Researcher

Keywords

Fields of Research (FoR)

Genomics and transcriptomics, Gastroenterology and hepatology, Cellular immunology, Microbiology

Biography

 

Dr Kylie James is head of the Gut Immunogenomics Laboratory. She completed a PhD in T cell immunity to malaria in 2017, with Dr Ashraful Haque at QIMR Berghofer. She then undertook postdoctoral training at the Wellcome Sanger Institute in the laboratory of Dr Sarah Teichmann, and a junior research fellowship at Christ’s College, University of Cambridge. Here, she spearheaded the cell atlas of the human intestinal tract across anatomical...view more

 

Dr Kylie James is head of the Gut Immunogenomics Laboratory. She completed a PhD in T cell immunity to malaria in 2017, with Dr Ashraful Haque at QIMR Berghofer. She then undertook postdoctoral training at the Wellcome Sanger Institute in the laboratory of Dr Sarah Teichmann, and a junior research fellowship at Christ’s College, University of Cambridge. Here, she spearheaded the cell atlas of the human intestinal tract across anatomical space and developmental time and showed the influence of the neighbouring microbiota in shaping the intestinal immune cell landscape. In 2021, Kylie returned to Australia to start her team as Spinak Fellow and NHMRC Investigator Fellow.

 

The Gut Immunogenomics Laboratory uses single-cell and spatially-resolved gene expression technologies to investigate cellular and microbial contributions to intestinal disease.


My Grants

NHMRC Investigator Grant (2021-2026)

Spinak Fellowship (2021-2024)

Ramaciotti Health Investment (2021-2024)

Perpetual IMPACT (2021)

Christ’s College Junior Research Fellowship (2018-2020)


My Qualifications

PhD (Immunology), University of Queensland, 2016
BSc (Hons), University of Queensland, 2011


My Research Supervision


Areas of supervision

Intestinal cell responses during inflammatory bowel disease

Host-microbiome interactions

Computational biology

Single-cell approaches to cellular biology


Currently supervising

PhD and intern students

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Location

The Kinghorn Cancer Centre, The Garvan Institute of Medical Research, 370 Victoria St, Darlinghurst NSW 2010

Map reference (Google map)

Research Activities

 

Potential PhD topics:

 1. What ocean do Lagrangian observing platforms (e.g., Argo and drifting buoys) observe ?

In the mid- and high-latitudes the ocean circulation is composed largely of eddies and fronts. In isolation an ocean eddy is relatively stable being in quasi-geostrophic balance and retaining a closed material surface around its core water mass. It is only through the disruption or destruction of this balance through eddy- interactions that an exchange in mass with its environment takes place.…