By Dr Benjamin Lau

Journal articles

Lau BKF; Dillon O; Vinod SK; O'Brien RT; Reynolds T, 2024, 'Faster and lower dose imaging: evaluating adaptive, constant gantry velocity and angular separation in fast low-dose 4D cone beam CT imaging', Medical Physics, 51, pp. 1364 - 1382, http://dx.doi.org/10.1002/mp.16585

Winters BL; Lau BK; Vaughan CW, 2022, 'Cannabinoids and Opioids Differentially Target Extrinsic and Intrinsic GABAergic Inputs onto the Periaqueductal Grey Descending Pathway', Journal of Neuroscience, 42, pp. 7744 - 7756, http://dx.doi.org/10.1523/JNEUROSCI.0997-22.2022

Lau BKF; Reynolds T; Keall PJ; Sonke JJ; Vinod SK; Dillon O; O'Brien RT, 2022, 'Reducing 4DCBCT imaging dose and time: Exploring the limits of adaptive acquisition and motion compensated reconstruction', Physics in Medicine and Biology, 67, http://dx.doi.org/10.1088/1361-6560/ac55a4

O'Brien RT; Dillon O; Lau B; George A; Smith S; Wallis A; Sonke JJ; Keall PJ; Vinod SK, 2021, 'The first-in-human implementation of adaptive 4D cone beam CT for lung cancer radiotherapy: 4DCBCT in less time with less dose', Radiotherapy and Oncology, 161, pp. 29 - 34, http://dx.doi.org/10.1016/j.radonc.2021.05.021

Lau BKF; Reynolds T; Wallis A; Smith S; George A; Keall PJ; Sonke JJ; Vinod SK; Dillon O; O'Brien RT, 2021, 'Reducing 4DCBCT scan time and dose through motion compensated acquisition and reconstruction', Physics in Medicine and Biology, 66, http://dx.doi.org/10.1088/1361-6560/abebfb

Lau BK; Ambrose BP; Thomas CS; Qiao M; Borgland SL, 2020, 'Mu-opioids suppress gabaergic synaptic transmission onto orbitofrontal cortex pyramidal neurons with subregional selectivity', Journal of Neuroscience, 40, pp. 5894 - 5907, http://dx.doi.org/10.1523/JNEUROSCI.2049-19.2020

Lau BK; Winters BL; Vaughan CW, 2020, 'Opioid presynaptic disinhibition of the midbrain periaqueductal grey descending analgesic pathway', British Journal of Pharmacology, 177, pp. 2320 - 2332, http://dx.doi.org/10.1111/bph.14982

Konen LM; Wright AL; Royle GA; Morris GP; Lau BK; Seow PW; Zinn R; Milham LT; Vaughan CW; Vissel B, 2020, 'A new mouse line with reduced GluA2 Q/R site RNA editing exhibits loss of dendritic spines, hippocampal CA1-neuron loss, learning and memory impairments and NMDA receptor-independent seizure vulnerability', Molecular Brain, 13, http://dx.doi.org/10.1186/s13041-020-0545-1

Lau BK; Cota D; Cristino L; Borgland SL, 2017, 'Endocannabinoid modulation of homeostatic and non-homeostatic feeding circuits', Neuropharmacology, 124, pp. 38 - 51, http://dx.doi.org/10.1016/j.neuropharm.2017.05.033

Baimel C; Lau BK; Qiao M; Borgland SL, 2017, 'Projection-Target-Defined Effects of Orexin and Dynorphin on VTA Dopamine Neurons', Cell Reports, 18, pp. 1346 - 1355, http://dx.doi.org/10.1016/j.celrep.2017.01.030

Aubrey KR; Drew GM; Jeong HJ; Lau BK; Vaughan CW, 2017, 'Endocannabinoids control vesicle release mode at midbrain periaqueductal grey inhibitory synapses', Journal of Physiology, 595, pp. 165 - 178, http://dx.doi.org/10.1113/JP272292

Thompson JL; Yang J; Lau B; Liu S; Baimel C; Kerr LE; Liu F; Borgland SL, 2016, 'Age-dependent D1-D2 receptor coactivation in the lateral orbitofrontal cortex potentiates NMDA receptors and facilitates cognitive flexibility', Cerebral Cortex, 26, pp. 4524 - 4539, http://dx.doi.org/10.1093/cercor/bhv222

Wilson-Poe AR; Lau BK; Vaughan CW, 2015, 'Repeated morphine treatment alters cannabinoid modulation of GABAergic synaptic transmission within the rat periaqueductal grey', British Journal of Pharmacology, 172, pp. 681 - 690, http://dx.doi.org/10.1111/bph.12809

Lau BK; Drew GM; Mitchell VA; Vaughan CW, 2014, 'Endocannabinoid modulation by FAAH and monoacylglycerol lipase within the analgesic circuitry of the periaqueductal grey', British Journal of Pharmacology, 171, pp. 5225 - 5236, http://dx.doi.org/10.1111/bph.12839

Lau BK; Vaughan CW, 2014, 'Descending modulation of pain: The GABA disinhibition hypothesis of analgesia', Current Opinion in Neurobiology, 29, pp. 159 - 164, http://dx.doi.org/10.1016/j.conb.2014.07.010

Lau BK; Karim S; Goodchild AK; Vaughan CW; Drew GM, 2014, 'Menthol enhances phasic and tonic GABAA receptor-mediated currents in midbrain periaqueductal grey neurons', British Journal of Pharmacology, 171, pp. 2803 - 2813, http://dx.doi.org/10.1111/bph.12602

Lau BK; Vaughan CW, 2014, 'Targeting the endogenous cannabinoid system to treat neuropathic pain', Frontiers in Pharmacology, 5 MAR, http://dx.doi.org/10.3389/fphar.2014.00028

Drew GM; Lau BK; Vaughan CW, 2009, 'Substance P drives endocannabinoid-mediated disinhibition in a midbrain descending analgesic pathway', Journal of Neuroscience, 29, pp. 7220 - 7229, http://dx.doi.org/10.1523/JNEUROSCI.4362-08.2009

Lau BK; Vaughan CW, 2008, 'Muscarinic modulation of synaptic transmission via endocannabinoid signalling in the rat midbrain periaqueductal gray', Molecular Pharmacology, 74, pp. 1392 - 1398, http://dx.doi.org/10.1124/mol.108.045872

Preprints

Lau B; Ambrose B; Thomas C; Qiao M; Borgland S, 2020, Mu-opioids suppress GABAergic synaptic transmission onto orbitofrontal cortex pyramidal neurons with subregional selectivity, http://dx.doi.org/10.1101/2020.05.12.091678

Lau B; Murphy-Royal C; Kaur M; Qiao M; Bains J; Gordon G; Borgland S, 2020, Obesity-induced astrocyte dysfunction impairs heterosynaptic plasticity in the orbitofrontal cortex, http://dx.doi.org/10.1101/2020.05.01.073205

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