By Dr Alexander Malcolm Macmillan

Journal articles

Farazi S; Raveendran R; MacMillan A; Hillyer JT; Chapman R; Stenzel MH, 2026, 'FRET-Based Investigation of the Dynamics of Peptide-Folded Single Chain Nanoparticles Inside Cancer Cells', Macromolecular Rapid Communications, 47, http://dx.doi.org/10.1002/marc.202500167

Saputera WH; Yaasir RK; Pardede REB; Saputro AG; Mahyuddin MH; Hongo K; Satriyatama A; Gunawan D; Sun K; Macmillan A; Luong QT; Wibowo S; Arutanti O; Arif AF; Sasongko D; Devianto H, 2026, 'Turning Waste into Value: Photocatalytic Conversion of Methane to Methanol Using NiO/TiO2 Catalyst Derived from Spent Ni–Cd Batteries', Chemsuschem, 19, http://dx.doi.org/10.1002/cssc.70738

Yang Y; Ma Y; Macmillan A; Tilley R; Gooding JJ, 2025, 'Electrochemical fluorescence modulation enables simultaneous multicolour imaging', Nature Photonics, 19, pp. 718 - 724, http://dx.doi.org/10.1038/s41566-025-01672-7

Zhang D; Tsounis C; Peng L; Yin H; Hussain F; Carnell M; Macmillan A; Chu D; Amal R; Han Z, 2024, 'Nitrogen-doped vertical graphene for highly efficient hydrogen peroxide electrosynthesis in acidic environment', Chemical Engineering Journal, 496, http://dx.doi.org/10.1016/j.cej.2024.154221

Fu L; Bridges CA; Kim HN; Ding C; Bao Hou NC; Yeow J; Fok S; Macmillan A; Sterling JD; Baker SM; Lord MS, 2024, 'Cationic Polysaccharides Bind to the Endothelial Cell Surface Extracellular Matrix Involving Heparan Sulfate', Biomacromolecules, 25, pp. 3850 - 3862, http://dx.doi.org/10.1021/acs.biomac.4c00477

Saddam Hussain M; Khetan R; Clulow AJ; Ganesan R; MacMillan A; Robinson N; Ahmed-Cox A; Krasowska M; Albrecht H; Blencowe A, 2024, 'Teaching an Old Dog New Tricks: A Global Approach to Enhancing the Cytotoxicity of Drug-Loaded, Non-responsive Micelles Using Oligoelectrolytes', ACS Applied Materials and Interfaces, 16, pp. 9736 - 9748, http://dx.doi.org/10.1021/acsami.3c16551

Wen H; Kordahl D; Kuschnerus IC; Reineck P; Macmillan A; Chang HC; Dwyer C; Chang SLY, 2023, 'Correlative Fluorescence and Transmission Electron Microscopy Assisted by 3D Machine Learning Reveals Thin Nanodiamonds Fluoresce Brighter', ACS Nano, 17, pp. 16491 - 16500, http://dx.doi.org/10.1021/acsnano.3c00857

Liang W; Noor MZM; Lewis W; Macmillan A; Zhang X; Tang R; Kochubei A; Wiley D; Haynes BS; Huang J, 2023, 'Design of an ocu-Metal-Organic Framework for a Photocatalysis Reaction', Chemphotochem, 7, http://dx.doi.org/10.1002/cptc.202300031

Zhang L; Cao C; Tay SS; Chen C; Macmillan A; Wen S; Jin D; McCarroll J; Stenzel MH, 2023, 'Exploring the Effect of Drug Loading on the Biological Fate of Polymer-Coated Solid Nanoparticles', Chemistry of Materials, 35, pp. 4471 - 4488, http://dx.doi.org/10.1021/acs.chemmater.3c00644

Ma Y; Macmillan A; Yang Y; Gaus K, 2022, 'Lifetime based axial contrast enable simple 3D-STED imaging', Methods and Applications in Fluorescence, 10, http://dx.doi.org/10.1088/2050-6120/ac5e10

Lowe LA; Kindt JT; Cranfield C; Cornell B; Macmillan A; Wang A, 2022, 'Subtle changes in pH affect the packing and robustness of fatty acid bilayers', Soft Matter, 18, pp. 3498 - 3504, http://dx.doi.org/10.1039/d2sm00272h

Ahmed-Cox A; Macmillan AM; Pandzic E; Whan RM; Kavallaris M, 2022, 'Application of Rapid Fluorescence Lifetime Imaging Microscopy (RapidFLIM) to Examine Dynamics of Nanoparticle Uptake in Live Cells', Cells, 11, http://dx.doi.org/10.3390/cells11040642

Silva FRO; Lima NB; Bellini MH; Teixeira LFS; Du EY; Jamshidi N; Gooding J; Martin AD; Macmillan A; Marquis CP; Thordarson P, 2022, 'Lanthanide-based β-Tricalcium Phosphate Upconversion Nanoparticles as an Effective Theranostic Nonviral Vectors for Image-Guided Gene Therapy', Nanotheranostics, 6, pp. 306 - 321, http://dx.doi.org/10.7150/ntno.68789

An H; Richardson A; Rajasekariah P; Zhong L; Fernando BSM; Macmillan A; Klotzsch E; Bryant K; Kaakoush NO; Tedla N, 2021, 'Nuclear Leukocyte Immunoglobulin-like Receptor A3 Is Monomeric and Is Involved in Multiple Layers of Regulated Gene Expression and Translation', Journal of Proteome Research, 20, pp. 3078 - 3089, http://dx.doi.org/10.1021/acs.jproteome.0c00946

Eslami M; Zeglio E; Alosaimi G; Yan Y; Ruprai H; Macmillan A; Seidel J; Lauto A; Joukhdar H; Rnjak-Kovacina J; Mawad D, 2020, 'A One Step Procedure toward Conductive Suspensions of Liposome-Polyaniline Complexes', Macromolecular Bioscience, 20, http://dx.doi.org/10.1002/mabi.202000103

Ridone P; Pandzic E; Vassalli M; Cox CD; Macmillan A; Gottlieb PA; Martinac B, 2020, 'Disruption of membrane cholesterol organization impairs the activity of PIEZO1 channel clusters', Journal of General Physiology, 152, http://dx.doi.org/10.1085/jgp.201912515

Sitiwin E; Madigan MC; Gratton E; Cherepanoff S; Conway RM; Whan R; Macmillan A, 2019, 'Shedding light on melanins within in situ human eye melanocytes using 2-photon microscopy profiling techniques', Scientific Reports, 9, http://dx.doi.org/10.1038/s41598-019-54871-y

Cao C; Zhao J; Chen F; Lu M; Khine YY; Macmillan A; Garvey CJ; Stenzel MH, 2018, 'Drug-Induced Morphology Transition of Self-Assembled Glycopolymers: Insight into the Drug-Polymer Interaction', Chemistry of Materials, 30, pp. 5227 - 5236, http://dx.doi.org/10.1021/acs.chemmater.8b01882

Yasarapudi VB; Frazer L; Webb JEA; Gallaher JK; MacMillan A; Falber A; Thordarson P; Schmidt TW, 2018, 'Competing Energy Transfer Pathways in a Five-Chromophore Perylene Array', Journal of Physical Chemistry C, 122, pp. 13937 - 13943, http://dx.doi.org/10.1021/acs.jpcc.8b01084

Sagnella SM; Trieu J; Brahmbhatt H; MacDiarmid JA; MacMillan A; Whan RM; Fife CM; McCarroll JA; Gifford AJ; Ziegler DS; Kavallaris M, 2018, 'Targeted doxorubicin-loaded bacterially derived nano-cells for the treatment of neuroblastoma', Molecular Cancer Therapeutics, 17, pp. 1012 - 1023, http://dx.doi.org/10.1158/1535-7163.MCT-17-0738

Chen F; Li K; Hart-Smith G; Xu YD; Jiang Y; Lu H; Fok S; Macmillian A; Pandzic E; Stenzel M; Macmillan A, 2018, 'Light-sheet microscopy as a tool to understanding the behaviour of Polyion complex micelles for drug delivery', Chemical Communications, 54, pp. 12618 - 12621, http://dx.doi.org/10.1039/C8CC04986F

Yasarapudi VB; Frazer L; Davis NJLK; Booker EP; Macmillan A; Gallaher JK; Roberts D; Perrier S; Schmidt TW, 2018, 'Optimization of energy transfer in a polymer composite with perylene chromophores', Journal of Materials Chemistry C, 6, pp. 7333 - 7342, http://dx.doi.org/10.1039/c8tc02457j

Chua SW; Cornejo A; Van Eersel J; Stevens CH; Vaca I; Cueto M; Kassiou M; Gladbach A; Macmillan A; Lewis L; Whan R; Ittner LM, 2017, 'The Polyphenol Altenusin Inhibits in Vitro Fibrillization of Tau and Reduces Induced Tau Pathology in Primary Neurons', ACS Chemical Neuroscience, 8, pp. 743 - 751, http://dx.doi.org/10.1021/acschemneuro.6b00433

, 2017, 'Erratum for the Report “Site-specific phosphorylation of tau inhibits amyloid-β toxicity in Alzheimer’s mice” by A. Ittner, S. W. Chua, J. Bertz, A. Volkerling, J. van der Hoven, A. Gladbach, M. Przybyla, M. Bi, A. van Hummel, C. H. Stevens, S. Ippati, L. S. Suh, A. Macmillan, G. Sutherland, J. J. Kril, A. P. G. Silva, J. P. Mackay, A. Poljak, F. Delerue, Y. D. Ke, L. M. Ittner', Science, 355, pp. eaam9523, http://dx.doi.org/10.1126/science.aam9523

Ittner A; Chua SW; Bertz J; Volkerling A; Van Der Hoven J; Gladbach A; Przybyla M; Bi M; Van Hummel A; Stevens CH; Ippati S; Suh LS; Macmillan A; Sutherland G; Kril JJ; Silva APG; Mackay J; Poljak A; Delerue F; Ke YD; Ittner LM, 2016, 'Site-specific phosphorylation of tau inhibits amyloid-β toxicity in Alzheimer's mice', Science, 354, pp. 904 - 908, http://dx.doi.org/10.1126/science.aah6205

Chandrakanthan V; Yeola A; Kwan JC; Oliver RA; Qiao Q; Kang YC; Zarzour P; Beck D; Boelen L; Unnikrishnan A; Villanueva JE; Nunez AC; Knezevic K; Palu C; Nasrallah R; Carnell M; Macmillan A; Whan R; Yu Y; Hardy P; Grey ST; Gladbach A; Delerue F; Ittner L; Mobbs R; Walkley CR; Purton LE; Ward RL; Wong JWH; Hesson LB; Walsh W; Pimanda JE, 2016, 'Pdgf-ab and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cells', Proceedings of the National Academy of Sciences of the United States of America, 113, pp. E2306 - E2315, http://dx.doi.org/10.1073/pnas.1518244113

Constantine M; Liew CK; Lo V; MacMillan A; Cranfield CG; Sunde M; Whan R; Graham RM; Martinac B, 2016, 'Heterologously-expressed and Liposome-reconstituted Human Transient Receptor Potential Melastatin 4 Channel (TRPM4) is a Functional Tetramer', Scientific Reports, 6, http://dx.doi.org/10.1038/srep19352

Sevimli S; Sagnella S; Macmillan A; Whan R; Kavallaris M; Bulmus V; Davis TP, 2015, 'The endocytic pathway and therapeutic efficiency of doxorubicin conjugated cholesterol-derived polymers', Biomaterials Science, 3, pp. 323 - 335, http://dx.doi.org/10.1039/c4bm00224e

Carnell M; Macmillan A; Whan R, 2015, 'Fluorescence recovery after photobleaching (FRAP): Acquisition, analysis, and applications', Methods in Molecular Biology, 1232, pp. 255 - 271, http://dx.doi.org/10.1007/978-1-4939-1752-5_18

Li Y; Duong HTT; Laurent S; Macmillan A; Whan RM; Elst LV; Muller RN; Hu J; Lowe A; Boyer C; Davis TP, 2015, 'Nanoparticles based on star polymers as theranostic vectors: Endosomal-triggered drug release combined with mri sensitivity', Advanced Healthcare Materials, 4, pp. 148 - 156, http://dx.doi.org/10.1002/adhm.201400164

Yaffe Y; Hugger I; Yassaf IN; Shepshelovitch J; Sklan EH; Elkabetz Y; Yeheskel A; Pasmanik-Chor M; Benzing C; Macmillan A; Gaus K; Eshed-Eisenbach Y; Peles E; Hirschberg K, 2015, 'The myelin proteolipid plasmolipin forms oligomers and induces liquid-ordered membranes in the Golgi complex', Journal of Cell Science, 128, pp. 2293 - 2302, http://dx.doi.org/10.1242/jcs.166249

Pasquier E; Tuset MP; Sinnappan S; Carnell M; Macmillan A; Kavallaris M, 2015, 'γ-Actin plays a key role in endothelial cell motility and neovessel maintenance', Vascular Cell, 7, http://dx.doi.org/10.1186/s13221-014-0027-2

Chang T; Lord MS; Bergmann B; MacMillan A; Stenzel MH, 2014, 'Size effects of self-assembled block copolymer spherical micelles and vesicles on cellular uptake in human colon carcinoma cells', Journal of Materials Chemistry B, 2, pp. 2883 - 2891, http://dx.doi.org/10.1039/c3tb21751e

Sagnella SM; Hien D; MacMillan A; Boyer C; Whan R; McCarroll JA; Davis TP; Kavallaris M, 2014, 'Dextran-Based Doxorubicin Nanocarriers with Improved Tumor Penetration', BIOMACROMOLECULES, 15, pp. 262 - 275, http://dx.doi.org/10.1021/bm401526d

Salvemini IL; Gau DM; Reid J; Bagatolli LA; Macmillan A; Moens PDJ, 2014, 'Low PIP2 molar fractions induce nanometer size clustering in giant unilamellar vesicles', Chemistry and Physics of Lipids, 177, pp. 51 - 63, http://dx.doi.org/10.1016/j.chemphyslip.2013.11.003

Dunn AE; Dunn DJ; Macmillan A; Whan R; Stait-Gardner T; Price WS; Lim M; Boyer C, 2014, 'Spatial and temporal control of drug release through pH and alternating magnetic field induced breakage of Schiff base bonds', Polymer Chemistry, 5, pp. 3311 - 3315, http://dx.doi.org/10.1039/C4PY00150H

Basuki JS; Duong HTT; Macmillan A; Erlich RB; Esser L; Akerfeldt MC; Whan RM; Kavallaris M; Boyer C; Davis TP, 2013, 'Using Fluorescence Lifetime Imaging Microscopy to Monitor Theranostic Nanoparticle Uptake and Intracellular Doxorubicin Release', ACS NANO, 7, pp. 10175 - 10189, http://dx.doi.org/10.1021/nn404407g

Basuki JS; Duong HTT; Boyer C; MacMillan A; Whan R; Davis TP, 2013, 'Polymer-grafted, nonfouling, magnetic nanoparticles designed to selectively store and release molecules via ionic interactions', Macromolecules, 46, pp. 7043 - 7054, http://dx.doi.org/10.1021/ma401171d

Duong HTT; Hughes F; Sagnella S; Kavallaris M; MacMillan A; Whan R; Hook J; Davis TP; Boyer C, 2012, 'Functionalizing biodegradable dextran scaffolds using living radical polymerization: New versatile nanoparticles for the delivery of therapeutic molecules', Molecular Pharmaceutics, 9, pp. 3046 - 3061, http://dx.doi.org/10.1021/mp300144y

Boris M; Battle A; Nomura T; Constantine M; Cranfield C, 2012, 'Differential effects of lipids and lyso-lipids on the mechanosensitivity of the mechanosensitive channels MscL and MscS', Proceedings of the National Academy of Sciences of the United States of America, 109, pp. 8770 - 8775, http://dx.doi.org/10.1073/pnas.1200051109

Karolin J; Pánek D; MacMillan A; Rolinski O; Birch D, 2009, 'Fluorescence biosensing in nanopores.', Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, pp. 4154 - 4157

MacMillan AM; Panek D; McGuinness CD; Pickup JC; Graham D; Smith WE; Birch DJS; Karolin J, 2009, 'Improved biocompatibility of protein encapsulation in sol-gel materials', Journal of Sol Gel Science and Technology, 49, pp. 380 - 384, http://dx.doi.org/10.1007/s10971-008-1883-0

McGuinness CD; MacMillan AM; Karolin J; Smith WE; Graham D; Pickup JC; Birch DJS, 2007, 'Single molecule level detection of allophycocyanin by surface enhanced resonance Raman scattering', Analyst, 132, pp. 633 - 634, http://dx.doi.org/10.1039/b706409h

McGuinness CD; Macmillan AM; Sagoo K; McLoskey D; Birch DJS, 2006, 'Excitation of fluorescence decay using a 265 nm pulsed light-emitting diode: Evidence for aqueous phenylalanine rotamers', Applied Physics Letters, 89, http://dx.doi.org/10.1063/1.2245441

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