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Researcher

Dr Jane Ellen Carland

Keywords

Fields of Research (FoR)

Clinical pharmacology and therapeutics, Basic pharmacology, Public health, Health services and systems, Rural and remote health services

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Biography

Jane Carland is a Senior Hospital Scientist in the Department of Clinical Pharmacology and Toxicology, St Vincent's Hospital, Sydney. She is also a conjoint Associate Professor, St Vincent’s Clinical School, UNSW Sydney and Chair, St Vincent's Hospital HREC.

Jane has a strong background in pharmacology research, extending from molecular pharmacology of neurotransmission to quality use of medicines. Jane gained her PhD from the University of...view more

Jane Carland is a Senior Hospital Scientist in the Department of Clinical Pharmacology and Toxicology, St Vincent's Hospital, Sydney. She is also a conjoint Associate Professor, St Vincent’s Clinical School, UNSW Sydney and Chair, St Vincent's Hospital HREC.

Jane has a strong background in pharmacology research, extending from molecular pharmacology of neurotransmission to quality use of medicines. Jane gained her PhD from the University of Sydney under the supervision of Professors Mary Collins (Chebib) and Graham Johnston, her work describing the role of key residues on the function of GABAC receptors. Jane subsequently extended her structure-function studies of neurotransmitter ligand-gated ion channel receptors and transporters, taking up a post-doctoral position at the University of Dundee, UK, before returning to Australia as a UNSW Vice-Chancellors Research Fellow and then working with the Transporter Biology Group in the Discipline of Pharmacology, University of Sydney. She has since moved to work within the Department of Clinical Pharmacology and Toxicology, St Vincent's Hospital, Sydney.

Jane's research interests include structure-function studies of neurotransmitter receptors and transporters, optimising immunosuppressant therapy in heart and lung transplant, extending use of metformin to complex patient populations (including heart failure and renal failure), influences on prescribing decision-making, evaluating therapeutic drug monitoring processes and exploring informed consent – an ethical tenant that is central to the researcher-participant relationship in clinical research. 

Jane is a passionate advocate for research integration within the clinical setting, contributing to research development activities across the St Vincent's precinct, and providing academic supervision and mentorship to Honours, Year 4 Medicine and PhD students. Jane teaches into UNSW pharmacology courses, represents the St Vincent’s Clinical School on the UNSW Year 4 Medicine Committee, is Chair of the St Vincent’s Hospital Human Research Ethics Committee and co-Director of the TDM Service for vancomycin. Her love of research is reflected in her interest in conveying research outcomes to the community, from pre-school science classes and School Outreach programs to volunteering as a research co-ordinator for the Pink Elephants Support Network.


My Grants

2023.     Digital Health CRC ($410,000) "Evaluation of the Western Australia Country Health Service's Antimicrobial Stewardship decision support tool" 

2022     NSW Investing in Women Grant ($100,000) "Pink Elephants Network, Peer Support Program Evaluation"

2021    St Vincent’s Curran Foundation Endowment Award ($35,000) "What data do we need to improve the use of antimicrobials in patients receiving dialysis for kidney failure?" (Marriott DJ, Stojanova J, Carland JE, Roberts D, Brett J, Day RO, Buscher H)

2018    St Vincent’s Curran Foundation Endowment Award ($35,000) “Metabolomics of Metformin in Heart Failure” (Carland JE, Stocker SL, Chowdhury G)

2018    St Vincent’s Curran Foundation Endowment Award ($30,000) “Optimising Tacrolimus Therapy in Lung Transplant Patients” (Carland JE, Stocker SL)

2017/2018    The Friends of the Mater Foundation Grant Application. ($10,000) “Pharmacokinetic factors associated with scalp cooling efficacy for docetaxel-containing regimens in cancer patients” (Boyle F, Dear R, Andrews K, Carland J, Stocker S)

2017    UNSW Research Infrastructure Scheme ($78,431) “Installation of a Shimadzu Nexera X2 UHPLC into the Department of Clinical Pharmacology and Toxicology” (Day RO, Carland JE, Stocker SL, Norris RLG, Greenfield JR)

2017    St Vincent’s Clinic Foundation Annual Research Grant ($30,000) “The safety and Pharmacokinetics of Metformin in Heart Failure” (Day R, Macdonald P, Greenfield J, Graham G, Carland J, Stocker S)

2015-2017     National Health and Medical Research Council (NHMRC) Project Grant “Novel Drugs for the Treatment of Chronic Pain” (App 1082570; Vandenberg R, O'Mara M, Imlach W, Rawling T, Carland J, Ryan R)

2013    Sydney Medical School Early Career Researcher Grant 
2008    Ian Potter Foundation Travel Grant
2008    UNSW Faculty of Medicine Early Career Researcher Grant
2008    UNSW Vice Chancellor’s Postdoctoral Research Fellow
2006    UK Brain Travel Grant
2001    Australian Postgraduate Award, University of Sydney
2000    Faculty of Medicine Honours Scholarship, University of Sydney
1999    National Institute of Schizophrenia and Allied Disorders (NISAD) Summer Student Scholarship
1997    University Entry Scholarship, University of Sydney


My Qualifications

BMedSci (HonsI), PhD


My Awards

2021    UNSW Students' Choice Teaching Award Nominee

2019    UNSW Arc Research Supervisor Award

2014    BPS/ASCEPT Outstanding Young Investigator Prize

2014    ASCEPT Denis Wade Johnson and Johnson New Investigator Award

2012    Rebecca L. Cooper Medical Research Foundation Medal

2012    Presentation Award, Membrane Transporters Workshop

2010    Paper of the Month (June), School of Medical Sciences, UNSW

2009    Awarded UNSW School of Medical Sciences New Researcher of the Year 
2009    Awarded UNSW Faculty of Medicine, Dean’s Rising Star Award
2009    Paper of the Month (January), School of Medical Sciences, UNSW
2008    Awarded a place at the Australian Course in Advanced Neuroscience
2001    Australian Postgraduate Award
2000    University Medal, University of Sydney
2000    Wheelan Prize, ASCEPT Honours Student Poster Presentation
2000    Highly commended, Tocris Neuropharmacology Poster Prize
1999    National Institute of Schizophrenia and Allied Disorders (NISAD) Summer Student Scholarship, 
1999    Roland H Thorp Prize in Pharmacology
1997-1999    Dean’s List, University of Sydney
 


My Research Activities

I have a strong background in pharmacology research, extending from molecular pharmacology of neurotransmission to understanding and improving the use of medicines in practice. My work currently focusses on immunosuppressant therapy in lung transplant, extending use of metformin to complex patient populations (including heart failure and renal failure), as well as exploring informed consent – an ethical tenant that is central to the researcher-participant relationship in clinical research. My love of research is reflected in my interest in conveying research outcomes to the community, from pre-school science classes to School Outreach programs.


My Research Supervision


Supervision keywords


Areas of supervision

Students: Honours, ILP, MSc, PhD

Quality use of medicines - Immunosuppressant therapy in heart and lung transplant, extending use of metformin to complex patient populations (including heart failure and renal failure), exploring informed consent and the role of human research ethics committees, evaluating therapeutic drug monitoring processes, understanding influences on prescribing decision-making, exploring the implementation and use of digital tools to improve prescribing


Currently supervising

Postgraduate Supervision

2023              Year 4 Medical Student Supervisor, Faculty of Medicine, UNSW

2023              Year 4 Medical Student Supervisor, Faculty of Medicine, UNSW

2023              Year 4 Medical Student Supervisor, Faculty of Medicine, UNSW

2022              Honours Student Co-Supervisor, University of Sydney, NSW

2022               Year 4 Medical Student Supervisor, Faculty of Medicine, UNSW

2022               Honours Student Supervisor, School of Medical Science, UNSW     

2022               Honours Student Co-supervisor, School of Medical Science, UNSW

2021               Year 4 Medical Student Supervisor, Faculty of Medicine, UNSW

2021               Honours Student Supervisor, School of Medical Science, UNSW     

2021               Honours Student Supervisor, School of Medical Science, UNSW

2020               Honours Student Supervisor, School of Medical Science, UNSW

2019               ILP Student Supervisor, Faculty of Medicine, UNSW

2019               BSc(Med) Student Supervisor, Faculty of Medicine, UNSW

2019                Honours Student Supervisor, School of Medical Science, UNSW

2018-2022      PhD Student Co-supervisor, St Vincent's Clinical School, UNSW

2017-               PhD Student Secondary Supervisor, School of Medical Science, UNSW

2016-2017       Honours Student Supervisor, School of Medical Sciences, UNSW

2016-2017       BMed(Sc) and ILP Supervisory, St Vincent's Clinical School, UNSW

2016                Honours Student Co-supervisor, Discipline of Pharmacology, University of Sydney

2014-2018       PhD Student Associate Supervisor, Discipline of Pharmacology, University of Sydney

2013                Honours Student Co-supervisor, Discipline of Pharmacology, University of Sydney

2010-2012       PhD Student Associate Supervisor, Faculty of Pharmacy, University of Sydney

2009                Honours Student Co-supervisor, Department of Physiology UNSW


My Engagement

2022 - ongoing   Chair, St Vincent's Hospital Human Research Ethics Committee

2020 -2021         Committee Member, St Vincent's Hospital Human Research Ethics Committee

2019-ongoing     Research Coordinator (Volunteer) Pink Elephants Support Network

2019-ongoing    UNSW Year 4 Medicine Committee Member

2018-ongoing    PhD Review Panel Member, St Vincent's Clinical School, UNSW

2018-2019         Schools Outreach Program Co-convenor, St Vincent's Campus Research Week

2017-ongoing    Fast Forward Sessions Co-convenor , St Vincent's Campus Research Week

2017-ongoing    St Vincent's Campus Research Week Organising Committee Member

2015-2016        Denis Wade Johnson & Johnson New Investigator Award Committee Member, ASCEPT

2013-2019        Visiting Scientist, John Brotchie Preschool, Botany, NSW

 


My Teaching

Course Convening

2021 - PHAR3111 Clinical Pharmacology for HESC Course Co-Convenor

2020-2021 - PHAR3202 Neuropharmacology Course Co-Convenor

2020 - PHAR3251 Clinical and Experimental Pharmacology Course Co-Convenor

 

Lectures

2021 - PHAR3111 Clinical Pharmacology for HESC, UNSW

2021 - PHAR3102 Molecular Pharmacology, UNSW

2020 - PHAR3306 Pharmacology (Optometry), UNSW

2008-2013, 2018-2023 - PHAR3202 Neuropharmacology, UNSW

2015 - Research Inquiry 5020, Brain and Mind Research Institute, University of Sydney

2013-2016 - Stage 2, Medical and Dental Program, University of Sydney

2008 - Membrane and Cellular Physiology, Department of Physiology, UNSW

2003 - Pharmacology, Faculty of Nursing, University of Sydney

 

Tutorials

2021 - PHAR3111 Clinical Pharmacology for HESC, UNSW

2020 - PHAR3306 Pharmacology (Optometry), UNSW

2020 - PHAR3202 Neuropharmacology, UNSW

2018 - Year 4 Medicine, ILP Peer Support Session 1: Human and Animal Ethics, St Vincent's Clinical School, UNSW

2011 - Neuropharmacology, Discipline of Pharmacology, University of Sydney

2008 - Membrane and Cellular Physiology, Department of Physiology, UNSW

2006-2007 - Drugs and Drug Targets, Faculty of Life Sciences, University of Dundee, UK

2001-2001 - Medicinal Chemistry, Faculty of Pharmacy, University of Sydney

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Location

Department of Clinical Pharmacology & Toxicology,
Therapeutics Centre, St Vincent’s Hospital Sydney
Conjoint Senior Lecturer, St Vincent’s Clinical School, UNSW Sydney

Level 2 Xavier Building, 390 Victoria Street, Darlinghurst, Sydney 2010


Map reference (Google map)

Contact

02 8382 2617
02 8382 2724