By Dr Laurence Don Wai Luu

Journal articles

Xiao K; Cao Y; Han Z; Zhang Y; Luu LDW; Chen L; Yan P; Chen W; Wang J; Liang Y; Shi X; Wang X; Wang F; Hu Y; Wen Z; Chen Y; Yang Y; Yu H; Xie L; Wang Y, 2025, 'A pan-immune panorama of bacterial pneumonia revealed by a large-scale single-cell transcriptome atlas', Signal Transduction and Targeted Therapy, 10, http://dx.doi.org/10.1038/s41392-024-02093-8

Yang X; Wang C; Xue Y; Zhang Y; Zheng M; Sun Q; Long S; Wang D; Yan J; Liao X; Zhang T; Cao L; Chen Y; Ju W; Zhang J; Gao M; Zhao Y; Luu LDW; Pan J; Wang Y; Wang G, 2025, 'Clinical outcomes of patients with coronavirus disease 2019 and active tuberculosis co-infection in Beijing China: A retrospective single-center descriptive study', Infectious Medicine, 4, http://dx.doi.org/10.1016/j.imj.2025.100169

Luu LDW; Rafique R; Payne M; Octavia S; Robson J; Sintchenko V; Lan R, 2024, 'Deciphering Bordetella pertussis epidemiology through culture-independent multiplex amplicon and metagenomic sequencing', Journal of Clinical Microbiology, 62, http://dx.doi.org/10.1128/jcm.01178-24

Luu LDW; Pandey A; Paramsothy S; Ngo C; Castaño-Rodríguez N; Liu C; Kamm MA; Borody TJ; Man SM; Kaakoush NO, 2024, 'Profiling the colonic mucosal response to fecal microbiota transplantation identifies a role for GBP5 in colitis in humans and mice', Nature Communications, 15, http://dx.doi.org/10.1038/s41467-024-46983-5

Majzoub ME; Luu LDW; Haifer C; Paramsothy S; Borody TJ; Leong RW; Thomas T; Kaakoush NO, 2024, 'Refining microbial community metabolic models derived from metagenomics using reference-based taxonomic profiling', mSystems, 9, http://dx.doi.org/10.1128/msystems.00746-24

Wang Y; Yang S; Han B; Du X; Sun H; Du Y; Liu Y; Lu P; Di J; Luu LDW; Lv X; Hu S; Wang L; Jiang R, 2024, 'Single-cell landscape revealed immune characteristics associated with disease phases in brucellosis patients', iMeta, 3, http://dx.doi.org/10.1002/imt2.226

Strange N; Luu L; Ong V; Wee BA; Phillips MJA; McCaughey L; Steele JR; Barlow CK; Cranfield CG; Myers G; Mazraani R; Rock C; Timms P; Huston WM, 2024, 'HtrA, fatty acids, and membrane protein interplay in Chlamydia trachomatis to impact stress response and trigger early cellular exit', Journal of Bacteriology, 206, http://dx.doi.org/10.1128/jb.00371-23

Wang Y; Huang X; Li F; Jia X; Jia N; Fu J; Liu S; Zhang J; Ge H; Huang S; Hui Y; Sun C; Xiao F; Cui X; Luu LDW; Qu D; Li J; Tai J, 2023, 'Serum-integrated omics reveal the host response landscape for severe pediatric community-acquired pneumonia', Critical Care, 27, http://dx.doi.org/10.1186/s13054-023-04378-w

Wang Y; Luu LDW; Liu S; Zhu X; Huang S; Li F; Huang X; Guo L; Zhang J; Ge H; Sun Y; Hui Y; Qu Y; Wang H; Wang X; Na W; Zhou J; Qu D; Tai J, 2023, 'Single-cell transcriptomic analysis reveals a systemic immune dysregulation in COVID-19-associated pediatric encephalopathy', Signal Transduction and Targeted Therapy, 8, http://dx.doi.org/10.1038/s41392-023-01641-y

Wang Y; Sun Q; Zhang Y; Li X; Liang Q; Guo R; Zhang L; Han X; Wang J; Shao L; Xue Y; Yang Y; Li H; Nie L; Shi W; Liu Q; Zhang J; Duan H; Huang H; Luu LDW; Tai J; Yang X; Wang G, 2023, 'Systemic immune dysregulation in severe tuberculosis patients revealed by a single-cell transcriptome atlas', Journal of Infection, 86, pp. 421 - 438, http://dx.doi.org/10.1016/j.jinf.2023.03.020

Huang X; Li F; Wang Y; Jia X; Jia N; Xiao F; Sun C; Fu J; Chen M; Cui X; Qu D; Wai Luu LD; Tai J; Li J, 2023, 'Multi-omics analysis reveals underlying host responses in pediatric respiratory syncytial virus pneumonia', iScience, 26, http://dx.doi.org/10.1016/j.isci.2023.106329

Jury B; Fleming C; Huston WM; Luu LDW, 2023, 'Corrigendum: Molecular pathogenesis of Chlamydia trachomatis (Frontiers in Cellular and Infection Microbiology, (2023), 13, (1281823), 10.3389/fcimb.2023.1281823)', Frontiers in Cellular and Infection Microbiology, 13, http://dx.doi.org/10.3389/fcimb.2023.1358553

Luu LDW; Kasimov V; Phillips S; Myers GSA; Jelocnik M, 2023, 'Genome organization and genomics in Chlamydia: whole genome sequencing increases understanding of chlamydial virulence, evolution, and phylogeny', Frontiers in Cellular and Infection Microbiology, 13, http://dx.doi.org/10.3389/fcimb.2023.1178736

Wang Y; Wang X; Jia X; Li J; Fu J; Huang X; Cui X; Wang B; Luo W; Lin C; Li Z; Luu LDW; Li S; Zhu X; Tai J, 2023, 'Influenza vaccination features revealed by a single-cell transcriptome atlas', Journal of Medical Virology, 95, http://dx.doi.org/10.1002/jmv.28174

Suyama H; Luu LDW; Zhong L; Raftery MJ; Lan R, 2023, 'Integrating proteomic data with metabolic modeling provides insight into key pathways of Bordetella pertussis biofilms', Frontiers in Microbiology, 14, http://dx.doi.org/10.3389/fmicb.2023.1169870

Haifer C; Luu LDW; Paramsothy S; Borody TJ; Leong RW; Kaakoush NO, 2023, 'Microbial determinants of effective donors in faecal microbiota transplantation for UC', Gut, 72, pp. 90 - 100, http://dx.doi.org/10.1136/gutjnl-2022-327742

Jury B; Fleming C; Huston WM; Luu LDW, 2023, 'Molecular pathogenesis of Chlamydia trachomatis', Frontiers in Cellular and Infection Microbiology, 13, http://dx.doi.org/10.3389/fcimb.2023.1281823

Yang X; Yan J; Xue Y; Sun Q; Zhang Y; Guo R; Wang C; Li X; Liang Q; Wu H; Wang C; Liao X; Long S; Zheng M; Wei R; Zhang H; Liu Y; Che N; Luu LDW; Pan J; Wang G; Wang Y, 2023, 'Single-cell profiling reveals distinct immune response landscapes in tuberculous pleural effusion and non-TPE', Frontiers in Immunology, 14, http://dx.doi.org/10.3389/fimmu.2023.1191357

Wang Y; Wang X; Luu LDW; Li J; Cui X; Yao H; Chen S; Fu J; Wang L; Wang C; Yuan R; Cai Q; Huang X; Huang J; Li Z; Li S; Zhu X; Tai J, 2022, 'Single-cell transcriptomic atlas reveals distinct immunological responses between COVID-19 vaccine and natural SARS-CoV-2 infection', Journal of Medical Virology, 94, pp. 5304 - 5324, http://dx.doi.org/10.1002/jmv.28012

Wang Y; Wang X; Luu LDW; Chen S; Jin F; Wang S; Huang X; Wang L; Zhou X; Chen X; Cui X; Li J; Tai J; Zhu X, 2022, 'Proteomic and Metabolomic Signatures Associated With the Immune Response in Healthy Individuals Immunized With an Inactivated SARS-CoV-2 Vaccine', Frontiers in Immunology, 13, http://dx.doi.org/10.3389/fimmu.2022.848961

Huang X; Luu LDW; Jia N; Zhu J; Fu J; Xiao F; Liu C; Li S; Shu G; Hou J; Kang M; Zhang D; Xu Y; Wang Y; Cui X; Lai J; Li J; Tai J, 2022, 'Multi-Platform Omics Analysis Reveals Molecular Signatures for Pathogenesis and Activity of Systemic Lupus Erythematosus', Frontiers in Immunology, 13, http://dx.doi.org/10.3389/fimmu.2022.833699

Haifer C; Paramsothy S; Kaakoush NO; Saikal A; Ghaly S; Yang T; Luu LDW; Borody TJ; Leong RW, 2022, 'Lyophilised oral faecal microbiota transplantation for ulcerative colitis (LOTUS): a randomised, double-blind, placebo-controlled trial', The Lancet Gastroenterology and Hepatology, 7, pp. 141 - 151, http://dx.doi.org/10.1016/S2468-1253(21)00400-3

Lu LDW; Singh H; Castaño-Rodríguez N; Leach ST; Riordan SM; Tedla N; Krishnan U; Kaakoush NO, 2022, 'Changes to the upper gastrointestinal microbiotas of children with reflux oesophagitis and oesophageal metaplasia', Microbial Genomics, 8, http://dx.doi.org/10.1099/mgen.0.000870

Xu Z; Hu D; Luu LDW; Octavia S; Keil AD; Sintchenko V; Tanaka MM; Mooi FR; Robson J; Lan R, 2022, 'Genomic dissection of the microevolution of Australian epidemic Bordetella pertussis', Emerging Microbes and Infections, 11, pp. 1460 - 1473, http://dx.doi.org/10.1080/22221751.2022.2077129

Li J; Luu LDW; Wang X; Cui XD; Huang X; Fu J; Zhu X; Li Z; Wang Y; Tai J, 2022, 'Metabolomic analysis reveals potential biomarkers and the underlying pathogenesis involved in Mycoplasma pneumoniae pneumonia', Emerging Microbes and Infections, 11, pp. 593 - 605, http://dx.doi.org/10.1080/22221751.2022.2036582

Luu LDW; Lan R, 2022, 'Rapid Surface Shaving for Proteomic Identification of Novel Surface Antigens for Vaccine Development', , 2414, pp. 47 - 62, http://dx.doi.org/10.1007/978-1-0716-1900-1_4

Don Wai Luu L; Kaakoush NO; Castaño-Rodríguez N, 2022, 'The role of ATG16L2 in autophagy and disease', Autophagy, 18, pp. 2537 - 2546, http://dx.doi.org/10.1080/15548627.2022.2042783

Luu LDW; Payne M; Zhang X; Luo L; Lan R, 2021, 'Development and comparison of novel multiple cross displacement amplification (MCDA) assays with other nucleic acid amplification methods for SARS-CoV-2 detection', Scientific Reports, 11, pp. 1873, http://dx.doi.org/10.1038/s41598-021-81518-8

Li S; Huang J; Ren L; Jiang W; Wang M; Zhuang L; Zheng Q; Yang R; Zeng Y; Luu LDW; Wang Y; Tai J, 2021, 'A one-step, one-pot CRISPR nucleic acid detection platform (CRISPR-top): Application for the diagnosis of COVID-19', Talanta, 233, http://dx.doi.org/10.1016/j.talanta.2021.122591

Luu LDW; Zhong L; Kaur S; Raftery MJ; Lan R, 2021, 'Comparative Phosphoproteomics of Classical Bordetellae Elucidates the Potential Role of Serine, Threonine and Tyrosine Phosphorylation in Bordetella Biology and Virulence', Frontiers in Cellular and Infection Microbiology, 11, http://dx.doi.org/10.3389/fcimb.2021.660280

Payne M; Octavia S; Luu LDW; Sotomayor-Castillo C; Wang Q; Tay ACY; Sintchenko V; Tanaka MM; Lan R, 2021, 'Enhancing genomics-based outbreak detection of endemic salmonella enterica serovar typhimurium using dynamic thresholds', Microbial Genomics, 7, pp. 000310, http://dx.doi.org/10.1099/MGEN.0.000310

Wang Y; Wang X; Wai Luu LD; Chen S; Jin F; Wang S; Huang X; Wang L; Zhou X; Chen X; Cui X; Li J; Tai J; Zhu X, 2021, 'Proteomic and metabolomic signatures associated with the immune response in healthy individuals immunized with an inactivated SARS-CoV-2 vaccine', , http://dx.doi.org/10.1101/2021.07.21.21260959

Kaur S; Peters TJ; Yang P; Luu LDW; Vuong J; Krycer JR; O’Donoghue SI, 2020, 'Temporal ordering of omics and multiomic events inferred from time-series data', npj Systems Biology and Applications, 6, http://dx.doi.org/10.1038/s41540-020-0141-0

Liu F; Chen S; Luu LDW; Lee SA; Tay ACY; Wu R; Riordan SM; Lan R; Liu L; Zhang L, 2020, 'Analysis of complete Campylobacter concisus genomes identifies genomospecies features, secretion systems and novel plasmids and their association with severe ulcerative colitis', Microbial Genomics, http://dx.doi.org/10.1099/mgen.0.000457

James LJ; Saglimbene V; Wong G; Tong A; Luu LDW; Craig J; Howard K; Howell M, 2020, 'Behavioural and pharmaceutical interventions for the prevention of skin cancers in solid organ transplant recipients: A systematic review of randomised controlled trials', BMJ Open, 10, http://dx.doi.org/10.1136/bmjopen-2019-029265

Luu LDW; Octavia S; Aitken C; Zhong L; Raftery MJ; Sintchenko V; Lan R, 2020, 'Surfaceome analysis of Australian epidemic Bordetella pertussis reveals potential vaccine antigens', Vaccine, 38, pp. 539 - 548, http://dx.doi.org/10.1016/j.vaccine.2019.10.062

Wai Luu LD; Payne M; Zhang X; Luo L; Lan R, 2020, 'Development and comparison of a novel multiple cross displacement amplification (MCDA) assay with other nucleic acid amplification methods for SARS-CoV-2 detection', , http://dx.doi.org/10.1101/2020.10.03.20206193

Kaur S; Peters T; Yang P; Luu LDW; Vuong J; Krycer J; O’Donoghue S, 2020, 'Temporal ordering of omics and multiomic events inferred from time series data', , http://dx.doi.org/10.1101/2020.04.14.040527

Xu Z; Octavia S; Luu LDW; Payne M; Timms V; Tay CY; Keil AD; Sintchenko V; Guiso N; Lan R, 2019, 'Pertactin-negative and filamentous hemagglutinin-negative Bordetella pertussis, Australia, 2013-2017', Emerging Infectious Diseases, 25, pp. 1196 - 1199, http://dx.doi.org/10.3201/eid2506.180240

Kamachi K; Otsuka N; Fumimoto R; Ozawa K; Yao SM; Chiang CS; Luu LDW; Lan R; Shibayama K; Watanabe M, 2019, 'A novel multilocus variable-number tandem repeat analysis for Bordetella parapertussis', Journal of Medical Microbiology, 68, pp. 1671 - 1676, http://dx.doi.org/10.1099/jmm.0.001095

Luu LDW, 2019, 'Pathogen adaptation to vaccination: The Australian Bordetella pertussis story', Microbiology Australia, 40, pp. 177 - 180, http://dx.doi.org/10.1071/MA19052

Wai Luu LD; Octavia S; Zhong L; Raftery MJ; Sintchenko V; Lan R, 2018, 'Comparison of the whole cell proteome and secretome of epidemic bordetella pertussis strains from the 2008–2012 Australian epidemic under sulfate-modulating conditions', Frontiers in Microbiology, 9, http://dx.doi.org/10.3389/fmicb.2018.02851

Luu LDW; Octavia S; Zhong L; Raftery MJ; Sintchenko V; Lan R, 2018, 'Proteomic Adaptation of Australian Epidemic Bordetella pertussis', Proteomics, 18, http://dx.doi.org/10.1002/pmic.201700237

Luu LDW; Octavia S; Zhong L; Raftery M; Sintchenko V; Lan R, 2017, 'Characterisation of the Bordetella pertussis secretome under different media', Journal of Proteomics, 158, pp. 43 - 51, http://dx.doi.org/10.1016/j.jprot.2017.02.010

Safarchi A; Octavia S; Luu LDW; Tay CY; Sintchenko V; Wood N; Marshall H; McIntyre P; Lan R, 2016, 'Better colonisation of newly emerged Bordetella pertussis in the co-infection mouse model study', Vaccine, 34, pp. 3967 - 3971, http://dx.doi.org/10.1016/j.vaccine.2016.06.052

Safarchi A; Octavia S; Luu LDW; Tay CY; Sintchenko V; Wood N; Marshall H; McIntyre P; Lan R, 2015, 'Pertactin negative Bordetella pertussis demonstrates higher fitness under vaccine selection pressure in a mixed infection model', Vaccine, 33, pp. 6277 - 6281, http://dx.doi.org/10.1016/j.vaccine.2015.09.064

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