By Dr Ashish Dhar Diwan

Journal articles

Chen X; Sandhu HS; Vargas Castillo J; Diwan AD, 2021, 'The association between pain scores and disc height change following discectomy surgery in lumbar disc herniation patients: a systematic review and meta-analysis', European Spine Journal, 30, pp. 3265 - 3277, http://dx.doi.org/10.1007/s00586-021-06891-4

Ong CS; Choy WJ; Phan K; Diwan A; Mobbs R, 2021, '843 Annular Closure Device for Disc Herniation: Meta-Analysis of Clinical Outcome and Complications', British Journal of Surgery, 108, http://dx.doi.org/10.1093/bjs/znab259.937

Tu J; Li W; Yang S; Yang P; Yan Q; Wang S; Lai K; Bai X; Wu C; Ding W; Cooper-White J; Diwan A; Yang C; Yang H; Zou J, 2021, 'Single-cell transcriptome profiling reveals multicellular ecosystem of nucleus pulposus during degeneration progression', , http://dx.doi.org/10.1101/2021.05.25.445620

Chen X; Hodges PW; James G; Diwan AD, 2021, 'Do markers of inflammation and/or muscle regeneration in lumbar multifidus muscle and fat differ between individuals with good or poor outcome following microdiscectomy for lumbar disc herniation?', Spine, 46, pp. 678 - 686, http://dx.doi.org/10.1097/BRS.0000000000003863

Cui H; Zhang J; Li Z; Chen F; Cui H; Du X; Liu H; Wang J; Diwan AD; Zheng Z, 2021, 'Growth differentiation factor-6 attenuates inflammatory and pain-related factors and degenerated disc-induced pain behaviors in rat model', Journal of Orthopaedic Research, 39, pp. 959 - 970, http://dx.doi.org/10.1002/jor.24793

Menounos S; Hansbro PM; Diwan AD; Das A, 2021, 'Pathophysiological Correlation between Cigarette Smoking and Amyotrophic Lateral Sclerosis', NeuroSci, 2, pp. 120 - 134, http://dx.doi.org/10.3390/neurosci2020008

Koremans FW; Chen X; Das A; Diwan AD, 2021, 'Changes in back pain scores after bariatric surgery in obese patients: A systematic review and meta-analysis', Journal of Clinical Medicine, 10, pp. 1443, http://dx.doi.org/10.3390/jcm10071443

Blumenthal S; Diwan AD, 2021, 'Correction to: Editorial (European Spine Journal, (2020), 29, 11, (2629-2630), 10.1007/s00586-020-06607-0)', European Spine Journal, 30, pp. 1085 - 1086, http://dx.doi.org/10.1007/s00586-020-06708-w

James G; Chen X; Diwan A; Hodges PW, 2021, 'Fat infiltration in the multifidus muscle is related to inflammatory cytokine expression in the muscle and epidural adipose tissue in individuals undergoing surgery for intervertebral disc herniation', European Spine Journal, 30, pp. 837 - 845, http://dx.doi.org/10.1007/s00586-020-06514-4

Tu J; Castillo JV; Das A; Diwan AD, 2021, 'Degenerative cervical myelopathy: Insights into its pathobiology and molecular mechanisms', Journal of Clinical Medicine, 10, pp. 1 - 28, http://dx.doi.org/10.3390/jcm10061214

Lapkin S; Ellwood L; Diwan A; Fernandez R, 2021, 'Reliability, validity, and responsiveness of multidimensional pain assessment tools used in postoperative adult patients: A systematic review of measurement properties', JBI Evidence Synthesis, 19, pp. 284 - 307, http://dx.doi.org/10.11124/JBISRIR-D-19-00407

MacDessi SJ; Cohen DA; Wood JA; Diwan AD; Harris IA, 2021, 'Does the Use of Intraoperative Pressure Sensors for Knee Balancing in Total Knee Arthroplasty Improve Clinical Outcomes? A Comparative Study With a Minimum Two-Year Follow-Up', Journal of Arthroplasty, 36, pp. 514 - 519, http://dx.doi.org/10.1016/j.arth.2020.08.025

MacDessi SJ; Wood JA; Diwan AD; Harris IA; Bhimani A; Burns AWR; Chen DB; Molnar RB; Mulford JS; Walker RM, 2021, 'Surgeon-defined assessment is a poor predictor of knee balance in total knee arthroplasty: a prospective, multicenter study', Knee Surgery, Sports Traumatology, Arthroscopy, 29, pp. 498 - 506, http://dx.doi.org/10.1007/s00167-020-05925-6

Tavakoli J; Geargeflia S; Tipper JL; Diwan AD, 2021, 'Magnetic resonance elastography: A non-invasive biomarker for low back pain studies', Biomedical Engineering Advances, 2, pp. 100014 - 100014, http://dx.doi.org/10.1016/j.bea.2021.100014

Hodgkinson T; Gilbert HTJ; Pandya T; Diwan AD; Hoyland JA; Richardson SM, 2020, 'Regenerative response of degenerate human nucleus pulposus cells to GDF6 stimulation', International Journal of Molecular Sciences, 21, pp. 1 - 14, http://dx.doi.org/10.3390/ijms21197143

Tavakoli J; Diwan AD; Tipper JL, 2020, 'The ultrastructural organization of elastic fibers at the interface of the nucleus and annulus of the intervertebral disk', Acta Biomaterialia, 114, pp. 323 - 332, http://dx.doi.org/10.1016/j.actbio.2020.07.021

Tavakoli J; Diwan AD; Tipper JL, 2020, 'Elastic fibers: The missing key to improve engineering concepts for reconstruction of the Nucleus Pulposus in the intervertebral disc', Acta Biomaterialia, 113, pp. 407 - 416, http://dx.doi.org/10.1016/j.actbio.2020.06.008

Tavakoli J; Diwan AD; Tipper JL, 2020, 'Advanced strategies for the regeneration of lumbar disc annulus fibrosus', International Journal of Molecular Sciences, 21, pp. 1 - 20, http://dx.doi.org/10.3390/ijms21144889

Chen X; Chamoli U; Vargas Castillo J; Ramakrishna VAS; Diwan AD, 2020, 'Complication rates of different discectomy techniques for symptomatic lumbar disc herniation: a systematic review and meta-analysis', European Spine Journal, 29, pp. 1752 - 1770, http://dx.doi.org/10.1007/s00586-020-06389-5

Ramakrishna VAS; Chamoli U; Rajan G; Mukhopadhyay SC; Prusty BG; Diwan AD, 2020, 'Smart orthopaedic implants: A targeted approach for continuous postoperative evaluation in the spine', Journal of Biomechanics, 104, http://dx.doi.org/10.1016/j.jbiomech.2020.109690

Zhang T; Ren X; Feng X; Diwan A; Luk KDK; Lu WW; Wong TM; Li C; Cheung JPY, 2020, 'Failure mechanisms of pedicle screws and cortical screws fixation under large displacement: A biomechanical and microstructural study based on a clinical case scenario', Journal of the Mechanical Behavior of Biomedical Materials, 104, http://dx.doi.org/10.1016/j.jmbbm.2020.103646

Chamoli U; Umali J; Kleuskens MWA; Chepurin D; Diwan AD, 2020, 'Morphological characteristics of the kangaroo lumbar intervertebral discs and comparison with other animal models used in spine research', European Spine Journal, 29, pp. 652 - 662, http://dx.doi.org/10.1007/s00586-019-06044-8

Zhang T; Zhu C; Lu Q; Liu J; Diwan A; Cheung JPY, 2020, 'A novel tool to provide predictable alignment data irrespective of source and image quality acquired on mobile phones: what engineers can offer clinicians', European Spine Journal, 29, pp. 387 - 395, http://dx.doi.org/10.1007/s00586-019-06264-y

Sritharan K; Chamoli U; Kuan J; Diwan AD, 2020, 'Assessment of degenerative cervical stenosis on T2-weighted MR imaging: sensitivity to change and reliability of mid-sagittal and axial plane metrics', Spinal Cord, 58, pp. 238 - 246, http://dx.doi.org/10.1038/s41393-019-0358-1

MacDessi SJ; Griffiths-Jones W; Chen DB; Griffiths-Jones S; Wood JA; Diwan AD; Harris IA, 2020, 'Restoring the constitutional alignment with a restrictive kinematic protocol improves quantitative soft-tissue balance in total knee arthroplasty: A randomized controlled trial', Bone and Joint Journal, 102, pp. 117 - 124, http://dx.doi.org/10.1302/0301-620X.102B1.BJJ-2019-0674.R2

Koremans F; Chen X; Das A; Diwan A, 2020, 'Changes in back pain scores after bariatric surgery in obese patients: A systematic review and meta-analysis', , http://dx.doi.org/10.1101/2020.08.25.20182022

Costa N; Ferreira ML; Setchell J; Makovey J; Dekroo T; Downie A; Diwan A; Koes B; Natvig B; Vicenzino B; Hunter D; Roseen EJ; Rasmussen-Barr E; Guillemin F; Hartvigsen J; Bennell K; Costa L; Macedo L; Pinheiro M; Underwood M; Van Tulder M; Johansson M; Enthoven P; Kent P; O'Sullivan P; Suri P; Genevay S; Hodges PW, 2019, 'A Definition of “Flare” in Low Back Pain: A Multiphase Process Involving Perspectives of Individuals With Low Back Pain and Expert Consensus', Journal of Pain, 20, pp. 1267 - 1275, http://dx.doi.org/10.1016/j.jpain.2019.03.009

Chepurin D; Chamoli U; Sheldrick K; Lapkin S; Scott D; Kuan J; Diwan AD, 2019, 'Bony stress in the lumbar spine is associated with intervertebral disc degeneration and low back pain: a retrospective case–control MRI study of patients under 25 years of age', European Spine Journal, 28, pp. 2470 - 2477, http://dx.doi.org/10.1007/s00586-019-06148-1

Chen X; Chamoli U; Lapkin S; Castillo JV; Diwan AD, 2019, 'Complication rates of different discectomy techniques for the treatment of lumbar disc herniation: a network meta-analysis', European Spine Journal, 28, pp. 2588 - 2601, http://dx.doi.org/10.1007/s00586-019-06142-7

Sheldrick K; Chamoli U; Masuda K; Miyazaki S; Kato K; Diwan AD, 2019, 'A novel magnetic resonance imaging postprocessing technique for the assessment of intervertebral disc degeneration—Correlation with histological grading in a rabbit disc degeneration model', JOR Spine, 2, pp. e1060, http://dx.doi.org/10.1002/jsp2.1060

Lapkin S; Fernandez R; Ellwood L; Diwan A, 2019, 'Reliability, validity and generalizability of multidimensional pain assessment tools used in postoperative adult patients: a systematic review protocol', JBI database of systematic reviews and implementation reports, 17, pp. 1334 - 1340, http://dx.doi.org/10.11124/JBISRIR-2017-003819

Sabnis AB; Chamoli U; Diwan AD, 2019, 'Answer to the Letter to the Editor of Miao Yu et al. concerning “Is L5-S1 motion segment different from the rest? A radiographic kinematic assessment of 72 patients with chronic low back pain” by AB Sabnis et al. (Eur. Spine J; 27(5):1127–1135)', European Spine Journal, 28, pp. 1249, http://dx.doi.org/10.1007/s00586-018-5675-0

MacDessi SJ; Bhimani A; Burns AWR; Chen DB; Leong AKL; Molnar RB; Mulford JS; Walker RM; Harris IA; Diwan A; Wood JA, 2019, 'Does soft tissue balancing using intraoperative pressure sensors improve clinical outcomes in total knee arthroplasty? A protocol of a multicentre randomised controlled trial', BMJ Open, 9, pp. e027812, http://dx.doi.org/10.1136/bmjopen-2018-027812

Miyazaki S; Diwan AD; Kato K; Cheng K; Bae WC; Sun Y; Yamada J; Muehleman C; Lenz ME; Inoue N; Sah RL; Kawakami M; Masuda K, 2019, 'Correction to: ISSLS PRIZE IN BASIC SCIENCE 2018: Growth differentiation factor-6 attenuated pro-inflammatory molecular changes in the rabbit anular-puncture model and degenerated disc-induced pain generation in the rat xenograft radiculopathy model (European Spine Journal, (2018), 27, 4, (739-751), 10.1007/s00586-018-5488-1)', European Spine Journal, 28, pp. 889, http://dx.doi.org/10.1007/s00586-019-05878-6

Hodgkinson T; Shen B; Diwan A; Hoyland JA; Richardson SM, 2019, 'Therapeutic potential of growth differentiation factors in the treatment of degenerative disc diseases', JOR Spine, 2, pp. e1045, http://dx.doi.org/10.1002/jsp2.1045

Bax DV; Yin Y; Kondyurin A; Diwan AD; Bhargav D; Weiss AS; Bilek MMM; McKenzie DR, 2018, 'Plasma processing of PDMS based spinal implants for covalent protein immobilization, cell attachment and spreading', Journal of Materials Science: Materials in Medicine, 29, http://dx.doi.org/10.1007/s10856-018-6181-y

Thorpe AA; Bach FC; Tryfonidou MA; Le Maitre CL; Mwale F; Diwan AD; Ito K, 2018, 'Leaping the hurdles in developing regenerative treatments for the intervertebral disc from preclinical to clinical', JOR Spine, 1, pp. e1027, http://dx.doi.org/10.1002/jsp2.1027

Choy WJ; Phan K; Diwan AD; Ong CS; Mobbs RJ, 2018, 'Annular closure device for disc herniation: Meta-analysis of clinical outcome and complications', BMC Musculoskeletal Disorders, 19, pp. 290, http://dx.doi.org/10.1186/s12891-018-2213-5

Ramakrishna VAS; Chamoli U; Viglione LL; Tsafnat N; Diwan AD, 2018, 'The Role of Sacral Slope in the Progression of a Bilateral Spondylolytic Defect at L5 to Spondylolisthesis: A Biomechanical Investigation Using Finite Element Analysis', Global Spine Journal, 8, pp. 460 - 470, http://dx.doi.org/10.1177/2192568217735802

Sabnis AB; Chamoli U; Diwan AD, 2018, 'Is L5–S1 motion segment different from the rest? A radiographic kinematic assessment of 72 patients with chronic low back pain', European Spine Journal, 27, pp. 1127 - 1135, http://dx.doi.org/10.1007/s00586-017-5400-4

Ramakrishna VAS; Chamoli U; Viglione LL; Tsafnat N; Diwan AD, 2018, 'Mild (not severe) disc degeneration is implicated in the progression of bilateral L5 spondylolysis to spondylolisthesis', BMC Musculoskeletal Disorders, 19, pp. 98, http://dx.doi.org/10.1186/s12891-018-2011-0

Miyazaki S; Diwan AD; Kato K; Cheng K; Bae WC; Sun Y; Yamada J; Muehleman C; Lenz ME; Inoue N; Sah RL; Kawakami M; Masuda K, 2018, 'ISSLS PRIZE IN BASIC SCIENCE 2018: Growth differentiation factor-6 attenuated pro-inflammatory molecular changes in the rabbit anular-puncture model and degenerated disc-induced pain generation in the rat xenograft radiculopathy model', European Spine Journal, 27, pp. 739 - 751, http://dx.doi.org/10.1007/s00586-018-5488-1

Martin JT; Gullbrand SE; Fields AJ; Purmessur D; Diwan AD; Oxland TR; Chiba K; Guilak F; Hoyland JA; Iatridis JC, 2018, 'Publication trends in spine research from 2007 to 2016: Comparison of the Orthopaedic Research Society Spine Section and the International Society for the Study of the Lumbar Spine', JOR Spine, 1, pp. e1006, http://dx.doi.org/10.1002/jsp2.1006

Richardson SM; Hodgkinson T; Wei A; Shen B; Diwan A; Hoyland J, 2018, 'Growth differentiation factor 6 promotes a healthy nucleus pulposus cell phenotype through smad and smad-independent signalling pathways', Osteoarthritis and Cartilage, 26, pp. S423 - S423, http://dx.doi.org/10.1016/j.joca.2018.02.817

Virk SS; Diwan A; Phillips FM; Sandhu H; Khan SN, 2017, 'What is the Rate of Revision Discectomies After Primary Discectomy on a National Scale?', Clinical Orthopaedics and Related Research, 475, pp. 2752 - 2762, http://dx.doi.org/10.1007/s11999-017-5467-6

Viglione LL; Chamoli U; Diwan AD, 2017, 'Is Stand-Alone Anterior Lumbar Interbody Fusion a Safe and Efficacious Treatment for Isthmic Spondylolisthesis of L5-S1?', Global Spine Journal, 7, pp. 587 - 595, http://dx.doi.org/10.1177/2192568217699210

Wei A; Shen B; Williams LA; Bhargav D; Yan F; Chong BH; Diwan AD, 2016, 'Expression and functional roles of estrogen receptor GPR30 in human intervertebral disc', Journal of Steroid Biochemistry and Molecular Biology, 158, pp. 46 - 55, http://dx.doi.org/10.1016/j.jsbmb.2016.01.012

Wei A; Shen B; Williams LA; Bhargav D; Gulati T; Fang Z; Pathmanandavel S; Diwan AD, 2016, 'Expression of growth differentiation factor 6 in the human developing fetal spine retreats from vertebral ossifying regions and is restricted to cartilaginous tissues', Journal of Orthopaedic Research, 34, pp. 279 - 289, http://dx.doi.org/10.1002/jor.22983

Gulati T; Chung SA; Wei AQ; Diwan AD, 2015, 'Localization of bone morphogenetic protein 13 in human intervertebral disc and its molecular and functional effects in vitro in 3D culture', Journal of Orthopaedic Research, 33, pp. 1769 - 1775, http://dx.doi.org/10.1002/jor.22965

Chamoli U; Korkusuz MH; Sabnis AB; Manolescu AR; Tsafnat N; Diwan AD, 2015, 'Global and segmental kinematic changes following sequential resection of posterior osteoligamentous structures in the lumbar spine: An in vitro biomechanical investigation using pure moment testing protocols', Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 229, pp. 812 - 821, http://dx.doi.org/10.1177/0954411915612503

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