Danielle’s research motivation is to generate scientific evidence to inform clinical practice and health policy that leads to better quality of care and health outcomes, leveraging real-world data. Over the past 15 years, Danielle has developed extensive research methods in working with population-based routine data collections, such as Medicare claims for pharmaceutical dispensings and health professional attendances (PBS and MBS data), perinatal data collection, hospital admissions, emergency department presentations, medical records extracted from general practices, and registries (birth, death, cancer, and congenital anomalies).

Having high-level technical expertise in ‘big-data’, Danielle has been leading multi-national studies investigating the use and safety of prescription medicines for smoking cessation, mental health and substance use dependence in pregnant population. Her research in maternal smoking and smoking cessation pharmaco-therapies has been used in the “Tobacco in Australia: Facts and Issues” editions - national tobacco control resources for clinicians, public health and policy makers.

In addition, she’s led a study to evaluate patient accessing health services, quality of care, and health outcomes as part of the five-year national evaluation of Health Care Homes trial. The evaluation directly informs the reform of primary care as outlined in the Australia's Primary Health Care 10 Year Plan 2022-2032. Besides, Danielle has a key role in the development of the 'Join Us’ research participant register’ - the first national research resource to engage many Australian adults in health and medical research in timely manner. Since its launch in late 2021, the registry has provided support for more than 30 research studies in recruitment of study participants, improving research productivity and efficiency.

Danielle’s prior research included evaluations of patient compliance to Australian healthdirect telephone triage service, and development and implementation of hospital policies including inpatient assessments for drug and alcohol, fall prevention, clinical handover and error-reduction strategies.