductive Suspensions of Liposome-Polyaniline Complexes', Macromolecular Bioscience, 20, http://dx.doi.org/10.1002/mabi.202000103

Ridone P; Pandzic E; Vassalli M; Cox CD; Macmillan A; Gottlieb PA; Martinac B, 2020, 'Disruption of membrane cholesterol organization impairs the activity of PIEZO1 channel clusters', Journal of General Physiology, 152, http://dx.doi.org/10.1085/jgp.201912515

Sitiwin E; Madigan MC; Gratton E; Cherepanoff S; Conway RM; Whan R; Macmillan A, 2019, 'Shedding light on melanins within in situ human eye melanocytes using 2-photon microscopy profiling techniques', Scientific Reports, 9, http://dx.doi.org/10.1038/s41598-019-54871-y

Cao C; Zhao J; Chen F; Lu M; Khine YY; Macmillan A; Garvey CJ; Stenzel MH, 2018, 'Drug-Induced Morphology Transition of Self-Assembled Glycopolymers: Insight into the Drug-Polymer Interaction', Chemistry of Materials, 30, pp. 5227 - 5236, http://dx.doi.org/10.1021/acs.chemmater.8b01882

Yasarapudi VB; Frazer L; Webb JEA; Gallaher JK; MacMillan A; Falber A; Thordarson P; Schmidt TW, 2018, 'Competing Energy Transfer Pathways in a Five-Chromophore Perylene Array', Journal of Physical Chemistry C, 122, pp. 13937 - 13943, http://dx.doi.org/10.1021/acs.jpcc.8b01084

Sagnella SM; Trieu J; Brahmbhatt H; MacDiarmid JA; MacMillan A; Whan RM; Fife CM; McCarroll JA; Gifford AJ; Ziegler DS; Kavallaris M, 2018, 'Targeted doxorubicin-loaded bacterially derived nano-cells for the treatment of neuroblastoma', Molecular Cancer Therapeutics, 17, pp. 1012 - 1023, http://dx.doi.org/10.1158/1535-7163.MCT-17-0738

Chen F; Li K; Hart-Smith G; Xu YD; Jiang Y; Lu H; Fok S; Macmillian A; Pandzic E; Stenzel M; Macmillan A, 2018, 'Light-sheet microscopy as a tool to understanding the behaviour of Polyion complex micelles for drug delivery', Chemical Communications, 54, pp. 12618 - 12621, http://dx.doi.org/10.1039/C8CC04986F

Yasarapudi VB; Frazer L; Davis NJLK; Booker EP; Macmillan A; Gallaher JK; Roberts D; Perrier S; Schmidt TW, 2018, 'Optimization of energy transfer in a polymer composite with perylene chromophores', Journal of Materials Chemistry C, 6, pp. 7333 - 7342, http://dx.doi.org/10.1039/c8tc02457j

Chua SW; Cornejo A; Van Eersel J; Stevens CH; Vaca I; Cueto M; Kassiou M; Gladbach A; Macmillan A; Lewis L; Whan R; Ittner LM, 2017, 'The Polyphenol Altenusin Inhibits in Vitro Fibrillization of Tau and Reduces Induced Tau Pathology in Primary Neurons', ACS Chemical Neuroscience, 8, pp. 743 - 751, http://dx.doi.org/10.1021/acschemneuro.6b00433

Ittner A; Chua SW; Bertz J; Volkerling A; van der Hoven J; Gladbach A; Przybyla M; Bi M; van Hummel A; Stevens CH; Ippati S; Suh LS; Macmillan A; Sutherland G; Kril JJ; Silva APG; Mackay JP; Poljak A; Delerue F; Ke YD; Ittner LM, 2017, 'Site-specific phosphorylation of tau inhibits amyloid-beta toxicity in Alzheimer's mice (vol 354, 904, 2016)', SCIENCE, 355, http://dx.doi.org/10.1126/science.aam9523

Ittner A; Chua SW; Bertz J; Volkerling A; Van Der Hoven J; Gladbach A; Przybyla M; Bi M; Van Hummel A; Stevens CH; Ippati S; Suh LS; Macmillan A; Sutherland G; Kril JJ; Silva APG; Mackay J; Poljak A; Delerue F; Ke YD; Ittner LM, 2016, 'Site-specific phosphorylation of tau inhibits amyloid-β toxicity in Alzheimer's mice', Science, 354, pp. 904 - 908, http://dx.doi.org/10.1126/science.aah6205

Chandrakanthan V; Yeola A; Kwan JC; Oliver RA; Qiao Q; Kang YC; Zarzour P; Beck D; Boelen L; Unnikrishnan A; Villanueva JE; Nunez AC; Knezevic K; Palu C; Nasrallah R; Carnell M; Macmillan A; Whan R; Yu Y; Hardy P; Grey ST; Gladbach A; Delerue F; Ittner L; Mobbs R; Walkley CR; Purton LE; Ward RL; Wong JWH; Hesson LB; Walsh W; Pimanda JE, 2016, 'Pdgf-ab and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cells', Proceedings of the National Academy of Sciences of the United States of America, 113, pp. E2306 - E2315, http://dx.doi.org/10.1073/pnas.1518244113

Constantine M; Liew CK; Lo V; MacMillan A; Cranfield CG; Sunde M; Whan R; Graham RM; Martinac B, 2016, 'Heterologously-expressed and Liposome-reconstituted Human Transient Receptor Potential Melastatin 4 Channel (TRPM4) is a Functional Tetramer', Scientific Reports, 6, http://dx.doi.org/10.1038/srep19352

Sevimli S; Sagnella S; Macmillan A; Whan R; Kavallaris M; Bulmus V; Davis TP, 2015, 'The endocytic pathway and therapeutic efficiency of doxorubicin conjugated cholesterol-derived polymers', Biomaterials Science, 3, pp. 323 - 335, http://dx.doi.org/10.1039/c4bm00224e

Carnell M; Macmillan A; Whan R, 2015, 'Fluorescence recovery after photobleaching (FRAP): Acquisition, analysis, and applications', Methods in Molecular Biology, 1232, pp. 255 - 271, http://dx.doi.org/10.1007/978-1-4939-1752-5_18

Li Y; Duong HTT; Laurent S; Macmillan A; Whan RM; Elst LV; Muller RN; Hu J; Lowe A; Boyer C; Davis TP, 2015, 'Nanoparticles based on star polymers as theranostic vectors: Endosomal-triggered drug release combined with mri sensitivity', Advanced Healthcare Materials, 4, pp. 148 - 156, http://dx.doi.org/10.1002/adhm.201400164

Yaffe Y; Hugger I; Yassaf IN; Shepshelovitch J; Sklan EH; Elkabetz Y; Yeheskel A; Pasmanik-Chor M; Benzing C; Macmillan A; Gaus K; Eshed-Eisenbach Y; Peles E; Hirschberg K, 2015, 'The myelin proteolipid plasmolipin forms oligomers and induces liquid-ordered membranes in the Golgi complex', Journal of Cell Science, 128, pp. 2293 - 2302, http://dx.doi.org/10.1242/jcs.166249

Pasquier E; Tuset MP; Sinnappan S; Carnell M; Macmillan A; Kavallaris M, 2015, 'γ-Actin plays a key role in endothelial cell motility and neovessel maintenance', Vascular Cell, 7, http://dx.doi.org/10.1186/s13221-014-0027-2

Chang T; Lord MS; Bergmann B; MacMillan A; Stenzel MH, 2014, 'Size effects of self-assembled block copolymer spherical micelles and vesicles on cellular uptake in human colon carcinoma cells', Journal of Materials Chemistry B, 2, pp. 2883 - 2891, http://dx.doi.org/10.1039/c3tb21751e

Sagnella SM; Hien D; MacMillan A; Boyer C; Whan R; McCarroll JA; Davis TP; Kavallaris M; Duong H, 2014, 'Dextran-Based Doxorubicin Nanocarriers with Improved Tumor Penetration', BIOMACROMOLECULES, 15, pp. 262 - 275, http://dx.doi.org/10.1021/bm401526d

Salvemini IL; Gau DM; Reid J; Bagatolli LA; Macmillan A; Moens PDJ, 2014, 'Low PIP2 molar fractions induce nanometer size clustering in giant unilamellar vesicles', Chemistry and Physics of Lipids, 177, pp. 51 - 63, http://dx.doi.org/10.1016/j.chemphyslip.2013.11.003

Dunn AE; Dunn DJ; Macmillan A; Whan R; Stait-Gardner T; Price WS; Lim M; Boyer C, 2014, 'Spatial and temporal control of drug release through pH and alternating magnetic field induced breakage of Schiff base bonds', Polymer Chemistry, 5, pp. 3311 - 3315, http://dx.doi.org/10.1039/C4PY00150H

Basuki JS; Duong HTT; Macmillan A; Erlich RB; Esser L; Akerfeldt MC; Whan RM; Kavallaris M; Boyer C; Davis TP, 2013, 'Using Fluorescence Lifetime Imaging Microscopy to Monitor Theranostic Nanoparticle Uptake and Intracellular Doxorubicin Release', ACS NANO, 7, pp. 10175 - 10189, http://dx.doi.org/10.1021/nn404407g

Basuki JS; Duong HTT; Boyer C; MacMillan A; Whan R; Davis TP, 2013, 'Polymer-grafted, nonfouling, magnetic nanoparticles designed to selectively store and release molecules via ionic interactions', Macromolecules, 46, pp. 7043 - 7054, http://dx.doi.org/10.1021/ma401171d

Boyer CA; Kavallaris M; Whan R; Macmillan A, 2013, 'Functionalizing biodegradable dextran scaffolds using living radical polymerization: New versatile nanoparticles for the delivery of therapeutic molecules', Molecular Pharmaceutics, 9, pp. 3046 - 3061, http://dx.doi.org/10.1021/mp300144y

Boris M; Battle A; Nomura T; Constantine M; Cranfield C, 2012, 'Differential effects of lipids and lyso-lipids on the mechanosensitivity of the mechanosensitive channels MscL and MscS', Proceedings of the National Academy of Sciences of the United States of America, 109, pp. 8770 - 8775, http://dx.doi.org/10.1073/pnas.1200051109

Karolin J; Pánek D; MacMillan A; Rolinski O; Birch D, 2009, 'Fluorescence biosensing in nanopores.', Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, pp. 4154 - 4157

MacMillan AM; Panek D; McGuinness CD; Pickup JC; Graham D; Smith WE; Birch DJS; Karolin J, 2009, 'Improved biocompatibility of protein encapsulation in sol-gel materials', Journal of Sol-Gel Science and Technology, 49, pp. 380 - 384, http://dx.doi.org/10.1007/s10971-008-1883-0

McGuinness CD; MacMillan AM; Karolin J; Smith WE; Graham D; Pickup JC; Birch DJS, 2007, 'Single molecule level detection of allophycocyanin by surface enhanced resonance Raman scattering', Analyst, 132, pp. 633 - 634, http://dx.doi.org/10.1039/b706409h

McGuinness CD; Macmillan AM; Sagoo K; McLoskey D; Birch DJS, 2006, 'Excitation of fluorescence decay using a 265 nm pulsed light-emitting diode: Evidence for aqueous phenylalanine rotamers', Applied Physics Letters, 89, http://dx.doi.org/10.1063/1.2245441

Conference Papers

Sitiwin E; Madigan M; Jager M; Conway R; Cherepanoff S; Macmillan A, 2017, 'Application of label-free 2-photon fluorescence lifetime imaging microscopy to measure endogenous melanin profiles in human eye melanocytes, naevus and melanoma cells', in ACTA OPHTHALMOLOGICA, WILEY, http://dx.doi.org/10.1111/j.1755-3768.2017.03345

Bowden Q; MacMillan A; Rosenkranz T; Bocking T, 2014, 'Utilising Fluorescence Microscopy to Visualise the Dynamics and Interactions of Molecular Chaperones and alpha-Synuclein', in BIOPHYSICAL JOURNAL, CELL PRESS, CA, San Francisco, pp. 492A - 492A, presented at 58th Annual Meeting of the Biophysical-Society, CA, San Francisco, 15 February 2014 - 19 February 2014, http://dx.doi.org/10.1016/j.bpj.2016.11.2664

Cranfield CG; Deplazes E; MacMillan A; Owen D; Nomura T; Constantine M; Corry B; Martinac B, 2012, 'Clustering of the Mechanosensitive Ion Channels of Large and Small Conductance MscL and MscS - a FRET-Flim Study', in BIOPHYSICAL JOURNAL, CELL PRESS, CA, San Diego, pp. 120A - 120A, presented at 56th Annual Meeting of the Biophysical-Society, CA, San Diego, 25 February 2012 - 29 February 2012, http://dx.doi.org/10.1016/j.bpj.2011.11.674

Karolin J; Pánek D; MacMillan A; Rolinski O; Birch D, 2009, 'Fluorescence biosensing in nanopores', in Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009, pp. 4154 - 4157, http://dx.doi.org/10.1109/IEMBS.2009.5333940

Macmillan AM; McGuinness CD; Sagoo K; McLoskey D; Pickup JC; Birch DJS, 2008, 'Effect of pH on aqueous phenylalanine studied using a 265-nm pulsed light-emitting diode', in Annals of the New York Academy of Sciences, pp. 300 - 304, http://dx.doi.org/10.1196/annals.1430.056

Sutter JU; Macmillan AM; Birch DJS; Rolinski OJ, 2008, 'Toward single-metal-ion sensing by Förster resonance energy transfer', in Annals of the New York Academy of Sciences, pp. 62 - 67, http://dx.doi.org/10.1196/annals.1430.037

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