By Dr Daryan Kempe

Journal articles

English K; Kwan R; Holz LE; McGuffog C; Krol JMM; Kempe D; Kaisho T; Heath WR; Lisowski L; Biro M; McCaughan GW; Bowen DG; Bertolino P, 2024, 'A hepatic network of dendritic cells mediates CD4 T cell help outside lymphoid organs', Nature Communications, 15, http://dx.doi.org/10.1038/s41467-024-45612-5

Mazalo JK; Tay SS; Kempe D; Biro M, 2024, 'Chemokine receptor distribution on the surface of repolarizing T cells', Biophysical Journal, 123, pp. 2328 - 2342, http://dx.doi.org/10.1016/j.bpj.2024.02.001

Golo M; Newman PLH; Kempe D; Biro M, 2024, 'Mechanoimmunology in the solid tumor microenvironment', Biochemical Society Transactions, 52, pp. 1489 - 1502, http://dx.doi.org/10.1042/BST20231427

Newman PLH; Yip Q; Osteil P; Anderson TA; Sun JQJ; Kempe D; Biro M; Shin JW; Tam PPL; Zreiqat H, 2023, 'Programming of Multicellular Patterning with Mechano-Chemically Microstructured Cell Niches', Advanced Science, 10, http://dx.doi.org/10.1002/advs.202204741

Govendir MA; Kempe D; Sianati S; Cremasco J; Mazalo JK; Colakoglu F; Golo M; Poole K; Biro M, 2022, 'T cell cytoskeletal forces shape synapse topography for targeted lysis via membrane curvature bias of perforin', Developmental Cell, 57, pp. 2237 - 2247.e8, http://dx.doi.org/10.1016/j.devcel.2022.08.012

Ecker M; Schregle R; Kapoor-Kaushik N; Rossatti P; Betzler VM; Kempe D; Biro M; Ariotti N; Redpath GMI; Rossy J, 2022, 'SNX9-induced membrane tubulation regulates CD28 cluster stability and signalling', eLife, 11, http://dx.doi.org/10.7554/eLife.67550

Cavanagh H; Kempe D; Mazalo JK; Biro M; Endres RG, 2022, 'T cell morphodynamics reveal periodic shape oscillations in three-dimensional migration', Journal of the Royal Society Interface, 19, http://dx.doi.org/10.1098/rsif.2022.0081

Geoghegan ND; Evelyn C; Whitehead LW; Pasternak M; McDonald P; Triglia T; Marapana DS; Kempe D; Thompson JK; Mlodzianoski MJ; Healer J; Biro M; Cowman AF; Rogers KL, 2021, '4D analysis of malaria parasite invasion offers insights into erythrocyte membrane remodeling and parasitophorous vacuole formation', Nature Communications, 12, http://dx.doi.org/10.1038/s41467-021-23626-7

Newman P; Yip Q; Osteil P; Anderson T; Sun J; Kempe D; Biro M; Shin J-W; Tam PPL; Zreiqat H, 2021, 'Material-mediated histogenesis using mechano-chemically microstructured cell niches', , http://dx.doi.org/10.1101/2021.02.10.430691

Niño JLG; Pageon SV; Tay SS; Colakoglu F; Kempe D; Hywood J; Mazalo JK; Cremasco J; Govendir MA; Dagley LF; Hsu K; Rizzetto S; Zieba J; Rice G; Prior V; O’neill G; Williams RJ; Nisbet DR; Kramer B; Webb AI; Luciani F; Read MN; Biro M, 2020, 'Cytotoxic T cells swarm by homotypic chemokine signalling', eLife, 9, pp. 1 - 71, http://dx.doi.org/10.7554/eLife.56554

Niño JLG; Tay SS; Tearle JLE; Xie J; Govendir MA; Kempe D; Mazalo J; Drew AP; Colakoglu F; Kummerfeld SK; Proud CG; Biro M, 2020, 'The lifeact-EGFP mouse is a translationally controlled fluorescent reporter of T cell activation', Journal of Cell Science, 133, http://dx.doi.org/10.1242/JCS.238014

Höfig H; Yukhnovets O; Remes C; Kempf N; Katranidis A; Kempe D; Fitter J, 2019, 'Brightness-gated two-color coincidence detection unravels two distinct mechanisms in bacterial protein translation initiation', Communications Biology, 2, http://dx.doi.org/10.1038/s42003-019-0709-7

Junker NO; Vaghefikia F; Albarghash A; Höfig H; Kempe D; Walter J; Otten J; Pohl M; Katranidis A; Wiegand S; Fitter J, 2019, 'Impact of Molecular Crowding on Translational Mobility and Conformational Properties of Biological Macromolecules', Journal of Physical Chemistry B, 123, pp. 4477 - 4486, http://dx.doi.org/10.1021/acs.jpcb.9b01239

Redpath GMI; Ecker M; Kapoor-Kaushik N; Vartoukian H; Carnell M; Kempe D; Biro M; Ariotti N; Rossy J; Kaushik N, 2019, 'Flotillins promote T cell receptor sorting through a fast Rab5–Rab11 endocytic recycling axis', Nature Communications, 10, pp. 4392, http://dx.doi.org/10.1038/s41467-019-12352-w

Pageon SV; Govendir MA; Kempe D; Biro M, 2018, 'Mechanoimmunology: Molecular-scale forces govern immune cell functions', Molecular Biology of the Cell, 29, pp. 1919 - 1926, http://dx.doi.org/10.1091/mbc.E18-02-0120

Kempe D; Cerminara M; Poblete S; Schöne A; Gabba M; Fitter J, 2017, 'Single-Molecule FRET Measurements in Additive-Enriched Aqueous Solutions', Analytical Chemistry, 89, pp. 694 - 702, http://dx.doi.org/10.1021/acs.analchem.6b03147

Albarghash A; Kempe D; Ole Junker N; Simone Hillebrecht B; Melchior Landmesser F; Fitter J, 2016, 'FCS on Proteins in Crowded Environments', Biophysical Journal, 110, pp. 50a - 50a, http://dx.doi.org/10.1016/j.bpj.2015.11.334

Kempf NM; Remes C; Kempe D; Katranidis A; Fitter J, 2016, 'In Vitro Optimization of Translational Activity with Modified Ribosomes', Biophysical Journal, 110, pp. 352a - 352a, http://dx.doi.org/10.1016/j.bpj.2015.11.1895

Schöne A; Kempe D; Cerminara M; Gabba M; Züchner T; Fitter J, 2016, 'Unfolding/Folding of a Multi-Domain Protein Untangled by Single-Molecule FRET', Biophysical Journal, 110, pp. 636a - 636a, http://dx.doi.org/10.1016/j.bpj.2015.11.3407

Kempe D; Schöne A; Fitter J; Gabba M, 2015, 'Accurate Fluorescence Quantum Yield Determination by Fluorescence Correlation Spectroscopy', Journal of Physical Chemistry B, 119, pp. 4668 - 4672, http://dx.doi.org/10.1021/acs.jpcb.5b02170

Gabba M; Poblete S; Rosenkranz T; Katranidis A; Kempe D; Züchner T; Winkler RG; Gompper G; Fitter J, 2014, 'Conformational state distributions and catalytically relevant dynamics of a hinge-bending enzyme studied by single-molecule fret and a coarse-grained simulation', Biophysical Journal, 107, pp. 1913 - 1923, http://dx.doi.org/10.1016/j.bpj.2014.08.016

Lamprou P; Kempe D; Katranidis A; Büldt G; Fitter J, 2014, 'Inside Cover: Nanosecond Dynamics of Calmodulin and Ribosome‐Bound Nascent Chains Studied by Time‐Resolved Fluorescence Anisotropy (ChemBioChem 7/2014)', ChemBioChem, 15, pp. 906 - 906, http://dx.doi.org/10.1002/cbic.201490021

Lamprou P; Kempe D; Katranidis A; Büldt G; Fitter J, 2014, 'Nanosecond dynamics of calmodulin and ribosome-bound nascent chains studied by time-resolved fluorescence anisotropy', ChemBioChem, 15, pp. 977 - 985, http://dx.doi.org/10.1002/cbic.201400014

Höfig H; Gabba M; Poblete S; Kempe D; Fitter J, 2014, 'Inter-dye distance distributions studied by a combination of single-molecule FRET-filtered lifetime measurements and a weighted accessible volume (wAV) algorithm', Molecules, 19, pp. 19269 - 19291, http://dx.doi.org/10.3390/molecules191219269

Gabba M; Poblete S; Kempe D; Schöne A; Züchner T; Gompper G; Fitter J, 2014, 'Interdomain Dynamics of Phosphoglycerate Kinase Studied by Single-Molecule FRET and a Mesoscale Hydrodynamics Simulation', Biophysical Journal, 106, pp. 253a - 253a, http://dx.doi.org/10.1016/j.bpj.2013.11.1488

Kempe D; Lamprou P; Katranidis A; Büldt G; Fitter J, 2014, 'Nanosecond Dynamics of Calmodulin and Ribosome-Bound Nascent Chains Studied by Time-Resolved Fluorescence Anisotropy', Biophysical Journal, 106, pp. 670a - 671a, http://dx.doi.org/10.1016/j.bpj.2013.11.3715

Preprints

Lau D; Tang Y; Kenche V; Copie T; Kempe D; Jary E; Graves NJ; Biro M; Masters CL; Dzamko N; Gambin Y; Sierecki E, 2024, Single molecule fingerprinting reveals different growth mechanisms in seed amplification assays for different polymorphs of αSynuclein fibrils, http://dx.doi.org/10.1101/2024.03.05.583619

Cavanagh H; Kempe D; Mazalo JK; Biro M; Endres RG, 2022, T cell morphodynamics reveal periodic shape oscillations in 3D migration, http://dx.doi.org/10.48550/arxiv.2204.03692

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