By Dr Holly Holliday

Journal articles

Ross SE; Holliday H; Wang E; Zeraati M; Tsoli M; Ziegler DS; Dinger ME, 2026, 'RNA N6-methyladenosine (m6A) regulates cell cycle progression in diffuse midline glioma (DMG) and confers sensitivity to FTO inhibition', Cell Death and Disease, 17, http://dx.doi.org/10.1038/s41419-026-08647-8

Lawrence D; Upton D; Tax G; Holliday H; Ung C; Gopalakrishnan A; Liu J; Emmy M; Dolman M; Roebuck J; Mao J; Sivanathan A; Cai D; Rayner B; Tsoli M; Ziegler DS, 2026, 'ID #429 Therapeutic development of the clinically active compound ACT001 with Mcl-1 inhibitors for the treatment of paediatric diffuse midline glioma', Neuro-Oncology Pediatrics, 2, pp. wuag026.148, http://dx.doi.org/10.1093/neuped/wuag026.148

Sanguino YC; Fox S; Rodriguez de la Fuente L; Cassim A; Li S; Kearney P; Jackson E; Duchatel R; Holliday H; Tsoli M; Dun M; Mora FV, 2026, 'ID #448 Epigenomic erosion and enhancer dependence in H3.3K27M diffuse midline glioma', Neuro-Oncology Pediatrics, 2, pp. wuag026.154, http://dx.doi.org/10.1093/neuped/wuag026.154

Lee G; Chen Y; Gopalakrishnan A; Liu J; Lawrence D; Holliday H; Tsoli M; Ip KCK; Ziegler D, 2026, 'ID #598 Unravelling the Role of Neural Progenitor Cells in the Development of Paediatric High-Grade Glioma', Neuro-Oncology Pediatrics, 2, pp. wuag026.228, http://dx.doi.org/10.1093/neuped/wuag026.228

Sanguino YC; Fox S; Cassim A; Rodriguez de la Fuente L; Li S; Jackson E; Duchatel R; Holliday H; Gopalakrishnan A; Tsoli M; Ziegler D; Ortega DG; Dun M; Mora FV, 2026, 'ID #674 Unmasking Epigenomic Vulnerabilities in Diffuse Midline Glioma to Guide Epigenetic Therapy', Neuro-Oncology Pediatrics, 2, http://dx.doi.org/10.1093/neuped/wuag026.273

Sun C; Holliday H; Luo M; Wang E; Firestein R, 2026, 'ID #828 CCMA-EPIC an epigenetic driven framework for biomarker discovery in paediatric brain tumours', Neuro-Oncology Pediatrics, 2, http://dx.doi.org/10.1093/neuped/wuag026.348

Apostolov E; Roden DL; Holliday H; Cazet A; Harvey K; Zhang H; Wu SZ; van der Leij S; Jieun Kim H; Selth LA; Bartonicek N; Al-Eryani G; Reeves JL; He M; Lundeberg J; Potter AJ; Kench JG; Stricker PD; Joshua AM; Horvath LG; Swarbrick A, 2026, 'Single-Cell and Spatial Transcriptomic Profiling Reveals Epithelial Functional States and Fibroblast Phenotypes in Hormone Therapy-Naïve Localized Prostate Cancer', Cancer Research, 86, pp. 1836 - 1853, http://dx.doi.org/10.1158/0008-5472.CAN-25-1202

Holliday H; Poulos RC, 2026, 'On the origins of childhood cancer', Cancer and Metastasis Reviews, 45, http://dx.doi.org/10.1007/s10555-026-10323-4

Holliday H; Khan A; Ehteda A; Nguyen H; Ross SE; Jayatilleke N; Gopalakrishnan A; Wang E; Sanguino YC; Kavanagh D; Guo X; Liu J; Lawrence D; Sun CX; Lehmann R; Ip CK; Lee A; Rangel-Sanchez L; Li W; Salomon R; Firestein R; Weatheritt RJ; Valdes-Mora F; Dinger ME; Phoenix TN; Mayoh C; Rayner BS; Tsoli M; Ziegler DS, 2026, 'Combined inhibition of FACT and BET disrupts transcription to suppress tumor growth in mouse models of diffuse midline glioma', Science Translational Medicine, 18, http://dx.doi.org/10.1126/scitranslmed.adr1557

Mateos MK; Ajuyah P; Fuentes-Bolanos N; El-Kamand S; Barahona P; Altekoester AK; Mayoh C; Holliday H; Liu J; Cui L; Pfaff E; Mackay A; Resnick AC; Pinese M; Lau LMS; Khuong-Quang DA; Dias K; Goudie C; Salkeld A; Rokita JL; Jones DTW; Juretic N; Hayden E; Pfister SM; Kramm CM; Blattner-Johnson M; Jabado N; Tsoli M; Vittorio O; Mueller S; Guo Y; Tucker K; Waszak SM; Perreault S; Jones C; Wong-Erasmus M; Cowley MJ; Ziegler DS, 2025, 'Germline analysis of an international cohort of pediatric diffuse midline glioma patients', Neuro Oncology, 27, pp. 1849 - 1863, http://dx.doi.org/10.1093/neuonc/noaf061

Upton DH; Liu J; George SM; Valvi S; Ung C; Rayner BS; Gopalakrishnan A; Pandher R; Khan A; Venkat P; Mayoh C; Holliday H; Yeung N; Nguyen H; Franshaw L; Ehteda A; Shen H; Farruggia G; Orienti I; Reynolds CP; Tsoli M; Ziegler DS, 2025, 'High-throughput in vitro drug screening and in vivo studies identify fenretinide as a brain-penetrant DMG therapeutic', Neuro Oncology, 27, pp. 1813 - 1828, http://dx.doi.org/10.1093/neuonc/noaf035

Pereira BA; Ritchie S; Chambers CR; Gordon KA; Magenau A; Murphy KJ; Nobis M; Tyma VM; Liew YF; Lucas MC; Naeini MM; Barkauskas DS; Chacon-Fajardo D; Howell AE; Parker AL; Warren SC; Reed DA; Lee V; Metcalf XL; Lee YK; O'Regan LP; Zhu J; Trpceski M; Fontaine ARM; Stoehr J; Rouet R; Lin X; Chitty JL; Porazinski S; Wu SZ; Filipe EC; Cadell AL; Holliday H; Yang J; Papanicolaou M; Lyons RJ; Zaratzian A; Tayao M; Da Silva A; Vennin C; Yin J; Dew AB; McMillan PJ; Goldstein LD; Deveson IW; Croucher DR; Samuel MS; Sim HW; Batten M; Chantrill L; Grimmond SM; Gill AJ; Samra J; Jeffry Evans TR; Sasaki T; Phan TG; Swarbrick A; Sansom OJ; Morton JP; Pajic M; Parker BL; Herrmann D; Cox TR; Timpson P, 2024, 'Temporally resolved proteomics identifies nidogen-2 as a cotarget in pancreatic cancer that modulates fibrosis and therapy response', Science Advances, 10, http://dx.doi.org/10.1126/sciadv.adl1197

Holliday H; Yang J; Dodson E; Nikolic I; Kamili A; Wheatley M; Deng N; Alexandrou S; Davis TP; Kavallaris M; Caldon CE; McCarroll J; De Preter K; Mestdagh P; Marshall GM; Simpson KJ; Fletcher J; Swarbrick A, 2024, 'Erratum: miR-99b-5p, miR-380-3p, and miR-485-3p are novel chemosensitizing miRNAs in high-risk neuroblastoma (Molecular Therapy (2022) 30(3) (1119–1134), (S1525001622000041), (10.1016/j.ymthe.2022.01.004))', Molecular Therapy, 32, pp. 2031 - 2033, http://dx.doi.org/10.1016/j.ymthe.2024.05.008

Ross SE; Holliday H; Tsoli M; Ziegler DS; Dinger ME, 2024, 'Abstract B015: RNA N6-methyladenosine (m6A) as a therapeutic target in Diffuse Midline Glioma (DMG)', Cancer Research, 84, pp. b015 - b015, http://dx.doi.org/10.1158/1538-7445.brain23-b015

Glover HJ; Holliday H; Shparberg RA; Winkler D; Day M; Morris MB, 2023, 'Signalling pathway crosstalk stimulated by L-proline drives mouse embryonic stem cells to primitive-ectoderm-like cells', Development Cambridge, 150, http://dx.doi.org/10.1242/dev.201704

Thai LM; O'Reilly L; Reibe-Pal S; Sue N; Holliday H; Small L; Schmitz-Peiffer C; Dhenni R; Wang-Wei Tsai V; Norris N; Yau B; Zhang X; Lee K; Yan C; Shi YC; Kebede MA; Brink R; Cooney GJ; Irvine KM; Breit SN; Phan TG; Swarbrick A; Biden TJ, 2023, 'β-cell function is regulated by metabolic and epigenetic programming of islet-associated macrophages, involving Axl, Mertk, and TGFβ receptor signaling', Iscience, 26, http://dx.doi.org/10.1016/j.isci.2023.106477

Holliday H; Yang J; Dodson E; Nikolic I; Kamili A; Wheatley M; Deng N; Alexandrou S; Davis TP; Kavallaris M; Caldon CE; McCarroll J; De Preter K; Mestdagh P; Marshall GM; Simpson KJ; Fletcher J; Swarbrick A, 2022, 'miR-99b-5p, miR-380-3p, and miR-485-3p are novel chemosensitizing miRNAs in high-risk neuroblastoma', Molecular Therapy, 30, pp. 1119 - 1134, http://dx.doi.org/10.1016/j.ymthe.2022.01.004

Hayden E; Holliday H; Lehmann R; Khan A; Tsoli M; Rayner BS; Ziegler DS, 2021, 'Therapeutic targets in diffuse midline gliomas—an emerging landscape', Cancers, 13, http://dx.doi.org/10.3390/cancers13246251

Holliday H; Khoury A; Swarbrick A, 2021, 'Chromatin immunoprecipitation of transcription factors and histone modifications in Comma-Dβ mammary epithelial cells', STAR Protocols, 2, http://dx.doi.org/10.1016/j.xpro.2021.100514

Holliday H; Roden D; Junankar S; Wu SZ; Baker LA; Krisp C; Chan CL; McFarland A; Skhinas JN; Cox TR; Pal B; Huntington ND; Ormandy CJ; Carroll JS; Visvader J; Molloy MP; Swarbrick A, 2021, 'Inhibitor of Differentiation 4 (ID4) represses mammary myoepithelial differentiation via inhibition of HEB', Iscience, 24, http://dx.doi.org/10.1016/j.isci.2021.102072

McEvoy CR; Holliday H; Thio N; Mitchell C; Choong DY; Yellapu B; Leong HS; Xu H; Lade S; Browning J; Takano EA; Byrne DJ; Gill AJ; Duong CP; Li J; Fellowes AP; Fox SB; Swarbrick A; Prall OWJ, 2021, 'A MXI1-NUTM1 fusion protein with MYC-like activity suggests a novel oncogenic mechanism in a subset of NUTM1-rearranged tumors', Laboratory Investigation, 101, pp. 26 - 37, http://dx.doi.org/10.1038/s41374-020-00484-3

McEvoy CR; Holliday H; Thio N; Mitchell C; Choong DY; Yellapu B; Leong HS; Xu H; Lade S; Browning J; Takano EA; Byrne DJ; Gill AJ; Duong CP; Li J; Fellowes AP; Fox SB; Swarbrick A; Prall OWJ, 2021, 'A MXI1-NUTM1 fusion protein with MYC-like activity suggests a novel oncogenic mechanism in a subset of NUTM1-rearranged tumors.', Lab Invest, 101, pp. 26 - 37, http://dx.doi.org/10.1038/s41374-020-00484-3

Wu SZ; Roden DL; Wang C; Holliday H; Harvey K; Cazet AS; Murphy KJ; Pereira B; Al-Eryani G; Bartonicek N; Hou R; Torpy JR; Junankar S; Chan CL; Lam CE; Hui MN; Gluch L; Beith J; Parker A; Robbins E; Segara D; Mak C; Cooper C; Warrier S; Forrest A; Powell J; O'Toole S; Cox TR; Timpson P; Lim E; Liu XS; Swarbrick A, 2020, 'Stromal cell diversity associated with immune evasion in human triple-negative breast cancer', EMBO Journal, 39, pp. embj2019104063, http://dx.doi.org/10.15252/embj.2019104063

Thankamony AP; Murali R; Karthikeyan N; Varghese BA; Teo WS; McFarland A; Roden DL; Holliday H; Konrad CV; Cazet A; Dodson E; Yang J; Baker LA; George JT; Levine H; Jolly MK; Swarbrick A; Nair R, 2020, 'Targeting the id1-kif11 axis in triple-negative breast cancer using combination therapy', Biomolecules, 10, pp. 1 - 15, http://dx.doi.org/10.3390/biom10091295

Teo WS; Holliday H; Karthikeyan N; Cazet AS; Roden DL; Harvey K; Konrad CV; Murali R; Varghese BA; Thankamony AP; Chan CL; McFarland A; Junankar S; Ye S; Yang J; Nikolic I; Shah JS; Baker LA; Millar EKA; Naylor MJ; Ormandy CJ; Lakhani SR; Kaplan W; Mellick AS; O'Toole SA; Swarbrick A; Nair R, 2020, 'Id Proteins Promote a Cancer Stem Cell Phenotype in Mouse Models of Triple Negative Breast Cancer via Negative Regulation of Robo1', Frontiers in Cell and Developmental Biology, 8, http://dx.doi.org/10.3389/fcell.2020.00552

Baker LA; Holliday H; Roden D; Krisp C; Wu SZ; Junankar S; Serandour AA; Mohammed H; Nair R; Sankaranarayanan G; Law AMK; McFarland A; Simpson PT; Lakhani S; Dodson E; Selinger C; Anderson L; Samimi G; Hacker NF; Lim E; Ormandy CJ; Naylor MJ; Simpson K; Nikolic I; O'Toole S; O'Toole S; O'Toole S; O'Toole S; Kaplan W; Cowley MJ; Carroll JS; Molloy M; Swarbrick A, 2020, 'Proteogenomic analysis of Inhibitor of Differentiation 4 (ID4) in basal-like breast cancer', Breast Cancer Research, 22, http://dx.doi.org/10.1186/s13058-020-01306-6

Holliday H; Baker LA; Junankar SR; Clark SJ; Swarbrick A, 2018, 'Epigenomics of mammary gland development', Breast Cancer Research, 20, http://dx.doi.org/10.1186/s13058-018-1031-x

Baker LA; Holliday H; Swarbrick A, 2016, 'ID4 controls luminal lineage commitment in normal mammary epithelium and inhibits BRCA1 function in basal-like breast cancer', Endocrine Related Cancer, 23, pp. R381 - R392, http://dx.doi.org/10.1530/ERC-16-0196

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