By Dr Anne Poljak

Journal articles

Chen DLT; Brown R; Liess C; Poljak A; Xu A; Zhang J; Trenell M; Jenkins A; Chisholm D; Samocha-Bonet D; Macefield VG; Greenfield JR; Chen D; Milliken S; Goodnow C, 2017, 'Muscle sympathetic nerve activity is associated with liver insulin sensitivity in obese non-diabetic men', Frontiers in Physiology, 8, pp. 101, http://dx.doi.org/10.3389/fphys.2017.00101

Wong MW; Braidy N; Poljak A; Pickford R; Thambisetty M; Sachdev PS, 2017, 'Dysregulation of lipids in Alzheimer's disease and their role as potential biomarkers', Alzheimers Dement, 13, pp. 810 - 827, http://dx.doi.org/10.1016/j.jalz.2017.01.008

Braidy N; Jugder B-E; Poljak A; Jayasena T; Nabavi SM; Sachdev P; Grant R, 2017, 'Molecular targets of Tannic Acid in Alzheimer’s disease', Curr Alzheimer Res, 14, http://dx.doi.org/10.2174/1567205014666170206163158

, 2017, 'Erratum for the Report “Site-specific phosphorylation of tau inhibits amyloid-β toxicity in Alzheimer’s mice” by A. Ittner, S. W. Chua, J. Bertz, A. Volkerling, J. van der Hoven, A. Gladbach, M. Przybyla, M. Bi, A. van Hummel, C. H. Stevens, S. Ippati, L. S. Suh, A. Macmillan, G. Sutherland, J. J. Kril, A. P. G. Silva, J. P. Mackay, A. Poljak, F. Delerue, Y. D. Ke, L. M. Ittner', Science, 355, pp. eaam9523, http://dx.doi.org/10.1126/science.aam9523

Poljak A; Sachdev PS, 2017, 'Plasma amyloid beta peptides: an Alzheimer’s conundrum or a more accessible Alzheimer’s biomarker?', Expert Review of Neurotherapeutics, 17, pp. 3 - 5, http://dx.doi.org/10.1080/14737175.2016.1217156

Lam T; McLean M; Bahl N; Poljak A; Ho KKY; Birzniece V, 2017, 'Testosterone prevents protein loss via the hepatic urea cycle', CLINICAL ENDOCRINOLOGY, 86, pp. 14 - 14, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000393453600038&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Wong MW; Braidy N; Poljak A; Sachdev PS, 2017, 'The application of lipidomics to biomarker research and pathomechanisms in Alzheimer's disease', Current Opinion in Psychiatry, 30, pp. 136 - 144, http://dx.doi.org/10.1097/YCO.0000000000000303

Liao Y; Williams TJ; Ye J; Charlesworth J; Burns BP; Poljak A; Raftery MJ; Cavicchioli R, 2016, 'Morphological and proteomic analysis of biofilms from the Antarctic archaeon, Halorubrum lacusprofundi', Scientific Reports, 6, pp. 37454, http://dx.doi.org/10.1038/srep37454

Ittner A; Chua SW; Bertz J; Volkerling A; Van Der Hoven J; Gladbach A; Przybyla M; Bi M; Van Hummel A; Stevens CH; Ippati S; Suh LS; Macmillan A; Sutherland G; Kril JJ; Silva APG; Mackay J; Poljak A; Delerue F; Ke YD; Ittner LM, 2016, 'Site-specific phosphorylation of tau inhibits amyloid-β toxicity in Alzheimer's mice', Science, 354, pp. 904 - 908, http://dx.doi.org/10.1126/science.aah6205

Jayasena T; Poljak A; Braidy N; Zhong L; Rowlands B; Muenchhoff J; Grant R; Smythe G; Teo C; Raftery M; Sachdev PS, 2016, 'Application of targeted mass spectrometry for the quantification of sirtuins in the central nervous system', Scientific Reports, 6, pp. 35391 - 35391, http://dx.doi.org/10.1038/srep35391

Liao Y; Williams TJ; Walsh JC; Ji M; Poljak A; Curmi PMG; Duggin IG; Cavicchioli R, 2016, 'Developing a genetic manipulation system for the Antarctic archaeon, Halorubrum lacusprofundi: Investigating acetamidase gene function', Scientific Reports, 6, pp. 34639, http://dx.doi.org/10.1038/srep34639

Muenchhoff J; Poljak A; Thalamuthu A; Gupta VB; Chatterjee P; Raftery M; Masters CL; Morris JC; Bateman RJ; Fagan AM; Martins RN; Sachdev PS, 2016, 'Changes in the plasma proteome at asymptomatic and symptomatic stages of autosomal dominant Alzheimer's disease', Scientific Reports, 6, pp. 29078 - 29078, http://dx.doi.org/10.1038/srep29078

Braidy N; Jugder BE; Poljak A; Jayasena T; Mansour H; Nabavi SM; Sachdev P; Grant R, 2016, 'Resveratrol as a potential therapeutic candidate for the treatment and management of alzheimer’s disease', Current Topics in Medicinal Chemistry, 16, pp. 1951 - 1960, http://dx.doi.org/10.2174/1568026616666160204121431

Mather KA; Thalamuthu A; Oldmeadow C; Song F; Armstrong NJ; Poljak A; Holliday EG; McEvoy M; Kwok JB; Assareh AA; Reppermund S; Kochan NA; Lee T; Ames D; Wright MJ; Trollor JN; Schofield PW; Brodaty H; Scott RJ; Schofield PR; Attia JR; Sachdev PS, 2016, 'Genome-wide significant results identified for plasma apolipoprotein H levels in middle-aged and older adults.', Sci Rep, 6, pp. 23675, http://dx.doi.org/10.1038/srep23675

Chen DL; Liess C; Poljak A; Xu A; Zhang J; Thoma C; Trenell M; Milner B; Jenkins AB; Chisholm DJ; Samocha-Bonet D; Greenfield JR, 2016, 'Erratum: Phenotypic Characterization of Insulin-Resistant and Insulin-Sensitive Obesity (Journal of Clinical Endocrinology and Metabolism 2015 100(11): (4082-4091)); doi: 10.1210/jc.2015-2712', Journal of Clinical Endocrinology and Metabolism, 101, pp. 757, http://dx.doi.org/10.1210/jc.2015-4260

Braidy N; Essa MM; Poljak A; Selvaraju S; Al-Adawi S; Manivasagm T; Thenmozhi AJ; Ooi L; Sachdev P; Guillemin GJ, 2016, 'Consumption of pomegranates improves synaptic function in a transgenic mice model of Alzheimer's disease', Oncotarget, 7, pp. 64589 - 64604, http://dx.doi.org/10.18632/oncotarget.10905

Yeung ACY; D'Agostino PM; Poljak A; McDonald J; Bligh MW; Waite TD; Neilan BA, 2016, 'Physiological and proteomic responses of continuous cultures of Microcystis aeruginosa PCC 7806 to changes in iron bioavailability and growth rate', Applied and Environmental Microbiology, 82, pp. 5918 - 5929, http://dx.doi.org/10.1128/AEM.01207-16

McGill M; Shum A; Poljak A; Tan T; Polly P, 2016, 'Cancer Cachexia Induced Changes in Sarcomeric and Energy Homeostasis: Proteomic Signatures in the Heart', Heart, Lung and Circulation, 25, pp. S99 - S100, http://dx.doi.org/10.1016/j.hlc.2016.06.236

Poljak A; Crawford JD; Smythe GA; Brodaty H; Slavin MJ; Kochan NA; Trollor JN; Wen W; Mather KA; Assareh AA; Ng PC; Sachdev PS, 2016, 'The Relationship Between Plasma Aβ Levels, Cognitive Function and Brain Volumetrics: Sydney Memory and Ageing Study.', Current Alzheimer research, 13, pp. 243 - 255, http://dx.doi.org/10.2174/1567205013666151218150202

Chen DL; Liess C; Poljak A; Xu A; Zhang J; Thoma C; Trenell M; Milner B; Jenkins AB; Chisholm DJ; Samocha-Bonet D; Greenfield JR, 2015, 'Phenotypic characterization of insulin-resistant and insulin-sensitive obesity', Journal of Clinical Endocrinology and Metabolism, 100, pp. 4082 - 4091, http://dx.doi.org/10.1210/jc.2015-2712

Braidy N; Poljak A; Grant R; Jayasena T; Mansour H; Chan-Ling T; Smythe G; Sachdev P; Guillemin GJ, 2015, 'Differential expression of sirtuins in the aging rat brain', Frontiers in Cellular Neuroscience, 9, pp. 167, http://dx.doi.org/10.3389/fncel.2015.00167

Braidy N; Poljak A; Jayasena T; Mansour H; Inestrosa NC; Sachdev PS, 2015, 'Accelerating Alzheimer's research through 'natural' animal models', Current Opinion in Psychiatry, 28, pp. 155 - 164, http://dx.doi.org/10.1097/YCO.0000000000000137

Ertan H; Cassel C; Verma A; Poljak A; Charlton T; Aldrich-Wright J; Omar SM; Siddiqui KS; Cavicchioli R, 2015, 'A new broad specificity alkaline metalloprotease from a Pseudomonas sp. isolated from refrigerated milk: Role of calcium in improving enzyme productivity', Journal of Molecular Catalysis B Enzymatic, 113, pp. 1 - 8, http://dx.doi.org/10.1016/j.molcatb.2014.12.010

Lazarus J; Mather KA; Armstrong NJ; Song F; Poljak A; Thalamuthu A; Lee T; Kochan NA; Brodaty H; Wright MJ; Ames D; Sachdev PS; Kwok JBJ, 2015, 'DNA methylation in the apolipoprotein-A1 gene is associated with episodic memory performance in healthy older individuals', Journal of Alzheimer's Disease, 44, pp. 175 - 182, http://dx.doi.org/10.3233/JAD-141314

Muenchhoff J; Poljak A; Song F; Raftery M; Brodaty H; Duncan M; McEvoy M; Attia J; Schofield PW; Sachdev PS, 2015, 'Plasma protein profiling of mild cognitive impairment and Alzheimer's disease across two independent cohorts', Journal of Alzheimer's Disease, 43, pp. 1355 - 1373, http://dx.doi.org/10.3233/JAD-141266

Jayasena T; Poljak A; Braidy N; Smythe G; Raftery M; Hill M; Brodaty H; Trollor J; Kochan N; Sachdev P, 2015, 'Upregulation of glycolytic enzymes, mitochondrial dysfunction and increased cytotoxicity in glial cells treated with Alzheimer's disease plasma.', PLoS One, 10, pp. e0116092, http://dx.doi.org/10.1371/journal.pone.0116092

Hou X; McMillan M; Coumans JVF; Poljak A; Raftery MJ; Pereg L, 2014, 'Cellular responses during morphological transformation in Azospirillum brasilense and its flcA knockout mutant', Plos One, 9, http://dx.doi.org/10.1371/journal.pone.0114435

Coumans JVF; Gau D; Poljak A; Wasinger V; Roy P; Moens PDJ, 2014, 'Profilin-1 overexpression in MDA-MB-231 breast cancer cells is associated with alterations in proteomics biomarkers of cell proliferation, survival, and motility as revealed by global proteomics analyses', OMICS A Journal of Integrative Biology, 18, pp. 778 - 791, http://dx.doi.org/10.1089/omi.2014.0075

Lee P; Birzniece V; Umpleby AM; Poljak A; Ho KKY, 2014, 'Formoterol, a Highly β2-Selective Agonist, Induces Gender-Dimorphic Whole Body Leucine Metabolism in Humans', Metabolism: Clinical and Experimental, http://dx.doi.org/10.1016/j.metabol.2014.12.005

Braidy N; Poljak A; Grant R; Jayasena T; Mansour H; Chan-Ling T; Guillemin GJ; Smythe G; Sachdev P, 2014, 'Mapping NAD+ metabolism in the brain of ageing Wistar rats: potential targets for influencing brain senescence', Biogerontology, 15, pp. 177 - 198, http://dx.doi.org/10.1007/s10522-013-9489-5

Coumans JVF; Gau D; Poljak A; Wasinger V; Roy P; Moens P, 2014, 'Green fluorescent protein expression triggers proteome changes in breast cancer cells', Experimental Cell Research, 320, pp. 33 - 45, http://dx.doi.org/10.1016/j.yexcr.2013.07.019

Braidy N; Poljak A; Marjo C; Rutlidge H; Rich A; Jayasena T; Inestrosa NC; Sachdev P, 2014, 'Metal and complementary molecular bioimaging in alzheimer's disease', Frontiers in Aging Neuroscience, 6, pp. 138, http://dx.doi.org/10.3389/fnagi.2014.00138

Curthoys NM; Freittag H; Connor A; Desouza M; Brettle M; Poljak A; Hall A; Hardeman E; Schevzov G; Gunning PW; Fath T, 2014, 'Tropomyosins induce neuritogenesis and determine neurite branching patterns in B35 neuroblastoma cells', Molecular and Cellular Neuroscience, 58, pp. 11 - 21, http://dx.doi.org/10.1016/j.mcn.2013.10.011

Song F; Poljak A; Kochan NA; Raftery M; Brodaty H; Smythe GA; Sachdev PS, 2014, 'Plasma protein profiling of Mild Cognitive Impairment and Alzheimer’s disease using iTRAQ quantitative proteomics', Proteome Science, 12, http://dx.doi.org/10.1186/1477-5956-12-5

Caplan GA; Poljak A; Hill MA; Hall R; MacLullich A; Raftery M; Tai J; Yan S, 2014, 'Quantitative Proteomics of Delirium Cerebrospinal Fluid', Translational Psychiatry, 4, pp. e477 - e477, http://dx.doi.org/10.1038/tp.2014.114

Siddiqui KS; Ertan H; Charlton T; Poljak A; Daud Khaled AK; Yang X; Marshall G; Cavicchioli R, 2014, 'Versatile peroxidase degradation of humic substances: Use of isothermal titration calorimetry to assess kinetics, and applications to industrial wastes', Journal of Biotechnology, 178, pp. 1 - 11, http://dx.doi.org/10.1016/j.jbiotec.2014.03.002

Petersons CJ; Mangelsdorf BL; Jenkins AB; Poljak A; Smith MD; Greenfield JR; Thompson CH; Burt MG, 2013, 'Effects of low-dose prednisolone on hepatic and peripheral insulin sensitivity, insulin secretion, and abdominal adiposity in patients with inflammatory rheumatologic disease', Diabetes Care, 36, pp. 2822 - 2829, http://dx.doi.org/10.2337/dc12-2617

Birzniece V; Umpleby MA; Poljak A; Handelsman DJ; Ho KKY, 2013, 'Oral low-dose testosterone administration induces whole-body protein anabolism in postmenopausal women: A novel liver-targeted therapy', European Journal of Endocrinology, 169, pp. 321 - 327, http://dx.doi.org/10.1530/EJE-13-0406

Ooi L; Sidhu K; Poljak A; Sutherland G; O’Connor MD; Sachdev P; Münch G, 2013, 'Induced pluripotent stem cells as tools for disease modelling and drug discovery in Alzheimer’s disease', Journal of Neural Transmission, 120, pp. 103 - 111, http://dx.doi.org/10.1007/s00702-012-0839-2

Jayasena T; Braidy N; Sachdev P; Poljak A; Smythe G; Münch G, 2013, 'The role of polyphenols in the modulation of sirtuins and other pathways involved in Alzheimer's disease', Ageing Research Reviews, 12, pp. 867 - 883, http://dx.doi.org/10.1016/j.arr.2013.06.003

Song F; Poljak A; Crawford J; Kochan NA; Wen W; Cameron B; Lux O; Brodaty H; Mather K; Smythe GA; Sachdev PS, 2012, 'Plasma Apolipoprotein Levels Are Associated with Cognitive Status and Decline in a Community Cohort of Older Individuals', PLoS ONE, 7, pp. e34078 - e34078, http://dx.doi.org/10.1371/journal.pone.0034078

Braidy N; Jayasena T; Poljak A; Sachdev PS, 2012, 'Sirtuins in cognitive ageing and Alzheimer's disease', Current Opinion in Psychiatry, 25, pp. 226 - 230, http://dx.doi.org/10.1097/yco.0b013e32835112c1

Braidy N; Guillemin GJ; Hussein M; Chan-Ling T; Poljak A; Grant RS, 2011, 'Age Related Changes in NAD+ Metabolism Oxidative Stress and Sirt1 Activity in Wistar Rats.', PLoS One, 6, pp. e19194, http://dx.doi.org/10.1371/journal.pone.0019194

Williams TJ; Lauro FM; Ertan H; Burg DW; Poljak A; Raftery MJ; Cavicchioli R, 2011, 'Defining the response of a microorganism to temperatures that span its complete growth temperature range (−2°C to 28°C) using multiplex quantitative proteomics', Environmental Microbiology, 13, pp. 2186 - 2203, http://dx.doi.org/10.1111/j.1462-2920.2011.02467.x

Song F; Poljak A; Valenzuela M; Mayeux R; Smythe GA; Sachdev PS, 2011, 'Meta-analysis of plasma amyloid-β levels in Alzheimer's disease.', Journal of Alzheimer's disease : JAD, 26, pp. 365 - 375, http://dx.doi.org/10.3233/jad-2011-101977

Song F; Poljak A; Jayasena T; Smythe G; Brodaty H; Kochan N; Sachdev P; Crawford J, 2011, 'P1‐115: Plasma apolipoproteins as biomarkers of mild cognitive impairment in a community‐based sample', Alzheimer's & Dementia, 7, pp. s146 - s146, http://dx.doi.org/10.1016/j.jalz.2011.05.394

Coumans JVF; Harvey J; Backhouse D; Poljak A; Raftery MJ; Nehl D; Katz ME; Pereg L, 2011, 'Proteomic assessment of host‐associated microevolution in the fungus Thielaviopsis basicola', Environmental Microbiology, 13, pp. 576 - 588, http://dx.doi.org/10.1111/j.1462-2920.2010.02358.x

Phillips PA; Yang L; Shulkes A; Vonlaufen A; Poljak A; Bustamante S; Warren A; Xu Z; Guilhaus M; Pirola R; Apte MV; Wilson JS, 2010, 'Pancreatic stellate cells produce acetylcholine and may play a role in pancreatic exocrine secretion.', Proc Natl Acad Sci U S A, 107, pp. 17397 - 17402, http://dx.doi.org/10.1073/pnas.1000359107

Lim YA; Rhein V; Baysang G; Meier F; Poljak A; Raftery MJ; Guilhaus M; Ittner LM; Eckert A; Götz J, 2010, 'Aβ and human amylin share a common toxicity pathway via mitochondrial dysfunction', Proteomics, 10, pp. 1621 - 1633, http://dx.doi.org/10.1002/pmic.200900651

Siddiqui KS; Poljak A; De Francisci D; Guerriero G; Pilak O; Burg D; Raftery MJ; Parkin DM; Trewhella J; Cavicchioli R, 2010, 'A chemically modified α-amylase with a molten-globule state has entropically driven enhanced thermal stability†', Protein Engineering, Design and Selection, 23, pp. 769 - 780, http://dx.doi.org/10.1093/protein/gzq051

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